$528+ Cheap flights from Tyler to Knoxville (TYR - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYR — TYS
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Find cheap flights from Tyler to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tyler to Knoxville
Cheapest
Best
Last-minute
Cheapest flights from Tyler to KnoxvilleExplore the most affordable flight options available from Tyler to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Tyler to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:35 pm -
1 stop4h 43m
Sat 9/126:00 am -
1 stop4h 52m
Deal found 8/23![American Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:32 pm -
1 stop4h 50m
Sun 9/135:35 pm -
1 stop7h 02m
Deal found 8/25![American Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:59 am -
1 stop4h 44m
Sun 9/68:05 pm -
1 stop4h 23m
Deal found 8/22![American Airlines logo]()
$622
Best flights from Tyler to KnoxvilleDiscover carefully curated flight deals from Tyler to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Tyler to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:35 pm -
1 stop4h 43m
Sat 9/126:00 am -
1 stop4h 52m
Deal found 8/23![American Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:10 am -
2 stops7h 23m
Sun 9/136:00 am -
1 stop4h 52m
Deal found 8/25![American Airlines logo]()
$586
Last-minute flights from Tyler to KnoxvilleDiscover last-minute flight deals from Tyler to Knoxville. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Tyler to Knoxville. Data last updated August 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:59 am -
1 stop4h 44m
Sun 9/68:05 pm -
1 stop4h 23m
Deal found 8/22![American Airlines logo]()
$622
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:35 pm -
1 stop4h 43m
Sat 9/126:00 am -
1 stop4h 52m
Deal found 8/23![American Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:32 pm -
1 stop4h 50m
Sun 9/135:35 pm -
1 stop7h 02m
Deal found 8/25![American Airlines logo]()
$580
Find flight deals from Tyler to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Tyler (TYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $528 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Tyler to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Tyler to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
TylerKnoxville
TYR Tyler Pounds Field - TYS Knoxville McGhee Tyson
TYRTYS
Tyler Pounds Field
Tue 9/8
5:35 pm-11:18 pm
1 stop4h 43m
Knoxville McGhee Tyson
Sat 9/12
6:00 am-9:52 am
1 stop4h 52m
$528
TylerKnoxville
TYR Tyler Pounds Field - TYS Knoxville McGhee Tyson
TYRTYS
Tyler Pounds Field
Wed 9/9
5:10 am-1:33 pm
2 stops7h 23m
Knoxville McGhee Tyson
Sun 9/13
6:00 am-9:52 am
1 stop4h 52m
$586
Sorted by cheapest first
Compare providers for flights from Tyler to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tyler to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Tyler-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tyler-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tyler-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tyler-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tyler-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tyler to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Tyler with our price prediction graph.
TYR-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Tyler to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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