HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key West

$114+ Cheap flights from South Carolina to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Key West with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Key West

Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$199
(Kiwi.com)

One-way from

$114
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$408
Provider with most accurate pricing for Myrtle Beach Intl-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Key West flights.
Search Deals
From South Carolina to Key West
Search Deals
One-way flight from South Carolina to Key West
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from South Carolina to Key West

Cheapest flights from South Carolina to Key West
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/249:36 pmCHS - EYW
1 stop11h 46mBreeze Airways
Thu 7/311:47 pmEYW - CHS
1 stop20h 43mBreeze Airways
Deal found 4/30$199
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/304:47 pmGSP - EYW
1 stop15h 20mBreeze Airways
Mon 11/108:47 amEYW - GSP
1 stop9h 59mBreeze Airways
Deal found 4/30$234
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:42 pmGSP - EYW
1 stop4h 02mDelta
Mon 9/292:35 pmEYW - GSP
1 stop6h 46mDelta
Deal found 4/29$249
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:00 amCLT - EYW
1 stop6h 08mDelta
Tue 10/146:00 pmEYW - CLT
1 stop4h 20mDelta
Deal found 4/30$257
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:24 pmMYR - EYW
1 stop6h 43mDelta
Mon 5/197:00 amEYW - MYR
1 stop5h 29mDelta
Deal found 4/30$259
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:00 amMYR - EYW
1 stop7h 10mAmerican Airlines
Tue 6/35:24 pmEYW - MYR
1 stop5h 07mAmerican Airlines
Deal found 4/30$274
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/43:10 pmCAE - EYW
1 stop4h 39mDelta
Mon 8/117:00 amEYW - CAE
1 stop5h 32mDelta
Deal found 4/30$274
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:26 amGSP - EYW
1 stop5h 44mAmerican Airlines
Sun 5/2511:28 amEYW - GSP
1 stop6h 20mAmerican Airlines
Deal found 4/30$275
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/79:51 pmMYR - EYW
1 stop18h 51mMultiple Airlines
Thu 6/128:53 amEYW - MYR
3 stops34h 29mMultiple Airlines
Deal found 4/30$297
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/79:51 pmMYR - EYW
1 stop18h 51mAllegiant Air
Thu 6/128:53 amEYW - MYR
2 stops33h 22mAllegiant Air
Deal found 4/30$302
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/12:53 pmCLT - EYW
1 stop18h 40mMultiple Airlines
Thu 6/58:53 amEYW - CLT
2 stops30h 44mMultiple Airlines
Deal found 4/30$312
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/79:43 amCHS - EYW
2 stops22h 20mMultiple Airlines
Thu 6/128:53 amEYW - CHS
2 stops32h 59mMultiple Airlines
Deal found 4/30$322

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

Fly from

South Carolina

Fly to

Key West

Route

Depart

Return

Price

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Thu 7/24

9:36 pm-9:22 am

1 stop11h 46m

Key West

Thu 7/31

1:47 pm-10:30 am

1 stop20h 43m

$199

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Fri 9/26

3:42 pm-7:44 pm

1 stop4h 02m

Key West

Mon 9/29

2:35 pm-9:21 pm

1 stop6h 46m

$249

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Thu 5/15

1:24 pm-8:07 pm

1 stop6h 43m

Key West

Mon 5/19

7:00 am-12:29 pm

1 stop5h 29m

$259

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Fri 5/30

5:00 am-12:10 pm

1 stop7h 10m

Key West

Tue 6/3

5:24 pm-10:31 pm

1 stop5h 07m

$274

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Mon 8/4

3:10 pm-7:49 pm

1 stop4h 39m

Key West

Mon 8/11

7:00 am-12:32 pm

1 stop5h 32m

$274

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Wed 5/21

6:26 am-12:10 pm

1 stop5h 44m

Key West

Sun 5/25

11:28 am-5:48 pm

1 stop6h 20m

$275

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Mon 6/16

2:50 pm-7:39 pm

1 stop4h 49m

Key West

Tue 6/24

7:10 am-2:00 pm

1 stop6h 50m

$277

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Sun 8/3

4:33 pm-9:22 am

1 stop16h 49m

Key West

Thu 8/7

1:47 pm-8:28 pm

1 stop6h 41m

$288

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 6/7

9:51 pm-4:42 pm

1 stop18h 51m

Key West

Thu 6/12

8:53 am-7:22 pm

3 stops34h 29m

$297

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 6/7

9:51 pm-4:42 pm

1 stop18h 51m

Key West

Thu 6/12

8:53 am-6:15 pm

2 stops33h 22m

$302

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 37 results
1
2
3
4

Best time to book a flight from South Carolina to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Key West

What is the cheapest month to book a flight from South Carolina to Key West?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to EYW?

