$140+ Cheap flights from McAllen to Knoxville (MFE - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — TYS
Jul 11 — Jul 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from McAllen to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from McAllen to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from McAllen to KnoxvilleExplore the most affordable flight options available from McAllen to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
Explore the most affordable flight options available from McAllen to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:43 am
MFE
- TYS
1 stop10h 18m
Allegiant Air
Mon 8/32:47 pm
TYS
- MFE
1 stop26h 17m
Allegiant Air
Deal found 6/8![Allegiant Air logo]()
$439
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2512:35 pm
MFE
- TYS
2 stops10h 09m
Delta
Mon 8/35:40 am
TYS
- MFE
2 stops7h 17m
Delta
Deal found 6/8![Delta logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:43 am
MFE
- TYS
1 stop10h 18m
Multiple Airlines
Mon 8/37:20 pm
TYS
- MFE
2 stops45h 44m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:20 am
MFE
- TYS
2 stops8h 28m
Delta
Mon 8/35:40 am
TYS
- MFE
2 stops7h 17m
Delta
Deal found 6/7![Delta logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:18 pm
MFE
- TYS
1 stop27h 11m
Allegiant Air
Sun 6/287:01 pm
TYS
- MFE
1 stop13h 53m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$505
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:39 am
MFE
- TYS
1 stop7h 52m
American Airlines
Tue 6/165:37 am
TYS
- MFE
1 stop5h 22m
American Airlines
Deal found 6/7![American Airlines logo]()
$509
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/269:59 pm
MFE
- TYS
1 stop14h 58m
Allegiant Air
Mon 8/32:47 pm
TYS
- MFE
1 stop26h 17m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$523
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:37 am
MFE
- TYS
1 stop7h 53m
American Airlines
Mon 8/38:11 pm
TYS
- MFE
1 stop5h 04m
American Airlines
Deal found 6/8![American Airlines logo]()
$540
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/269:59 pm
MFE
- TYS
1 stop14h 58m
Multiple Airlines
Mon 8/37:20 pm
TYS
- MFE
2 stops45h 44m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$541
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:43 am
MFE
- TYS
1 stop11h 32m
Multiple Airlines
Sun 8/307:00 am
TYS
- MFE
2 stops37h 37m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$549
Best flights from McAllen to KnoxvilleDiscover carefully curated flight deals from McAllen to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
Discover carefully curated flight deals from McAllen to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2512:35 pm
MFE
- TYS
2 stops10h 09m
Delta
Mon 8/35:40 am
TYS
- MFE
2 stops7h 17m
Delta
Deal found 6/8![Delta logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/269:59 pm
MFE
- TYS
1 stop14h 58m
Multiple Airlines
Mon 8/37:20 pm
TYS
- MFE
2 stops45h 44m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$541
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:18 pm
MFE
- TYS
2 stops41h 28m
Allegiant Air
Sun 6/287:01 pm
TYS
- MFE
1 stop13h 53m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$558
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:00 am
MFE
- TYS
1 stop5h 20m
United Airlines
Fri 8/283:40 pm
TYS
- MFE
1 stop7h 19m
United Airlines
Deal found 6/10![United Airlines logo]()
$569
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:43 am
MFE
- TYS
1 stop11h 32m
Multiple Airlines
Sun 8/307:00 am
TYS
- MFE
2 stops37h 37m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:15 am
MFE
- TYS
1 stop11h 19m
United Airlines
Sat 10/312:00 pm
TYS
- MFE
2 stops9h 02m
United Airlines
Deal found 6/8![United Airlines logo]()
$635
Last-minute flights from McAllen to KnoxvilleDiscover last-minute flight deals from McAllen to Knoxville. Data last updated June 11, 2026 and is based on user searches.
