$118+ Cheap flights from Minneapolis to Knoxville (MSP - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — TYS
Nov 22 — Nov 291
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Minneapolis St Paul to Knoxville McGhee Tyson are usually found in August or February, booked 16 days in advance, depart on a Saturday or Tuesday and return on a Tuesday
Cheap flight deals from Minneapolis to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Minneapolis to KnoxvilleExplore the most affordable flight options available from Minneapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
Explore the most affordable flight options available from Minneapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:55 am -
1 stop4h 05m
Thu 12/107:05 am -
1 stop4h 10m
Deal found 10/18![Southwest logo]()
$236
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:00 am -
2 stops9h 50m
Sat 12/128:15 am -
2 stops12h 30m
Deal found 10/20![Southwest logo]()
$252
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/241:20 pm -
1 stop5h 30m
Thu 12/317:55 am -
1 stop7h 55m
Deal found 10/19![Southwest logo]()
$254
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/151:20 pm -
1 stop5h 30m
Sat 12/193:10 pm -
2 stops9h 35m
Deal found 10/21![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:50 pm -
1 stop5h 55m
Mon 12/144:15 pm -
1 stop6h 10m
Deal found 10/21![Southwest logo]()
$266
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:00 am -
1 stop4h 20m
Sun 12/137:25 pm -
1 stop6h 20m
Deal found 10/20![Southwest logo]()
$274
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1112:45 pm -
2 stops6h 50m
Tue 12/157:05 am -
2 stops8h 00m
Deal found 10/20![Southwest logo]()
$277
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:50 pm -
1 stop6h 00m
Sun 12/137:25 pm -
1 stop6h 20m
Deal found 10/20![Southwest logo]()
$292
Best flights from Minneapolis to KnoxvilleDiscover carefully curated flight deals from Minneapolis to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
Discover carefully curated flight deals from Minneapolis to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:20 pm -
1 stop5h 30m
Sun 12/207:15 pm -
1 stop6h 45m
Deal found 10/21![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:05 am -
1 stop7h 08m
Sun 12/2012:11 pm -
1 stop6h 00m
Deal found 10/20![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:12 pm -
1 stop6h 42m
Fri 11/275:45 am -
1 stop5h 35m
Deal found 10/22![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop11h 45m
Tue 11/175:15 pm -
1 stop6h 45m
Deal found 10/20![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/124:25 pm -
1 stop6h 21m
Sun 2/147:55 am -
Nonstop2h 34m
Deal found 10/22![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:10 am -
1 stop4h 05m
Sun 1/244:40 pm -
1 stop7h 00m
Deal found 10/21![Southwest logo]()
$356
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:55 pm -
Nonstop2h 16m
Tue 11/176:30 pm -
Nonstop2h 35m
Deal found 10/18![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:55 pm -
2 stops7h 50m
Thu 12/32:40 pm -
2 stops8h 45m
Deal found 10/18![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:03 pm -
Nonstop2h 17m
Sun 11/298:04 am -
Nonstop2h 36m
Deal found 10/20![Delta logo]()
$429
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:00 am -
2 stops10h 50m
Mon 11/161:00 pm -
2 stops9h 55m
Deal found 10/22![Southwest logo]()
$414
Last-minute flights from Minneapolis to KnoxvilleDiscover last-minute flight deals from Minneapolis to Knoxville. Data last updated October 23, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to Knoxville. Data last updated October 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:19 pm -
1 stop4h 40m
Fri 10/305:26 pm -
1 stop6h 23m
Deal found 10/23![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:30 pm -
1 stop7h 17m
Mon 11/96:10 pm -
1 stop6h 17m
Deal found 10/23![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:32 pm -
1 stop21h 47m
Mon 11/162:21 pm -
2 stops24h 45m
Deal found 10/22![Multiple Airlines logo]()
$323
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop11h 45m
Tue 11/175:15 pm -
1 stop6h 45m
Deal found 10/20![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop11h 45m
Sun 11/157:25 pm -
1 stop6h 20m
Deal found 10/22![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:40 pm -
1 stop4h 05m
Wed 11/187:05 am -
1 stop4h 10m
Deal found 10/22![Southwest logo]()
$296
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/221:03 pm -
Nonstop2h 17m
Tue 12/17:59 am -
Nonstop2h 41m
Deal found 10/18![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:55 pm -
Nonstop2h 16m
Thu 12/36:17 pm -
1 stop7h 34m
Deal found 10/18![Delta logo]()
$349
One-way flights from Minneapolis to KnoxvilleSearch for one-way flight options from Minneapolis to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
Search for one-way flight options from Minneapolis to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/147:10 am -
1 stop4h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$118
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:35 am -
2 stops10h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:40 pm -
2 stops17h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$127
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:50 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$136
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:40 am -
1 stop8h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Southwest logo]()
$148
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:20 pm -
1 stop5h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$149
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:00 am -
2 stops10h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Southwest logo]()
$153
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/227:50 am -
2 stops9h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:32 pm -
1 stop21h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$156
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:00 am -
2 stops10h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$165
Find flight deals from Minneapolis to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $236 (Southwest) |
One-way from | $118 (Southwest) |
Popular in | October |
Cheapest in | August |
Average price | $552 |
Good round-trip deal | $458 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 23, 2026.
