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Knoxville

$166+ Cheap flights from Oregon to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/18. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Dec 10 — Dec 171
Wed 12/10
Wed 12/17
1 adult, Economy
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Find flight deals from Oregon to Knoxville

Cheapest flights from Oregon to Knoxville
Explore the most affordable flight options available from Oregon to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2112:48 pmBOI - TYS
1 stop28h 22mMultiple Airlines
Tue 11/257:00 amTYS - BOI
1 stop6h 53mMultiple Airlines
Deal found 11/8$327
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:13 pmBOI - TYS
1 stop6h 05mDelta
Tue 12/165:40 amTYS - BOI
1 stop9h 14mDelta
Deal found 11/9$359
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/91:59 pmPDX - TYS
1 stop6h 19mDelta
Sat 12/135:36 pmTYS - PDX
1 stop7h 43mDelta
Deal found 11/8$363
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:10 amPDX - TYS
1 stop7h 39mDelta
Sat 12/137:30 amTYS - PDX
2 stops11h 50mDelta
Deal found 11/8$372
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:59 pmPDX - TYS
2 stops20h 32mMultiple Airlines
Wed 12/311:58 pmTYS - PDX
1 stop24h 45mMultiple Airlines
Deal found 11/9$378
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:47 pmPDX - TYS
2 stops30h 00mMultiple Airlines
Sun 12/216:30 amTYS - PDX
1 stop8h 13mMultiple Airlines
Deal found 11/8$409
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:00 amPDX - TYS
1 stop7h 30mAmerican Airlines
Sun 12/214:29 pmTYS - PDX
1 stop8h 30mAmerican Airlines
Deal found 11/8$411
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:13 pmBOI - TYS
1 stop6h 05mDelta
Fri 12/125:40 amTYS - BOI
2 stops10h 38mDelta
Deal found 11/10$416
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:30 amEUG - TYS
2 stops10h 33mDelta
Sat 12/133:50 pmTYS - EUG
2 stops10h 21mDelta
Deal found 11/8$440
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/222:43 pmBOI - TYS
2 stops29h 54mMultiple Airlines
Thu 12/44:52 pmTYS - BOI
1 stop20h 57mMultiple Airlines
Deal found 11/9$459
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:56 pmEUG - TYS
1 stop17h 06mMultiple Airlines
Sun 12/216:30 amTYS - EUG
2 stops16h 41mMultiple Airlines
Deal found 11/8$470
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:04 pmBOI - TYS
1 stop7h 24mDelta
Sat 12/137:33 amTYS - BOI
1 stop7h 21mDelta
Deal found 11/9$471

Cheap flight deals from Oregon to Knoxville

Keep the following information in mind while searching for Oregon to Knoxville flight deals. Data was last updated November 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$285
(United Airlines)

One-way from

$166
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$446
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
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From Oregon to Knoxville McGhee Tyson
Search Deals
One-way flight from Oregon to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($56 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Oregon to Knoxville that are best for you.

Fly from

Oregon

Fly to

Knoxville

Route

Depart

Return

Price

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Sat 2/14

7:07 pm-10:19 am

2 stops12h 12m

Knoxville McGhee Tyson

Wed 3/11

4:25 pm-9:26 pm

1 stop8h 01m

$285

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Sat 2/21

7:00 am-8:47 pm

2 stops10h 47m

Knoxville McGhee Tyson

Sat 2/28

1:30 pm-10:47 pm

2 stops12h 17m

$315

RedmondKnoxville

RDM - TYS

RDMTYS

Bend/Redmond

Tue 2/24

5:50 am-8:47 pm

2 stops11h 57m

Knoxville McGhee Tyson

Sat 2/28

1:30 pm-10:47 pm

2 stops12h 17m

$315

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Sat 2/21

6:05 am-8:47 pm

2 stops11h 42m

Knoxville McGhee Tyson

Sat 2/28

5:30 am-12:20 pm

2 stops9h 50m

$319

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Tue 2/24

5:20 pm-9:06 am

2 stops12h 46m

Knoxville McGhee Tyson

Sat 2/28

5:30 am-2:33 pm

2 stops12h 03m

$319

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Fri 11/21

12:48 pm-7:10 pm

1 stop28h 22m

Knoxville McGhee Tyson

Tue 11/25

7:00 am-11:53 am

1 stop6h 53m

$327

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 12/9

1:59 pm-11:18 pm

1 stop6h 19m

Knoxville McGhee Tyson

Sat 12/13

5:36 pm-10:19 pm

1 stop7h 43m

$363

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Tue 12/9

11:44 am-11:18 pm

2 stops9h 34m

Knoxville McGhee Tyson

Tue 12/16

5:40 am-12:54 pm

1 stop9h 14m

$364

BoiseKnoxville

BOI - TYS

BOITYS

Boise Air Term. Gowen Fld

Sat 2/28

1:41 pm-11:50 pm

1 stop8h 09m

Knoxville McGhee Tyson

Wed 3/4

5:30 am-12:31 pm

1 stop9h 01m

$372

EugeneKnoxville

EUG - TYS

EUGTYS

Eugene

Sat 1/17

6:00 am-9:02 pm

2 stops12h 02m

Knoxville McGhee Tyson

Wed 1/21

4:25 pm-9:10 pm

1 stop7h 45m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 44 results
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Best time to book a flight from Oregon to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Knoxville

What is the cheapest month to book a flight from Oregon to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OR to TYS?

Find hourly flight availability from Oregon to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 10, 2025.

One of the essential ways to save on airfare from Oregon to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 37% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Oregon?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Oregon.

  • How long is the flight from Oregon to Knoxville?

    Departing from Oregon to Knoxville will take you 10h 47m. Airlines will cover a distance of 2030 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Oregon to Knoxville one-way?

    $174 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $193 and $284, respectively.

  • What are the most popular routes from Oregon to Knoxville?

    The most popular flight routes from Oregon to Knoxville are Portland - Knoxville McGhee Tyson, Boise Air Term. Gowen Fld - Knoxville McGhee Tyson and Medford - Knoxville McGhee Tyson.

  • Can I find deals for flights from Oregon to Knoxville that include hotel bookings?

    Yes. In addition to deals on Oregon to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Knoxville.

  • Can I find deals for business class flights from Oregon to Knoxville?

    Yes. Cheapflights offers flight deals from Oregon to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Oregon to Knoxville (average of $128). Flying from Oregon to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Oregon to Knoxville

Discover the top 4 airlines that operate flights from Oregon to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$240Average$290FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$258Average$564FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$293Average$479FlexibilityNo cancel feeOn-time71%
DeltaCheapest$298Average$467FlexibilityNo cancel feeOn-timeN/A

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