$173+ Cheap flights from Iowa to Key West (EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Sep 22 — Sep 291
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Key West
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Cheapest flights from Iowa to Key WestExplore the most affordable flight options available from Iowa to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
Explore the most affordable flight options available from Iowa to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops27h 19m
Thu 10/2912:01 pm -
1 stop21h 08m
Deal found 8/19![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
2 stops47h 41m
Thu 11/58:54 pm -
1 stop12h 27m
Deal found 8/19![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:59 am -
1 stop23h 25m
Thu 10/2912:01 pm -
1 stop21h 08m
Deal found 8/19![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:59 am -
1 stop23h 03m
Thu 10/298:37 am -
1 stop24h 32m
Deal found 8/22![Allegiant Air logo]()
$291
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:00 am -
2 stops8h 02m
Tue 11/176:02 pm -
1 stop5h 43m
Deal found 8/21![Delta logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
2 stops33h 51m
Thu 10/228:36 pm -
1 stop12h 49m
Deal found 8/21![Allegiant Air logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:51 pm -
1 stop14h 21m
Fri 10/232:03 pm -
1 stop21h 36m
Deal found 8/23![Allegiant Air logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:47 pm -
1 stop17h 32m
Fri 10/308:29 am -
1 stop10h 55m
Deal found 8/20![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:04 pm -
1 stop20h 04m
Thu 12/107:22 pm -
1 stop23h 17m
Deal found 8/18![Allegiant Air logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:47 pm -
1 stop17h 32m
Thu 10/298:37 am -
1 stop8h 19m
Deal found 8/19![Multiple Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:40 am -
1 stop5h 46m
Wed 9/96:19 pm -
1 stop5h 07m
Deal found 8/19![Delta logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:03 pm -
1 stop20h 05m
Thu 11/1910:48 am -
2 stops31h 28m
Deal found 8/18![Allegiant Air logo]()
$321
Best flights from Iowa to Key WestDiscover carefully curated flight deals from Iowa to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
Discover carefully curated flight deals from Iowa to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:00 am -
2 stops8h 02m
Tue 11/176:02 pm -
1 stop5h 43m
Deal found 8/21![Delta logo]()
$296
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:15 am -
2 stops9h 07m
Wed 1/134:05 pm -
1 stop7h 56m
Deal found 8/20![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:45 am -
1 stop8h 09m
Wed 10/282:34 pm -
1 stop6h 51m
Deal found 8/19![American Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:40 am -
1 stop5h 46m
Wed 9/96:19 pm -
1 stop5h 07m
Deal found 8/19![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:45 pm -
1 stop5h 16m
Tue 10/136:10 pm -
1 stop5h 56m
Deal found 8/21![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop8h 11m
Sat 10/247:19 pm -
1 stop5h 39m
Deal found 8/18![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop7h 18m
Tue 10/274:10 pm -
1 stop6h 45m
Deal found 8/22![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:46 pm -
1 stop5h 14m
Tue 9/157:40 am -
1 stop5h 59m
Deal found 8/22![Delta logo]()
$345
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:00 am -
2 stops13h 17m
Wed 10/74:45 pm -
1 stop8h 13m
Deal found 8/18![American Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:08 pm -
1 stop6h 49m
Thu 9/106:19 pm -
1 stop5h 07m
Deal found 8/20![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:46 pm -
1 stop5h 14m
Fri 9/256:19 pm -
1 stop6h 40m
Deal found 8/21![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
2 stops9h 58m
Tue 10/272:15 pm -
1 stop5h 53m
Deal found 8/22![American Airlines logo]()
$461
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:10 pm -
1 stop6h 47m
Wed 9/96:19 pm -
1 stop5h 59m
Deal found 8/21![Delta logo]()
$382
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:30 am -
2 stops11h 57m
Tue 11/171:52 pm -
2 stops11h 07m
Deal found 8/22![American Airlines logo]()
$463
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:32 am -
1 stop6h 46m
Wed 10/282:51 pm -
2 stops24h 04m
Deal found 8/18![United Airlines logo]()
$613
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:02 am -
2 stops9h 09m
Thu 9/102:15 pm -
2 stops11h 05m
Deal found 8/22![American Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:31 am -
1 stop7h 29m
Tue 9/156:19 pm -
1 stop5h 07m
