$393+ Cheap flights from Amarillo to Knoxville (AMA - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — TYS
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Amarillo to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Amarillo to Knoxville
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Best
Last-minute
Cheapest flights from Amarillo to KnoxvilleExplore the most affordable flight options available from Amarillo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Amarillo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:14 pm -
1 stop5h 18m
Wed 11/185:32 pm -
1 stop4h 57m
Deal found 9/5![American Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:14 pm -
1 stop5h 18m
Mon 11/235:30 am -
1 stop7h 54m
Deal found 9/5![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
2 stops9h 40m
Wed 11/187:05 am -
2 stops7h 10m
Deal found 9/5![Southwest logo]()
$403
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
1 stop7h 05m
Mon 11/237:05 am -
2 stops7h 00m
Deal found 9/5![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am -
2 stops13h 25m
Sun 10/114:15 pm -
2 stops8h 40m
Deal found 9/8![Southwest logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:57 pm -
1 stop4h 55m
Mon 9/142:43 pm -
1 stop7h 35m
Deal found 9/8![American Airlines logo]()
$593
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:10 am -
2 stops10h 35m
Mon 9/141:00 pm -
2 stops10h 10m
Deal found 9/8![Southwest logo]()
$603
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:20 pm -
1 stop5h 58m
Mon 10/195:26 pm -
1 stop6h 18m
Deal found 9/9![American Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:20 pm -
1 stop5h 58m
Sun 10/116:00 am -
1 stop4h 52m
Deal found 9/8![American Airlines logo]()
$677
Best flights from Amarillo to KnoxvilleDiscover carefully curated flight deals from Amarillo to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Amarillo to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
2 stops9h 40m
Wed 11/187:05 am -
2 stops7h 10m
Deal found 9/5![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:19 pm -
1 stop5h 55m
Thu 1/74:25 pm -
1 stop6h 11m
Deal found 9/9![United Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:20 pm -
1 stop5h 58m
Mon 10/195:26 pm -
1 stop6h 18m
Deal found 9/9![American Airlines logo]()
$629
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
1 stop7h 05m
Mon 11/237:05 am -
2 stops7h 00m
Deal found 9/5![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am -
2 stops13h 25m
Sun 10/114:15 pm -
2 stops8h 40m
Deal found 9/8![Southwest logo]()
$575
Last-minute flights from Amarillo to KnoxvilleDiscover last-minute flight deals from Amarillo to Knoxville. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Amarillo to Knoxville. Data last updated September 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:57 pm -
1 stop4h 55m
Mon 9/142:43 pm -
1 stop7h 35m
Deal found 9/8![American Airlines logo]()
$593
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:10 am -
2 stops10h 35m
Mon 9/141:00 pm -
2 stops10h 10m
Deal found 9/8![Southwest logo]()
$603
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am -
2 stops13h 25m
Sun 10/114:15 pm -
2 stops8h 40m
Deal found 9/8![Southwest logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:20 pm -
1 stop5h 58m
Sun 10/116:00 am -
1 stop4h 52m
Deal found 9/8![American Airlines logo]()
$677
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:45 pm -
2 stops9h 14m
Sun 10/116:00 am -
1 stop4h 52m
Deal found 9/8![American Airlines logo]()
$707
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:20 pm -
1 stop5h 58m
Fri 10/165:26 pm -
1 stop5h 08m
Deal found 9/7![American Airlines logo]()
$733
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:20 pm -
2 stops6h 25m
Fri 10/161:50 pm -
1 stop4h 25m
Deal found 9/7![Southwest logo]()
$748
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:20 pm -
1 stop5h 58m
Mon 10/195:26 pm -
1 stop6h 18m
Deal found 9/9![American Airlines logo]()
$629
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:30 pm -
2 stops7h 15m
Mon 10/191:50 pm -
1 stop10h 50m
Deal found 9/9![Southwest logo]()
$764
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:30 pm -
2 stops7h 15m
Sun 10/185:55 pm -
1 stop7h 00m
Deal found 9/9![Southwest logo]()
$818
Find flight deals from Amarillo to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Amarillo (AMA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $393 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Amarillo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Amarillo to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
AmarilloKnoxville
AMA Amarillo - TYS Knoxville McGhee Tyson
AMATYS
Amarillo
Tue 11/17
6:00 am-4:40 pm
2 stops9h 40m
Knoxville McGhee Tyson
Wed 11/18
7:05 am-1:15 pm
2 stops7h 10m
$403
AmarilloKnoxville
AMA Amarillo - TYS Knoxville McGhee Tyson
AMATYS
Amarillo
Mon 11/16
6:00 am-2:05 pm
1 stop7h 05m
Knoxville McGhee Tyson
Mon 11/23
7:05 am-1:05 pm
2 stops7h 00m
$404
Quickest round-trip
AmarilloKnoxville
AMA Amarillo - TYS Knoxville McGhee Tyson
AMATYS
Amarillo
Wed 1/6
3:19 pm-10:14 pm
1 stop5h 55m
Knoxville McGhee Tyson
Thu 1/7
4:25 pm-9:36 pm
1 stop6h 11m
$413
AmarilloKnoxville
AMA Amarillo - TYS Knoxville McGhee Tyson
AMATYS
Amarillo
Wed 10/7
5:45 am-8:10 pm
2 stops13h 25m
Knoxville McGhee Tyson
Sun 10/11
4:15 pm-11:55 pm
2 stops8h 40m
$575
AmarilloKnoxville
AMA Amarillo - TYS Knoxville McGhee Tyson
AMATYS
Amarillo
Fri 10/16
4:20 pm-11:18 pm
1 stop5h 58m
Knoxville McGhee Tyson
Mon 10/19
5:26 pm-10:44 pm
1 stop6h 18m
$629
Sorted by cheapest first
Compare providers for flights from Amarillo to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Amarillo to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Amarillo-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Amarillo-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Amarillo-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Amarillo-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Amarillo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Amarillo to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Amarillo with our price prediction graph.
AMA-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 10, 2026.
Read reviews from past customers who have flown American Airlines from Amarillo to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Entertainment
6.8
Comfort
7.2
Boarding
7.5
Overall
7.1
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Crew
7.9
Entertainment
6.8
Comfort
7.2
Boarding
7.5
Overall
7.1
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Amarillo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
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Top airline flying from Amarillo to Knoxville
Discover the top airline that operate flights from Amarillo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$336 | Average$514 | FlexibilityNo cancel fee | On-time71% |