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$279+ Cheap flights from Des Moines to Medford (DSM - MFR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFR
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$279
(Delta)

Popular in

June

Cheapest in

January

Average price

$520
From Des Moines to Medford
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($192 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($67 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Medford

Cheapest flights from Des Moines to Medford
Explore the most affordable flight options available from Des Moines to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:30 pmDSM - MFR
2 stops9h 20mDelta
Tue 11/45:15 amMFR - DSM
2 stops10h 01mDelta
Deal found 9/10$279
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:01 amDSM - MFR
2 stops13h 07mUnited Airlines
Tue 11/45:00 amMFR - DSM
1 stop5h 38mUnited Airlines
Deal found 9/10$290
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2611:30 amDSM - MFR
2 stops10h 59mUnited Airlines
Tue 9/305:00 amMFR - DSM
1 stop5h 37mUnited Airlines
Deal found 9/11$324
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:30 amDSM - MFR
1 stop9h 45mAmerican Airlines
Tue 11/43:00 pmMFR - DSM
1 stop6h 59mAmerican Airlines
Deal found 9/10$329
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:13 pmDSM - MFR
1 stop5h 53mUnited Airlines
Mon 9/296:37 pmMFR - DSM
2 stops13h 55mUnited Airlines
Deal found 9/9$404
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:15 pmDSM - MFR
1 stop5h 49mUnited Airlines
Wed 9/245:00 amMFR - DSM
1 stop5h 36mUnited Airlines
Deal found 9/10$429

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Medford that are best for you.

Fly from

Des Moines

Fly to

Medford

Route

Depart

Return

Price

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sat 11/1

3:30 pm-10:50 pm

2 stops9h 20m

Medford

Tue 11/4

5:15 am-5:16 pm

2 stops10h 01m

$279

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sat 11/1

9:01 am-8:08 pm

2 stops13h 07m

Medford

Tue 11/4

5:00 am-12:38 pm

1 stop5h 38m

$290

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sat 11/1

5:30 am-1:15 pm

1 stop9h 45m

Medford

Tue 11/4

3:00 pm-11:59 pm

1 stop6h 59m

$329

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Fri 9/26

6:00 am-12:07 pm

2 stops8h 07m

Medford

Tue 9/30

6:00 am-9:50 pm

2 stops13h 50m

$389

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Thu 9/25

5:13 pm-9:06 pm

1 stop5h 53m

Medford

Mon 9/29

6:37 pm-10:32 am

2 stops13h 55m

$404

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sun 10/26

5:00 am-1:58 pm

2 stops10h 58m

$330

Des MoinesMedford

DSM - MFR

DSMMFR

Des Moines

Sun 10/26

3:15 pm-10:30 pm

3 stops33h 15m

$553

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Des Moines to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from Des Moines to Medford by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Medford?

    Airlines like Delta, United Airlines, and American Airlines fly from Des Moines to Medford in about 9h 20m. The time it takes to get you to your destination can typically vary by up to 3h 47m. Des Moines and Medford are separated by a distance of 1494 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Medford round-trip?

    According to our current data, American Airlines ($268), and United Airlines ($274) offers the cheapest pricing from Des Moines to Medford. American Airlines is 49% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Des Moines to Medford that include hotel bookings?

    Yes. In addition to deals on Des Moines to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Medford.

  • Can I find deals for business class flights from Des Moines to Medford?

    Yes. Cheapflights offers flight deals from Des Moines to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Medford?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Medford (average of $349). Flying from Des Moines to Medford in June is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Yreka

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Top 2 airlines flying from Des Moines to Medford

Discover the top 2 airlines that operate flights from Des Moines to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$268Average$423FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$274Average$493FlexibilityNo cancel feeOn-time69%

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