Deal found 8/20![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:00 am -
1 stop6h 33m
Tue 1/194:00 pm -
1 stop8h 59m
Deal found 8/21![American Airlines logo]()
$486
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:15 am -
1 stop4h 33m
Mon 11/236:05 pm -
1 stop6h 04m
Deal found 8/23![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:13 am -
1 stop6h 16m
Mon 11/234:10 pm -
1 stop6h 12m
Deal found 8/23![United Airlines logo]()
$662
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:27 am -
1 stop7h 34m
Wed 10/286:10 pm -
1 stop5h 23m
Deal found 8/22![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:45 am -
2 stops8h 37m
Thu 1/284:05 pm -
1 stop7h 59m
Deal found 8/19![United Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:57 am -
2 stops9h 58m
Sat 11/144:45 pm -
1 stop8h 33m
Deal found 8/23![American Airlines logo]()
$508
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:15 am -
1 stop4h 33m
Wed 11/252:06 pm -
2 stops10h 00m
Deal found 8/23![Delta logo]()
$414
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/213:48 pm -
1 stop22h 37m
Mon 1/254:00 pm -
1 stop24h 18m
Deal found 8/20![American Airlines logo]()
$511
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:00 am -
2 stops8h 00m
Wed 11/252:06 pm -
2 stops10h 00m
Deal found 8/23![Delta logo]()
$420
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:01 am -
2 stops12h 26m
Wed 12/21:52 pm -
2 stops11h 26m
Deal found 8/21![American Airlines logo]()
$566
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:20 pm -
1 stop6h 40m
Tue 10/136:10 pm -
1 stop5h 56m
Deal found 8/21![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:20 pm -
1 stop6h 40m
Wed 10/146:10 pm -
1 stop6h 49m
Deal found 8/20![Delta logo]()
$426
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:00 am -
1 stop10h 46m
Sat 1/94:00 pm -
1 stop19h 51m
Deal found 8/22![American Airlines logo]()
$584
Last-minute flights from Iowa to Key WestDiscover last-minute flight deals from Iowa to Key West. Data last updated August 23, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Key West. Data last updated August 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:18 pm -
1 stop17h 13m
Sun 9/66:11 pm -
1 stop17h 09m
Deal found 8/23![Multiple Airlines logo]()
$365
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:28 am -
1 stop7h 29m
Wed 9/96:19 pm -
1 stop5h 07m
Deal found 8/21![Delta logo]()
$348
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:28 am -
1 stop7h 29m
Thu 9/106:19 pm -
1 stop5h 07m
Deal found 8/20![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:10 pm -
1 stop6h 47m
Wed 9/96:19 pm -
1 stop5h 59m
Deal found 8/21![Delta logo]()
$382
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:40 am -
1 stop5h 46m
Wed 9/96:19 pm -
1 stop5h 07m
Deal found 8/19![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:40 am -
1 stop5h 46m
Thu 9/106:19 pm -
1 stop5h 07m
Deal found 8/21![Delta logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm -
2 stops20h 29m
Thu 9/106:11 pm -
1 stop15h 58m
Deal found 8/20![Multiple Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:53 am -
1 stop7h 18m
Wed 9/91:47 pm -
2 stops11h 17m
Deal found 8/19![American Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:46 pm -
1 stop5h 14m
Tue 9/157:40 am -
1 stop5h 59m
Deal found 8/21![Delta logo]()
$345
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:31 am -
1 stop7h 29m
Tue 9/156:19 pm -
1 stop5h 07m
Deal found 8/20![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:03 am -
1 stop5h 46m
Tue 9/2211:30 am -
2 stops11h 07m
Deal found 8/19![American Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
2 stops35h 54m
Fri 9/258:58 am -
1 stop8h 07m
Deal found 8/20![Multiple Airlines logo]()
$386
One-way flights from Iowa to Key WestSearch for one-way flight options from Iowa to Key West. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
Search for one-way flight options from Iowa to Key West. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:29 am -
1 stop19h 18m
Deal found 8/19![Allegiant Air logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:29 pm -
2 stops38h 52m
Deal found 8/21![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:35 pm -
1 stop23h 59m
Deal found 8/21![Allegiant Air logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:21 pm -
1 stop21h 50m
Deal found 8/19![Allegiant Air logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:34 pm -
3 stops42h 32m
Deal found 8/20![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sat 9/267:29 pm -
2 stops39h 50m
