Key West

$41+ Cheap flights from Knoxville to Key West (TYS - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
Apr 15 — Apr 221
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Key West with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key West are usually found in November or October, booked 19 days in advance, depart on a Tuesday or Monday and return on a Monday

Cheap flight deals from Knoxville to Key West

Cheapest flights from Knoxville to Key West
Explore the most affordable flight options available from Knoxville to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Fri 4/1711:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/11$96
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:30 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 7/1310:31 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/10$103
This Gotogate deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Fri 3/2711:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/14$105
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 3/3011:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/12$112
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:30 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 7/1310:31 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/10$116
This Booking.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Fri 4/1011:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/11$122
This Booking.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Fri 6/1210:31 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/11$134
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 4/1311:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/11$146
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:42 pm
TYS
-
EYW
1 stop24h 31m
Multiple Airlines
Mon 7/1310:31 am
EYW
-
TYS
Nonstop2h 15m
Multiple Airlines
Deal found 3/10$147
This Gotogate deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 4/1311:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/13$148

Find flight deals from Knoxville to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$96
(Kiwi.com)

One-way from

$41
(Kiwi.com)

Popular in

August

Cheapest in

November

Average price

$221

Good round-trip deal

$107 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Key West flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Key West flights.
From Knoxville McGhee Tyson to Key West
One-way flight from Knoxville McGhee Tyson to Key West
Highest demand for flights based on searches. 20% potential increase in price ($66 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in March 2026
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Key West.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Knoxville to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 4/10

8:00 am-10:11 am

Nonstop2h 11m

Key West

Mon 4/13

11:01 am-1:16 pm

Nonstop2h 15m

$148

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 4/13

1:15 pm-11:30 am

2 stops22h 15m

Key West

Fri 4/17

11:01 am-1:16 pm

Nonstop2h 15m

$246

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Wed 7/1

5:18 pm-12:48 pm

1 stop19h 30m

Key West

Mon 7/6

10:31 am-12:46 pm

Nonstop2h 15m

$248

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sun 3/29

9:56 pm-2:09 pm

1 stop16h 13m

Key West

Thu 4/2

10:32 pm-11:20 pm

1 stop24h 48m

$291

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sun 7/19

8:15 am-3:27 pm

1 stop7h 12m

Key West

Sat 7/25

2:44 pm-10:57 pm

1 stop8h 13m

$298

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sat 7/11

5:59 pm-12:48 pm

1 stop18h 49m

Key West

Sat 7/18

2:44 pm-10:57 pm

1 stop8h 13m

$306

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 3/26

6:00 am-9:43 pm

1 stop15h 43m

Key West

Tue 3/31

12:25 pm-10:36 am

1 stop22h 11m

$330

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sun 3/29

7:00 am-9:09 am

2 stops26h 09m

Key West

Thu 4/2

10:32 pm-11:20 pm

1 stop24h 48m

$346

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sat 7/4

4:00 pm-7:44 pm

1 stop3h 44m

Key West

Wed 7/8

6:00 pm-11:46 pm

1 stop5h 46m

$359

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 6/25

1:01 pm-10:27 am

2 stops21h 26m

Key West

Sun 7/5

7:56 pm-11:19 pm

1 stop27h 23m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Key West in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key West

How far ahead should I book a flight from Knoxville to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key West. Price data was last updated on March 13, 2026.

To ensure you get the cheapest price possible for a flight from Knoxville to Key West, you should look to book at least 19 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Key West?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Key West (average of $84). Flying from Knoxville to Key West in April is currently the most expensive (average of $91). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to EYW?

Find hourly flight availability from Knoxville to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 16, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Key West as you normally would.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated March 16, 2026.
See what other customers who have flown with Delta,Allegiant Air, andAmerican Airlines from Knoxville to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Knoxville to Key West flight route?

  • How long is the flight from Knoxville to Key West?

    Allegiant Air can get you from Knoxville to Key West in just under 2h 11m. Your travel time will be generally consistent. The distance between Knoxville and Key West is about 788 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from Knoxville to Key West round-trip?

    According to our current data, Allegiant Air ($84), American Airlines ($250), and Delta ($268) offers the cheapest pricing from Knoxville to Key West. Allegiant Air is currently priced 67% below the average price you’ll pay for this route.

  • What are the cheapest flights from Knoxville to Key West?

    Looking for the cheapest flight from Knoxville to Key West? While on average our users pay $148, our data indicates the cheapest price to be $88. The most popular route (Knoxville McGhee Tyson - Key West), is priced around $148.

  • Can I find deals for flights from Knoxville to Key West that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key West.

  • Can I find deals for business class flights from Knoxville to Key West?

    Yes. Cheapflights offers flight deals from Knoxville to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key West?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Key West (average of $84). Flying from Knoxville to Key West in April is currently the most expensive (average of $91). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Key West

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Knoxville to Key West

Discover the top 3 airlines that operate flights from Knoxville to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$84Average$159FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$250Average$410FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$408FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.