Find hourly flight availability from South Carolina to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Key West as you normally would.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated May 1, 2025.
See what other customers who have flown with Breeze Airways, Delta and United Airlines from South Carolina to Key West have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
160 reviews

Overall

8.1

Comfort

8.2

Boarding

8.3

Food

6.7

Crew

8.8

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
160 reviews
Breeze Airways
8.1
Very good
160 reviews

Overall

8.1

Comfort

8.2

Boarding

8.3

Food

6.7

Crew

8.8

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,934 reviews
Breeze Airways
8.1
Very good
160 reviews

Overall

8.1

Comfort

8.2

Boarding

8.3

Food

6.7

Crew

8.8

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,696 reviews
Breeze Airways
8.1
Very good
160 reviews

Overall

8.1

Comfort

8.2

Boarding

8.3

Food

6.7

Crew

8.8

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Allegiant Air
7.3
Good
734 reviews
Breeze Airways
8.1
Very good
160 reviews

Overall

8.1

Comfort

8.2

Boarding

8.3

Food

6.7

Crew

8.8

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
American Airlines
7.2
Good
10,000 reviews
Breeze Airways
8.1
Very good
160 reviews

Overall

8.1

Comfort

8.2

Boarding

8.3

Food

6.7

Crew

8.8

Entertainment

6.6

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from South Carolina?

    For a flight from South Carolina to Key West, you will be flying into Key West. Key West (EYW) is just 2.6 mi from the center of the city.

  • What are the cheapest airlines to fly from South Carolina to Key West one-way?

    $114 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $129 and $169, respectively.

  • What are the most popular routes from South Carolina to Key West?

    When deciding which route to take from South Carolina to Key West consider Charlotte Douglas - Key West, Charleston - Key West or Greenville - Key West as they are the most popular.

  • Can I find deals for flights from South Carolina to Key West that include hotel bookings?

    Yes. In addition to deals on South Carolina to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Key West.

  • Can I find deals for business class flights from South Carolina to Key West?

    Yes. Cheapflights offers flight deals from South Carolina to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Key West?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Key West

See prices for flight routes from nearby airports that may be better suited for you.
LaGuardia to Fort Lauderdale flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to Miami flights
LaGuardia to Miami flights
Newark to Miami flights
Newark to Orlando flights
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
LaGuardia to Orlando flights
John F Kennedy Intl to West Palm Beach flights
Los Angeles to Miami flights
Newark to Tampa flights
Dallas/Fort Worth to Orlando flights
Los Angeles to Orlando flights
John F Kennedy Intl to Tampa flights
Dallas/Fort Worth to Miami flights
Dallas/Fort Worth to Fort Lauderdale flights
O'Hare Intl to Orlando flights
Boston to Miami flights
LaGuardia to Tampa flights
San Francisco to Miami flights
Philadelphia to Orlando flights
Baltimore to Miami flights
Boston to Orlando flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Miami flights
Reagan-National to Miami flights
Los Angeles to Fort Lauderdale flights
Atlanta to Miami flights
Baltimore to Fort Lauderdale flights
Dulles Intl to Miami flights
Philadelphia to Fort Lauderdale flights
Hobby to Miami flights
Boston to Fort Lauderdale flights
Philadelphia to Miami flights
Newark to West Palm Beach flights
Baltimore to Orlando flights
Hobby to Orlando flights
Boston to Tampa flights
Denver to Orlando flights
Atlanta to Fort Lauderdale flights
Dulles Intl to Orlando flights
LaGuardia to West Palm Beach flights
Detroit to Fort Lauderdale flights
Denver to Miami flights
O'Hare Intl to Tampa flights
Seattle to Orlando flights
Reagan-National to Orlando flights
Cleveland to Orlando flights
Providence to Orlando flights

Top 2 airlines flying from South Carolina to Key West

Discover the top 2 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$427FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$481FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.