Deal found 8/21![Multiple Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:30 am -
1 stop6h 23m
Deal found 8/21![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:22 am -
1 stop6h 27m
Deal found 8/21![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:00 am -
1 stop5h 18m
Deal found 8/21![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:00 am -
2 stops8h 01m
Deal found 8/21![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:40 am -
1 stop5h 43m
Deal found 8/21![Delta logo]()
$347
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:30 am -
1 stop6h 23m
Deal found 8/21![Delta logo]()
$360
Find flight deals from Iowa to Key West
Keep the following information in mind while searching for Iowa to Key West flight deals. Data was last updated August 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $265 (Kiwi.com) |
One-way from | $173 (Kiwi.com) |
Popular in | February |
Cheapest in | September |
Average price | $477 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
Use the filters below to find and compare flights from Iowa to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Cedar RapidsKey West
CID Cedar Rapids - EYW Key West
CIDEYW
Cedar Rapids
Sat 11/14
11:00 am-8:02 pm
2 stops8h 02m
Key West
Tue 11/17
6:02 pm-10:45 pm
1 stop5h 43m
$296
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Sun 9/6
5:40 am-12:26 pm
1 stop5h 46m
Key West
Wed 9/9
6:19 pm-10:26 pm
1 stop5h 07m
$319
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Wed 1/6
6:15 am-4:22 pm
2 stops9h 07m
Key West
Wed 1/13
4:05 pm-11:01 pm
1 stop7h 56m
$324
OmahaKey West
OMA Omaha Eppley Airfield - EYW Key West
OMAEYW
Omaha Eppley Airfield
Tue 10/6
1:45 pm-8:01 pm
1 stop5h 16m
Key West
Tue 10/13
6:10 pm-11:06 pm
1 stop5h 56m
$333
OmahaKey West
OMA Omaha Eppley Airfield - EYW Key West
OMAEYW
Omaha Eppley Airfield
Fri 10/23
7:45 am-4:54 pm
1 stop8h 09m
Key West
Wed 10/28
2:34 pm-8:25 pm
1 stop6h 51m
$345
OmahaKey West
OMA Omaha Eppley Airfield - EYW Key West
OMAEYW
Omaha Eppley Airfield
Thu 9/10
1:46 pm-8:00 pm
1 stop5h 14m
Key West
Tue 9/15
7:40 am-12:39 pm
1 stop5h 59m
$345
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Sun 9/6
12:08 pm-7:57 pm
1 stop6h 49m
Key West
Thu 9/10
6:19 pm-10:26 pm
1 stop5h 07m
$349
OmahaKey West
OMA Omaha Eppley Airfield - EYW Key West
OMAEYW
Omaha Eppley Airfield
Fri 9/18
1:46 pm-8:00 pm
1 stop5h 14m
Key West
Fri 9/25
6:19 pm-11:59 pm
1 stop6h 40m
$357
OmahaKey West
OMA Omaha Eppley Airfield - EYW Key West
OMAEYW
Omaha Eppley Airfield
Sat 9/5
12:10 pm-7:57 pm
1 stop6h 47m
Key West
Wed 9/9
6:19 pm-11:18 pm
1 stop5h 59m
$382
Des MoinesKey West
DSM Des Moines - EYW Key West
DSMEYW
Des Moines
Sat 9/12
11:31 am-8:00 pm
1 stop7h 29m
Key West
Tue 9/15
6:19 pm-10:26 pm
1 stop5h 07m
$399
Showing 1-10 of 52 resultsSorted by cheapest first
Best time to book a flight from Iowa to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Iowa with our price prediction graph.
MLI-EYW
OMA-EYW
CID-EYW
DSM-EYW
LSE-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Key West
USIA-EYW
MLI-EYW
OMA-EYW
CID-EYW
DSM-EYW
What is the cheapest month to book a flight from Iowa to Key West?
Currently, September is the cheapest month in which you can book a flight from Iowa to Key West (average of $295). Flying from Iowa to Key West in October is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Key West?
Airfare is below average for this route at the moment.
Iowa to Key West flights typically cost between $352 and $557 in October.The cheapest round-trip price found within the last 5 days was $265 on Multiple Airlines (Oct 25-Oct 29).
Related info for your journey
Find useful and relevant information for your journey from Iowa to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Iowa to Key West
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Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Key West by cabin class
Find flights from Iowa to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 23, 2026.
Iowa and Key West flights
Browse other Iowa and Key West flight options. Last updated on August 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Key West flights
Consider these flights traveling from Iowa to Key West.
Top 3 airlines flying from Iowa to Key West
Discover the top 3 airlines that operate flights from Iowa to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$411 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$546 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$479 | FlexibilityNo cancel fee | On-time71% |