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$402+ Cheap flights from Florence, SC (FLO) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — JAN
Jul 20 — Jul 271
Mon 7/20
Mon 7/27
1 adult, Economy
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Cheap flight deals from Florence to Mississippi

Cheapest flights from Florence to Mississippi
Explore the most affordable flight options available from Florence to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.

This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:17 am
FLO
-
JAN
1 stop6h 11m
American Airlines
Thu 7/97:20 am
JAN
-
FLO
1 stop5h 50m
American Airlines
Deal found 6/19$853

Find flight deals from Florence to Mississippi

Keep the following information in mind while searching for Florence to Mississippi flight deals. Data was last updated June 20, 2026.

Round-trip from

$853
(American Airlines)

One-way from

$402
(American Airlines)
From Florence to Mississippi
Search Deals
One-way flight from Florence to Mississippi
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Florence to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceJackson

FLO - JAN

FLOJAN

Florence

Sun 7/5

5:17 am-10:28 am

1 stop6h 11m

Jackson-Evers Intl

Thu 7/9

7:20 am-2:10 pm

1 stop5h 50m

$853
Cheapest one-way
Quickest one-way

FlorenceJackson

FLO - JAN

FLOJAN

Florence

Tue 10/13

5:22 am-10:26 am

1 stop6h 04m

$402

FlorenceJackson

FLO - JAN

FLOJAN

Florence

Mon 10/12

11:07 am-11:26 pm

2 stops13h 19m

$1,077

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Sorted by cheapest first

Best time to book a flight from Florence to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Mississippi
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Florence to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Mississippi?

    For a flight from Florence to Mississippi, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from Florence, South Carolina to Mississippi?

    A quick flight from Florence, South Carolina to Mississippi can take about 6h 11m. American Airlines provides one of the quickest options available for as low as $853. The distance from Florence, South Carolina to Mississippi is about 611 mi.

  • What are the most popular routes from Florence, South Carolina to Mississippi?

    The most popular flight routes from Florence, South Carolina to Mississippi are Florence - Jackson-Evers Intl, Florence - Meridian Key Field and Florence - Laurel Hattiesburg-PineBelt.

  • Can I find deals for flights from Florence to Mississippi that include hotel bookings?

    Yes. In addition to deals on Florence to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Mississippi.

  • Can I find deals for business class flights from Florence to Mississippi?

    Yes. Cheapflights offers flight deals from Florence to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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