HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mississippi

$98+ Cheap flights from Iowa to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAN
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Mississippi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Mississippi

Keep the following information in mind while searching for Iowa to Mississippi flight deals. Data was last updated July 31, 2025.

Round-trip from

$197
(Delta)

One-way from

$98
(American Airlines)
From Iowa to Mississippi
Search Deals
One-way flight from Iowa to Mississippi
Search Deals

Find flight deals from Iowa to Mississippi

Cheapest flights from Iowa to Mississippi
Explore the most affordable flight options available from Iowa to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:00 amDSM - MEM
1 stop5h 07mDelta
Sat 9/206:00 amMEM - DSM
1 stop4h 14mDelta
Deal found 7/30$197
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/134:09 pmDSM - MEM
1 stop6h 48mAmerican Airlines
Sat 9/209:48 amMEM - DSM
2 stops8h 21mAmerican Airlines
Deal found 7/30$202
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:30 amMLI - MEM
1 stop7h 28mAmerican Airlines
Sun 10/55:18 pmMEM - MLI
1 stop6h 30mAmerican Airlines
Deal found 7/30$229
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:15 amOMA - MEM
1 stop6h 26mDelta
Tue 9/25:00 pmMEM - OMA
1 stop7h 05mDelta
Deal found 7/29$237
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2712:01 pmOMA - MEM
2 stops8h 15mAmerican Airlines
Tue 9/28:50 amMEM - OMA
1 stop5h 20mAmerican Airlines
Deal found 7/31$242
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:20 amDSM - MEM
2 stops9h 30mSouthwest
Fri 10/317:50 amMEM - DSM
2 stops12h 05mSouthwest
Deal found 7/30$246
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:23 pmOMA - MOB
1 stop4h 55mAmerican Airlines
Sat 10/255:12 amMOB - OMA
1 stop5h 27mAmerican Airlines
Deal found 7/30$248
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:40 pmMLI - MOB
1 stop5h 22mAmerican Airlines
Mon 9/295:11 amMOB - MLI
1 stop5h 13mAmerican Airlines
Deal found 7/29$249
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:30 pmDSM - MOB
1 stop4h 46mDelta
Sat 8/236:00 amMOB - DSM
1 stop4h 38mDelta
Deal found 7/29$249
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:57 amCID - MOB
1 stop5h 30mDelta
Tue 8/265:00 pmMOB - CID
1 stop5h 55mDelta
Deal found 7/29$249
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:15 amOMA - MOB
1 stop6h 12mDelta
Tue 8/266:00 amMOB - OMA
1 stop4h 38mDelta
Deal found 7/28$249
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:24 pmOMA - BTR
1 stop5h 42mAmerican Airlines
Mon 9/224:31 pmBTR - OMA
1 stop6h 51mAmerican Airlines
Deal found 7/29$249

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Iowa to Mississippi that are best for you.

Fly from

Iowa

Fly to

Mississippi

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 9/13

6:00 am-11:07 am

1 stop5h 07m

Memphis

Sat 9/20

6:00 am-10:14 am

1 stop4h 14m

$197

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 9/13

4:09 pm-10:57 pm

1 stop6h 48m

Memphis

Sat 9/20

9:48 am-6:09 pm

2 stops8h 21m

$202

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Fri 10/3

6:30 am-1:58 pm

1 stop7h 28m

Memphis

Sun 10/5

5:18 pm-11:48 pm

1 stop6h 30m

$229

OmahaMemphis

OMA - MEM

OMAMEM

Omaha Eppley Airfield

Thu 8/28

5:15 am-11:41 am

1 stop6h 26m

Memphis

Tue 9/2

5:00 pm-12:05 am

1 stop7h 05m

$237

OmahaMemphis

OMA - MEM

OMAMEM

Omaha Eppley Airfield

Wed 8/27

12:01 pm-8:16 pm

2 stops8h 15m

Memphis

Tue 9/2

8:50 am-2:10 pm

1 stop5h 20m

$242

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 10/28

6:20 am-3:50 pm

2 stops9h 30m

Memphis

Fri 10/31

7:50 am-7:55 pm

2 stops12h 05m

$246

OmahaMobile

OMA - MOB

OMAMOB

Omaha Eppley Airfield

Sat 10/18

11:38 am-5:51 pm

1 stop6h 13m

Mobile

Sat 10/25

5:12 am-10:39 am

1 stop5h 27m

$248

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 8/19

6:30 pm-11:16 pm

1 stop4h 46m

Mobile

Sat 8/23

6:00 am-10:38 am

1 stop4h 38m

$249

Cedar RapidsMobile

CID - MOB

CIDMOB

Cedar Rapids

Sat 8/23

5:57 am-11:27 am

1 stop5h 30m

Mobile

Tue 8/26

5:00 pm-10:55 pm

1 stop5h 55m

$249

MolineMobile

MLI - MOB

MLIMOB

Moline Quad-City

Mon 9/22

5:40 pm-11:02 pm

1 stop5h 22m

Mobile

Mon 9/29

5:11 am-10:24 am

1 stop5h 13m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 44 results
1
2
3
...
5

Best time to book a flight from Iowa to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Mississippi

What is the cheapest month to book a flight from Iowa to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $371). Flying from Iowa to Mississippi in March is currently the most expensive (average of $449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Iowa to Mississippi by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to Mississippi one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $98. Southwest flights start at $175 while deals on Delta start at $214 one-way.

  • Can I find deals for flights from Iowa to Mississippi that include hotel bookings?

    Yes. In addition to deals on Iowa to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Mississippi.

  • Can I find deals for business class flights from Iowa to Mississippi?

    Yes. Cheapflights offers flight deals from Iowa to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $371). Flying from Iowa to Mississippi in March is currently the most expensive (average of $449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Fort Lauderdale flights
Dallas/Fort Worth to LaGuardia flights
John F Kennedy Intl to Los Angeles flights
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Las Vegas flights
Los Angeles to Newark flights
Dallas/Fort Worth to O'Hare Intl flights
Los Angeles to Las Vegas flights
Newark to O'Hare Intl flights
Newark to Los Angeles flights
LaGuardia to O'Hare Intl flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Miami flights
Dallas/Fort Worth to Seattle flights
Dallas/Fort Worth to Las Vegas flights
San Francisco to John F Kennedy Intl flights
Newark to Orlando flights
John F Kennedy Intl to O'Hare Intl flights
O'Hare Intl to LaGuardia flights
John F Kennedy Intl to Seattle flights
John F Kennedy Intl to San Francisco flights
Newark to Miami flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Newark flights
Los Angeles to Honolulu flights
LaGuardia to Miami flights
Los Angeles to Seattle flights
LaGuardia to Dallas/Fort Worth flights
Atlanta to John F Kennedy Intl flights
Newark to Seattle flights
Fort Lauderdale to Newark flights
O'Hare Intl to Dallas/Fort Worth flights
Los Angeles to O'Hare Intl flights
Dallas/Fort Worth to Los Angeles flights
Newark to San Francisco flights
Los Angeles to Dallas/Fort Worth flights
Dallas/Fort Worth to Newark flights
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Atlanta flights
LaGuardia to Orlando flights
Dallas/Fort Worth to Denver flights
Los Angeles to LaGuardia flights
San Francisco to Newark flights
San Francisco to Seattle flights
Atlanta to LaGuardia flights
Dallas/Fort Worth to John F Kennedy Intl flights
LaGuardia to Atlanta flights
Ontario to San Francisco flights
Hobby to LaGuardia flights

Top 2 airlines flying from Iowa to Mississippi

Discover the top 2 airlines that operate flights from Iowa to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$328FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$351FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.