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$292+ Cheap flights from Amarillo to Knoxville (AMA - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Amarillo to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Amarillo (AMA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$292
(American Airlines)

Popular in

August

Cheapest in

January

Average price

$309
From Amarillo to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Amarillo to Knoxville

Cheapest flights from Amarillo to Knoxville
Explore the most affordable flight options available from Amarillo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:48 pmAMA - TYS
1 stop4h 33mAmerican Airlines
Fri 10/106:22 pmTYS - AMA
1 stop6h 35mAmerican Airlines
Deal found 9/10$292
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:06 pmAMA - TYS
2 stops8h 44mAmerican Airlines
Sat 10/116:00 amTYS - AMA
1 stop4h 46mAmerican Airlines
Deal found 9/11$297
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/18:00 amAMA - TYS
2 stops12h 11mUnited Airlines
Thu 10/27:00 amTYS - AMA
2 stops10h 52mUnited Airlines
Deal found 9/11$360
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:26 pmAMA - TYS
1 stop6h 55mAmerican Airlines
Thu 10/25:30 amTYS - AMA
1 stop5h 16mAmerican Airlines
Deal found 9/11$361
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/49:10 amAMA - TYS
2 stops12h 40mUnited Airlines
Fri 10/107:26 pmTYS - AMA
2 stops19h 43mUnited Airlines
Deal found 9/11$425
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:27 pmAMA - TYS
2 stops16h 02mUnited Airlines
Sat 10/118:50 amTYS - AMA
2 stops9h 02mUnited Airlines
Deal found 9/11$430
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:48 pmAMA - TYS
1 stop4h 33mAmerican Airlines
Tue 9/166:00 amTYS - AMA
1 stop4h 44mAmerican Airlines
Deal found 9/9$463

Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Amarillo to Knoxville that are best for you.

Fly from

Amarillo

Fly to

Knoxville

Route

Depart

Return

Price

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Mon 10/6

6:02 am-11:44 am

1 stop4h 42m

Knoxville McGhee Tyson

Sat 10/11

6:00 am-9:46 am

1 stop4h 46m

$292

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Sat 10/4

6:48 pm-12:21 am

1 stop4h 33m

Knoxville McGhee Tyson

Fri 10/10

6:22 pm-11:57 pm

1 stop6h 35m

$292

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Wed 10/1

8:00 am-9:11 pm

2 stops12h 11m

Knoxville McGhee Tyson

Thu 10/2

9:30 am-2:09 pm

1 stop5h 39m

$297

AmarilloKnoxville

AMA - TYS

AMATYS

Amarillo

Wed 10/1

4:26 pm-12:21 am

1 stop6h 55m

Knoxville McGhee Tyson

Thu 10/2

5:30 am-9:46 am

1 stop5h 16m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Amarillo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to Knoxville

What is the cheapest month to book a flight from Amarillo to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Amarillo to Knoxville (average of $294). Flying from Amarillo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown American Airlines from Amarillo to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Amarillo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Amarillo to Knoxville?

    For as low as $292, American Airlines can have you in Knoxville from Amarillo in 4h 42m. Airlines will cover a distance of 995 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Amarillo to Knoxville round-trip?

    American Airlines, at $258, was found to be the cheapest airline from Amarillo to Knoxville.. This flight start at 28% lower than the current average price 3 months from now.

  • Can I find deals for flights from Amarillo to Knoxville that include hotel bookings?

    Yes. In addition to deals on Amarillo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to Knoxville.

  • Can I find deals for business class flights from Amarillo to Knoxville?

    Yes. Cheapflights offers flight deals from Amarillo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Amarillo to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Amarillo to Knoxville (average of $294). Flying from Amarillo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top airline flying from Amarillo to Knoxville

Discover the top airline that operate flights from Amarillo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$329FlexibilityNo cancel feeOn-time71%

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