$148+ Cheap flights from San Antonio to Knoxville (SAT - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Jul 25 — Aug 11
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Knoxville
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Best
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Cheapest flights from San Antonio to KnoxvilleExplore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
This CheapOair deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:49 pm
SAT
- TYS
1 stop22h 35m
Frontier
Mon 8/178:19 pm
TYS
- SAT
1 stop23h 35m
Frontier
Deal found 6/22![Frontier logo]()
$264
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:45 pm
SAT
- TYS
1 stop5h 09m
Delta
Tue 8/116:12 pm
TYS
- SAT
1 stop7h 16m
Delta
Deal found 6/24![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:50 am
SAT
- TYS
1 stop7h 05m
Southwest
Tue 8/1112:45 pm
TYS
- SAT
2 stops8h 45m
Southwest
Deal found 6/22![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:05 pm
SAT
- TYS
1 stop7h 05m
Delta
Mon 8/106:12 pm
TYS
- SAT
1 stop7h 16m
Delta
Deal found 6/21![Delta logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:39 pm
SAT
- TYS
1 stop22h 45m
Multiple Airlines
Mon 8/106:29 pm
TYS
- SAT
2 stops27h 08m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/711:30 am
SAT
- TYS
2 stops21h 56m
Multiple Airlines
Sun 8/97:00 am
TYS
- SAT
1 stop12h 54m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:39 pm
SAT
- TYS
1 stop22h 45m
Multiple Airlines
Sun 8/97:00 am
TYS
- SAT
1 stop12h 54m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am
SAT
- TYS
1 stop6h 05m
Delta
Sat 10/318:47 am
TYS
- SAT
1 stop7h 41m
Delta
Deal found 6/23![Delta logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:49 pm
SAT
- TYS
2 stops25h 55m
Multiple Airlines
Sun 8/167:00 am
TYS
- SAT
1 stop12h 54m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/711:30 am
SAT
- TYS
2 stops21h 56m
Multiple Airlines
Mon 8/108:19 pm
TYS
- SAT
1 stop23h 35m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:35 am
SAT
- TYS
2 stops5h 45m
Southwest
Sat 8/86:50 am
TYS
- SAT
2 stops5h 55m
Southwest
Deal found 6/21![Southwest logo]()
$345
Best flights from San Antonio to KnoxvilleDiscover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
Discover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:50 am
SAT
- TYS
1 stop7h 05m
Southwest
Tue 8/1112:45 pm
TYS
- SAT
2 stops8h 45m
Southwest
Deal found 6/22![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:16 pm
SAT
- TYS
1 stop4h 36m
Delta
Wed 7/156:05 pm
TYS
- SAT
1 stop7h 15m
Delta
Deal found 6/20![Delta logo]()
$356
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:15 pm
SAT
- TYS
1 stop6h 30m
United Airlines
Wed 8/122:21 pm
TYS
- SAT
1 stop6h 37m
United Airlines
Deal found 6/21![United Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:20 am
SAT
- TYS
1 stop4h 50m
Delta
Tue 7/216:05 pm
TYS
- SAT
1 stop7h 15m
Delta
Deal found 6/24![Delta logo]()
$356
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:30 am
SAT
- TYS
1 stop4h 49m
United Airlines
Sat 8/86:00 am
TYS
- SAT
2 stops10h 39m
United Airlines
Deal found 6/24![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 am
SAT
- TYS
1 stop6h 30m
Southwest
Fri 8/287:10 am
TYS
- SAT
2 stops6h 40m
Southwest
Deal found 6/24![Southwest logo]()
$382
Last-minute flights from San Antonio to KnoxvilleDiscover last-minute flight deals from San Antonio to Knoxville. Data last updated June 25, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Knoxville. Data last updated June 25, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:51 pm
SAT
- TYS
1 stop22h 46m
Frontier
Wed 7/18:32 pm
TYS
- SAT
1 stop23h 24m
Frontier
Deal found 6/24![Frontier logo]()
$385
This CheapOair deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:51 pm
SAT
- TYS
1 stop22h 46m
Frontier
Mon 6/298:32 pm
TYS
- SAT
1 stop23h 24m
Frontier
Deal found 6/22![Frontier logo]()
$390
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:12 pm
SAT
- TYS
1 stop5h 50m
Delta
Tue 7/147:43 pm
TYS
- SAT
1 stop5h 37m
Delta
Deal found 6/23![Delta logo]()
$378
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:20 am
SAT
- TYS
1 stop4h 50m
Delta
Wed 7/155:40 am
TYS
- SAT
1 stop5h 03m
Delta
Deal found 6/23![Delta logo]()
$386
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:45 am
SAT
- TYS
2 stops8h 30m
Southwest
Tue 7/146:55 pm
TYS
- SAT
1 stop6h 00m
Southwest
Deal found 6/21![Southwest logo]()
$391
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:40 am
SAT
- TYS
1 stop7h 08m
Delta
Wed 7/1511:57 am
TYS
- SAT
1 stop6h 32m
Delta
Deal found 6/23![Delta logo]()
$295
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:20 am
SAT
- TYS
1 stop4h 50m
Delta
Fri 7/177:49 pm
TYS
- SAT
1 stop5h 31m
Delta
Deal found 6/23![Delta logo]()
$356
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:10 am
SAT
- TYS
2 stops6h 55m
Southwest
Mon 7/206:40 am
TYS
- SAT