Use the filters below to find and compare flights from Minneapolis to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Thu 12/10
1:50 pm-8:50 pm
1 stop6h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$136
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Mon 11/16
1:50 pm-8:50 pm
1 stop6h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$148
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Sat 11/14
6:40 am-4:10 pm
1 stop8h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$148
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Fri 2/5
5:15 am-3:10 pm
1 stop8h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$149
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Fri 12/4
1:20 pm-7:50 pm
1 stop5h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$149
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Wed 11/11
2:32 pm-1:19 pm
1 stop21h 47m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$156
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Wed 11/11
9:00 am-8:50 pm
2 stops10h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$165
Quickest round-trip
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Fri 4/16
7:00 am-12:10 pm
1 stop4h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$210
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Wed 12/16
1:20 pm-7:50 pm
1 stop5h 30m
Knoxville McGhee Tyson
Sun 12/20
7:15 pm-1:00 am
1 stop6h 45m
$297
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Fri 11/13
6:00 am-6:45 pm
1 stop11h 45m
Knoxville McGhee Tyson
Tue 11/17
5:15 pm-11:00 pm
1 stop6h 45m
$310
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Minneapolis to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Minneapolis-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Minneapolis-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Minneapolis-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Minneapolis-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Minneapolis to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Minneapolis with our price prediction graph.
MSP-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to Knoxville
Prices
Airlines
More
How far ahead should I book a flight from Minneapolis to Knoxville?
The price you pay for your flight from Minneapolis to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 15 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Minneapolis to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Minneapolis to Knoxville (average of $359). Flying from Minneapolis to Knoxville in October is currently the most expensive (average of $552). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSP to TYS?
Find hourly flight availability from Minneapolis to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2026.
One of the essential ways to save on airfare from Minneapolis to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the morning could potentially save you up to 69% on airfare.
What’s the top layover airport for flights from Minneapolis to Knoxville?
Share of 1-stop round-trip flights from Minneapolis to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Denver (DEN) – chosen by Cheapflights users on 57% of 1-stop itineraries from Minneapolis to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Minneapolis to Knoxville?
Average round-trip fare for 1-stop flights from Minneapolis to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $252.
What’s the fastest layover option from Minneapolis to Knoxville?
Shortest average travel time for 1-stop one-way flights from Minneapolis to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Nashville (BNA) have the shortest average one-way travel time for 1-stop routes: 3h 48m.
Which airport typically offers the quickest layover for flights from Minneapolis to Knoxville?
Average layover duration for 1-stop one-way flights from Minneapolis to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Nashville (BNA) offer the fastest connection on this route, with an average layover time of 1h 19m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 23, 2026.
Read through reviews of airlines operating flights from Minneapolis to Knoxville, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.4
Food
7.0
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Food
7.0
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Food
7.0
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Food
7.0
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Food
7.0
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Newport
Bryson City
Murphy
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Top 4 airlines flying from Minneapolis to Knoxville
Discover the top 4 airlines that operate flights from Minneapolis to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$457 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$267 | Average$433 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$297 | Average$412 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$299 | Average$462 | FlexibilityNo cancel fee | On-timeN/A |