$90+ Cheap flights from San Diego to Knoxville (SAN - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — TYS
Feb 20 — Feb 271
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Knoxville
Cheapest flights from San Diego to KnoxvilleExplore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.
Explore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.
This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:30 am
SAN
- TYS
1 stop6h 05m
Frontier
Mon 2/238:13 pm
TYS
- SAN
1 stop6h 55m
Frontier
Deal found 1/20![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/119:45 am
SAN
- TYS
2 stops33h 40m
Multiple Airlines
Fri 2/208:12 pm
TYS
- SAN
1 stop18h 16m
Multiple Airlines
Deal found 1/20![Multiple Airlines logo]()
$213
This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:35 am
SAN
- TYS
1 stop7h 52m
Frontier
Mon 2/238:13 pm
TYS
- SAN
1 stop6h 55m
Frontier
Deal found 1/19![Frontier logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/126:25 am
SAN
- TYS
1 stop8h 27m
Multiple Airlines
Fri 2/208:12 pm
TYS
- SAN
1 stop18h 16m
Multiple Airlines
Deal found 1/20![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:25 am
SAN
- TYS
1 stop10h 02m
Frontier
Fri 2/208:12 pm
TYS
- SAN
1 stop18h 16m
Frontier
Deal found 1/20![Frontier logo]()
$229
This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:30 am
SAN
- TYS
1 stop6h 05m
Frontier
Mon 2/168:13 pm
TYS
- SAN
1 stop6h 55m
Frontier
Deal found 1/19![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:25 am
SAN
- TYS
2 stops37h 00m
Multiple Airlines
Fri 2/208:12 pm
TYS
- SAN
1 stop18h 16m
Multiple Airlines
Deal found 1/20![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/88:16 pm
SAN
- TYS
1 stop16h 19m
Frontier
Fri 2/208:12 pm
TYS
- SAN
1 stop18h 16m
Frontier
Deal found 1/20![Frontier logo]()
$236
This Priceline deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:25 am
SAN
- TYS
1 stop6h 00m
Frontier
Mon 3/164:20 pm
TYS
- SAN
1 stop7h 13m
Frontier
Deal found 1/20![Frontier logo]()
$249
This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:35 am
SAN
- TYS
1 stop7h 52m
Frontier
Fri 2/276:51 pm
TYS
- SAN
1 stop8h 17m
Frontier
Deal found 1/19![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/126:25 am
SAN
- TYS
1 stop8h 27m
Multiple Airlines
Thu 2/265:53 pm
TYS
- SAN
2 stops43h 33m
Multiple Airlines
Deal found 1/20![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:25 am
SAN
- TYS
1 stop9h 53m
Multiple Airlines
Tue 3/109:00 am
TYS
- SAN
1 stop8h 31m
Multiple Airlines
Deal found 1/19![Multiple Airlines logo]()
$256
Find flight deals from San Diego to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $180 (Frontier) |
One-way from | $90 (Frontier) |
Popular in | November |
Cheapest in | July |
Average price | $349 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from San Diego to Knoxville that are best for you.
Fly from
San Diego
Fly to
Knoxville
Route
Depart
Return
Price
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 2/21
1:45 pm-11:44 pm
1 stop6h 59m
Knoxville McGhee Tyson
Sat 2/28
4:55 pm-11:40 pm
2 stops9h 45m
$282
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Thu 2/19
10:20 pm-9:04 am
1 stop7h 44m
Knoxville McGhee Tyson
Tue 3/3
5:35 am-10:01 am
1 stop7h 26m
$304
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 2/7
1:51 pm-11:44 pm
1 stop6h 53m
Knoxville McGhee Tyson
Sat 2/21
4:55 pm-11:40 pm
2 stops9h 45m
$354
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 5/23
10:30 pm-10:10 am
1 stop8h 40m
Knoxville McGhee Tyson
Thu 5/28
4:00 pm-9:34 pm
1 stop8h 34m
$354
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Wed 2/18
2:15 pm-11:52 pm
1 stop6h 37m
Knoxville McGhee Tyson
Fri 2/27
6:41 pm-10:48 pm
1 stop7h 07m
$354
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 3/7
3:16 pm-4:04 pm
1 stop21h 48m
Knoxville McGhee Tyson
Sun 3/15
9:43 pm-11:29 pm
2 stops28h 46m
$358
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 2/17
10:20 pm-9:04 am
1 stop7h 44m
Knoxville McGhee Tyson
Wed 2/25
5:35 am-2:31 pm
2 stops11h 56m
$367
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Wed 5/20
10:30 pm-10:10 am
1 stop8h 40m
Knoxville McGhee Tyson
Tue 5/26
4:15 pm-10:58 pm
1 stop9h 43m
$368
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 3/24
12:16 pm-11:44 pm
1 stop8h 28m
Knoxville McGhee Tyson
Tue 3/31
10:49 am-5:16 pm
2 stops9h 27m
$372
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 5/2
10:23 am-7:56 pm
1 stop6h 33m
Knoxville McGhee Tyson
Tue 5/5
7:00 am-3:39 pm
2 stops11h 39m
$372
Showing 1-10 of 21 results
Compare providers for flights from San Diego to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Knoxville in January.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Diego-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Knoxville flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Knoxville
Prices
Delays
How far ahead should I book a flight from San Diego to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Knoxville. Price data was last updated on January 16, 2026.
Booking 33 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Knoxville?
Currently, December is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $65). Flying from San Diego to Knoxville in March is currently the most expensive (average of $280). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How often are flights from San Diego to Knoxville delayed?
About 0% of weekly flights between San Diego and Knoxville have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for San Diego to Knoxville flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 21, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Diego to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy
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Alternative routes for San Diego to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from San Diego to Knoxville
Discover the top 4 airlines that operate flights from San Diego to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$65 | Average$296 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$228 | Average$465 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$442 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$389 | FlexibilityNo cancel fee | On-timeN/A |