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$245+ Cheap flights from Des Moines to Medford (DSM - MFR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFR
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Des Moines to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$304
(Delta)

One-way from

$245
(United Airlines)

Popular in

June

Cheapest in

January

Average price

$534
From Des Moines to Medford
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One-way flight from Des Moines to Medford
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Highest demand for flights based on searches. 27% potential increase in price ($196 potential increase over avg. RT price).
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Cheapest flight prices on average. 14% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Medford

Cheapest flights from Des Moines to Medford
Explore the most affordable flight options available from Des Moines to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/233:30 pmDSM - MFR
2 stops8h 51mDelta
Tue 8/266:00 amMFR - DSM
2 stops9h 12mDelta
Deal found 7/28$304
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2311:35 amDSM - MFR
2 stops12h 44mUnited Airlines
Tue 8/265:00 amMFR - DSM
1 stop5h 36mUnited Airlines
Deal found 7/27$354
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:30 amDSM - MFR
1 stop9h 40mAmerican Airlines
Mon 8/181:52 pmMFR - DSM
1 stop8h 22mAmerican Airlines
Deal found 7/27$398
This Mytrip deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/76:30 amDSM - MFR
3 stops34h 10mMultiple Airlines
Mon 8/119:03 pmMFR - DSM
2 stops16h 45mMultiple Airlines
Deal found 7/26$706
This Alaska Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/113:21 pmDSM - MFR
2 stops10h 49mAlaska Airlines
Fri 8/156:14 pmMFR - DSM
2 stops12h 17mAlaska Airlines
Deal found 7/27$746

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Des Moines to Medford that are best for you.

Fly from

Des Moines

Fly to

Medford

Route

Depart

Return

Price

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sat 8/23

3:30 pm-10:21 pm

2 stops8h 51m

Medford

Tue 8/26

6:00 am-5:12 pm

2 stops9h 12m

$304

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sat 8/23

11:35 am-10:19 pm

2 stops12h 44m

Medford

Tue 8/26

5:00 am-12:36 pm

1 stop5h 36m

$354

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Wed 8/13

5:30 am-1:10 pm

1 stop9h 40m

Medford

Mon 8/18

1:52 pm-12:14 am

1 stop8h 22m

$398

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Thu 8/7

6:30 am-2:40 pm

3 stops34h 10m

Medford

Mon 8/11

9:03 pm-3:48 pm

2 stops16h 45m

$706

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Mon 8/11

3:21 pm-12:10 am

2 stops10h 49m

Medford

Fri 8/15

6:14 pm-8:31 am

2 stops12h 17m

$746

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Wed 8/27

8:00 am-10:19 pm

3 stops16h 19m

$245

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Wed 8/27

7:32 am-5:06 pm

2 stops11h 34m

$285

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Wed 8/27

5:30 am-1:10 pm

1 stop9h 40m

$295

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Des Moines to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Medford

How much does it cost to fly round-trip from Des Moines to Medford?

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta, and United Airlines from Des Moines to Medford by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,979 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,896 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Boarding

8.1

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Medford round-trip?

    According to our current data, Delta ($304), United Airlines ($354), and American Airlines ($398) offers the cheapest pricing from Des Moines to Medford. Delta is 42% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Des Moines to Medford one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $245. Users have also found prices from $285 and $295 on Alaska Airlines and American Airlines, respectively.

  • Can I find deals for flights from Des Moines to Medford that include hotel bookings?

    Yes. In addition to deals on Des Moines to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Medford.

  • Can I find deals for business class flights from Des Moines to Medford?

    Yes. Cheapflights offers flight deals from Des Moines to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Medford?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Medford (average of $349). Flying from Des Moines to Medford in June is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Yreka

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Top 2 airlines flying from Des Moines to Medford

Discover the top 2 airlines that operate flights from Des Moines to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$268Average$408FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$349Average$498FlexibilityNo cancel feeOn-time69%

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