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$133+ Cheap flights from Iowa to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAN
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Iowa to Mississippi

Keep the following information in mind while searching for Iowa to Mississippi flight deals. Data was last updated September 16, 2025.

Round-trip from

$249
(Delta)

One-way from

$133
(American Airlines)
From Iowa to Mississippi
Search Deals
One-way flight from Iowa to Mississippi
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Find flight deals from Iowa to Mississippi

Cheapest flights from Iowa to Mississippi
Explore the most affordable flight options available from Iowa to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:15 pmDSM - BTR
1 stop5h 41mDelta
Sat 12/136:00 amBTR - DSM
1 stop7h 30mDelta
Deal found 9/14$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmDSM - MOB
1 stop5h 33mDelta
Wed 10/295:43 amMOB - DSM
1 stop4h 22mDelta
Deal found 9/15$249
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:02 pmOMA - GPT
1 stop7h 44mAmerican Airlines
Tue 10/285:45 pmGPT - OMA
1 stop5h 54mAmerican Airlines
Deal found 9/16$249
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/181:57 pmOMA - MOB
1 stop7h 58mAmerican Airlines
Sat 10/255:12 amMOB - OMA
1 stop5h 27mAmerican Airlines
Deal found 9/14$250
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:15 amDSM - BTR
1 stop6h 55mUnited Airlines
Wed 10/89:45 amBTR - DSM
1 stop4h 28mUnited Airlines
Deal found 9/14$254
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:15 amDSM - BTR
1 stop6h 55mUnited Airlines
Sat 10/44:05 pmBTR - DSM
1 stop6h 23mUnited Airlines
Deal found 9/15$259
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:04 amOMA - MOB
1 stop7h 21mAmerican Airlines
Sat 10/412:33 pmMOB - OMA
1 stop4h 47mAmerican Airlines
Deal found 9/15$259
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:15 amOMA - BTR
1 stop7h 37mDelta
Sat 10/44:39 pmBTR - OMA
1 stop7h 17mDelta
Deal found 9/15$259
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:57 pmOMA - GPT
1 stop5h 42mDelta
Wed 10/16:04 pmGPT - OMA
1 stop5h 52mDelta
Deal found 9/13$259
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/303:06 pmOMA - MOB
1 stop6h 42mUnited Airlines
Sat 10/411:30 amMOB - OMA
2 stops8h 26mUnited Airlines
Deal found 9/15$264
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:08 amOMA - BTR
2 stops9h 55mAmerican Airlines
Sat 10/48:13 amBTR - OMA
1 stop5h 53mAmerican Airlines
Deal found 9/15$264
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:32 pmDSM - MEM
1 stop4h 24mDelta
Thu 11/612:29 pmMEM - DSM
1 stop5h 15mDelta
Deal found 9/15$265

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Iowa to Mississippi that are best for you.

Fly from

Iowa

Fly to

Mississippi

Route

Depart

Return

Price

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Wed 12/10

2:15 pm-9:52 pm

1 stop7h 37m

Baton Rouge Ryan

Sat 12/13

6:00 am-1:30 pm

1 stop7h 30m

$249

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Thu 11/20

11:30 am-5:42 pm

1 stop6h 12m

Baton Rouge Ryan

Mon 11/24

6:33 pm-11:11 pm

1 stop4h 38m

$249

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Tue 10/14

3:06 pm-7:55 pm

1 stop4h 49m

Gulfport Biloxi Regional

Tue 10/21

5:25 pm-10:26 pm

1 stop5h 01m

$249

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 10/14

2:13 pm-9:47 pm

1 stop7h 34m

Baton Rouge Ryan

Tue 10/21

3:40 pm-10:30 pm

1 stop6h 50m

$249

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 10/18

3:48 pm-11:18 pm

1 stop7h 30m

Mobile

Sat 10/25

6:21 pm-11:16 pm

1 stop4h 55m

$249

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 10/25

5:15 pm-10:48 pm

1 stop5h 33m

Mobile

Wed 10/29

5:43 am-10:05 am

1 stop4h 22m

$249

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Wed 10/22

3:02 pm-10:46 pm

1 stop7h 44m

Gulfport Biloxi Regional

Tue 10/28

5:45 pm-11:39 pm

1 stop5h 54m

$249

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 3/3

5:15 pm-10:59 pm

1 stop5h 44m

Mobile

Sat 3/7

5:55 am-10:23 am

1 stop4h 28m

$249

OmahaMobile

OMA - MOB

OMAMOB

Omaha Eppley Airfield

Sat 10/18

1:57 pm-9:55 pm

1 stop7h 58m

Mobile

Sat 10/25

5:12 am-10:39 am

1 stop5h 27m

$250

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 9/30

6:15 am-1:10 pm

1 stop6h 55m

Baton Rouge Ryan

Wed 10/8

9:45 am-2:13 pm

1 stop4h 28m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 50 results
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Best time to book a flight from Iowa to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Mississippi

What is the cheapest month to book a flight from Iowa to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $371). Flying from Iowa to Mississippi in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 16, 2025.
Get a feel of what it's like to fly with American Airlines from Iowa to Mississippi by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Overall

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Overall

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Iowa to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Mississippi?

    A quick flight from Iowa to Mississippi can take about 4h 49m. Delta provides one of the quickest options available for as low as $249. There are 843 mi between Iowa and Mississippi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Iowa to Mississippi one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $133. Delta flights start at $149 while deals on United Airlines start at $194 one-way.

  • Can I find deals for flights from Iowa to Mississippi that include hotel bookings?

    Yes. In addition to deals on Iowa to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Mississippi.

  • Can I find deals for business class flights from Iowa to Mississippi?

    Yes. Cheapflights offers flight deals from Iowa to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $371). Flying from Iowa to Mississippi in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Iowa to Mississippi

Discover the top airline that operate flights from Iowa to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$356FlexibilityNo cancel feeOn-time71%

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