HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$219+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Oregon to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:52 pmPDX - TYS
1 stop9h 04mUnited Airlines
Wed 1/74:55 pmTYS - PDX
1 stop8h 58mUnited Airlines
Deal found 12/9$434
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:47 pmPDX - TYS
1 stop28h 52mMultiple Airlines
Tue 1/65:37 pmTYS - PDX
2 stops44h 38mMultiple Airlines
Deal found 12/7$441
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:14 amPDX - TYS
1 stop8h 08mMultiple Airlines
Sun 1/1110:00 amTYS - PDX
2 stops26h 34mMultiple Airlines
Deal found 12/9$470
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:52 pmPDX - TYS
1 stop9h 04mUnited Airlines
Mon 1/121:59 pmTYS - PDX
2 stops10h 13mUnited Airlines
Deal found 12/7$491
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:54 pmBOI - TYS
1 stop24h 37mMultiple Airlines
Sun 1/46:30 amTYS - BOI
1 stop7h 13mMultiple Airlines
Deal found 12/8$496
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:52 pmPDX - TYS
1 stop9h 04mUnited Airlines
Mon 1/55:35 pmTYS - PDX
1 stop8h 05mUnited Airlines
Deal found 12/9$499
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:59 pmPDX - TYS
1 stop26h 32mMultiple Airlines
Tue 1/65:37 pmTYS - PDX
2 stops44h 38mMultiple Airlines
Deal found 12/7$502
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:47 pmPDX - TYS
1 stop28h 52mMultiple Airlines
Sun 1/46:30 amTYS - PDX
1 stop8h 13mMultiple Airlines
Deal found 12/7$505
This Delta deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:35 pmPDX - TYS
1 stop18h 56mDelta
Wed 1/76:30 amTYS - PDX
1 stop9h 16mDelta
Deal found 12/7$517
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:38 pmBOI - TYS
1 stop25h 13mMultiple Airlines
Sun 1/46:30 amTYS - BOI
1 stop7h 13mMultiple Airlines
Deal found 12/8$548
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:35 amBOI - TYS
2 stops11h 17mDelta
Sat 12/1310:46 amTYS - BOI
2 stops10h 48mDelta
Deal found 12/9$574
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:54 pmBOI - TYS
1 stop24h 37mMultiple Airlines
Sat 1/312:21 pmTYS - BOI
2 stops30h 31mMultiple Airlines
Deal found 12/8$638

Find flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$351
(United Airlines)

One-way from

$219
(American Airlines)

Popular in

March

Cheapest in

February

Average price

$559
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Oregon

Fly to

Knoxville

Route

Depart

Return

Price

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Sat 1/24

1:16 pm-10:31 pm

1 stop6h 15m

Knoxville McGhee Tyson

Tue 1/27

4:25 pm-9:21 pm

1 stop7h 56m

$351

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sat 1/24

10:47 am-8:52 pm

1 stop7h 05m

Knoxville McGhee Tyson

Wed 1/28

4:25 pm-9:12 pm

1 stop7h 47m

$367

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 1/6

7:37 pm-12:13 pm

2 stops13h 36m

Knoxville McGhee Tyson

Tue 1/13

5:40 am-12:32 pm

2 stops9h 52m

$377

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 1/15

12:35 pm-10:47 pm

1 stop7h 12m

Knoxville McGhee Tyson

Wed 1/21

4:41 pm-10:17 pm

1 stop8h 36m

$399

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Sat 5/2

12:56 pm-10:23 pm

1 stop6h 27m

Knoxville McGhee Tyson

Tue 5/5

4:25 pm-9:09 pm

1 stop7h 44m

$409

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 2/25

11:59 pm-11:27 am

1 stop8h 28m

Knoxville McGhee Tyson

Sun 3/1

12:20 pm-6:09 pm

1 stop8h 49m

$410

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Wed 1/21

3:03 pm-11:09 pm

1 stop6h 06m

Knoxville McGhee Tyson

Fri 1/30

6:30 am-1:34 pm

1 stop9h 04m

$413

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 1/29

6:00 am-10:09 pm

1 stop13h 09m

Knoxville McGhee Tyson

Sun 2/1

7:54 am-8:22 pm

1 stop15h 28m

$415

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 1/30

6:00 am-10:09 pm

1 stop13h 09m

Knoxville McGhee Tyson

Sun 2/1

7:54 am-8:22 pm

1 stop15h 28m

$415

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Wed 1/28

5:00 am-7:27 pm

2 stops11h 27m

Knoxville McGhee Tyson

Sat 1/31

11:40 am-9:02 pm

2 stops12h 22m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 26 results
1
2
3

Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OR to TYS?

Find hourly flight availability from Oregon to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 9, 2025.

One of the essential ways to save on airfare from Oregon to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 37% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 6h 15m. Airlines will cover a distance of 2030 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $107 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $124 and $124, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Eugene - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Oregon to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Nashville flights
Los Angeles to Nashville flights
Newark to Nashville flights
LaGuardia to Nashville flights
Boston to Nashville flights
O'Hare Intl to Nashville flights
Reagan-National to Nashville flights
LaGuardia to Memphis flights
John F Kennedy Intl to Memphis flights
Hobby to Nashville flights
Dallas/Fort Worth to Nashville flights
Baltimore to Nashville flights
Seattle to Nashville flights
Philadelphia to Nashville flights
Denver to Nashville flights
Dulles Intl to Nashville flights
Newark to Memphis flights
San Francisco to Nashville flights
Baltimore to Memphis flights
Reagan-National to Memphis flights
George Bush Intcntl to Nashville flights
Orlando to Nashville flights
Dulles Intl to Memphis flights
Sky Harbor Intl to Nashville flights
Fort Lauderdale to Nashville flights
Los Angeles to Memphis flights
Minneapolis to Nashville flights
Ontario to Nashville flights
Detroit to Nashville flights
Raleigh to Nashville flights
Miami to Nashville flights
Tampa to Nashville flights
Santa Ana to Nashville flights
San Diego to Nashville flights
Cleveland to Nashville flights
Denver to Memphis flights
Midway to Nashville flights
Atlanta to Memphis flights
Hartford to Nashville flights
O'Hare Intl to Knoxville flights
LaGuardia to Knoxville flights
Hobby to Memphis flights
Boston to Memphis flights
Richmond to Nashville flights
Dallas/Fort Worth to Knoxville flights
Bozeman to Nashville flights
George Bush Intcntl to Memphis flights
Burbank to Nashville flights
Jacksonville to Nashville flights
John F Kennedy Intl to Knoxville flights

Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$240Average$290FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$258Average$579FlexibilityNo cancel feeOn-time69%
DeltaCheapest$278Average$442FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$293Average$479FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.