$169+ Cheap flights from Iowa to Key West (EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Nov 14 — Nov 211
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Key West
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Cheapest flights from Iowa to Key WestExplore the most affordable flight options available from Iowa to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 15, 2026.
Explore the most affordable flight options available from Iowa to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 15, 2026.
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:05 am -
1 stop4h 43m
Tue 12/156:06 pm -
1 stop6h 04m
Deal found 10/12![Delta logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:59 pm -
1 stop21h 21m
Wed 12/94:40 pm -
2 stops25h 06m
Deal found 10/12![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:03 pm -
1 stop20h 05m
Wed 11/184:51 pm -
1 stop25h 09m
Deal found 10/13![Allegiant Air logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:42 am -
1 stop24h 56m
Sun 11/18:36 pm -
1 stop22h 06m
Deal found 10/13![Allegiant Air logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:59 am -
1 stop23h 03m
Thu 11/58:54 am -
1 stop24h 00m
Deal found 10/14![Allegiant Air logo]()
$366
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:45 am -
1 stop6h 07m
Wed 12/96:32 pm -
1 stop7h 01m
Deal found 10/10![American Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:48 pm -
1 stop18h 19m
Sun 12/206:20 pm -
1 stop15h 09m
Deal found 10/12![Allegiant Air logo]()
$392
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
2 stops10h 19m
Tue 12/156:42 pm -
1 stop6h 17m
Deal found 10/11![American Airlines logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:53 am -
1 stop22h 25m
Sun 11/2212:08 pm -
2 stops30h 08m
Deal found 10/12![Multiple Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:00 am -
1 stop8h 44m
Sat 12/121:04 pm -
1 stop7h 25m
Deal found 10/12![American Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:00 am -
2 stops10h 27m
Tue 11/176:35 pm -
1 stop6h 04m
Deal found 10/15![American Airlines logo]()
$406
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:27 am -
1 stop7h 34m
Thu 11/56:11 pm -
1 stop5h 22m
Deal found 10/13![Delta logo]()
$408
Best flights from Iowa to Key WestDiscover carefully curated flight deals from Iowa to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 15, 2026.
Discover carefully curated flight deals from Iowa to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 15, 2026.
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:05 am -
1 stop4h 43m
Tue 12/156:06 pm -
1 stop6h 04m
Deal found 10/11![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:09 am -
2 stops11h 45m
Wed 2/35:56 pm -
1 stop7h 03m
Deal found 10/11![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:00 am -
1 stop9h 22m
Sat 1/95:54 pm -
1 stop6h 36m
Deal found 10/12![United Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:46 pm -
1 stop23h 10m
Mon 11/99:20 am -
1 stop14h 11m
Deal found 10/13![Allegiant Air logo]()
$519
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/301:00 pm -
1 stop5h 43m
Wed 2/36:00 pm -
1 stop5h 29m
Deal found 10/12![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:07 am -
2 stops9h 02m
Wed 1/205:58 pm -
1 stop7h 12m
Deal found 10/14![American Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:00 am -
1 stop9h 22m
Tue 1/124:09 pm -
1 stop7h 41m
Deal found 10/14![United Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:00 am -
2 stops8h 01m
Wed 11/44:00 pm -
1 stop6h 56m
Deal found 10/12![Delta logo]()
$474
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop8h 29m
Tue 11/34:10 pm -
1 stop7h 46m
Deal found 10/14![United Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/210:10 am -
1 stop6h 18m
Mon 2/86:48 pm -
1 stop18h 39m
Deal found 10/10![American Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/79:25 am -
1 stop6h 48m
Mon 1/115:54 pm -
1 stop6h 20m
Deal found 10/13![United Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/275:07 am -
2 stops13h 13m
Sat 2/68:06 pm -
2 stops14h 33m
Deal found 10/13![American Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:27 am -
1 stop7h 34m
Sat 11/76:11 pm -
1 stop5h 22m
Deal found 10/10![Delta logo]()
$619
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:00 am -
1 stop9h 23m
Sat 12/264:52 pm -
1 stop6h 37m
Deal found 10/12![United Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/86:00 am -
2 stops9h 30m
Wed 4/142:01 pm -
2 stops9h 16m
Deal found 10/11![American Airlines logo]()
$635
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/285:45 am -
1 stop6h 23m
Tue 2/22:35 pm -
1 stop8h 16m
Deal found 10/14![Delta logo]()
$647
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
2 stops10h 26m
Mon 1/251:52 pm -
2 stops10h 41m
Deal found 10/11![American Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:00 am -
1 stop6h 16m
Wed 2/34:09 pm -
1 stop6h 22m
Deal found 10/12![United Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
1 stop6h 29m
Fri 11/64:10 pm -
1 stop6h 45m
Deal found 10/11![United Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
1 stop6h 29m
Wed 11/184:10 pm -
1 stop6h 45m
Deal found 10/14![United Airlines logo]()
$723
Last-minute flights from Iowa to Key WestDiscover last-minute flight deals from Iowa to Key West. Data last updated October 15, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Key West. Data last updated October 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
2 stops28h 21m
Thu 10/228:36 pm -
1 stop12h 49m
Deal found 10/12![Multiple Airlines logo]()
$416
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:27 am -
1 stop7h 34m
Sat 10/246:11 pm -
1 stop5h 22m
Deal found 10/12![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:00 am -
2 stops10h 58m
Wed 10/281:43 pm -
2 stops11h 37m
Deal found 10/14![American Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:42 am -
1 stop24h 56m
Sun 11/18:36 pm -
1 stop22h 06m
Deal found 10/13![Allegiant Air logo]()
$366
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:07 am -
2 stops10h 04m
Sun 11/17:18 pm -
1 stop5h 40m
Deal found 10/13![American Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:59 am -
1 stop23h 03m
Thu 11/58:54 am -
1 stop24h 00m
Deal found 10/14![Allegiant Air logo]()
$366
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:08 am -
1 stop8h 03m
Wed 11/45:50 pm -
1 stop6h 36m
Deal found 10/10![American Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:27 am -
1 stop7h 34m
Thu 11/56:11 pm -
1 stop5h 22m
Deal found 10/13![Delta logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:03 pm -
1 stop20h 05m
Wed 11/184:51 pm -
1 stop25h 09m
Deal found 10/13![Allegiant Air logo]()
$364
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:00 am -
2 stops10h 27m
Tue 11/176:35 pm -
1 stop6h 04m
Deal found 10/15![American Airlines logo]()
$406
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:53 am -
1 stop22h 25m
Sun 11/2212:08 pm -
2 stops30h 08m
Deal found 10/12![Multiple Airlines logo]()
$400
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:53 am -
1 stop22h 25m
Sun 11/2212:08 pm -
2 stops30h 08m
Deal found 10/13![Allegiant Air logo]()
$415
One-way flights from Iowa to Key WestSearch for one-way flight options from Iowa to Key West. Find affordable one-way fares based on user searches. Data last updated October 15, 2026.
