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Key West

$128+ Cheap flights from Iowa to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Jun 16 — Jun 231
Tue 6/16
Tue 6/23
1 adult, Economy
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Cheap flight deals from Iowa to Key West

Cheapest flights from Iowa to Key West
Explore the most affordable flight options available from Iowa to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:12 am
CID
-
EYW
1 stop26h 04m
Allegiant Air
Sat 6/62:48 pm
EYW
-
CID
1 stop18h 39m
Allegiant Air
Deal found 5/13$273
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:12 am
CID
-
EYW
1 stop26h 04m
Allegiant Air
Fri 6/54:35 pm
EYW
-
CID
1 stop20h 12m
Allegiant Air
Deal found 5/13$275
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:04 am
DSM
-
EYW
1 stop7h 39m
Delta
Wed 12/96:00 pm
EYW
-
DSM
1 stop5h 29m
Delta
Deal found 5/12$289
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:37 pm
DSM
-
EYW
1 stop23h 21m
Allegiant Air
Mon 6/12:51 pm
EYW
-
DSM
1 stop25h 44m
Allegiant Air
Deal found 5/14$297
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:12 am
CID
-
EYW
1 stop26h 04m
Allegiant Air
Thu 6/49:16 pm
EYW
-
CID
1 stop11h 56m
Allegiant Air
Deal found 5/13$299
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/204:22 pm
DSM
-
EYW
1 stop21h 50m
Allegiant Air
Sat 6/272:48 pm
EYW
-
DSM
1 stop9h 04m
Allegiant Air
Deal found 5/12$305
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:48 am
DSM
-
EYW
1 stop26h 39m
Allegiant Air
Mon 8/103:27 pm
EYW
-
DSM
1 stop21h 36m
Allegiant Air
Deal found 5/12$307
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:08 pm
DSM
-
EYW
1 stop6h 37m
American Airlines
Wed 12/98:00 am
EYW
-
DSM
1 stop8h 37m
American Airlines
Deal found 5/13$309
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:12 am
CID
-
EYW
1 stop26h 04m
Allegiant Air
Sun 6/79:16 pm
EYW
-
CID
1 stop11h 56m
Allegiant Air
Deal found 5/13$310
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:38 am
OMA
-
EYW
1 stop26h 20m
Allegiant Air
Mon 6/12:51 pm
EYW
-
OMA
1 stop21h 26m
Allegiant Air
Deal found 5/15$312
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:16 pm
DSM
-
EYW
1 stop6h 31m
American Airlines
Sat 11/74:26 pm
EYW
-
DSM
1 stop7h 50m
American Airlines
Deal found 5/13$314
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/811:13 am
DSM
-
EYW
1 stop25h 18m
Multiple Airlines
Wed 8/1211:46 am
EYW
-
DSM
2 stops34h 45m
Multiple Airlines
Deal found 5/14$315

Find flight deals from Iowa to Key West

Keep the following information in mind while searching for Iowa to Key West flight deals. Data was last updated May 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$273
(Kiwi.com)

One-way from

$128
(Kiwi.com)

Popular in

February

Cheapest in

July

Average price

$378
Provider with most accurate pricing for Des Moines-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Key West flights.
Search Deals
From Iowa to Key West
Search Deals
One-way flight from Iowa to Key West
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Iowa to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Wed 6/10

11:28 am-5:27 pm

1 stop4h 59m

Key West

Tue 6/16

7:50 am-1:35 pm

1 stop6h 45m

$309

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Fri 5/29

10:38 am-1:58 pm

1 stop26h 20m

Key West

Mon 6/1

2:51 pm-11:17 am

1 stop21h 26m

$312

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Fri 5/29

1:37 pm-1:58 pm

1 stop23h 21m

Key West

Mon 6/1

2:51 pm-3:35 pm

1 stop25h 44m

$313

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Sat 10/24

3:32 pm-10:11 pm

1 stop5h 39m

Key West

Sat 10/31

4:05 pm-9:14 pm

1 stop6h 09m

$337

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Fri 5/29

6:02 am-6:49 pm

2 stops11h 47m

Key West

Mon 6/1

7:29 pm-12:17 am

1 stop5h 48m

$349

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Sat 5/30

6:57 am-5:23 pm

2 stops9h 26m

Key West

Wed 6/3

2:03 pm-9:14 pm

1 stop8h 11m

$380

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Sat 7/4

7:20 am-7:23 pm

2 stops11h 03m

Key West

Wed 7/8

4:41 pm-10:00 pm

1 stop6h 19m

$384

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Sat 5/30

5:05 am-6:49 pm

2 stops12h 44m

Key West

Wed 6/3

1:39 pm-10:03 pm

2 stops9h 24m

$386

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Fri 6/12

7:10 am-7:10 pm

2 stops11h 00m

Key West

Mon 6/15

7:29 pm-12:12 am

1 stop5h 43m

$399

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Sun 7/5

9:48 am-2:37 pm

1 stop27h 49m

Key West

Thu 7/9

7:53 pm-9:35 am

1 stop14h 42m

$405

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Showing 1-10 of 47 resultsSorted by cheapest first
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Best time to book a flight from Iowa to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Key West

How far ahead should I book a flight from Iowa to Key West?

The price you pay for your flight from Iowa to Key West may vary depending on when you book. For the best chance of a lower fare, look to book 35 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Iowa to Key West?

Currently, July is the cheapest month in which you can book a flight from Iowa to Key West (average of $76). Flying from Iowa to Key West in December is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Iowa to Key West?

Related info for your journey

Find useful and relevant information for your journey from Iowa to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from Iowa?

    Located just 2.6 mi from the city center, Key West (EYW) is the airport most travelers will use when flying to Key West from Iowa.

  • How long is the flight from Iowa to Key West?

    Airlines like Delta, Allegiant Air, and United Airlines fly from Iowa to Key West in about 4h 59m. The time it takes to get you to your destination can typically vary by up to 21h 21m. The distance between Iowa and Key West is about 1357 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Key West?

    While some choose either Omaha Eppley Airfield - Key West or Cedar Rapids - Key West, Des Moines - Key West is the most popular route from Iowa to Key West.

  • Can I find deals for flights from Iowa to Key West that include hotel bookings?

    Yes. In addition to deals on Iowa to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Key West.

  • Can I find deals for business class flights from Iowa to Key West?

    Yes. Cheapflights offers flight deals from Iowa to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Key West?

    Currently, July is the cheapest month in which you can book a flight from Iowa to Key West (average of $76). Flying from Iowa to Key West in December is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Key West

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Key West

Discover the top 4 airlines that operate flights from Iowa to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$174FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$230Average$408FlexibilityNo cancel feeOn-time69%
DeltaCheapest$243Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$259Average$474FlexibilityNo cancel feeOn-time71%

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