$73+ Cheap flights from Knoxville (TYS) to Houston
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — HOU
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Houston are usually found in June or December, booked 72 days in advance, depart on a Monday or Wednesday and return on a Saturday
Cheap flight deals from Knoxville to Houston
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Cheapest flights from Knoxville to HoustonExplore the most affordable flight options available from Knoxville to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Knoxville to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:49 pm -
Nonstop2h 20m
Mon 11/95:09 pm -
Nonstop2h 07m
Deal found 10/27![Allegiant Air logo]()
$104
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:12 pm -
Nonstop2h 23m
Mon 11/232:59 pm -
Nonstop2h 02m
Deal found 10/25![Allegiant Air logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:14 pm -
1 stop23h 46m
Sun 12/65:01 pm -
1 stop14h 26m
Deal found 10/29![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
2 stops29h 34m
Wed 12/25:01 pm -
1 stop26h 09m
Deal found 10/28![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:52 pm -
1 stop19h 50m
Wed 1/65:06 pm -
1 stop26h 34m
Deal found 10/28![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
2 stops39h 23m
Tue 11/178:18 am -
1 stop8h 00m
Deal found 10/27![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:55 am -
1 stop6h 49m
Tue 11/178:18 am -
1 stop8h 00m
Deal found 10/27![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:30 am -
1 stop15h 27m
Mon 1/46:27 pm -
1 stop23h 49m
Deal found 10/25![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:58 pm -
2 stops28h 31m
Mon 12/145:01 pm -
1 stop19h 06m
Deal found 10/25![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:00 pm -
1 stop20h 06m
Sat 1/163:27 pm -
1 stop16h 03m
Deal found 10/27![Multiple Airlines logo]()
$244
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 pm -
1 stop6h 04m
Tue 12/86:00 am -
1 stop7h 02m
Deal found 10/29![American Airlines logo]()
$245
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:55 pm -
1 stop4h 47m
Tue 12/87:00 am -
1 stop6h 02m
Deal found 10/29![American Airlines logo]()
$245
Best flights from Knoxville to HoustonDiscover carefully curated flight deals from Knoxville to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Knoxville to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:15 pm -
1 stop6h 45m
Sat 12/56:05 am -
1 stop7h 05m
Deal found 10/29![Southwest logo]()
$265
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:57 am -
Nonstop2h 48m
Mon 1/43:39 pm -
Nonstop2h 10m
Deal found 10/25![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:01 pm -
1 stop7h 05m
Mon 12/146:28 pm -
1 stop4h 29m
Deal found 10/25![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:15 pm -
1 stop6h 45m
Fri 12/112:45 pm -
1 stop4h 50m
Deal found 10/29![Southwest logo]()
$285
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:15 pm -
1 stop6h 40m
Sat 12/511:05 am -
2 stops5h 35m
Deal found 10/30![Southwest logo]()
$308
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:53 am -
Nonstop2h 40m
Sun 1/176:40 pm -
Nonstop2h 19m
Deal found 10/28![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:45 am -
2 stops8h 15m
Sat 1/166:10 am -
2 stops10h 10m
Deal found 10/29![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:34 pm -
1 stop5h 43m
Sat 11/285:35 am -
1 stop4h 53m
Deal found 10/26![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/156:25 pm -
1 stop4h 15m
Mon 1/1811:00 am -
1 stop5h 45m
Deal found 10/28![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:00 pm -
1 stop5h 11m
Sat 11/1412:32 pm -
1 stop3h 50m
Deal found 10/27![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:45 am -
1 stop4h 35m
Wed 12/210:30 am -
2 stops8h 20m
Deal found 10/25![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
Nonstop2h 40m
Mon 12/146:40 pm -
Nonstop2h 17m
Deal found 10/25![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:45 am -
2 stops8h 25m
Mon 1/1111:15 am -
2 stops6h 20m
Deal found 10/25![Southwest logo]()
$329
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:05 am -
Nonstop2h 40m
Sun 12/63:05 pm -
Nonstop2h 13m
Deal found 10/26![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
Nonstop2h 40m
Sun 12/138:00 am -
Nonstop2h 12m
Deal found 10/25![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:45 pm -
1 stop6h 20m
Tue 12/221:45 pm -
1 stop7h 55m
Deal found 10/29![Southwest logo]()
$336
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
2 stops7h 50m
Sun 1/1711:10 am -
2 stops6h 25m
Deal found 10/28![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:45 pm -
Nonstop2h 37m
Tue 11/176:40 pm -
Nonstop2h 17m
Deal found 10/27![United Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
Nonstop2h 40m
Thu 12/176:25 pm -
Nonstop2h 19m
Deal found 10/26![United Airlines logo]()
$484
Last-minute flights from Knoxville to HoustonDiscover last-minute flight deals from Knoxville to Houston. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Houston. Data last updated October 30, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:49 pm -
Nonstop2h 20m
Mon 11/95:09 pm -
Nonstop2h 07m
Deal found 10/27![Allegiant Air logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:55 am -
2 stops11h 58m
Tue 11/178:18 am -
1 stop8h 00m
Deal found 10/27![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:55 am -
1 stop6h 49m
Tue 11/178:18 am -
1 stop8h 00m
Deal found 10/27![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:55 am -
1 stop6h 49m
Sat 11/148:18 am -
2 stops26h 05m
Deal found 10/27![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:37 pm -
1 stop22h 07m
Sun 11/158:35 pm -
1 stop15h 56m
Deal found 10/25![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
2 stops39h 23m
Tue 11/178:18 am -
1 stop8h 00m
Deal found 10/27![Multiple Airlines logo]()
$207
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:59 pm -
Nonstop2h 20m
Fri 11/208:25 pm -
Nonstop2h 02m
