$176+ Cheap flights from Knoxville to McAllen (TYS - MFE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFE
Aug 16 — Aug 231
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to McAllen
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Best
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Cheapest flights from Knoxville to McAllenExplore the most affordable flight options available from Knoxville to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
Explore the most affordable flight options available from Knoxville to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
TYS
- MFE
1 stop7h 19m
United Airlines
Mon 8/242:08 pm
MFE
- TYS
1 stop6h 37m
United Airlines
Deal found 7/13![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:31 pm
TYS
- MFE
1 stop7h 44m
American Airlines
Mon 8/35:00 am
MFE
- TYS
1 stop6h 53m
American Airlines
Deal found 7/15![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:54 pm
TYS
- MFE
2 stops9h 05m
Delta
Mon 8/312:37 pm
MFE
- TYS
2 stops10h 15m
Delta
Deal found 7/15![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:15 pm
TYS
- MFE
1 stop5h 43m
United Airlines
Sun 11/17:25 pm
MFE
- TYS
1 stop25h 17m
United Airlines
Deal found 7/12![United Airlines logo]()
$583
Best flights from Knoxville to McAllenDiscover carefully curated flight deals from Knoxville to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
Discover carefully curated flight deals from Knoxville to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
TYS
- MFE
1 stop7h 19m
United Airlines
Mon 8/242:08 pm
MFE
- TYS
1 stop6h 37m
United Airlines
Deal found 7/13![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:31 pm
TYS
- MFE
1 stop7h 44m
American Airlines
Mon 8/35:00 am
MFE
- TYS
1 stop6h 53m
American Airlines
Deal found 7/15![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:54 pm
TYS
- MFE
2 stops9h 05m
Delta
Mon 8/312:37 pm
MFE
- TYS
2 stops10h 15m
Delta
Deal found 7/15![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:15 pm
TYS
- MFE
1 stop5h 43m
United Airlines
Sun 11/17:25 pm
MFE
- TYS
1 stop25h 17m
United Airlines
Deal found 7/12![United Airlines logo]()
$583
Last-minute flights from Knoxville to McAllenDiscover last-minute flight deals from Knoxville to McAllen. Data last updated July 17, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to McAllen. Data last updated July 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:31 pm
TYS
- MFE
1 stop7h 44m
American Airlines
Mon 8/35:00 am
MFE
- TYS
1 stop6h 53m
American Airlines
Deal found 7/15![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:54 pm
TYS
- MFE
2 stops9h 05m
Delta
Mon 8/312:37 pm
MFE
- TYS
2 stops10h 15m
Delta
Deal found 7/15![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
TYS
- MFE
1 stop7h 19m
United Airlines
Mon 8/242:08 pm
MFE
- TYS
1 stop6h 37m
United Airlines
Deal found 7/13![United Airlines logo]()
$409
One-way flights from Knoxville to McAllenSearch for one-way flight options from Knoxville to McAllen. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
Search for one-way flight options from Knoxville to McAllen. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:08 pm
TYS
- MFE
1 stop14h 21m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/91:33 pm
TYS
- MFE
1 stop20h 56m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:34 pm
TYS
- MFE
2 stops31h 00m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:56 pm
TYS
- MFE
1 stop18h 33m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:00 am
TYS
- MFE
2 stops29h 24m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$234
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:12 pm
TYS
- MFE
2 stops18h 45m
Delta
Deal found 7/12![Delta logo]()
$235
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:03 am
TYS
- MFE
1 stop5h 11m
American Airlines
Deal found 7/12![American Airlines logo]()
$260
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/104:38 pm
TYS
- MFE
2 stops8h 21m
Delta
Deal found 7/12![Delta logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:30 pm
TYS
- MFE
2 stops50h 29m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:03 am
TYS
- MFE
1 stop5h 12m
American Airlines
Deal found 7/12![American Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:33 pm
TYS
- MFE
1 stop5h 29m
American Airlines
Deal found 7/12![American Airlines logo]()
$348
Find flight deals from Knoxville to McAllen
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to McAllen (MFE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $409 (United Airlines) |
One-way from | $176 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
Use the filters below to find and compare flights from Knoxville to McAllen that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Fri 8/21
3:40 pm-9:59 pm
1 stop7h 19m
McAllen Miller Intl
Mon 8/24
2:08 pm-9:45 pm
1 stop6h 37m
$409
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Thu 7/30
5:31 pm-12:15 am
1 stop7h 44m
McAllen Miller Intl
Mon 8/3
5:00 am-12:53 pm
1 stop6h 53m
$414
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Thu 7/30
3:54 pm-11:59 pm
2 stops9h 05m
McAllen Miller Intl
Mon 8/3
12:37 pm-11:52 pm
2 stops10h 15m
$439
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Thu 10/29
5:15 pm-9:58 pm
1 stop5h 43m
McAllen Miller Intl
Sun 11/1
7:25 pm-9:42 pm
1 stop25h 17m
$583
Cheapest one-way
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Tue 8/11
6:12 pm-11:57 am
2 stops18h 45m
$235
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Mon 8/10
4:38 pm-11:59 pm
2 stops8h 21m
$265
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Sat 9/5
6:00 am-11:57 am
2 stops6h 57m
$265
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Fri 8/14
5:40 am-11:57 am
2 stops7h 17m
$265
Quickest one-way
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Wed 9/9
12:15 pm-3:59 pm
1 stop4h 44m
$305
KnoxvilleMcAllen
TYS - MFE
TYSMFE
Knoxville McGhee Tyson
Sun 9/6
7:15 am-1:27 pm
1 stop7h 12m
$305
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Knoxville to McAllen
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to McAllen in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-McAllen flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-McAllen flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-McAllen flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-McAllen flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-McAllen flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to McAllen
Have a flexible travel schedule? Discover the best time to fly to McAllen from Knoxville with our price prediction graph.
TYS-MFE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing McAllen
Get insights into the airlines that provide service to McAllen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to McAllen. Reviews last updated July 17, 2026.
Get a feel of what it's like to fly with American Airlines from Knoxville to McAllen by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Boarding
7.5
Overall
7.1
Food
6.4
Entertainment
6.8
Crew
7.9
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Comfort
7.2
Boarding
7.5
Overall
7.1
Food
6.4
Entertainment
6.8
Crew
7.9
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Related info for your journey
Find useful and relevant information for your journey from Knoxville to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near McAllen?
Book flights to McAllen if you plan to visit one of these locationsPharr
Weslaco
Mission
Edinburg
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Explore flights to McAllen departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 17, 2026.
Knoxville and McAllen flights
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Top airline flying from Knoxville to McAllen
Discover the top airline that operate flights from Knoxville to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$278 | Average$485 | FlexibilityNo cancel fee | On-time71% |