Search for one-way flight options from Iowa to Key West. Find affordable one-way fares based on user searches. Data last updated October 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:06 pm -
2 stops14h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:28 am -
1 stop21h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Allegiant Air logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:30 am -
3 stops27h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:51 pm -
1 stop19h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Allegiant Air logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:43 am -
2 stops47h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:58 pm -
3 stops42h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$298
This WAYA deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/61:04 pm -
1 stop20h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Allegiant Air logo]()
$307
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:03 am -
1 stop6h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:37 pm -
2 stops14h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![American Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
2 stops10h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:23 am -
1 stop8h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![American Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:22 am -
1 stop6h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![American Airlines logo]()
$486
Find flight deals from Iowa to Key West
Keep the following information in mind while searching for Iowa to Key West flight deals. Data was last updated October 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Delta) |
One-way from | $169 (Kiwi.com) |
Popular in | May |
Cheapest in | July |
Average price | $546 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 15, 2026.
Use the filters below to find and compare flights from Iowa to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Cedar RapidsKey West
CID Cedar Rapids - EYW Key West
CIDEYW
Cedar Rapids
Mon 11/23
6:06 pm-9:24 am
2 stops14h 18m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$169
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Thu 10/22
8:43 am-9:02 am
2 stops47h 19m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$261
Cedar RapidsKey West
CID Cedar Rapids - EYW Key West
CIDEYW
Cedar Rapids
Mon 11/23
6:06 pm-10:17 am
3 stops39h 11m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$287
Cedar RapidsKey West
CID Cedar Rapids - EYW Key West
CIDEYW
Cedar Rapids
Tue 12/8
5:05 am-10:48 am
1 stop4h 43m
Key West
Tue 12/15
6:06 pm-11:10 pm
1 stop6h 04m
$311
Quickest round-trip
Cedar RapidsKey West
CID Cedar Rapids - EYW Key West
CIDEYW
Cedar Rapids
Tue 11/24
8:03 am-3:29 pm
1 stop6h 26m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$349
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Mon 11/2
2:56 pm-10:42 am
2 stops42h 46m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$360
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Sat 1/30
1:00 pm-7:43 pm
1 stop5h 43m
Key West
Wed 2/3
6:00 pm-10:29 pm
1 stop5h 29m
$379
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Sat 2/6
7:37 pm-11:02 am
2 stops14h 25m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$382
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Sat 1/30
5:09 am-5:54 pm
2 stops11h 45m
Key West
Wed 2/3
5:56 pm-11:59 pm
1 stop7h 03m
$407
Cedar RapidsKey West
CID Cedar Rapids - EYW Key West
CIDEYW
Cedar Rapids
Wed 1/13
5:07 am-3:09 pm
2 stops9h 02m
Key West
Wed 1/20
5:58 pm-12:10 am
1 stop7h 12m
$417
Showing 1-10 of 30 resultsSorted by cheapest first
Best time to book a flight from Iowa to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Iowa with our price prediction graph.
CID-EYW
DSM-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Key West
USIA-EYW
CID-EYW
DSM-EYW
What is the cheapest month to book a flight from Iowa to Key West?
Currently, July is the cheapest month in which you can book a flight from Iowa to Key West (average of $416). Flying from Iowa to Key West in October is currently the most expensive (average of $546). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Key West?
Airfare is below average for this route at the moment.
Iowa to Key West flights typically cost between $456 and $655 in April.The cheapest round-trip price found within the last 5 days was $319 on American Airlines (Apr 7-Apr 14).
Related info for your journey
Find useful and relevant information for your journey from Iowa to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Key West
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Complete your trip
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Search flights from Iowa to Key West by cabin class
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 15, 2026.
Iowa and Key West flights
Browse other Iowa and Key West flight options. Last updated on October 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Key West flights
Consider these flights traveling from Iowa to Key West.
Top 3 airlines flying from Iowa to Key West
Discover the top 3 airlines that operate flights from Iowa to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$431 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$305 | Average$481 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$546 | FlexibilityNo cancel fee | On-timeN/A |