$159+ Cheap flights from San Antonio to Knoxville (SAT - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Knoxville
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Cheapest flights from San Antonio to KnoxvilleExplore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:45 pm -
1 stop4h 55m
Sat 12/125:17 pm -
1 stop5h 43m
Deal found 11/7![American Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:16 am -
1 stop4h 46m
Wed 12/912:32 pm -
1 stop5h 59m
Deal found 11/6![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:47 am -
2 stops8h 00m
Sat 12/55:00 pm -
1 stop5h 26m
Deal found 11/9![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:37 pm -
1 stop4h 20m
Sun 12/65:40 am -
1 stop5h 08m
Deal found 11/5![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:38 am -
1 stop5h 13m
Sat 12/56:17 pm -
1 stop6h 18m
Deal found 11/6![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
2 stops9h 40m
Tue 12/84:15 pm -
1 stop6h 30m
Deal found 11/6![Southwest logo]()
$359
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:37 pm -
1 stop4h 20m
Tue 12/86:17 pm -
1 stop7h 18m
Deal found 11/6![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:38 am -
1 stop5h 13m
Thu 12/105:40 am -
1 stop5h 08m
Deal found 11/6![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:00 pm -
2 stops7h 50m
Thu 12/177:25 pm -
1 stop6h 35m
Deal found 11/9![Southwest logo]()
$374
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:37 pm -
1 stop4h 20m
Thu 12/105:40 am -
1 stop5h 08m
Deal found 11/6![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:37 pm -
1 stop4h 55m
Fri 12/41:38 pm -
1 stop7h 14m
Deal found 11/10![American Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:16 am -
1 stop5h 11m
Tue 12/85:40 am -
1 stop5h 08m
Deal found 11/6![Delta logo]()
$388
Best flights from San Antonio to KnoxvilleDiscover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/94:56 pm -
1 stop4h 27m
Wed 1/132:35 pm -
1 stop6h 46m
Deal found 11/7![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:10 am -
1 stop4h 10m
Thu 12/1712:50 pm -
1 stop7h 20m
Deal found 11/9![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/82:10 pm -
1 stop6h 49m
Wed 1/1311:53 am -
1 stop4h 37m
Deal found 11/7![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:25 am -
2 stops10h 15m
Sat 12/122:50 pm -
2 stops7h 20m
Deal found 11/7![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:15 am -
1 stop4h 57m
Mon 1/115:55 pm -
1 stop6h 18m
Deal found 11/5![United Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/76:45 am -
1 stop5h 43m
Thu 3/115:05 pm -
1 stop6h 22m
Deal found 11/5![Delta logo]()
$437
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/302:50 pm -
2 stops6h 50m
Mon 12/75:15 pm -
1 stop6h 55m
Deal found 11/5![Southwest logo]()
$432
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:15 am -
2 stops10h 39m
Sun 1/1711:53 am -
1 stop4h 37m
Deal found 11/5![United Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:10 am -
1 stop7h 55m
Thu 12/32:40 pm -
1 stop7h 00m
Deal found 11/7![Southwest logo]()
$453
Last-minute flights from San Antonio to KnoxvilleDiscover last-minute flight deals from San Antonio to Knoxville. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Knoxville. Data last updated November 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:47 am -
2 stops8h 00m
Sat 12/55:00 pm -
1 stop5h 26m
Deal found 11/9![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:37 pm -
1 stop4h 55m
Fri 12/41:38 pm -
1 stop7h 14m
Deal found 11/10![American Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:38 am -
1 stop5h 13m
Sat 12/56:17 pm -
1 stop6h 18m
Deal found 11/6![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:38 am -
1 stop5h 13m
Thu 12/36:17 pm -
1 stop7h 18m
Deal found 11/6![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:37 pm -
1 stop4h 20m
Sun 12/65:40 am -
1 stop5h 08m
Deal found 11/5![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:37 pm -
1 stop4h 20m
Tue 12/86:17 pm -
1 stop7h 18m
Deal found 11/6![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:37 pm -
1 stop4h 20m
Thu 12/105:40 am -
1 stop5h 08m
Deal found 11/6![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:45 pm -
1 stop4h 55m
Sat 12/125:17 pm -
1 stop5h 43m
Deal found 11/7![American Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:16 am -
1 stop4h 46m
Tue 12/86:17 pm -
1 stop5h 02m
Deal found 11/6![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
2 stops9h 40m
Tue 12/84:15 pm -
1 stop6h 30m
Deal found 11/6![Southwest logo]()
$359
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:37 pm -
1 stop4h 20m
Wed 12/94:01 pm -
1 stop7h 18m
Deal found 11/6![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:00 pm -
2 stops7h 50m
Thu 12/177:25 pm -
1 stop6h 35m
Deal found 11/9![Southwest logo]()
$374
One-way flights from San Antonio to KnoxvilleSearch for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:05 pm -
1 stop4h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Delta logo]()
$159
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1211:47 am -
2 stops8h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![United Airlines logo]()
$175
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/18:20 am -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Southwest logo]()
$195
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:40 pm -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Southwest logo]()
$210
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:40 pm -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Southwest logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:30 pm -
2 stops48h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$220
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:55 am -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Southwest logo]()
$225
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:50 pm -
2 stops6h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Southwest logo]()
$230
Find flight deals from San Antonio to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $338 (American Airlines) |
One-way from | $159 (Delta) |
Popular in | April |
Cheapest in | May |
Average price | $389 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Sat 12/12
5:05 pm-10:17 pm
1 stop4h 12m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$159
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Sat 12/12
11:47 am-8:47 pm
2 stops8h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Fri 1/1
8:20 am-2:05 pm
1 stop4h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Tue 12/22
8:30 pm-10:14 pm
2 stops48h 44m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$220
Quickest round-trip
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Tue 12/22
5:40 pm-10:40 pm
1 stop4h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$225
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Sat 12/19
2:35 pm-10:45 pm
2 stops7h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$243
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Mon 12/21
2:50 pm-10:40 pm
2 stops6h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$260
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Sat 12/12
6:47 pm-6:42 pm
3 stops46h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$261
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Sat 1/9
4:56 pm-10:23 pm
1 stop4h 27m
Knoxville McGhee Tyson
Wed 1/13
2:35 pm-8:21 pm
1 stop6h 46m
$339
San AntonioKnoxville
SAT San Antonio - TYS Knoxville McGhee Tyson
SATTYS
San Antonio
Tue 12/15
7:10 am-12:20 pm
1 stop4h 10m
Knoxville McGhee Tyson
Thu 12/17
12:50 pm-7:10 pm
1 stop7h 20m
$354
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Knoxville in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
SAT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Knoxville
How far ahead should I book a flight from San Antonio to Knoxville?
Booking 12 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Antonio to Knoxville?
Currently, May is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $287). Flying from San Antonio to Knoxville in April is currently the most expensive (average of $488). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Knoxville?
Airfare is below average for this route at the moment.
San Antonio to Knoxville flights typically cost between $340 and $516 in December.The cheapest round-trip price found within the last 5 days was $338 on American Airlines (Dec 5-Dec 12).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 10, 2026.
Read through reviews of airlines operating flights from San Antonio to Knoxville, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.4
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.4
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.4
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.4
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.4
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 4 airlines flying from San Antonio to Knoxville
Discover the top 4 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$168 | Average$369 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$243 | Average$388 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$384 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$268 | Average$423 | FlexibilityNo cancel fee | On-time71% |