$127+ Cheap flights from San Diego to Knoxville (SAN - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from San Diego to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Knoxville McGhee Tyson are usually found in January or April, booked 21 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday
Cheap flight deals from San Diego to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $258 (Frontier) |
One-way from | $127 (CheapOair) |
Popular in | December |
Cheapest in | January |
Average price | $379 |
Find flight deals from San Diego to Knoxville
Cheapest flights from San Diego to KnoxvilleExplore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.
Explore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Alaska Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from San Diego to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Thu 6/5
6:25 am-4:29 pm
1 stop7h 04m
Knoxville McGhee Tyson
Sun 6/8
5:25 pm-11:55 pm
1 stop9h 30m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 6/17
10:15 pm-10:19 am
1 stop9h 04m
Knoxville McGhee Tyson
Tue 7/8
6:42 am-10:57 am
1 stop7h 15m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 5/27
9:45 pm-8:24 am
1 stop7h 39m
Knoxville McGhee Tyson
Tue 6/3
2:54 pm-6:56 pm
1 stop7h 02m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Wed 6/11
8:08 am-8:19 am
2 stops21h 11m
Knoxville McGhee Tyson
Sun 6/15
5:59 pm-6:26 pm
2 stops27h 27m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 5/13
10:30 am-10:24 pm
2 stops8h 54m
Knoxville McGhee Tyson
Sat 5/17
7:00 am-11:43 am
1 stop7h 43m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 5/16
3:45 pm-11:41 am
2 stops16h 56m
Knoxville McGhee Tyson
Mon 5/19
2:56 pm-8:46 pm
1 stop8h 50m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 5/31
6:18 pm-4:29 pm
1 stop19h 11m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Thu 5/29
8:30 pm-10:27 am
2 stops10h 57m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Wed 6/11
8:08 am-8:19 am
2 stops21h 11m
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 5/13
6:15 am-3:17 pm
1 stop6h 02m
Compare providers for flights from San Diego to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Knoxville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Diego-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Diego with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Knoxville
How far ahead should I book a flight from San Diego to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Knoxville. Price data was last updated on April 25, 2025.
Booking 21 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Knoxville?
Currently, January is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $296). Flying from San Diego to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to TYS?
Find hourly flight availability from San Diego to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.
It’s typically best to fly out from San Diego to Knoxville at noon. Doing so could potentially save you 22% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from San Diego to Knoxville?
Use this chart to determine the cheapest time to fly round-trip from San Diego to Knoxville. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their San Diego to Knoxville flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Rainfall in Knoxville by month
Plan your trip to Knoxville by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.
Temperature in Knoxville by month
Plan your trip to Knoxville by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 29, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta and United Airlines from San Diego to Knoxville by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
Entertainment
Food
Boarding
Crew
Comfort
Reviews
James,Apr 2025
LAX - SFO
Overall
Entertainment
Food
Boarding
Crew
Comfort
Reviews
James,Apr 2025
LAX - SFO
Overall
Entertainment
Food
Boarding
Crew
Comfort
Reviews
James,Apr 2025
LAX - SFO
Overall
Entertainment
Food
Boarding
Crew
Comfort
Reviews
James,Apr 2025
LAX - SFO
Overall
Entertainment
Food
Boarding
Crew
Comfort
Reviews
James,Apr 2025
LAX - SFO
Overall
Entertainment
Food
Boarding
Crew
Comfort
Reviews
James,Apr 2025
LAX - SFO
Related info for your journey
Find useful and relevant information for your journey from San Diego to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from San Diego to Knoxville
Discover the top 5 airlines that operate flights from San Diego to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$84 | Average$260 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$228 | Average$424 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$264 | Average$457 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$392 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$378 | Average$798 | FlexibilityNo cancel fee | On-time75% |