Knoxville

$68+ Cheap flights from Houston to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — TYS
May 1 — May 81
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Houston to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Houston to Knoxville McGhee Tyson are usually found in August or June, booked 87 days in advance, depart on a Tuesday or Monday and return on a Monday

Cheap flight deals from Houston to Knoxville

Cheapest flights from Houston to Knoxville
Explore the most affordable flight options available from Houston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:31 pm
HOU
-
TYS
Nonstop2h 09m
Allegiant Air
Mon 6/85:30 pm
TYS
-
HOU
Nonstop2h 11m
Allegiant Air
Deal found 3/30$100
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:39 pm
HOU
-
TYS
Nonstop2h 09m
Allegiant Air
Mon 7/135:32 pm
TYS
-
HOU
Nonstop2h 17m
Allegiant Air
Deal found 3/31$110
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:27 pm
HOU
-
TYS
Nonstop2h 07m
Allegiant Air
Fri 9/251:31 pm
TYS
-
HOU
Nonstop2h 20m
Allegiant Air
Deal found 3/31$112
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:27 pm
HOU
-
TYS
Nonstop2h 07m
Allegiant Air
Fri 10/212:57 pm
TYS
-
HOU
Nonstop2h 17m
Allegiant Air
Deal found 3/31$117
This Booking.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:39 pm
HOU
-
TYS
Nonstop2h 03m
Allegiant Air
Mon 5/255:30 pm
TYS
-
HOU
Nonstop2h 19m
Allegiant Air
Deal found 3/27$123
This Cheapflightsfares deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:39 pm
HOU
-
TYS
Nonstop2h 09m
Allegiant Air
Mon 7/65:32 pm
TYS
-
HOU
Nonstop2h 17m
Allegiant Air
Deal found 3/29$127
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:45 am
IAH
-
TYS
1 stop7h 48m
Frontier
Thu 4/304:28 pm
TYS
-
IAH
1 stop9h 20m
Frontier
Deal found 3/31$140
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:32 pm
HOU
-
TYS
Nonstop2h 07m
Allegiant Air
Mon 9/71:22 pm
TYS
-
HOU
Nonstop2h 20m
Allegiant Air
Deal found 3/31$148
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:41 pm
HOU
-
TYS
Nonstop2h 07m
Allegiant Air
Mon 9/282:17 pm
TYS
-
HOU
Nonstop2h 20m
Allegiant Air
Deal found 3/31$156
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:16 pm
IAH
-
TYS
1 stop21h 20m
Multiple Airlines
Thu 5/79:40 pm
TYS
-
IAH
1 stop18h 23m
Multiple Airlines
Deal found 3/31$180
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:46 am
IAH
-
TYS
1 stop9h 56m
Multiple Airlines
Mon 4/271:15 pm
TYS
-
IAH
1 stop20h 23m
Multiple Airlines
Deal found 3/27$184
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:16 pm
IAH
-
TYS
1 stop21h 20m
Multiple Airlines
Thu 4/309:25 pm
TYS
-
IAH
1 stop15h 02m
Multiple Airlines
Deal found 3/31$191

Find flight deals from Houston to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 1, 2026.

Round-trip from

$100
(Cheapflightsfares)

One-way from

$68
(Cheapflightsfares)

Popular in

September

Cheapest in

August

Average price

$325
From Houston to Knoxville McGhee Tyson
One-way flight from Houston to Knoxville McGhee Tyson
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Houston to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Tue 5/5

