$126+ Cheap flights from San Diego to Knoxville (SAN - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from San Diego to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Knoxville McGhee Tyson are usually found in January or July, booked 21 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday
Cheap flight deals from San Diego to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.
Round-trip from | $274 (Mytrip) |
|---|---|
One-way from | $126 (Mytrip) |
Popular in | December |
Cheapest in | January |
Average price | $452 |
Find flight deals from San Diego to Knoxville
Cheapest flights from San Diego to KnoxvilleExplore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Alaska Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from San Diego to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 7/8
6:15 am-3:19 pm
2 stops30h 04m
Knoxville McGhee Tyson
Fri 7/11
6:55 am-11:06 pm
2 stops19h 11m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 7/4
6:35 am-5:05 pm
1 stop7h 30m
Knoxville McGhee Tyson
Sat 7/12
5:46 pm-10:44 pm
1 stop7h 58m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Mon 9/8
10:20 am-7:41 pm
1 stop6h 21m
Knoxville McGhee Tyson
Thu 9/11
8:26 pm-11:50 pm
1 stop6h 24m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Wed 8/6
6:15 am-5:32 pm
1 stop8h 17m
Knoxville McGhee Tyson
Sun 8/10
5:30 am-9:23 am
1 stop6h 53m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 6/24
9:13 pm-8:33 am
1 stop8h 20m
Knoxville McGhee Tyson
Tue 7/1
5:05 am-9:00 am
1 stop6h 55m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Wed 8/6
6:15 am-10:01 pm
2 stops12h 46m
Knoxville McGhee Tyson
Tue 8/12
6:39 pm-10:30 pm
1 stop6h 51m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Thu 6/26
6:15 am-1:38 pm
1 stop28h 23m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 7/22
11:15 am-9:16 pm
1 stop7h 01m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sun 6/15
6:25 am-4:29 pm
1 stop7h 04m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 7/29
10:20 pm-10:17 am
1 stop8h 57m
Best time to book a flight from San Diego to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Diego with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Knoxville
How far ahead should I book a flight from San Diego to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Knoxville. Price data was last updated on June 9, 2025.
Booking 21 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Knoxville?
Currently, January is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $296). Flying from San Diego to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to TYS?
Find hourly flight availability from San Diego to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
It’s typically best to fly out from San Diego to Knoxville at noon. Doing so could potentially save you 22% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from San Diego to Knoxville?
Use this chart to determine the cheapest time to fly round-trip from San Diego to Knoxville. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their San Diego to Knoxville flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Rainfall in Knoxville by month
Plan your trip to Knoxville by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.
Temperature in Knoxville by month
Plan your trip to Knoxville by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta and United Airlines from San Diego to Knoxville by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
James,Apr 2025
LAX - SFO
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
James,Apr 2025
LAX - SFO
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
James,Apr 2025
LAX - SFO
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
James,Apr 2025
LAX - SFO
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
James,Apr 2025
LAX - SFO
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
James,Apr 2025
LAX - SFO
Related info for your journey
Find useful and relevant information for your journey from San Diego to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from San Diego to Knoxville
Discover the top 5 airlines that operate flights from San Diego to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$84 | Average$260 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$228 | Average$419 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$273 | Average$460 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$389 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$378 | Average$798 | FlexibilityNo cancel fee | On-time75% |