In terms of precipitation, rainfall in Mississippi ranges from 2.2 - 5.6 inches per month. December is typically the wettest month, when rainfall can reach 5.6 in. October is typically the driest time to visit Mississippi when rainfall is around 2.2 in.

If weather is an important factor for your trip to Mississippi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

What are the most popular routes from Florence, South Carolina to Mississippi?

The most popular flight routes from Florence, South Carolina to Mississippi are Florence - Jackson-Evers Intl, Florence - Meridian Key Field and Florence - Laurel Hattiesburg-PineBelt.

What is the cheapest time of day to fly from FLO to MS?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florence, South Carolina to Mississippi as you normally would.

What airport do you fly from for flights from Florence to Mississippi?

For a flight from Florence to Mississippi, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city.

Can I find deals for flights from Florence to Mississippi that include hotel bookings?

Yes. In addition to deals on Florence to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florence to Mississippi?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Mississippi.

Can I find deals for business class flights from Florence to Mississippi?

Yes. Cheapflights offers flight deals from Florence to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$402+ Cheap Flights from Florence, SC to Mississippi

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One-way

One-way flights from Florence to Mississippi
Search for one-way flight options from Florence to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.

Sat 10/102:34 pm

FLO

JAN

1 stop4h 41m

American Airlines

Deal found 7/22

$402

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FlorenceJackson

FLO - JAN

FLOJAN

Florence

Sat 10/10

2:34 pm-6:15 pm

1 stop4h 41m

$402

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Deals found on 7/22

Sorted by cheapest first

Best time to book a flight from Florence to Mississippi

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FLO-JAN

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Everything you need to know about your flight from Florence to Mississippi

FLO-USMS

FLO-JAN

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly from for flights from Florence to Mississippi?
For a flight from Florence to Mississippi, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city.
What are the most popular routes from Florence, South Carolina to Mississippi?
The most popular flight routes from Florence, South Carolina to Mississippi are Florence - Jackson-Evers Intl, Florence - Meridian Key Field and Florence - Laurel Hattiesburg-PineBelt.
Can I find deals for flights from Florence to Mississippi that include hotel bookings?
Yes. In addition to deals on Florence to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florence to Mississippi?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Mississippi.
Can I find deals for business class flights from Florence to Mississippi?
Yes. Cheapflights offers flight deals from Florence to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florence to Mississippi with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florence to Mississippi

One-way flights from Florence to Mississippi
Search for one-way flight options from Florence to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.

Search for one-way flight options from Florence to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to Mississippi that are best for you.

Best time to book a flight from Florence to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Florence with our price prediction graph.

Cheapflights Insights

Related info for your journey

What airport do you fly from for flights from Florence to Mississippi?

What are the most popular routes from Florence, South Carolina to Mississippi?

Can I find deals for flights from Florence to Mississippi that include hotel bookings?

How can I find direct flights from Florence to Mississippi?

Can I find deals for business class flights from Florence to Mississippi?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florence to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Florence to Mississippi by cabin class

Find flights from Florence to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Florence and Mississippi flights

Browse other Florence and Mississippi flight options. Last updated on July 25, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

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$402+ Cheap flights from Florence, SC (FLO) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florence to Mississippi with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florence to Mississippi

One-way flights from Florence to MississippiSearch for one-way flight options from Florence to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.

Search for one-way flight options from Florence to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to Mississippi that are best for you.

Best time to book a flight from Florence to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Florence with our price prediction graph.

Cheapflights Insights

Related info for your journey

What airport do you fly from for flights from Florence to Mississippi?

What are the most popular routes from Florence, South Carolina to Mississippi?

Can I find deals for flights from Florence to Mississippi that include hotel bookings?

How can I find direct flights from Florence to Mississippi?

Can I find deals for business class flights from Florence to Mississippi?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florence to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Florence to Mississippi by cabin class

Find flights from Florence to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Florence and Mississippi flights

Browse other Florence and Mississippi flight options. Last updated on July 25, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

100% Free

Book with Flexibility

Travel Smart

One-way flights from Florence to Mississippi
Search for one-way flight options from Florence to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.