HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Medford

$424+ Cheap flights from Knoxville to Medford (TYS - MFR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFR
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Medford with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Medford

Cheapest flights from Knoxville to Medford
Explore the most affordable flight options available from Knoxville to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:20 pm
TYS
-
MFR
1 stop8h 11m
United Airlines
Mon 5/116:36 pm
MFR
-
TYS
2 stops12h 30m
United Airlines
Deal found 4/20$424
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:56 pm
TYS
-
MFR
1 stop7h 20m
United Airlines
Tue 8/255:00 am
MFR
-
TYS
1 stop7h 54m
United Airlines
Deal found 4/19$439
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:40 am
TYS
-
MFR
2 stops10h 20m
Delta
Mon 5/115:25 pm
MFR
-
TYS
2 stops13h 09m
Delta
Deal found 4/20$454
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:56 pm
TYS
-
MFR
1 stop7h 20m
United Airlines
Sat 9/51:08 pm
MFR
-
TYS
1 stop6h 30m
United Airlines
Deal found 4/19$483
This Alaska Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:46 pm
TYS
-
MFR
2 stops13h 13m
Alaska Airlines
Sat 9/56:58 pm
MFR
-
TYS
2 stops13h 16m
Alaska Airlines
Deal found 4/20$493
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:46 pm
TYS
-
MFR
2 stops12h 09m
Alaska Airlines
Tue 8/256:00 am
MFR
-
TYS
2 stops14h 18m
Alaska Airlines
Deal found 4/19$523
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:29 am
TYS
-
MFR
2 stops12h 19m
Delta
Fri 5/85:15 am
MFR
-
TYS
2 stops9h 12m
Delta
Deal found 4/23$539
This Alaska Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:46 pm
TYS
-
MFR
2 stops13h 18m
Alaska Airlines
Thu 8/206:00 am
MFR
-
TYS
2 stops14h 18m
Alaska Airlines
Deal found 4/20$569

Find flight deals from Knoxville to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$424
(United Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-Medford flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Medford flights.
Search Deals
From Knoxville McGhee Tyson to Medford
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Thu 8/20

4:56 pm-9:16 pm

1 stop7h 20m

Medford

Tue 8/25

5:00 am-3:54 pm

1 stop7h 54m

$439

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Thu 5/7

5:40 am-1:00 pm

2 stops10h 20m

Medford

Mon 5/11

5:25 pm-9:34 am

2 stops13h 09m

$454

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 8/28

4:56 pm-9:16 pm

1 stop7h 20m

Medford

Sat 9/5

6:26 pm-10:36 am

2 stops13h 10m

$488

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Thu 8/20

1:46 pm-10:55 pm

2 stops12h 09m

Medford

Tue 8/25

6:00 am-11:18 pm

2 stops14h 18m

$523

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

1:46 pm-12:04 am

2 stops13h 18m

Medford

Thu 8/20

6:00 am-11:18 pm

2 stops14h 18m

$601
Quickest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

8:48 am-1:00 pm

1 stop7h 12m

Medford

Thu 8/20

5:00 am-3:54 pm

1 stop7h 54m

$602

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/19

Sorted by cheapest first

Compare providers for flights from Knoxville to Medford

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Medford in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Medford flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Medford flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Medford flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Medford flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Medford flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown United Airlines from Knoxville to Medford. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,643 reviews

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,643 reviews
United Airlines
7.4
Good
9,643 reviews

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Medford?

    Airlines like United Airlines, Delta, and Alaska Airlines fly from Knoxville to Medford in about 7h 20m. The time it takes to get you to your destination can typically vary by up to 4h 49m. The distance from Knoxville to Medford is about 2113 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Medford round-trip?

    Cheapflights users have booked flights from Knoxville to Medford round-trip from $323.

  • Can I find deals for flights from Knoxville to Medford that include hotel bookings?

    Yes. In addition to deals on Knoxville to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Medford.

  • Can I find deals for business class flights from Knoxville to Medford?

    Yes. Cheapflights offers flight deals from Knoxville to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Yreka

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Knoxville to Medford

Discover the top airline that operate flights from Knoxville to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$323Average$762FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights