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Knoxville

$135+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
nov. 26 — dic. 31
mié. 11/26
mié. 12/3
1 adult, Economy
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Find flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/210:15 pmPDX - TYS
1 stop8h 39mAmerican Airlines
mié. 12/35:03 pmTYS - PDX
1 stop9h 49mAmerican Airlines
Deal found 10/26$269
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/910:10 pmPDX - TYS
1 stop8h 28mDelta
sáb. 12/131:27 pmTYS - PDX
2 stops10h 25mDelta
Deal found 10/25$274
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1512:52 pmPDX - TYS
1 stop26h 30mMultiple Airlines
lun. 11/2412:33 pmTYS - PDX
2 stops23h 48mMultiple Airlines
Deal found 10/25$289
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/912:00 pmPDX - TYS
1 stop8h 59mAmerican Airlines
sáb. 12/136:18 pmTYS - PDX
1 stop8h 05mAmerican Airlines
Deal found 10/25$294
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/51:59 pmPDX - TYS
1 stop6h 19mDelta
mar. 12/92:37 pmTYS - PDX
1 stop7h 58mDelta
Deal found 10/25$299
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/412:44 pmBOI - TYS
2 stops31h 05mMultiple Airlines
vie. 12/128:00 amTYS - BOI
1 stop9h 44mMultiple Airlines
Deal found 10/25$346
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/812:52 pmPDX - TYS
1 stop21h 52mMultiple Airlines
lun. 11/108:00 amTYS - PDX
2 stops30h 56mMultiple Airlines
Deal found 10/24$375
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/165:30 amPDX - TYS
1 stop8h 58mAmerican Airlines
lun. 11/246:38 pmTYS - PDX
1 stop7h 48mAmerican Airlines
Deal found 10/25$383
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:36 pmMFR - TYS
2 stops13h 12mUnited Airlines
mié. 11/124:55 pmTYS - MFR
1 stop7h 19mUnited Airlines
Deal found 10/26$422
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/41:25 pmBOI - TYS
1 stop8h 25mAmerican Airlines
vie. 12/125:24 amTYS - BOI
1 stop9h 03mAmerican Airlines
Deal found 10/25$437
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/411:44 amBOI - TYS
2 stops9h 34mDelta
vie. 12/123:57 pmTYS - BOI
2 stops10h 12mDelta
Deal found 10/25$447
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/299:46 pmBOI - TYS
2 stops16h 05mMultiple Airlines
lun. 1/58:00 amTYS - BOI
1 stop9h 04mMultiple Airlines
Deal found 10/25$466

Cheap flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated octubre 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$135
(Delta)

Popular in

December

Cheapest in

August

Average price

$429
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 27, 2025.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Oregon

Fly to

Knoxville

Route

Depart

Return

Price

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

mar. 12/9

10:10 pm-9:38 am

1 stop8h 28m

Knoxville McGhee Tyson

sáb. 12/13

1:27 pm-8:52 pm

2 stops10h 25m

$274

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

vie. 12/5

1:59 pm-11:18 pm

1 stop6h 19m

Knoxville McGhee Tyson

mar. 12/9

2:37 pm-7:35 pm

1 stop7h 58m

$299

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

jue. 1/8

6:00 pm-9:45 am

2 stops12h 45m

Knoxville McGhee Tyson

sáb. 1/17

7:54 am-7:38 pm

2 stops14h 44m

$319

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

jue. 12/4

12:44 pm-9:49 pm

2 stops31h 05m

Knoxville McGhee Tyson

vie. 12/12

8:00 am-3:44 pm

1 stop9h 44m

$346

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

mar. 12/2

11:40 am-12:20 am

2 stops9h 40m

Knoxville McGhee Tyson

mié. 12/3

5:03 pm-11:52 pm

1 stop9h 49m

$349

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

mar. 2/24

6:05 am-9:32 pm

2 stops12h 27m

Knoxville McGhee Tyson

sáb. 2/28

6:45 am-1:03 pm

2 stops9h 18m

$364

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

jue. 1/8

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

sáb. 1/17

6:45 am-5:52 pm

2 stops14h 07m

$368

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

sáb. 11/8

12:52 pm-1:44 pm

1 stop21h 52m

Knoxville McGhee Tyson

lun. 11/10

8:00 am-11:56 am

2 stops30h 56m

$375

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

dom. 11/16

5:30 am-5:28 pm

1 stop8h 58m

Knoxville McGhee Tyson

lun. 11/24

6:38 pm-11:26 pm

1 stop7h 48m

$383

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

mar. 2/24

7:25 pm-11:47 am

2 stops13h 22m

Knoxville McGhee Tyson

sáb. 2/28

6:45 am-10:42 pm

2 stops18h 57m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Showing 1-10 of 41 results
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Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OR to TYS?

Find hourly flight availability from Oregon to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 27, 2025.

One of the essential ways to save on airfare from Oregon to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 37% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 7h 14m. Airlines will cover a distance of 2113 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $135 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $135 and $374, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Medford - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$195Average$278FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$258Average$567FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$293Average$481FlexibilityNo cancel feeOn-time71%
DeltaCheapest$298Average$460FlexibilityNo cancel feeOn-timeN/A

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