$280+ Cheap flights from Des Moines to Medford (DSM - MFR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MFR
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Medford with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Medford
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Best
Last-minute
One-way
Cheapest flights from Des Moines to MedfordExplore the most affordable flight options available from Des Moines to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Des Moines to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:30 am
DSM
- MFR
2 stops8h 18m
United Airlines
Mon 4/206:31 pm
MFR
- DSM
2 stops14h 13m
United Airlines
Deal found 3/6![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:26 pm
DSM
- MFR
1 stop6h 38m
American Airlines
Mon 4/202:08 pm
MFR
- DSM
1 stop7h 48m
American Airlines
Deal found 3/6![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:27 pm
DSM
- MFR
1 stop6h 46m
American Airlines
Sat 3/285:14 am
MFR
- DSM
1 stop6h 33m
American Airlines
Deal found 3/9![American Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:30 am
DSM
- MFR
1 stop9h 15m
Allegiant Air
Thu 3/269:20 pm
MFR
- DSM
1 stop22h 44m
Allegiant Air
Deal found 3/7![Allegiant Air logo]()
$387
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:12 pm
DSM
- MFR
1 stop6h 25m
United Airlines
Sat 5/212:52 pm
MFR
- DSM
1 stop5h 24m
United Airlines
Deal found 3/8![United Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:30 am
DSM
- MFR
1 stop9h 15m
Multiple Airlines
Thu 3/269:20 pm
MFR
- DSM
2 stops19h 56m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$413
Best flights from Des Moines to MedfordDiscover carefully curated flight deals from Des Moines to Medford that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Des Moines to Medford that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:12 pm
DSM
- MFR
1 stop6h 25m
United Airlines
Sat 5/212:52 pm
MFR
- DSM
1 stop5h 24m
United Airlines
Deal found 3/5![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:00 am
DSM
- MFR
2 stops10h 41m
United Airlines
Sat 3/285:00 am
MFR
- DSM
1 stop5h 48m
United Airlines
Deal found 3/9![United Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:17 pm
DSM
- MFR
1 stop5h 59m
United Airlines
Sat 8/16:00 am
MFR
- DSM
2 stops8h 15m
United Airlines
Deal found 3/8![United Airlines logo]()
$494
Last-minute flights from Des Moines to MedfordDiscover last-minute flight deals from Des Moines to Medford. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Medford. Data last updated March 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:30 am
DSM
- MFR
1 stop9h 15m
Allegiant Air
Thu 3/269:20 pm
MFR
- DSM
1 stop22h 44m
Allegiant Air
Deal found 3/7![Allegiant Air logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:30 am
DSM
- MFR
1 stop9h 15m
Multiple Airlines
Thu 3/269:20 pm
MFR
- DSM
2 stops19h 56m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:27 pm
DSM
- MFR
1 stop6h 46m
American Airlines
Sat 3/285:14 am
MFR
- DSM
1 stop6h 33m
American Airlines
Deal found 3/9![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:30 am
DSM
- MFR
2 stops8h 18m
United Airlines
Mon 4/206:31 pm
MFR
- DSM
2 stops14h 13m
United Airlines
Deal found 3/6![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:26 pm
DSM
- MFR
1 stop6h 38m
American Airlines
Mon 4/202:08 pm
MFR
- DSM
1 stop7h 48m
American Airlines
Deal found 3/6![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:12 pm
DSM
- MFR
1 stop6h 25m
United Airlines
Sat 5/212:52 pm
MFR
- DSM
1 stop5h 24m
United Airlines
Deal found 3/8![United Airlines logo]()
$389
One-way flights from Des Moines to MedfordSearch for one-way flight options from Des Moines to Medford. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Des Moines to Medford. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Alaska Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:06 pm
DSM
- MFR
2 stops12h 30m
Alaska Airlines
Deal found 3/7![Alaska Airlines logo]()
$280
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:11 pm
DSM
- MFR
1 stop6h 26m
United Airlines
Deal found 3/9![United Airlines logo]()
$340
This Alaska Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:16 pm
DSM
- MFR
2 stops11h 43m
Alaska Airlines
Deal found 3/9![Alaska Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:25 pm
DSM
- MFR
2 stops9h 22m
Delta
Deal found 3/9![Delta logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/303:02 pm
DSM
- MFR
3 stops58h 57m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$558
This Alaska Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/193:20 pm
DSM
- MFR
2 stops10h 39m
Alaska Airlines
Deal found 3/5![Alaska Airlines logo]()
$630
Find flight deals from Des Moines to Medford
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (United Airlines) |
One-way from | $280 (Alaska Airlines) |
Popular in | February |
Cheapest in | December |
Average price | $476 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Des Moines to Medford that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Tue 4/28
5:12 pm-9:37 pm
1 stop6h 25m
Medford
Sat 5/2
12:52 pm-8:16 pm
1 stop5h 24m
$389
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Tue 3/24
9:00 am-5:41 pm
2 stops10h 41m
Medford
Sat 3/28
5:00 am-12:48 pm
1 stop5h 48m
$394
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Mon 7/27
5:17 pm-9:16 pm
1 stop5h 59m
Medford
Sat 8/1
6:00 am-4:15 pm
2 stops8h 15m
$494
Cheapest one-way
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Tue 4/21
12:06 pm-10:36 pm
2 stops12h 30m
$280
Quickest one-way
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Mon 3/30
5:11 pm-9:37 pm
1 stop6h 26m
$340
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Thu 4/23
2:16 pm-11:59 pm
2 stops11h 43m
$348
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Mon 3/30
4:25 pm-11:47 pm
2 stops9h 22m
$445
Des MoinesMedford
DSM - MFR
DSMMFR
Des Moines
Sun 4/19
3:20 pm-11:59 pm
2 stops10h 39m
$630
Sorted by cheapest first
Compare providers for flights from Des Moines to Medford
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Medford in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Medford flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Medford flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Medford flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Medford flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Medford flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Medford
Have a flexible travel schedule? Discover the best time to fly to Medford from Des Moines with our price prediction graph.
DSM-MFR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Medford
Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated March 10, 2026.
Get a feel of what it's like to fly with United Airlines from Des Moines to Medford by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Food
6.6
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Comfort
7.3
Food
6.6
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Medford?
Book flights to Medford if you plan to visit one of these locationsYreka
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Other flights to Medford
Explore flights to Medford departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
Des Moines and Medford flights
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Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
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Top airline flying from Des Moines to Medford
Discover the top airline that operate flights from Des Moines to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$274 | Average$487 | FlexibilityNo cancel fee | On-time69% |