$396+ Cheap flights from McAllen to Knoxville (MFE - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — TYS
Aug 22 — Aug 291
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from McAllen to Knoxville
Cheapest
Best
Last-minute
Cheapest flights from McAllen to KnoxvilleExplore the most affordable flight options available from McAllen to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from McAllen to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:37 am
MFE
- TYS
1 stop7h 53m
American Airlines
Thu 8/276:03 am
TYS
- MFE
1 stop5h 12m
American Airlines
Deal found 7/19![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:37 pm
MFE
- TYS
2 stops10h 15m
Delta
Thu 8/278:35 am
TYS
- MFE
2 stops9h 02m
Delta
Deal found 7/23![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am
MFE
- TYS
1 stop5h 20m
United Airlines
Wed 12/99:15 am
TYS
- MFE
1 stop9h 30m
United Airlines
Deal found 7/20![United Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:18 pm
MFE
- TYS
1 stop6h 00m
American Airlines
Mon 9/76:03 am
TYS
- MFE
1 stop5h 12m
American Airlines
Deal found 7/22![American Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:20 am
MFE
- TYS
2 stops10h 59m
Delta
Mon 9/75:40 am
TYS
- MFE
2 stops7h 17m
Delta
Deal found 7/22![Delta logo]()
$549
Best flights from McAllen to KnoxvilleDiscover carefully curated flight deals from McAllen to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from McAllen to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:37 am
MFE
- TYS
1 stop7h 53m
American Airlines
Thu 8/276:03 am
TYS
- MFE
1 stop5h 12m
American Airlines
Deal found 7/19![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:37 pm
MFE
- TYS
2 stops10h 15m
Delta
Thu 8/278:35 am
TYS
- MFE
2 stops9h 02m
Delta
Deal found 7/23![Delta logo]()
$409
Last-minute flights from McAllen to KnoxvilleDiscover last-minute flight deals from McAllen to Knoxville. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from McAllen to Knoxville. Data last updated July 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:37 am
MFE
- TYS
1 stop7h 53m
American Airlines
Thu 8/276:03 am
TYS
- MFE
1 stop5h 12m
American Airlines
Deal found 7/19![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:37 pm
MFE
- TYS
2 stops10h 15m
Delta
Thu 8/278:35 am
TYS
- MFE
2 stops9h 02m
Delta
Deal found 7/23![Delta logo]()
$409
Find flight deals from McAllen to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from McAllen (MFE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $396 (American Airlines) |
Popular in | January |
Cheapest in | March |
Average price | $531 |
Cheapflights Fare Finder
Customize your flight search to find flights from McAllen to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from McAllen to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Mon 8/3
10:37 am-7:30 pm
1 stop7h 53m
Knoxville McGhee Tyson
Thu 8/27
6:03 am-10:15 am
1 stop5h 12m
$396
McAllenKnoxville
MFE - TYS
MFETYS
McAllen Miller Intl
Mon 8/3
12:37 pm-11:52 pm
2 stops10h 15m
Knoxville McGhee Tyson
Thu 8/27
8:35 am-4:37 pm
2 stops9h 02m
$409
Sorted by cheapest first
Compare providers for flights from McAllen to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from McAllen to Knoxville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on McAllen-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on McAllen-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from McAllen-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on McAllen-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for McAllen-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from McAllen to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from McAllen with our price prediction graph.
MFE-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 23, 2026.
Get a feel of what it's like to fly with American Airlines from McAllen to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Crew
7.9
Comfort
7.2
Overall
7.1
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Boarding
7.5
Crew
7.9
Comfort
7.2
Overall
7.1
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from McAllen to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
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Top airline flying from McAllen to Knoxville
Discover the top airline that operate flights from McAllen to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$324 | Average$531 | FlexibilityNo cancel fee | On-time71% |