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$244+ Cheap flights from Amarillo to Knoxville (AMA - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — TYS
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Amarillo to Knoxville

Cheapest flights from Amarillo to Knoxville
Explore the most affordable flight options available from Amarillo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:00 pm
AMA
-
TYS
1 stop5h 30m
United Airlines
Sat 9/127:15 am
TYS
-
AMA
1 stop5h 05m
United Airlines
Deal found 4/23$297
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am
AMA
-
TYS
1 stop6h 20m
Southwest
Sat 9/123:35 pm
TYS
-
AMA
1 stop5h 30m
Southwest
Deal found 4/23$338
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:00 am
AMA
-
TYS
1 stop8h 05m
United Airlines
Wed 8/127:15 am
TYS
-
AMA
1 stop5h 05m
United Airlines
Deal found 4/23$349
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
AMA
-
TYS
1 stop6h 03m
American Airlines
Mon 7/68:11 pm
TYS
-
AMA
1 stop4h 48m
American Airlines
Deal found 4/24$408
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 am
AMA
-
TYS
1 stop4h 22m
American Airlines
Tue 5/124:09 pm
TYS
-
AMA
1 stop4h 48m
American Airlines
Deal found 4/23$420

Find flight deals from Amarillo to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Amarillo (AMA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$297
(United Airlines)

One-way from

$244
(American Airlines)

Popular in

March

Cheapest in

February

Average price

$388
Provider with most accurate pricing for Amarillo-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Amarillo-Knoxville McGhee Tyson flights.
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From Amarillo to Knoxville McGhee Tyson
Search Deals
One-way flight from Amarillo to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Amarillo to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Tue 9/8

3:00 pm-9:30 pm

1 stop5h 30m

Knoxville McGhee Tyson

Sat 9/12

7:15 am-11:20 am

1 stop5h 05m

$297

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Tue 9/8

7:00 am-2:20 pm

1 stop6h 20m

Knoxville McGhee Tyson

Sat 9/12

3:35 pm-8:05 pm

1 stop5h 30m

$338

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Tue 8/11

9:00 am-6:05 pm

1 stop8h 05m

Knoxville McGhee Tyson

Wed 8/12

7:15 am-11:20 am

1 stop5h 05m

$349
Cheapest one-way
Quickest one-way

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Sat 5/9

6:00 am-12:30 pm

1 stop5h 30m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Sorted by cheapest first

Compare providers for flights from Amarillo to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Amarillo to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Amarillo-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Amarillo-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Amarillo-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Amarillo-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Amarillo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Amarillo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to Knoxville

How much does it cost to fly round-trip from Amarillo to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown American Airlines from Amarillo to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,667 reviews

Boarding

7.5

Comfort

7.2

Crew

7.9

Overall

7.1

Food

6.4

Entertainment

6.9

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.1
Good
11,667 reviews
American Airlines
7.1
Good
11,667 reviews

Boarding

7.5

Comfort

7.2

Crew

7.9

Overall

7.1

Food

6.4

Entertainment

6.9

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Amarillo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Amarillo to Knoxville?

    For as low as $297, United Airlines can have you in Knoxville from Amarillo in 5h 30m. Airlines will cover a distance of 995 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Amarillo to Knoxville round-trip?

    American Airlines, at $305, was found to be the cheapest airline from Amarillo to Knoxville.. This flight start at 26% lower than the current average price 3 months from now.

  • Can I find deals for flights from Amarillo to Knoxville that include hotel bookings?

    Yes. In addition to deals on Amarillo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to Knoxville.

  • Can I find deals for business class flights from Amarillo to Knoxville?

    Yes. Cheapflights offers flight deals from Amarillo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top airline flying from Amarillo to Knoxville

Discover the top airline that operate flights from Amarillo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$305Average$330FlexibilityNo cancel feeOn-time71%

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