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Knoxville

$133+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:00 am
BOI
-
TYS
1 stop6h 37m
American Airlines
Wed 3/184:29 pm
TYS
-
BOI
1 stop7h 54m
American Airlines
Deal found 1/28$359
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:10 am
PDX
-
TYS
1 stop8h 00m
United Airlines
Tue 3/102:21 pm
TYS
-
PDX
1 stop10h 37m
United Airlines
Deal found 1/28$359
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:59 pm
PDX
-
TYS
1 stop7h 13m
United Airlines
Sat 2/286:45 am
TYS
-
PDX
1 stop8h 10m
United Airlines
Deal found 1/29$363
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:07 pm
RDM
-
TYS
1 stop6h 13m
United Airlines
Tue 8/259:15 am
TYS
-
RDM
2 stops11h 48m
United Airlines
Deal found 1/28$364
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:35 pm
PDX
-
TYS
2 stops9h 22m
American Airlines
Tue 3/1012:21 pm
TYS
-
PDX
2 stops11h 46m
American Airlines
Deal found 1/28$370
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:40 pm
PDX
-
TYS
1 stop9h 50m
American Airlines
Tue 4/217:33 pm
TYS
-
PDX
1 stop7h 08m
American Airlines
Deal found 1/27$372
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:20 am
PDX
-
TYS
2 stops10h 52m
Delta
Sat 2/281:30 pm
TYS
-
PDX
2 stops12h 18m
Delta
Deal found 1/29$374
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:40 am
BOI
-
TYS
2 stops12h 25m
Southwest
Wed 4/227:05 am
TYS
-
BOI
2 stops10h 20m
Southwest
Deal found 1/26$375
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/183:08 pm
PDX
-
TYS
1 stop16h 48m
American Airlines
Sat 4/257:50 am
TYS
-
PDX
1 stop17h 42m
American Airlines
Deal found 1/27$375
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:15 pm
PDX
-
TYS
1 stop8h 06m
Delta
Tue 4/2112:03 pm
TYS
-
PDX
2 stops11h 02m
Delta
Deal found 1/28$377
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:30 am
PDX
-
TYS
2 stops13h 12m
Delta
Sat 5/27:50 am
TYS
-
PDX
2 stops12h 42m
Delta
Deal found 1/28$383
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:59 pm
PDX
-
TYS
1 stop7h 57m
American Airlines
Sat 5/23:58 pm
TYS
-
PDX
1 stop8h 01m
American Airlines
Deal found 1/27$385

Find flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(American Airlines)

One-way from

$133
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$414
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($19 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Oregon

Fly to

Knoxville

Route

Depart

Return

Price

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 2/25

11:59 pm-10:12 am

1 stop7h 13m

Knoxville McGhee Tyson

Sat 2/28

6:45 am-11:55 am

1 stop8h 10m

$363

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 3/3

5:05 am-3:05 pm

1 stop7h 00m

Knoxville McGhee Tyson

Tue 3/10

7:00 am-1:44 pm

2 stops9h 44m

$364

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 2/25

6:00 am-8:55 pm

2 stops11h 55m

Knoxville McGhee Tyson

Sat 2/28

5:35 am-10:52 am

1 stop8h 17m

$368

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 4/28

7:00 am-6:04 pm

1 stop8h 04m

Knoxville McGhee Tyson

Sat 5/2

5:06 pm-11:41 pm

1 stop9h 35m

$372

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Tue 3/24

5:40 am-8:05 pm

2 stops12h 25m

Knoxville McGhee Tyson

Wed 4/22

7:05 am-3:25 pm

2 stops10h 20m

$375

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 4/28

11:15 pm-10:21 am

1 stop8h 06m

Knoxville McGhee Tyson

Sat 5/2

7:50 am-5:32 pm

2 stops12h 42m

$377

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Tue 3/24

6:15 am-3:02 pm

1 stop6h 47m

Knoxville McGhee Tyson

Wed 4/22

4:30 pm-9:22 pm

1 stop6h 52m

$385

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Tue 3/10

6:33 pm-8:42 am

2 stops12h 09m

Knoxville McGhee Tyson

Wed 3/18

5:40 am-12:48 pm

1 stop9h 08m

$390

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sat 4/18

1:55 pm-11:56 pm

1 stop7h 01m

Knoxville McGhee Tyson

Sat 4/25

3:58 pm-10:32 pm

2 stops9h 34m

$390

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Tue 6/30

11:30 pm-9:11 am

1 stop7h 41m

Knoxville McGhee Tyson

Tue 7/7

6:15 pm-11:56 pm

2 stops7h 41m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 49 results
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Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 7h 13m. Airlines will cover a distance of 2107 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $107 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $124 and $124, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Bend/Redmond - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$240Average$326FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$248Average$565FlexibilityNo cancel feeOn-time69%
DeltaCheapest$278Average$428FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$293Average$482FlexibilityNo cancel feeOn-time71%

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