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Knoxville

$131+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
May 19 — May 261
Tue 5/19
Tue 5/26
1 adult, Economy
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Cheap flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 pm
PDX
-
TYS
1 stop23h 17m
Frontier
Fri 6/198:32 pm
TYS
-
PDX
1 stop23h 25m
Frontier
Deal found 4/14$270
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 pm
PDX
-
TYS
1 stop23h 17m
Multiple Airlines
Mon 6/226:30 am
TYS
-
PDX
2 stops37h 05m
Multiple Airlines
Deal found 4/14$284
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 pm
PDX
-
TYS
1 stop23h 17m
Frontier
Mon 6/228:32 pm
TYS
-
PDX
1 stop23h 03m
Frontier
Deal found 4/14$289
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:35 pm
PDX
-
TYS
2 stops31h 05m
Multiple Airlines
Fri 6/198:32 pm
TYS
-
PDX
1 stop23h 25m
Multiple Airlines
Deal found 4/14$316
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 pm
PDX
-
TYS
1 stop23h 17m
Multiple Airlines
Thu 6/182:42 pm
TYS
-
PDX
2 stops47h 59m
Multiple Airlines
Deal found 4/14$325
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:35 pm
PDX
-
TYS
2 stops31h 05m
Multiple Airlines
Mon 6/228:32 pm
TYS
-
PDX
1 stop23h 03m
Multiple Airlines
Deal found 4/14$335
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 pm
PDX
-
TYS
1 stop23h 17m
Multiple Airlines
Sun 6/217:00 am
TYS
-
PDX
1 stop12h 57m
Multiple Airlines
Deal found 4/14$346
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:30 am
RDM
-
TYS
1 stop6h 06m
United Airlines
Wed 10/287:00 am
TYS
-
RDM
2 stops11h 07m
United Airlines
Deal found 4/15$362
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:06 pm
PDX
-
TYS
2 stops25h 21m
Multiple Airlines
Fri 6/198:32 pm
TYS
-
PDX
1 stop23h 25m
Multiple Airlines
Deal found 4/14$367
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:15 am
PDX
-
TYS
2 stops25h 40m
Multiple Airlines
Fri 6/198:32 pm
TYS
-
PDX
1 stop23h 25m
Multiple Airlines
Deal found 4/14$368
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:35 pm
PDX
-
TYS
1 stop27h 49m
Multiple Airlines
Sat 5/305:11 pm
TYS
-
PDX
2 stops23h 43m
Multiple Airlines
Deal found 4/18$370
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 pm
PDX
-
TYS
1 stop23h 17m
Multiple Airlines
Wed 6/172:19 pm
TYS
-
PDX
2 stops26h 29m
Multiple Airlines
Deal found 4/14$373

Find flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated April 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$270
(Kiwi.com)

One-way from

$131
(Booking.com)

Popular in

March

Cheapest in

August

Average price

$459
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Mon 6/29

12:38 pm-8:39 pm

1 stop6h 01m

Knoxville McGhee Tyson

Sat 7/4

6:30 am-11:32 am

1 stop7h 02m

$443

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Mon 6/1

12:33 pm-12:30 am

1 stop8h 57m

Knoxville McGhee Tyson

Sat 6/6

6:30 am-11:37 am

1 stop8h 07m

$443

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Mon 6/29

10:25 am-7:10 pm

1 stop6h 45m

Knoxville McGhee Tyson

Sat 7/4

7:00 am-2:45 pm

2 stops9h 45m

$458

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Fri 6/26

8:45 am-9:10 pm

2 stops10h 25m

Knoxville McGhee Tyson

Sat 7/4

7:00 am-2:45 pm

2 stops9h 45m

$463

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Tue 6/9

10:40 am-8:20 pm

2 stops7h 40m

Knoxville McGhee Tyson

Tue 6/16

2:45 pm-10:55 pm

2 stops10h 10m

$463

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Wed 5/6

5:00 am-3:07 pm

1 stop7h 07m

Knoxville McGhee Tyson

Sat 5/9

9:50 am-9:31 pm

2 stops14h 41m

$465

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Thu 10/15

6:45 pm-3:20 pm

2 stops17h 35m

Knoxville McGhee Tyson

Mon 10/19

5:25 pm-10:45 pm

1 stop8h 20m

$473

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Sun 9/20

11:30 pm-9:11 am

1 stop7h 41m

Knoxville McGhee Tyson

Thu 9/24

6:15 pm-11:29 pm

1 stop7h 14m

$477

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Thu 9/17

11:30 pm-9:11 am

1 stop7h 41m

Knoxville McGhee Tyson

Fri 9/25

6:45 am-2:03 pm

1 stop9h 18m

$486

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Fri 9/4

6:26 pm-11:17 am

2 stops13h 51m

Knoxville McGhee Tyson

Sat 9/12

8:48 am-1:00 pm

1 stop7h 12m

$486

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/18

Showing 1-10 of 55 resultsSorted by cheapest first
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Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $139). Flying from Oregon to Knoxville in January is currently the most expensive (average of $324). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Oregon to Knoxville?

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 6h 01m. Airlines will cover a distance of 1782 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $107 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $124 and $125, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Eugene - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $139). Flying from Oregon to Knoxville in January is currently the most expensive (average of $324). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$256Average$429FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$264Average$343FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$279Average$533FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$304Average$485FlexibilityNo cancel feeOn-time71%

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