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$180+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This United Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:00 amRDM - TYS
1 stop7h 00mUnited Airlines
Wed 12/315:45 amTYS - RDM
2 stops10h 13mUnited Airlines
Deal found 12/23$549
This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:16 pmPDX - TYS
1 stop7h 57mDelta
Tue 1/65:40 amTYS - PDX
1 stop7h 54mDelta
Deal found 12/22$683
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:15 amPDX - TYS
2 stops9h 45mAmerican Airlines
Tue 1/64:41 pmTYS - PDX
1 stop8h 30mAmerican Airlines
Deal found 12/21$691
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:25 amEUG - TYS
2 stops9h 05mAmerican Airlines
Mon 12/291:24 pmTYS - EUG
2 stops12h 56mAmerican Airlines
Deal found 12/22$702
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/261:40 pmPDX - TYS
1 stop7h 05mAmerican Airlines
Tue 12/306:20 pmTYS - PDX
1 stop7h 46mAmerican Airlines
Deal found 12/22$772
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:55 pmPDX - TYS
1 stop7h 22mUnited Airlines
Tue 1/61:59 pmTYS - PDX
1 stop7h 57mUnited Airlines
Deal found 12/22$810
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:10 pmEUG - TYS
1 stop6h 19mUnited Airlines
Mon 12/295:45 amTYS - EUG
2 stops18h 28mUnited Airlines
Deal found 12/22$852
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:15 amPDX - TYS
2 stops11h 17mDelta
Sat 12/276:25 amTYS - PDX
2 stops12h 51mDelta
Deal found 12/21$929
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:47 pmPDX - TYS
1 stop28h 52mMultiple Airlines
Sat 12/278:00 amTYS - PDX
2 stops30h 43mMultiple Airlines
Deal found 12/21$976
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:59 pmPDX - TYS
1 stop8h 12mUnited Airlines
Sat 12/277:00 amTYS - PDX
1 stop9h 22mUnited Airlines
Deal found 12/21$1,062

Find flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$339
(American Airlines)

One-way from

$180
(Delta)

Popular in

March

Cheapest in

February

Average price

$559
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Oregon

Fly to

Knoxville

Route

Depart

Return

Price

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Sat 5/2

7:09 am-11:47 pm

2 stops13h 38m

Knoxville McGhee Tyson

Tue 5/5

12:18 pm-10:53 pm

2 stops13h 35m

$339

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Sat 1/31

1:16 pm-10:31 pm

1 stop6h 15m

Knoxville McGhee Tyson

Tue 2/3

4:25 pm-9:21 pm

1 stop7h 56m

$351

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Thu 1/29

7:20 am-3:46 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sat 2/7

7:44 am-7:25 pm

2 stops13h 41m

$364

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Sat 5/16

1:42 pm-11:47 pm

1 stop8h 05m

Knoxville McGhee Tyson

Sat 5/23

4:29 pm-11:05 pm

1 stop8h 36m

$389

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 2/26

1:51 pm-11:50 pm

1 stop6h 59m

Knoxville McGhee Tyson

Mon 3/2

4:30 pm-12:16 am

2 stops10h 46m

$397

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 2/27

12:57 pm-11:44 pm

1 stop7h 47m

Knoxville McGhee Tyson

Tue 3/3

7:05 am-12:22 pm

1 stop8h 17m

$398

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 2/25

6:43 am-5:33 pm

1 stop7h 50m

Knoxville McGhee Tyson

Sun 3/1

12:20 pm-6:09 pm

1 stop8h 49m

$398

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sun 1/11

11:01 pm-4:54 pm

1 stop14h 53m

Knoxville McGhee Tyson

Sat 1/17

12:15 pm-7:51 pm

2 stops10h 36m

$404

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 2/27

7:35 pm-12:08 pm

2 stops13h 33m

Knoxville McGhee Tyson

Tue 3/3

1:00 pm-8:55 pm

2 stops10h 55m

$408

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 1/29

7:38 am-5:42 pm

1 stop7h 04m

Knoxville McGhee Tyson

Sun 2/1

4:41 pm-10:11 pm

1 stop8h 30m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 38 results
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Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OR to TYS?

Find hourly flight availability from Oregon to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

One of the essential ways to save on airfare from Oregon to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 37% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 6h 15m. Airlines will cover a distance of 2030 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $107 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $124 and $124, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Eugene - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$240Average$290FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$278Average$582FlexibilityNo cancel feeOn-time69%
DeltaCheapest$279Average$454FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$293Average$480FlexibilityNo cancel feeOn-time71%

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