$372+ Cheap flights from Florence, SC (FLO) to Mississippi
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — JAN
Feb 28 — Mar 71
1 adult, Economy
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1. Tell us where you want to go
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Cheapest flights from Florence to MississippiExplore the most affordable flight options available from Florence to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from Florence to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:58 pm
FLO
- JAN
1 stop5h 58m
American Airlines
Wed 3/181:08 pm
JAN
- FLO
1 stop3h 42m
American Airlines
Deal found 1/27![American Airlines logo]()
$437
Find flight deals from Florence to Mississippi
Keep the following information in mind while searching for Florence to Mississippi flight deals. Data was last updated January 29, 2026.
Round-trip from | $437 (American Airlines) |
|---|---|
One-way from | $372 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Florence to Mississippi that are best for you.
Fly from
Florence
Fly to
Mississippi
Route
Depart
Return
Price
FlorenceJackson
FLO - JAN
FLOJAN
Florence
Wed 3/4
5:58 pm-10:56 pm
1 stop5h 58m
Jackson-Evers Intl
Wed 3/18
1:08 pm-5:50 pm
1 stop3h 42m
$437
FlorenceJackson
FLO - JAN
FLOJAN
Florence
Wed 3/4
5:58 pm-10:56 pm
1 stop5h 58m
$372
Best time to book a flight from Florence to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Mississippi
What is the cheapest month to book a flight from Florence, South Carolina to Mississippi?
Currently, April is the cheapest month in which you can book a flight from Florence, South Carolina to Mississippi (average of $165). Flying from Florence, South Carolina to Mississippi in October is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.