$81+ Cheap flights from Knoxville (TYS) to Houston
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — HOU
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Houston are usually found in June or October, booked 72 days in advance, depart on a Saturday or Wednesday and return on a Saturday
Cheap flight deals from Knoxville to Houston
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Cheapest flights from Knoxville to HoustonExplore the most affordable flight options available from Knoxville to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Knoxville to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:28 pm -
Nonstop2h 17m
Mon 10/195:04 pm -
Nonstop2h 04m
Deal found 9/14![Allegiant Air logo]()
$118
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:31 pm -
Nonstop2h 20m
Mon 9/284:27 pm -
Nonstop2h 07m
Deal found 9/17![Allegiant Air logo]()
$122
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:57 pm -
Nonstop2h 17m
Mon 10/57:19 pm -
Nonstop2h 04m
Deal found 9/16![Allegiant Air logo]()
$152
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:28 pm -
Nonstop2h 17m
Fri 10/305:01 pm -
Nonstop2h 04m
Deal found 9/16![Allegiant Air logo]()
$153
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:54 pm -
Nonstop2h 17m
Mon 10/263:51 pm -
Nonstop2h 04m
Deal found 9/17![Allegiant Air logo]()
$157
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:44 pm -
Nonstop2h 17m
Fri 10/305:01 pm -
Nonstop2h 04m
Deal found 9/15![Allegiant Air logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:54 pm -
Nonstop2h 17m
Mon 11/23:51 pm -
Nonstop2h 04m
Deal found 9/15![Allegiant Air logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
1 stop18h 20m
Sat 10/316:05 am -
2 stops35h 28m
Deal found 9/15![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:44 pm -
Nonstop2h 17m
Mon 11/23:51 pm -
Nonstop2h 04m
Deal found 9/15![Allegiant Air logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
1 stop18h 20m
Thu 10/296:05 am -
2 stops14h 51m
Deal found 9/15![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:55 am -
1 stop6h 49m
Wed 11/118:21 pm -
2 stops24h 44m
Deal found 9/15![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:14 pm -
1 stop23h 47m
Wed 10/216:05 am -
2 stops28h 24m
Deal found 9/13![Multiple Airlines logo]()
$221
Best flights from Knoxville to HoustonDiscover carefully curated flight deals from Knoxville to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Knoxville to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
1 stop6h 00m
Mon 10/263:00 pm -
2 stops6h 45m
Deal found 9/16![Southwest logo]()
$272
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:17 pm -
1 stop6h 15m
Thu 12/1710:41 am -
1 stop5h 49m
Deal found 9/13![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:45 pm -
Nonstop2h 25m
Wed 10/288:00 am -
Nonstop2h 12m
Deal found 9/15![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/63:40 pm -
1 stop5h 00m
Tue 12/811:30 am -
2 stops7h 15m
Deal found 9/13![Southwest logo]()
$287
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:05 am -
2 stops8h 05m
Sun 11/2212:15 pm -
2 stops7h 20m
Deal found 9/16![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:40 am -
1 stop5h 28m
Tue 10/136:09 am -
1 stop6h 31m
Deal found 9/14![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:23 pm -
1 stop5h 40m
Sat 10/246:09 am -
1 stop6h 22m
Deal found 9/13![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:25 pm -
1 stop6h 10m
Sun 11/812:15 pm -
2 stops7h 20m
Deal found 9/16![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:59 am -
Nonstop2h 36m
Tue 11/36:40 pm -
Nonstop2h 17m
Deal found 9/14![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:07 pm -
1 stop6h 14m
Sun 11/156:00 am -
1 stop4h 28m
Deal found 9/17![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:15 pm -
1 stop6h 35m
Thu 12/1711:30 am -
2 stops8h 00m
Deal found 9/17![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:23 pm -
1 stop6h 32m
Sun 11/15:35 am -
1 stop4h 10m
Deal found 9/13![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:22 pm -
1 stop5h 37m
Sun 11/155:35 am -
1 stop4h 53m
Deal found 9/16![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:40 am -
1 stop4h 18m
Thu 12/1712:30 pm -
1 stop4h 00m
Deal found 9/16![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:01 pm -
1 stop7h 06m
Sat 1/168:00 am -
1 stop6h 05m
Deal found 9/14![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:40 am -
1 stop3h 55m
Tue 10/137:00 am -
1 stop5h 40m
Deal found 9/14![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:22 pm -
1 stop5h 37m
Sun 11/155:35 am -
1 stop4h 53m
Deal found 9/13![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:45 pm -
1 stop5h 10m
Sun 11/15:35 am -
1 stop4h 10m
Deal found 9/15![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:23 pm -
1 stop4h 14m
Fri 10/306:20 pm -
1 stop15h 33m
Deal found 9/15![Delta logo]()
$372
Last-minute flights from Knoxville to HoustonDiscover last-minute flight deals from Knoxville to Houston. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Houston. Data last updated September 17, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:31 pm -
Nonstop2h 20m
Mon 9/284:27 pm -
Nonstop2h 07m
Deal found 9/17![Allegiant Air logo]()
$122
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:57 pm -
Nonstop2h 17m
Mon 10/57:19 pm -
Nonstop2h 04m
Deal found 9/16![Allegiant Air logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:14 pm -
1 stop23h 47m
Wed 10/216:05 am -
2 stops28h 24m
Deal found 9/13![Multiple Airlines logo]()
$221
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:28 pm -
Nonstop2h 17m
Mon 10/195:04 pm -
Nonstop2h 04m
Deal found 9/14![Allegiant Air logo]()
$118
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:28 pm -
Nonstop2h 17m
Fri 10/305:01 pm -
Nonstop2h 04m
Deal found 9/16![Allegiant Air logo]()
$153
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:54 pm -
Nonstop2h 17m
Mon 10/263:51 pm -
Nonstop2h 04m