1 stop11h 05m
Southwest
Deal found 6/24![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:30 am
SAT
- TYS
2 stops10h 30m
Southwest
Sun 7/197:00 pm
TYS
- SAT
1 stop7h 10m
Southwest
Deal found 6/21![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:00 pm
SAT
- TYS
2 stops8h 20m
Southwest
Wed 7/296:55 pm
TYS
- SAT
1 stop6h 00m
Southwest
Deal found 6/22![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:35 pm
SAT
- TYS
1 stop5h 16m
American Airlines
Mon 8/38:11 pm
TYS
- SAT
1 stop4h 47m
American Airlines
Deal found 6/22![American Airlines logo]()
$377
One-way flights from San Antonio to KnoxvilleSearch for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
Search for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:40 am
SAT
- TYS
1 stop6h 35m
Southwest
Deal found 6/24![Southwest logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:38 pm
SAT
- TYS
2 stops28h 27m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$173
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:10 am
SAT
- TYS
1 stop5h 15m
Southwest
Deal found 6/24![Southwest logo]()
$189
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:51 pm
SAT
- TYS
1 stop22h 46m
Frontier
Deal found 6/24![Frontier logo]()
$191
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:16 pm
SAT
- TYS
1 stop4h 36m
Delta
Deal found 6/23![Delta logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:37 pm
SAT
- TYS
3 stops24h 19m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$288
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:20 am
SAT
- TYS
2 stops7h 40m
Southwest
Deal found 6/24![Southwest logo]()
$295
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:30 am
SAT
- TYS
2 stops10h 30m
United Airlines
Deal found 6/23![United Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:56 pm
SAT
- TYS
3 stops20h 03m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$563
Find flight deals from San Antonio to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $264 (CheapOair) |
One-way from | $148 (Southwest) |
Popular in | March |
Cheapest in | January |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Wed 8/5
10:50 am-6:55 pm
1 stop7h 05m
Knoxville McGhee Tyson
Tue 8/11
12:45 pm-8:30 pm
2 stops8h 45m
$300
Quickest round-trip
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Sun 7/12
6:16 pm-11:52 pm
1 stop4h 36m
Knoxville McGhee Tyson
Wed 7/15
6:05 pm-12:20 am
1 stop7h 15m
$356
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Thu 7/16
5:20 am-11:10 am
1 stop4h 50m
Knoxville McGhee Tyson
Tue 7/21
6:05 pm-12:20 am
1 stop7h 15m
$356
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Tue 8/11
2:15 pm-9:45 pm
1 stop6h 30m
Knoxville McGhee Tyson
Wed 8/12
2:21 pm-7:58 pm
1 stop6h 37m
$375
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Tue 8/4
5:30 am-11:19 am
1 stop4h 49m
Knoxville McGhee Tyson
Sat 8/8
6:00 am-3:39 pm
2 stops10h 39m
$380
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Fri 8/21
11:05 am-6:35 pm
1 stop6h 30m
Knoxville McGhee Tyson
Fri 8/28
7:10 am-12:50 pm
2 stops6h 40m
$382
Cheapest one-way
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Sat 9/12
6:10 am-1:15 pm
2 stops6h 05m
$175
Quickest one-way
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Fri 7/10
6:16 pm-11:52 pm
1 stop4h 36m
$239
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Sat 9/12
8:37 pm-9:56 pm
3 stops24h 19m
$288
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Fri 7/10
5:30 am-5:00 pm
2 stops10h 30m
$363
Sorted by cheapest first
Compare providers for flights from San Antonio to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Knoxville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
SAT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Knoxville
How far ahead should I book a flight from San Antonio to Knoxville?
Booking 42 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Antonio to Knoxville?
Currently, January is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $283). Flying from San Antonio to Knoxville in March is currently the most expensive (average of $518). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 25, 2026.
Read through reviews of airlines operating flights from San Antonio to Knoxville, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Overall
7.9
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
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Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Crossville
Morristown
Bryson City
Murphy
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Top 4 airlines flying from San Antonio to Knoxville
Discover the top 4 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$341 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$168 | Average$336 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$216 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$242 | Average$355 | FlexibilityNo cancel fee | On-time63% |