HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key West

$200+ Cheap flights from Knoxville to Key West (TYS - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Key West with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key West are usually found in July or June, booked 48 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Knoxville to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$206
(Mytrip)

One-way from

$200
(Mytrip)

Popular in

September

Cheapest in

July

Average price

$318

Good round-trip deal

$118 or less
From Knoxville McGhee Tyson to Key West
Search Deals
One-way flight from Knoxville McGhee Tyson to Key West
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Key West.
Search Deals

Find flight deals from Knoxville to Key West

Cheapest flights from Knoxville to Key West
Explore the most affordable flight options available from Knoxville to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/1412:06 pmTYS - EYW
Nonstop2h 11mAllegiant Air
dom. 11/169:36 pmEYW - TYS
1 stop23h 01mAllegiant Air
Deal found 6/11$206
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/112:36 pmTYS - EYW
1 stop5h 13mDelta
lun. 7/147:00 amEYW - TYS
1 stop6h 51mDelta
Deal found 6/9$249
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/97:10 amTYS - EYW
2 stops28h 31mMultiple Airlines
mié. 7/163:55 pmEYW - TYS
1 stop5h 03mMultiple Airlines
Deal found 6/10$252
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/86:00 amTYS - EYW
1 stop4h 53mAmerican Airlines
sáb. 9/1311:25 amEYW - TYS
2 stops11h 38mAmerican Airlines
Deal found 6/12$271
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/109:55 amTYS - EYW
2 stops28h 05mUnited Airlines
lun. 7/146:45 pmEYW - TYS
2 stops20h 13mUnited Airlines
Deal found 6/11$386

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Knoxville to Key West that are best for you.

Fly from

Knoxville

Fly to

Key West

Route

Depart

Return

Price

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

mié. 7/9

9:48 pm-8:04 am

1 stop10h 16m

Key West

mié. 7/16

3:55 pm-8:58 pm

1 stop5h 03m

$210

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

vie. 7/11

2:36 pm-7:49 pm

1 stop5h 13m

Key West

lun. 7/14

7:00 am-1:51 pm

1 stop6h 51m

$249

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

mié. 7/9

7:10 am-11:41 am

2 stops28h 31m

Key West

mié. 7/16

3:55 pm-8:58 pm

1 stop5h 03m

$252

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

lun. 9/8

6:00 am-10:53 am

1 stop4h 53m

Key West

sáb. 9/13

11:25 am-11:03 pm

2 stops11h 38m

$271

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

jue. 7/10

9:55 am-2:00 pm

2 stops28h 05m

Key West

lun. 7/14

6:45 pm-2:58 pm

2 stops20h 13m

$386

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

dom. 6/15

7:30 am-9:33 am

1 stop26h 03m

$200

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

dom. 6/15

6:00 am-1:17 pm

3 stops31h 17m

$517

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Knoxville to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key West

How far ahead should I book a flight from Knoxville to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key West. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville to Key West, you should look to book at least 48 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Key West?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Key West (average of $328). Flying from Knoxville to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to EYW?

Find hourly flight availability from Knoxville to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Key West in the morning. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight at noon.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated junio 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Knoxville to Key West. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Allegiant Air
7.3
Good
725 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Key West round-trip?

    According to our current data, Allegiant Air ($206), Delta ($249), and American Airlines ($271) offers the cheapest pricing from Knoxville to Key West. Allegiant Air is currently priced 48% below the average price you’ll pay for this route.

  • What are the cheapest flights from Knoxville to Key West?

    Looking for the cheapest flight from Knoxville to Key West? While on average our users pay $136, our data indicates the cheapest price to be $115. The most popular route (Knoxville McGhee Tyson - Key West), is priced around $206.

  • Can I find deals for flights from Knoxville to Key West that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key West.

  • Can I find deals for business class flights from Knoxville to Key West?

    Yes. Cheapflights offers flight deals from Knoxville to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key West?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Key West (average of $328). Flying from Knoxville to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Key West

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Orlando flights
Nashville to Fort Lauderdale flights
Memphis to Orlando flights
Memphis to Miami flights
Nashville to Miami flights
Nashville to Tampa flights
Memphis to Fort Lauderdale flights
Nashville to St Petersburg flights
Nashville to Panama City flights
Nashville to Sarasota flights
Knoxville to Miami flights
Knoxville to Fort Lauderdale flights
Nashville to West Palm Beach flights
Nashville to Fort Myers flights
Chattanooga to Orlando flights
Knoxville to Orlando Sanford Intl flights
Nashville to Pensacola flights
Chattanooga to Miami flights
Nashville to Key West flights
Memphis to Pensacola flights
Chattanooga to Tampa flights
Knoxville to Orlando flights
Memphis to Tampa flights
Knoxville to Tampa flights
Chattanooga to Fort Lauderdale flights
Chattanooga to Orlando Sanford Intl flights
Nashville to Jacksonville flights
Chattanooga to Sarasota flights
Memphis to Jacksonville flights
Memphis to Key West flights
Nashville to Valparaiso flights
Memphis to Panama City flights
Knoxville to Jacksonville flights
Knoxville to Panama City flights
Knoxville to St Petersburg flights
Memphis to Orlando Sanford Intl flights
Memphis to Sarasota flights
Chattanooga to Panama City flights
Chattanooga to Fort Myers flights
Chattanooga to Daytona Beach flights
Knoxville to Sarasota flights
Knoxville to Pensacola flights
Knoxville to West Palm Beach flights
Memphis to West Palm Beach flights
Memphis to Valparaiso flights
Memphis to Fort Myers flights
Nashville to Daytona Beach flights
Chattanooga to Jacksonville flights
Memphis to St Petersburg flights

Top 3 airlines flying from Knoxville to Key West

Discover the top 3 airlines that operate flights from Knoxville to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$78Average$207FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$248Average$423FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$480FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.