6:00 am-11:17 am

1 stop4h 17m

Knoxville McGhee Tyson

Tue 5/12

7:27 am-12:11 pm

1 stop5h 44m

$289

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Mon 4/20

7:00 am-2:10 pm

1 stop6h 10m

Knoxville McGhee Tyson

Tue 4/21

8:15 am-3:00 pm

1 stop7h 45m

$289

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Mon 5/4

10:53 am-3:52 pm

1 stop3h 59m

Knoxville McGhee Tyson

Tue 5/12

7:27 am-12:11 pm

1 stop5h 44m

$289

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Wed 5/13

6:00 am-11:09 am

1 stop4h 09m

Knoxville McGhee Tyson

Tue 5/19

8:35 am-12:11 pm

1 stop4h 36m

$289

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Fri 4/17

8:21 pm-11:41 pm

Nonstop2h 20m

Knoxville McGhee Tyson

Mon 4/27

7:05 am-8:46 am

Nonstop2h 41m

$291

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Wed 5/27

2:45 pm-6:07 pm

Nonstop2h 22m

Knoxville McGhee Tyson

Sat 5/30

7:15 am-8:40 am

Nonstop2h 25m

$293

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Sun 4/26

6:10 am-3:15 pm

1 stop8h 05m

Knoxville McGhee Tyson

Fri 5/8

6:35 am-11:45 am

2 stops6h 10m

$294

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Mon 5/4

10:20 am-9:15 pm

2 stops9h 55m

Knoxville McGhee Tyson

Wed 5/6

5:50 pm-10:50 pm

1 stop6h 00m

$294

HoustonKnoxville

HOU - TYS

HOUTYS

Houston Hobby

Wed 4/15

1:00 pm-7:40 pm

1 stop5h 40m

Knoxville McGhee Tyson

Tue 4/21

7:05 am-1:45 pm

2 stops7h 40m

$314

HoustonKnoxville

IAH - TYS

IAHTYS

Houston George Bush Intcntl

Fri 6/19

2:43 pm-7:55 pm

1 stop4h 12m

Knoxville McGhee Tyson

Tue 6/23

6:05 pm-9:23 pm

1 stop4h 18m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 39 resultsSorted by cheapest first
1
2
3
4

Best time to book a flight from Houston to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Knoxville

How far ahead should I book a flight from Houston to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Houston to Knoxville. Price data was last updated on March 13, 2026.

Booking 87 days in advance of your planned departure date is, on average, the best time to get cheap flights from Houston to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Houston to Knoxville?

Currently, December is the cheapest month in which you can book a flight from Houston to Knoxville (average of $52). Flying from Houston to Knoxville in January is currently the most expensive (average of $209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to TYS?

Find hourly flight availability from Houston to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2026.

When flying from Houston to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 41% versus a flight in the afternoon.

What is the cheapest day to fly from Houston to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Houston to Knoxville. Price data was last updated on March 28, 2026.

Travelers seeking maximum savings on their Houston to Knoxville flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Houston to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 1, 2026.
See what other customers who have flown with Delta,United Airlines, andAllegiant Air from Houston to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Houston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Knoxville from Houston?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Houston. On average, McGhee Tyson has 0 inbound flights from Houston per day from 4 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Houston to Knoxville?

    For as low as $291, Delta can have you in Knoxville from Houston in 2h 20m. Airlines will cover a distance of 770 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Houston to Knoxville round-trip?

    According to our current data, Allegiant Air ($52), Delta ($104), and United Airlines ($209) offers the cheapest pricing from Houston to Knoxville. Allegiant Air is currently priced 82% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Houston to Knoxville one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $51. Users have also found prices from $107 and $133 on American Airlines and United Airlines, respectively.

  • What are the cheapest flights from Houston to Knoxville?

    Looking for the cheapest flight from Houston to Knoxville? While on average our users pay $125, our data indicates the cheapest price to be $73. The most popular route (Houston George Bush Intcntl - Knoxville McGhee Tyson), is priced around $195.

  • Can I find deals for flights from Houston to Knoxville that include hotel bookings?

    Yes. In addition to deals on Houston to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Knoxville.

  • Can I find deals for business class flights from Houston to Knoxville?

    Yes. Cheapflights offers flight deals from Houston to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Knoxville?

    Currently, December is the cheapest month in which you can book a flight from Houston to Knoxville (average of $52). Flying from Houston to Knoxville in January is currently the most expensive (average of $209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Houston to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Houston to Knoxville

Discover the top 4 airlines that operate flights from Houston to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$52Average$108FlexibilityNo cancel feeOn-time88%
DeltaCheapest$104Average$306FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$209Average$393FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$391FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.