Deal found 9/17![Allegiant Air logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:54 pm -
Nonstop2h 17m
Mon 11/23:51 pm -
Nonstop2h 04m
Deal found 9/15![Allegiant Air logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
1 stop18h 20m
Sat 10/316:05 am -
2 stops35h 28m
Deal found 9/15![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
1 stop18h 20m
Thu 10/296:05 am -
2 stops14h 51m
Deal found 9/15![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
1 stop18h 20m
Tue 10/278:18 am -
1 stop7h 56m
Deal found 9/15![Multiple Airlines logo]()
$236
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:44 pm -
Nonstop2h 17m
Fri 10/305:01 pm -
Nonstop2h 04m
Deal found 9/15![Allegiant Air logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:44 pm -
Nonstop2h 17m
Mon 11/23:51 pm -
Nonstop2h 04m
Deal found 9/15![Allegiant Air logo]()
$209
One-way flights from Knoxville to HoustonSearch for one-way flight options from Knoxville to Houston. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Knoxville to Houston. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:44 pm -
Nonstop2h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Allegiant Air logo]()
$81
This Super.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:57 pm -
Nonstop2h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$82
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:12 pm -
Nonstop2h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$92
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:28 pm -
Nonstop2h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:12 pm -
2 stops33h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:06 pm -
Nonstop2h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Allegiant Air logo]()
$111
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:15 pm -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:58 pm -
2 stops36h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$121
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:25 pm -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
2 stops49h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:04 pm -
1 stop22h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$140
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:30 pm -
1 stop9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$141
Find flight deals from Knoxville to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Round-trip from | $118 (CheapOair) |
|---|---|
One-way from | $81 (Booking.com) |
Popular in | March |
Cheapest in | June |
Average price | $309 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Knoxville to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Mon 11/2
7:25 pm-12:30 am
1 stop6h 05m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$126
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Fri 10/23
5:30 pm-1:55 am
1 stop9h 25m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$141
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Thu 11/26
6:45 am-1:55 pm
2 stops8h 10m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$175
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Mon 10/5
7:25 pm-12:25 am
1 stop6h 00m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$190
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Tue 9/29
3:00 pm-11:15 pm
1 stop9h 15m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$190
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Wed 12/9
5:30 am-11:05 am
1 stop6h 35m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Wed 10/14
8:02 pm-11:49 pm
1 stop4h 47m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
KnoxvilleHouston
TYS Knoxville McGhee Tyson - IAH Houston George Bush Intcntl
TYSIAH
Knoxville McGhee Tyson
Fri 11/13
5:32 pm-10:39 pm
1 stop6h 07m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
KnoxvilleHouston
TYS Knoxville McGhee Tyson - IAH Houston George Bush Intcntl
TYSIAH
Knoxville McGhee Tyson
Thu 12/10
8:33 am-2:08 pm
1 stop6h 35m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Sat 9/26
12:30 pm-6:35 pm
1 stop7h 05m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$225
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Knoxville with our price prediction graph.
TYS-HO1
TYS-HOU
TYS-IAH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Houston
TYS-HO1
TYS-HOU
TYS-IAH
What is the cheapest month to book a flight from Knoxville to Houston?
Currently, June is the cheapest month in which you can book a flight from Knoxville to Houston (average of $212). Flying from Knoxville to Houston in November is currently the most expensive (average of $431). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to HOU?
Find hourly flight availability from Knoxville to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
When flying from Knoxville to Houston, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Knoxville to Houston?
Airfare is below average for this route at the moment.
Knoxville to Houston flights typically cost between $288 and $379 in October.The cheapest round-trip price found within the last 5 days was $118 on Allegiant Air (Oct 16-Oct 19).
How far ahead should I book a flight from Knoxville to Houston?
The best time to book flights from Knoxville to Houston is 63 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated September 17, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Knoxville and Houston flights
Browse other Knoxville and Houston flight options. Last updated on September 17, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Knoxville to Houston
Discover the top 5 airlines that operate flights from Knoxville to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$133 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$209 | Average$382 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$229 | Average$354 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$260 | Average$348 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$269 | Average$313 | FlexibilityNo cancel fee | On-timeN/A |