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$131+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated September 16, 2025.

Round-trip from

$247
(Kiwi.com)

One-way from

$131
(American Airlines)

Popular in

December

Cheapest in

February

Average price

$419
From Oregon to Knoxville McGhee Tyson
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One-way flight from Oregon to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 7% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:45 amPDX - TYS
1 stop7h 37mMultiple Airlines
Sun 12/146:30 amTYS - PDX
1 stop8h 27mMultiple Airlines
Deal found 9/14$247
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:07 pmPDX - TYS
1 stop19h 57mMultiple Airlines
Thu 10/235:34 pmTYS - PDX
2 stops21h 14mMultiple Airlines
Deal found 9/14$266
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:15 pmPDX - TYS
1 stop7h 19mAmerican Airlines
Tue 11/1112:46 pmTYS - PDX
1 stop10h 32mAmerican Airlines
Deal found 9/14$269
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:15 pmPDX - TYS
1 stop9h 48mDelta
Tue 11/185:25 amTYS - PDX
2 stops10h 23mDelta
Deal found 9/16$274
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:07 pmPDX - TYS
1 stop19h 57mMultiple Airlines
Fri 10/248:17 pmTYS - PDX
1 stop18h 31mMultiple Airlines
Deal found 9/14$286
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:15 amPDX - TYS
1 stop27h 18mMultiple Airlines
Sun 10/55:44 pmTYS - PDX
2 stops45h 04mMultiple Airlines
Deal found 9/16$291
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1811:59 pmPDX - TYS
1 stop8h 45mAmerican Airlines
Wed 10/226:43 pmTYS - PDX
1 stop7h 46mAmerican Airlines
Deal found 9/15$294
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1510:10 pmPDX - TYS
1 stop8h 27mDelta
Wed 11/193:51 pmTYS - PDX
1 stop9h 30mDelta
Deal found 9/16$299
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:20 amMFR - TYS
2 stops11h 23mAmerican Airlines
Tue 12/1612:46 pmTYS - MFR
2 stops10h 25mAmerican Airlines
Deal found 9/14$319
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:18 pmRDM - TYS
1 stop6h 12mUnited Airlines
Tue 12/1610:50 amTYS - RDM
2 stops13h 30mUnited Airlines
Deal found 9/14$336
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:33 pmBOI - TYS
2 stops27h 19mMultiple Airlines
Sun 11/167:00 amTYS - BOI
1 stop6h 43mMultiple Airlines
Deal found 9/15$349
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:00 amRDM - TYS
2 stops11h 58mAmerican Airlines
Tue 12/1612:46 pmTYS - RDM
2 stops9h 47mAmerican Airlines
Deal found 9/14$375

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Oregon

Fly to

Knoxville

Route

Depart

Return

Price

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 11/18

5:30 am-8:00 pm

2 stops11h 30m

Knoxville McGhee Tyson

Wed 11/19

5:25 am-12:48 pm

2 stops10h 23m

$279

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 10/17

10:58 pm-11:04 am

1 stop9h 06m

Knoxville McGhee Tyson

Wed 10/22

5:44 am-10:16 am

1 stop7h 32m

$299

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sat 11/15

10:10 pm-9:37 am

1 stop8h 27m

Knoxville McGhee Tyson

Sat 11/22

3:51 pm-10:21 pm

1 stop9h 30m

$299

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sat 11/15

10:10 pm-9:37 am

1 stop8h 27m

Knoxville McGhee Tyson

Thu 11/20

3:51 pm-10:21 pm

1 stop9h 30m

$299

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 11/19

5:30 am-7:00 pm

2 stops10h 30m

Knoxville McGhee Tyson

Sat 11/22

3:51 pm-10:21 pm

1 stop9h 30m

$304

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 11/14

11:15 pm-12:23 pm

2 stops10h 08m

Knoxville McGhee Tyson

Tue 11/18

6:29 am-12:48 pm

1 stop9h 19m

$304

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Sat 12/6

5:20 am-7:43 pm

2 stops11h 23m

Knoxville McGhee Tyson

Tue 12/16

12:46 pm-8:11 pm

2 stops10h 25m

$319

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 10/13

10:58 pm-11:04 am

1 stop9h 06m

Knoxville McGhee Tyson

Wed 10/22

5:44 am-10:16 am

1 stop7h 32m

$329

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sat 11/15

10:10 pm-9:37 am

1 stop8h 27m

Knoxville McGhee Tyson

Fri 11/21

5:25 am-12:48 pm

2 stops10h 23m

$334

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 10/29

12:06 pm-10:55 pm

1 stop7h 49m

Knoxville McGhee Tyson

Wed 11/5

10:25 am-5:27 pm

2 stops10h 02m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 55 results
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Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $295). Flying from Oregon to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OR to TYS?

Find hourly flight availability from Oregon to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Oregon to Knoxville as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 6h 12m. Airlines will cover a distance of 2030 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $131 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $175 and $190, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Eugene - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $295). Flying from Oregon to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$157Average$273FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$258Average$581FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$293Average$489FlexibilityNo cancel feeOn-time71%
DeltaCheapest$308Average$471FlexibilityNo cancel feeOn-timeN/A

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