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Mississippi

$164+ Cheap flights from Iowa to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAN
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Iowa to Mississippi

Cheapest flights from Iowa to Mississippi
Explore the most affordable flight options available from Iowa to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:35 am
DSM
-
MOB
1 stop6h 20m
Delta
Wed 4/86:15 am
MOB
-
DSM
1 stop4h 33m
Delta
Deal found 2/2$269
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am
CID
-
MOB
1 stop5h 48m
Delta
Fri 10/304:15 pm
MOB
-
CID
1 stop5h 36m
Delta
Deal found 2/4$269
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:07 pm
OMA
-
MOB
1 stop6h 37m
American Airlines
Sat 4/2510:49 am
MOB
-
OMA
1 stop5h 33m
American Airlines
Deal found 2/3$269
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/75:05 am
CID
-
GPT
1 stop5h 08m
American Airlines
Tue 3/105:00 am
GPT
-
CID
1 stop7h 37m
American Airlines
Deal found 2/2$271
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:05 pm
CID
-
MOB
2 stops10h 52m
Delta
Wed 10/284:15 pm
MOB
-
CID
1 stop5h 36m
Delta
Deal found 2/4$274
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:15 am
OMA
-
MOB
1 stop5h 35m
United Airlines
Sat 4/259:00 am
MOB
-
OMA
2 stops11h 27m
United Airlines
Deal found 2/2$274
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:04 pm
MLI
-
MEM
1 stop3h 59m
American Airlines
Thu 3/125:00 am
MEM
-
MLI
1 stop7h 11m
American Airlines
Deal found 2/3$274
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/172:00 pm
DSM
-
BTR
1 stop5h 26m
American Airlines
Sat 2/215:00 am
BTR
-
DSM
1 stop5h 44m
American Airlines
Deal found 2/1$279
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/177:01 am
OMA
-
BTR
1 stop5h 50m
American Airlines
Sat 2/214:31 pm
BTR
-
OMA
1 stop7h 44m
American Airlines
Deal found 2/2$279
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:19 pm
CID
-
MOB
2 stops6h 39m
Delta
Sat 2/215:00 pm
MOB
-
CID
1 stop4h 24m
Delta
Deal found 2/2$284
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:48 pm
DSM
-
MEM
1 stop8h 53m
American Airlines
Sun 3/87:23 pm
MEM
-
DSM
1 stop4h 17m
American Airlines
Deal found 2/1$289
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:05 am
CID
-
GPT
1 stop5h 08m
American Airlines
Tue 3/105:00 am
GPT
-
CID
1 stop7h 37m
American Airlines
Deal found 2/2$290

Find flight deals from Iowa to Mississippi

Keep the following information in mind while searching for Iowa to Mississippi flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

One-way from

$164
(Delta)
Provider with most accurate pricing for Des Moines-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Jackson-Evers Intl flights.
Search Deals
From Iowa to Mississippi
Search Deals
One-way flight from Iowa to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Iowa to Mississippi that are best for you.

Fly from

Iowa

Fly to

Mississippi

Route

Depart

Return

Price

Cedar RapidsMobile

CID - MOB

CIDMOB

Cedar Rapids

Sat 5/2

1:14 pm-7:01 pm

1 stop5h 47m

Mobile

Wed 5/6

4:49 pm-11:58 pm

1 stop7h 09m

$269

OmahaMobile

OMA - MOB

OMAMOB

Omaha Eppley Airfield

Sat 4/18

5:07 pm-11:44 pm

1 stop6h 37m

Mobile

Sat 4/25

6:33 pm-12:22 am

1 stop5h 49m

$269

Cedar RapidsGulfport

CID - GPT

CIDGPT

Cedar Rapids

Sat 3/7

5:05 am-10:13 am

1 stop5h 08m

Gulfport Biloxi Regional

Tue 3/10

5:00 am-12:37 pm

1 stop7h 37m

$271

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 4/1

4:25 pm-11:28 pm

2 stops7h 03m

Mobile

Wed 4/8

6:15 am-10:48 am

1 stop4h 33m

$274

OmahaMobile

OMA - MOB

OMAMOB

Omaha Eppley Airfield

Sat 4/18

6:15 am-11:50 am

1 stop5h 35m

Mobile

Sat 4/25

9:00 am-8:27 pm

2 stops11h 27m

$274

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Thu 3/5

8:04 pm-12:03 am

1 stop3h 59m

Memphis

Thu 3/12

5:00 am-12:11 pm

1 stop7h 11m

$274

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 2/17

2:00 pm-7:26 pm

1 stop5h 26m

Baton Rouge Ryan

Sat 2/21

5:00 am-10:44 am

1 stop5h 44m

$279

OmahaBaton Rouge

OMA - BTR

OMABTR

Omaha Eppley Airfield

Tue 2/17

7:01 am-12:51 pm

1 stop5h 50m

Baton Rouge Ryan

Sat 2/21

4:31 pm-12:15 am

1 stop7h 44m

$279

OmahaBaton Rouge

OMA - BTR

OMABTR

Omaha Eppley Airfield

Fri 2/20

3:00 pm-9:36 pm

1 stop6h 36m

Baton Rouge Ryan

Mon 2/23

4:28 pm-12:15 am

1 stop7h 47m

$279

Cedar RapidsMobile

CID - MOB

CIDMOB

Cedar Rapids

Tue 2/17

4:19 pm-10:58 pm

2 stops6h 39m

Mobile

Sat 2/21

5:00 pm-9:24 pm

1 stop4h 24m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Mississippi

What is the cheapest month to book a flight from Iowa to Mississippi?

Currently, August is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $248). Flying from Iowa to Mississippi in November is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated February 4, 2026.
Get a feel of what it's like to fly with American Airlines from Iowa to Mississippi by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,222 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,222 reviews
American Airlines
7.2
Good
11,222 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Mississippi?

    A quick flight from Iowa to Mississippi can take about 5h 35m. American Airlines provides one of the quickest options available for as low as $274. There are 848 mi between Iowa and Mississippi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Iowa to Mississippi that include hotel bookings?

    Yes. In addition to deals on Iowa to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Mississippi.

  • Can I find deals for business class flights from Iowa to Mississippi?

    Yes. Cheapflights offers flight deals from Iowa to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Mississippi?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $248). Flying from Iowa to Mississippi in November is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Iowa to Mississippi

Discover the top airline that operate flights from Iowa to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$328FlexibilityNo cancel feeOn-time71%

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