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Key West

$104+ Cheap flights from South Carolina to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from South Carolina to Key West

Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated June 12, 2025.

Round-trip from

$161
(Kiwi.com)

One-way from

$104
(Kiwi.com)

Popular in

March

Cheapest in

June

Average price

$368
From South Carolina to Key West
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One-way flight from South Carolina to Key West
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Highest demand for flights based on searches. 11% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from South Carolina to Key West

Cheapest flights from South Carolina to Key West
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/139:05 pmCHS - EYW
1 stop13h 14mBreeze Airways
Wed 9/179:47 amEYW - CHS
1 stop5h 37mBreeze Airways
Deal found 6/11$160
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2211:03 amGSP - EYW
1 stop22h 19mBreeze Airways
Tue 7/2910:02 amEYW - GSP
1 stop4h 52mBreeze Airways
Deal found 6/9$188
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/11:25 pmMYR - EYW
1 stop6h 14mDelta
Thu 7/106:27 pmEYW - MYR
1 stop5h 32mDelta
Deal found 6/10$224
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/17:00 amMYR - EYW
1 stop7h 08mAmerican Airlines
Thu 7/1011:18 amEYW - MYR
2 stops6h 08mAmerican Airlines
Deal found 6/10$229
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/289:42 amCHS - EYW
2 stops22h 21mMultiple Airlines
Wed 7/23:33 pmEYW - CHS
1 stop23h 03mMultiple Airlines
Deal found 6/11$242
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:00 amGSP - EYW
1 stop4h 53mAmerican Airlines
Mon 9/227:31 pmEYW - GSP
1 stop4h 25mAmerican Airlines
Deal found 6/10$249
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/201:43 pmCAE - EYW
1 stop6h 06mDelta
Wed 7/307:00 amEYW - CAE
1 stop5h 53mDelta
Deal found 6/10$249
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:30 amMYR - EYW
1 stop9h 21mMultiple Airlines
Sun 8/248:53 amEYW - MYR
2 stops30h 15mMultiple Airlines
Deal found 6/11$252
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:24 amCAE - EYW
2 stops7h 09mAmerican Airlines
Wed 11/125:26 pmEYW - CAE
1 stop6h 14mAmerican Airlines
Deal found 6/10$254
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/81:45 pmCLT - EYW
1 stop25h 20mMultiple Airlines
Tue 7/1510:02 amEYW - CLT
1 stop7h 57mMultiple Airlines
Deal found 6/10$264
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/129:51 pmMYR - EYW
1 stop13h 50mAllegiant Air
Sat 7/193:58 pmEYW - MYR
2 stops27h 52mAllegiant Air
Deal found 6/12$287
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/292:15 pmGSP - EYW
1 stop5h 57mDelta
Tue 9/27:00 amEYW - GSP
1 stop6h 20mDelta
Deal found 6/10$304

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

Fly from

South Carolina

Fly to

Key West

Route

Depart

Return

Price

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Mon 7/7

9:31 pm-9:22 am

1 stop11h 51m

Key West

Mon 7/14

1:47 pm-8:28 am

1 stop18h 41m

$161

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Tue 7/22

11:03 am-9:22 am

1 stop22h 19m

Key West

Tue 7/29

10:02 am-2:54 pm

1 stop4h 52m

$188

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 7/1

1:25 pm-7:39 pm

1 stop6h 14m

Key West

Thu 7/10

6:27 pm-11:59 pm

1 stop5h 32m

$224

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 7/1

7:00 am-2:08 pm

1 stop7h 08m

Key West

Thu 7/10

11:18 am-5:26 pm

2 stops6h 08m

$229

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sat 6/28

9:42 am-8:03 am

2 stops22h 21m

Key West

Wed 7/2

3:33 pm-2:36 pm

1 stop23h 03m

$242

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sun 7/20

1:43 pm-7:49 pm

1 stop6h 06m

Key West

Wed 7/30

7:00 am-12:53 pm

1 stop5h 53m

$249

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 8/22

7:30 am-4:51 pm

1 stop9h 21m

Key West

Sun 8/24

8:53 am-3:08 pm

2 stops30h 15m

$252

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Tue 7/8

1:45 pm-3:05 pm

1 stop25h 20m

Key West

Tue 7/15

10:02 am-5:59 pm

1 stop7h 57m

$264

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Thu 8/21

11:05 am-7:07 pm

2 stops8h 02m

Key West

Sun 8/24

7:40 pm-11:35 pm

1 stop3h 55m

$284

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 7/12

9:51 pm-11:41 am

1 stop13h 50m

Key West

Sat 7/19

3:58 pm-7:50 pm

2 stops27h 52m

$287

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 51 results
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Best time to book a flight from South Carolina to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Key West

What is the cheapest month to book a flight from South Carolina to Key West?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to EYW?

Find hourly flight availability from South Carolina to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Key West as you normally would.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated June 12, 2025.
See what other customers who have flown with Breeze Airways, Delta and United Airlines from South Carolina to Key West have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Comfort

8.2

Overall

8.1

Entertainment

6.6

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
178 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Comfort

8.2

Overall

8.1

Entertainment

6.6

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,950 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Comfort

8.2

Overall

8.1

Entertainment

6.6

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,790 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Comfort

8.2

Overall

8.1

Entertainment

6.6

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Allegiant Air
7.3
Good
725 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Comfort

8.2

Overall

8.1

Entertainment

6.6

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
American Airlines
7.2
Good
10,000 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Comfort

8.2

Overall

8.1

Entertainment

6.6

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from South Carolina?

    For a flight from South Carolina to Key West, you will be flying into Key West. Key West (EYW) is just 2.6 mi from the center of the city.

  • What are the cheapest airlines to fly from South Carolina to Key West one-way?

    $104 is the cheapest one-way deal found within the past few days, from Breeze Airways. You may also be able to find cheap deals on Allegiant Air and Delta, with prices starting from $114 and $213, respectively.

  • What are the most popular routes from South Carolina to Key West?

    When deciding which route to take from South Carolina to Key West consider Charlotte Douglas - Key West, Charleston - Key West or Savannah/Hilton Head - Key West as they are the most popular.

  • Can I find deals for flights from South Carolina to Key West that include hotel bookings?

    Yes. In addition to deals on South Carolina to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Key West.

  • Can I find deals for business class flights from South Carolina to Key West?

    Yes. Cheapflights offers flight deals from South Carolina to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Key West?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Key West

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Key West

Discover the top 2 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$416FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$483FlexibilityNo cancel feeOn-time71%

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