Deal found 10/27![Allegiant Air logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:39 pm -
1 stop18h 35m
Thu 11/194:49 pm -
1 stop18h 53m
Deal found 10/26![Multiple Airlines logo]()
$276
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:12 pm -
Nonstop2h 23m
Mon 11/232:59 pm -
Nonstop2h 02m
Deal found 10/25![Allegiant Air logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:40 am -
1 stop28h 02m
Tue 12/15:01 pm -
1 stop22h 23m
Deal found 10/27![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
2 stops29h 34m
Wed 12/25:01 pm -
1 stop26h 09m
Deal found 10/28![Multiple Airlines logo]()
$204
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:45 am -
1 stop4h 35m
Wed 12/27:35 am -
1 stop3h 45m
Deal found 10/25![Southwest logo]()
$312
One-way flights from Knoxville to HoustonSearch for one-way flight options from Knoxville to Houston. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Knoxville to Houston. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:49 pm -
Nonstop2h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Allegiant Air logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:49 pm -
1 stop27h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/249:08 pm -
1 stop20h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:52 pm -
1 stop19h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:55 am -
1 stop6h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:55 am -
1 stop28h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:55 am -
1 stop6h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$126
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:05 am -
1 stop4h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$133
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:30 am -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:55 am -
1 stop28h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$135
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:30 am -
1 stop4h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:25 pm -
1 stop6h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Southwest logo]()
$200
Find flight deals from Knoxville to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Round-trip from | $136 (CheapOair) |
|---|---|
One-way from | $73 (CheapOair) |
Popular in | March |
Cheapest in | June |
Average price | $294 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Knoxville to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleHouston
TYS Knoxville McGhee Tyson - IAH Houston George Bush Intcntl
TYSIAH
Knoxville McGhee Tyson
Wed 11/4
10:55 am-2:44 pm
1 stop28h 49m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$125
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Tue 12/8
7:05 am-10:25 am
1 stop4h 20m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$133
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Thu 11/19
7:05 am-2:10 pm
2 stops8h 05m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$138
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Thu 12/10
5:30 am-9:28 am
1 stop4h 58m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$180
KnoxvilleHouston
TYS Knoxville McGhee Tyson - IAH Houston George Bush Intcntl
TYSIAH
Knoxville McGhee Tyson
Fri 11/13
2:38 pm-2:44 pm
1 stop25h 06m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$196
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Wed 11/11
7:05 am-10:25 am
1 stop4h 20m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$200
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Tue 11/10
4:15 pm-9:55 pm
1 stop6h 40m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$200
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Thu 11/12
7:25 pm-12:35 am
1 stop6h 10m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$200
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Fri 11/13
5:25 pm-11:55 pm
1 stop7h 30m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$200
KnoxvilleHouston
TYS Knoxville McGhee Tyson - HOU Houston Hobby
TYSHOU
Knoxville McGhee Tyson
Wed 12/9
6:52 am-1:29 pm
1 stop7h 37m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$205
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Knoxville with our price prediction graph.
TYS-HO1
TYS-HOU
TYS-IAH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Houston
TYS-HO1
TYS-HOU
TYS-IAH
What is the cheapest month to book a flight from Knoxville to Houston?
Currently, June is the cheapest month in which you can book a flight from Knoxville to Houston (average of $212). Flying from Knoxville to Houston in October is currently the most expensive (average of $451). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to HOU?
Find hourly flight availability from Knoxville to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
When flying from Knoxville to Houston, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Knoxville to Houston?
Airfare is below average for this route at the moment.
Knoxville to Houston flights typically cost between $342 and $459 in November.The cheapest round-trip price found within the last 5 days was $136 on Allegiant Air (Nov 20-Nov 23).
How far ahead should I book a flight from Knoxville to Houston?
The best time to book flights from Knoxville to Houston is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated October 30, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Knoxville and Houston flights
Browse other Knoxville and Houston flight options. Last updated on October 30, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
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Top 5 airlines flying from Knoxville to Houston
Discover the top 5 airlines that operate flights from Knoxville to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$143 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$209 | Average$407 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$229 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$260 | Average$353 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$269 | Average$313 | FlexibilityNo cancel fee | On-timeN/A |