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Knoxville

$147+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Apr 28 — May 51
Tue 4/28
Tue 5/5
1 adult, Economy
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Cheap flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.

This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:52 pm
PDX
-
TYS
1 stop7h 04m
American Airlines
Wed 4/294:09 pm
TYS
-
PDX
1 stop9h 40m
American Airlines
Deal found 3/25$293
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:00 am
RDM
-
TYS
1 stop7h 06m
United Airlines
Tue 4/284:30 pm
TYS
-
RDM
1 stop7h 46m
United Airlines
Deal found 3/24$309
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:04 pm
BOI
-
TYS
1 stop28h 33m
Frontier
Mon 6/228:32 pm
TYS
-
BOI
1 stop17h 37m
Frontier
Deal found 3/26$320
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:00 am
PDX
-
TYS
1 stop7h 06m
United Airlines
Wed 4/225:15 pm
TYS
-
PDX
1 stop8h 43m
United Airlines
Deal found 3/24$324
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:25 pm
BOI
-
TYS
1 stop28h 08m
Multiple Airlines
Mon 6/15:30 pm
TYS
-
BOI
2 stops21h 00m
Multiple Airlines
Deal found 3/26$328
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:48 am
PDX
-
TYS
2 stops9h 08m
American Airlines
Wed 4/224:09 pm
TYS
-
PDX
1 stop8h 29m
American Airlines
Deal found 3/24$329
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:40 pm
PDX
-
TYS
1 stop9h 50m
American Airlines
Tue 5/124:09 pm
TYS
-
PDX
1 stop9h 41m
American Airlines
Deal found 3/24$337
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:53 pm
BOI
-
TYS
1 stop8h 03m
Delta
Fri 5/293:30 pm
TYS
-
BOI
1 stop8h 58m
Delta
Deal found 3/26$346
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:25 pm
BOI
-
TYS
1 stop28h 08m
Multiple Airlines
Mon 6/15:30 pm
TYS
-
BOI
2 stops21h 00m
Multiple Airlines
Deal found 3/26$347
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:04 pm
BOI
-
TYS
1 stop28h 33m
Multiple Airlines
Sun 8/237:00 am
TYS
-
BOI
1 stop7h 09m
Multiple Airlines
Deal found 3/25$354
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:37 pm
BOI
-
TYS
1 stop5h 52m
United Airlines
Sat 5/97:00 am
TYS
-
BOI
1 stop6h 49m
United Airlines
Deal found 3/24$355
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3112:40 am
PDX
-
TYS
1 stop9h 22m
American Airlines
Thu 6/48:11 pm
TYS
-
PDX
1 stop7h 39m
American Airlines
Deal found 3/25$355

Find flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated March 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$293
(American Airlines)

One-way from

$147
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$582
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Tue 4/21

5:00 am-3:06 pm

1 stop7h 06m

Knoxville McGhee Tyson

Tue 4/28

4:30 pm-9:16 pm

1 stop7h 46m

$309

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 4/21

7:00 am-7:56 pm

1 stop9h 56m

Knoxville McGhee Tyson

Wed 4/22

5:15 pm-10:58 pm

1 stop8h 43m

$403

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Sat 5/2

12:52 pm-10:23 pm

1 stop6h 31m

Knoxville McGhee Tyson

Wed 5/6

7:00 am-12:00 pm

1 stop8h 00m

$423

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Wed 4/8

1:40 pm-11:57 pm

1 stop8h 17m

Knoxville McGhee Tyson

Wed 4/15

5:40 am-2:26 pm

2 stops10h 46m

$424

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 4/8

11:40 am-11:57 pm

1 stop9h 17m

Knoxville McGhee Tyson

Wed 4/15

5:40 am-10:41 am

1 stop8h 01m

$435

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Sat 5/2

8:38 pm-10:26 am

2 stops10h 48m

Knoxville McGhee Tyson

Wed 5/6

10:56 am-10:54 pm

2 stops14h 58m

$439

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 5/28

10:40 pm-2:27 pm

2 stops12h 47m

Knoxville McGhee Tyson

Wed 6/3

5:57 pm-11:53 pm

1 stop8h 56m

$439

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Sun 5/24

5:00 am-5:12 pm

2 stops9h 12m

Knoxville McGhee Tyson

Sat 5/30

6:30 am-11:37 am

1 stop8h 07m

$442
Quickest round-trip

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Sat 5/2

12:55 pm-10:23 pm

1 stop6h 28m

Knoxville McGhee Tyson

Tue 5/5

8:45 am-12:55 pm

1 stop7h 10m

$444

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 4/24

10:50 am-10:34 pm

1 stop8h 44m

Knoxville McGhee Tyson

Tue 4/28

7:00 am-1:08 pm

2 stops9h 08m

$457

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 49 resultsSorted by cheapest first
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Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $126). Flying from Oregon to Knoxville in May is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Oregon to Knoxville?

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 7h 06m. Airlines will cover a distance of 2030 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $107 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $124 and $124, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Medford - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $126). Flying from Oregon to Knoxville in May is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Alternative routes for Oregon to Knoxville

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Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$240Average$326FlexibilityNo cancel feeOn-time62%
DeltaCheapest$256Average$428FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$279Average$543FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$298Average$481FlexibilityNo cancel feeOn-time71%

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