$451+ Cheap flights from Knoxville to Amarillo (TYS - AMA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — AMA
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Amarillo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Amarillo
Cheapest
Best
Last-minute
Cheapest flights from Knoxville to AmarilloExplore the most affordable flight options available from Knoxville to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Knoxville to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:02 pm -
1 stop4h 57m
Mon 10/124:20 pm -
1 stop5h 58m
Deal found 9/5![American Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:30 am -
1 stop5h 39m
Wed 9/166:00 am -
1 stop6h 53m
Deal found 9/5![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:49 am -
1 stop4h 51m
Mon 9/212:57 pm -
1 stop4h 55m
Deal found 9/2![American Airlines logo]()
$567
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:00 pm -
2 stops10h 10m
Mon 9/216:00 am -
1 stop6h 25m
Deal found 9/2![Southwest logo]()
$572
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
1 stop4h 50m
Sun 9/205:00 am -
1 stop5h 17m
Deal found 9/7![American Airlines logo]()
$619
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:10 am -
2 stops8h 10m
Sun 9/206:05 am -
2 stops5h 20m
Deal found 9/7![Southwest logo]()
$674
Best flights from Knoxville to AmarilloDiscover carefully curated flight deals from Knoxville to Amarillo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Knoxville to Amarillo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:02 pm -
1 stop4h 57m
Mon 10/124:20 pm -
1 stop5h 58m
Deal found 9/5![American Airlines logo]()
$451
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:00 pm -
2 stops10h 10m
Mon 9/216:00 am -
1 stop6h 25m
Deal found 9/2![Southwest logo]()
$572
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:49 am -
1 stop4h 51m
Mon 9/212:57 pm -
1 stop4h 55m
Deal found 9/2![American Airlines logo]()
$567
Last-minute flights from Knoxville to AmarilloDiscover last-minute flight deals from Knoxville to Amarillo. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Amarillo. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
1 stop4h 50m
Sun 9/205:00 am -
1 stop5h 17m
Deal found 9/7![American Airlines logo]()
$619
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:10 am -
2 stops8h 10m
Sun 9/206:05 am -
2 stops5h 20m
Deal found 9/7![Southwest logo]()
$674
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:30 am -
1 stop5h 39m
Wed 9/166:00 am -
1 stop6h 53m
Deal found 9/5![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:49 am -
1 stop4h 51m
Mon 9/212:57 pm -
1 stop4h 55m
Deal found 9/2![American Airlines logo]()
$567
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:00 pm -
2 stops10h 10m
Mon 9/216:00 am -
1 stop6h 25m
Deal found 9/2![Southwest logo]()
$572
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:02 pm -
1 stop4h 57m
Mon 10/124:20 pm -
1 stop5h 58m
Deal found 9/5![American Airlines logo]()
$451
Find flight deals from Knoxville to Amarillo
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Amarillo (AMA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $451 (American Airlines) |
Popular in | January |
Cheapest in | July |
Average price | $566 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Knoxville to Amarillo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleAmarillo
TYS Knoxville McGhee Tyson - AMA Amarillo
TYSAMA
Knoxville McGhee Tyson
Mon 10/5
8:02 pm-11:59 pm
1 stop4h 57m
Amarillo
Mon 10/12
4:20 pm-11:18 pm
1 stop5h 58m
$451
Quickest round-trip
KnoxvilleAmarillo
TYS Knoxville McGhee Tyson - AMA Amarillo
TYSAMA
Knoxville McGhee Tyson
Thu 9/17
11:49 am-3:40 pm
1 stop4h 51m
Amarillo
Mon 9/21
2:57 pm-8:52 pm
1 stop4h 55m
$567
KnoxvilleAmarillo
TYS Knoxville McGhee Tyson - AMA Amarillo
TYSAMA
Knoxville McGhee Tyson
Thu 9/17
1:00 pm-10:10 pm
2 stops10h 10m
Amarillo
Mon 9/21
6:00 am-1:25 pm
1 stop6h 25m
$572
Sorted by cheapest first
Compare providers for flights from Knoxville to Amarillo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Amarillo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Amarillo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Amarillo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Amarillo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Amarillo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Amarillo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Amarillo
Have a flexible travel schedule? Discover the best time to fly to Amarillo from Knoxville with our price prediction graph.
TYS-AMA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Amarillo
Get insights into the airlines that provide service to Amarillo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Amarillo. Reviews last updated September 7, 2026.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Amarillo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Crew
7.9
Boarding
7.5
Food
6.4
Comfort
7.2
Entertainment
6.8
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Overall
7.1
Crew
7.9
Boarding
7.5
Food
6.4
Comfort
7.2
Entertainment
6.8
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Amarillo?
Book flights to Amarillo if you plan to visit one of these locationsDalhart
Dumas
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Top airline flying from Knoxville to Amarillo
Discover the top airline that operate flights from Knoxville to Amarillo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$309 | Average$556 | FlexibilityNo cancel fee | On-time71% |