Discover last-minute flight deals from McAllen to Knoxville. Data last updated June 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:39 am
MFE
- TYS
1 stop7h 52m
American Airlines
Tue 6/165:37 am
TYS
- MFE
1 stop5h 22m
American Airlines
Deal found 6/7![American Airlines logo]()
$509
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:18 pm
MFE
- TYS
1 stop27h 11m
Allegiant Air
Sun 6/287:01 pm
TYS
- MFE
1 stop13h 53m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$505
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:43 am
MFE
- TYS
1 stop11h 32m
Multiple Airlines
Sun 8/307:00 am
TYS
- MFE
2 stops37h 37m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:43 am
MFE
- TYS
1 stop10h 18m
Allegiant Air
Mon 8/32:47 pm
TYS
- MFE
1 stop26h 17m
Allegiant Air
Deal found 6/8![Allegiant Air logo]()
$439
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2512:35 pm
MFE
- TYS
2 stops10h 09m
Delta
Mon 8/35:40 am
TYS
- MFE
2 stops7h 17m
Delta
Deal found 6/8![Delta logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:43 am
MFE
- TYS
1 stop10h 18m
Multiple Airlines
Mon 8/37:20 pm
TYS
- MFE
2 stops45h 44m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:37 am
MFE
- TYS
1 stop7h 53m
American Airlines
Mon 8/38:11 pm
TYS
- MFE
1 stop5h 04m
American Airlines
Deal found 6/8![American Airlines logo]()
$540
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:20 am
MFE
- TYS
2 stops8h 28m
Delta
Mon 8/35:40 am
TYS
- MFE
2 stops7h 17m
Delta
Deal found 6/7![Delta logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/269:59 pm
MFE
- TYS
1 stop14h 58m
Allegiant Air
Mon 8/32:47 pm
TYS
- MFE
1 stop26h 17m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$523
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/269:59 pm
MFE
- TYS
1 stop14h 58m
Multiple Airlines
Mon 8/37:20 pm
TYS
- MFE
2 stops45h 44m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$541
One-way flights from McAllen to KnoxvilleSearch for one-way flight options from McAllen to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
Search for one-way flight options from McAllen to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:43 am
MFE
- TYS
1 stop11h 32m
Allegiant Air
Deal found 6/8![Allegiant Air logo]()
$140
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:47 pm
MFE
- TYS
2 stops9h 59m
Delta
Deal found 6/9![Delta logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:18 pm
MFE
- TYS
3 stops38h 53m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:20 am
MFE
- TYS
2 stops8h 28m
Delta
Deal found 6/9![Delta logo]()
$385
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:00 am
MFE
- TYS
2 stops12h 44m
United Airlines
Deal found 6/8![United Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:37 am
MFE
- TYS
1 stop7h 53m
American Airlines
Deal found 6/9![American Airlines logo]()
$447
Find flight deals from McAllen to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from McAllen (MFE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $439 (Kiwi.com) |
One-way from | $140 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $627 |
Cheapflights Fare Finder
Customize your flight search to find flights from McAllen to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from McAllen to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Sat 7/25
12:35 pm-11:44 pm
2 stops10h 09m
Knoxville McGhee Tyson
Mon 8/3
5:40 am-11:57 am
2 stops7h 17m
$456
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Sun 7/26
9:59 pm-1:57 pm
1 stop14h 58m
Knoxville McGhee Tyson
Mon 8/3
7:20 pm-4:04 pm
2 stops45h 44m
$541
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Fri 7/24
8:43 am-9:15 pm
1 stop11h 32m
Knoxville McGhee Tyson
Sun 8/30
7:00 am-7:37 pm
2 stops37h 37m
$549
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Wed 6/24
6:18 pm-12:46 pm
2 stops41h 28m
Knoxville McGhee Tyson
Sun 6/28
7:01 pm-7:54 am
1 stop13h 53m
$558
Quickest round-trip
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Mon 8/24
7:00 am-1:20 pm
1 stop5h 20m
Knoxville McGhee Tyson
Fri 8/28
3:40 pm-9:59 pm
1 stop7h 19m
$569
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Wed 10/28
7:15 am-7:34 pm
1 stop11h 19m
Knoxville McGhee Tyson
Sat 10/31
2:00 pm-10:02 pm
2 stops9h 02m
$635
Cheapest one-way
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Fri 7/10
8:43 am-9:15 pm
1 stop11h 32m
$140
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Fri 10/30
12:47 pm-11:46 pm
2 stops9h 59m
$170
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Fri 10/30
10:18 pm-2:11 pm
3 stops38h 53m
$279
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Fri 7/10
5:20 am-2:48 pm
2 stops8h 28m
$385
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from McAllen to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from McAllen to Knoxville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on McAllen-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on McAllen-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from McAllen-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on McAllen-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for McAllen-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from McAllen to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from McAllen with our price prediction graph.
MFE-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from McAllen to Knoxville
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 11, 2026.
Get a feel of what it's like to fly with American Airlines from McAllen to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Food
6.4
Boarding
7.5
Overall
7.1
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Entertainment
6.9
Food
6.4
Boarding
7.5
Overall
7.1
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from McAllen to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from McAllen
Popular flights
Alternative routes for McAllen to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from McAllen to Knoxville by cabin class
Find flights from McAllen to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 11, 2026.
McAllen and Knoxville flights
Browse other McAllen and Knoxville flight options. Last updated on June 11, 2026.
Other flights from McAllen
Browse through other flights departing from McAllen. Flights are based on user searches made on Cheapflights and were last updated on June 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from McAllen to Knoxville
Discover the top airline that operate flights from McAllen to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$324 | Average$508 | FlexibilityNo cancel fee | On-time71% |