HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$160+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Jul 29 — Aug 51
Wed 7/29
Wed 8/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Oregon to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.

This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:12 pm
BOI
-
TYS
1 stop9h 06m
American Airlines
Thu 8/276:03 am
TYS
-
BOI
1 stop7h 13m
American Airlines
Deal found 6/26$307
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:19 pm
EUG
-
TYS
1 stop8h 04m
United Airlines
Sat 9/196:00 am
TYS
-
EUG
1 stop8h 50m
United Airlines
Deal found 6/26$309
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:40 am
EUG
-
TYS
1 stop6h 15m
Southwest
Sat 9/191:55 pm
TYS
-
EUG
1 stop10h 20m
Southwest
Deal found 6/26$317
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:25 pm
EUG
-
TYS
2 stops20h 35m
Southwest
Wed 9/93:00 pm
TYS
-
EUG
1 stop10h 30m
Southwest
Deal found 6/26$331
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:25 pm
EUG
-
TYS
2 stops20h 35m
Southwest
Tue 8/113:00 pm
TYS
-
EUG
1 stop10h 30m
Southwest
Deal found 6/25$334
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:51 pm
EUG
-
TYS
2 stops13h 23m
Delta
Sat 10/313:55 pm
TYS
-
EUG
2 stops10h 52m
Delta
Deal found 6/26$335
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:59 pm
BOI
-
TYS
1 stop7h 53m
Delta
Tue 8/256:25 pm
TYS
-
BOI
1 stop7h 34m
Delta
Deal found 6/25$337
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:56 pm
PDX
-
TYS
1 stop16h 53m
Multiple Airlines
Sun 8/237:00 am
TYS
-
PDX
1 stop13h 11m
Multiple Airlines
Deal found 6/28$339
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:49 pm
BOI
-
TYS
1 stop6h 29m
American Airlines
Tue 8/256:03 am
TYS
-
BOI
2 stops9h 21m
American Airlines
Deal found 6/25$342
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:25 pm
EUG
-
TYS
2 stops20h 40m
Southwest
Sat 9/191:55 pm
TYS
-
EUG
1 stop10h 20m
Southwest
Deal found 6/26$347
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:45 pm
EUG
-
TYS
2 stops13h 27m
Delta
Mon 10/2611:30 am
TYS
-
EUG
2 stops15h 17m
Delta
Deal found 6/26$351
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
PDX
-
TYS
1 stop7h 42m
American Airlines
Tue 9/225:35 pm
TYS
-
PDX
1 stop8h 48m
American Airlines
Deal found 6/29$355

Find flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated June 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$307
(American Airlines)

One-way from

$160
(Delta)

Popular in

May

Cheapest in

October

Average price

$516
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Wed 8/19

8:01 am-11:18 pm

2 stops13h 17m

Knoxville McGhee Tyson

Thu 8/27

1:56 pm-10:40 pm

2 stops10h 44m

$317

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Mon 8/17

1:59 pm-11:52 pm

1 stop7h 53m

Knoxville McGhee Tyson

Tue 8/25

6:25 pm-11:59 pm

1 stop7h 34m

$337

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 9/22

10:50 am-12:23 am

2 stops10h 33m

Knoxville McGhee Tyson

Thu 9/24

4:53 pm-9:10 pm

1 stop7h 17m

$370

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 9/30

6:45 am-4:30 pm

1 stop6h 45m

Knoxville McGhee Tyson

Mon 10/5

5:25 pm-12:45 am

2 stops10h 20m

$371

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Wed 9/16

6:00 am-6:55 pm

2 stops10h 55m

Knoxville McGhee Tyson

Wed 9/23

1:55 pm-11:10 pm

2 stops11h 15m

$373

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Mon 8/17

2:49 pm-11:18 pm

1 stop6h 29m

Knoxville McGhee Tyson

Tue 8/25

6:03 am-1:24 pm

2 stops9h 21m

$373

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 8/5

11:59 pm-11:19 am

1 stop8h 20m

Knoxville McGhee Tyson

Sat 8/29

6:02 pm-10:52 pm

1 stop7h 50m

$376

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Mon 9/14

6:40 am-3:55 pm

1 stop6h 15m

Knoxville McGhee Tyson

Sat 9/19

1:55 pm-9:15 pm

1 stop10h 20m

$376

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Mon 8/17

6:00 am-6:35 pm

2 stops10h 35m

Knoxville McGhee Tyson

Tue 8/25

7:00 am-1:40 pm

2 stops8h 40m

$384

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Wed 9/2

6:40 am-4:30 pm

1 stop6h 50m

Knoxville McGhee Tyson

Wed 9/9

3:00 pm-10:30 pm

1 stop10h 30m

$385

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/28

Showing 1-10 of 47 resultsSorted by cheapest first
1
2
3
...
5

Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $139). Flying from Oregon to Knoxville in June is currently the most expensive (average of $374). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Oregon to Knoxville?

How far ahead should I book a flight from Oregon to Knoxville?

To ensure you get the cheapest price possible for a flight from Oregon to Knoxville, you should look to book at least 74 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 7h 53m. Airlines will cover a distance of 1782 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $125 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $134 and $218, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Eugene - Knoxville McGhee Tyson and Boise Air Term. Gowen Fld - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $139). Flying from Oregon to Knoxville in June is currently the most expensive (average of $374). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Oregon to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Nashville flights
Los Angeles to Nashville flights
John F Kennedy Intl to Nashville flights
LaGuardia to Nashville flights
Boston to Nashville flights
Philadelphia to Nashville flights
Reagan-National to Nashville flights
Seattle to Nashville flights
O'Hare Intl to Nashville flights
Baltimore to Nashville flights
Dallas/Fort Worth to Nashville flights
Denver to Nashville flights
Dulles Intl to Nashville flights
San Francisco to Nashville flights
Tampa to Nashville flights
Raleigh to Nashville flights
Hobby to Nashville flights
Sky Harbor Intl to Nashville flights
Orlando to Nashville flights
George Bush Intcntl to Nashville flights
Minneapolis to Nashville flights
Austin to Nashville flights
Ontario to Nashville flights
Cleveland to Nashville flights
Detroit to Nashville flights
LaGuardia to Knoxville flights
Dallas/Fort Worth to Knoxville flights
Miami to Nashville flights
Hartford to Nashville flights
San Diego to Nashville flights
Charlotte to Nashville flights
Portland to Nashville flights
LaGuardia to Memphis flights
George Bush Intcntl to Knoxville flights
O'Hare Intl to Knoxville flights
John F Kennedy Intl to Knoxville flights
Sacramento to Nashville flights
Newark to Memphis flights
Burbank to Nashville flights
Fort Lauderdale to Nashville flights
Hobby to Knoxville flights
Denver to Knoxville flights
West Palm Beach to Nashville flights
New Orleans to Nashville flights
San Jose to Nashville flights
Love Field to Nashville flights
Las Vegas to Nashville flights
Minneapolis to Knoxville flights
Dallas/Fort Worth to Memphis flights
O'Hare Intl to Memphis flights

Top 3 airlines flying from Oregon to Knoxville

Discover the top 3 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$268Average$497FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$304Average$466FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$317Average$567FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.