How popular is this St. Louis to Key Largo flight route?

The Lambert-St Louis to Key Largo flight path was viewed by 57 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from St. Louis to Key Largo?

For as low as $299, Southwest can have you in Key Largo from St. Louis in 4h 15m. The distance between St. Louis and Key Largo is about 1069 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from St. Louis to Key Largo one-way?

For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $53. Users have also found prices from $65 and $89 on Frontier and American Airlines, respectively.

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

What are the cheapest flights from St. Louis to Key Largo?

On average you can expect to pay $495 for a flight from St. Louis to Key Largo. The cheapest flight overall is $174 while the most popular route, (Lambert-St Louis - Miami) is currently priced at $122.

What are the most reliable airlines from St. Louis to Key Largo?

The top 3 most reliable airlines when flying from St. Louis to Key Largo are Royal Air Maroc (100%), Envoy Air (73%) and GOL (70%).

What are the most popular airlines that fly from St. Louis to Key Largo?

Consider American Airlines, Southwest or Frontier when booking your flight. These represent the most popular airlines when flying from St. Louis to Key Largo.

What airport do you fly from for flights from St. Louis to Key Largo?

For a flight from St. Louis to Key Largo, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city. Lambert-St Louis is the only St. Louis airport and it handles 1 outbound flight to Key Largo per day. 6 airlines have flights to Key Largo from Lambert-St Louis on a regular basis.

Can I find deals for flights from St. Louis to Key Largo that include hotel bookings?

Yes. In addition to deals on St. Louis to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Key Largo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Key Largo.

Can I find deals for business class flights from St. Louis to Key Largo?

Yes. Cheapflights offers flight deals from St. Louis to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$64+ Flights from St. Louis to Key Largo

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Find cheap flights from St. Louis to Key Largo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Lambert-St Louis to Key Largo are usually found in September or October, booked 33 days in advance, depart on a Sunday or Monday and return on a Thursday

Cheap flight deals from St. Louis to Key Largo

Cheapest flights from St. Louis to Key Largo
Explore the most affordable flight options available from St. Louis to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Tue 12/3010:48 amSTL - MIA

1 stop25h 18mMultiple Airlines

Tue 1/69:59 pmMIA - STL

2 stops25h 34mMultiple Airlines

Deal found 12/14

$222

Wed 12/177:43 pmSTL - MIA

1 stop8h 36mFrontier

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/14

$233

Tue 12/3010:48 amSTL - MIA

1 stop7h 42mFrontier

Thu 1/15:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/16

$258

Wed 12/314:27 pmSTL - MIA

2 stops43h 39mMultiple Airlines

Wed 1/77:09 pmMIA - STL

1 stop20h 39mMultiple Airlines

Deal found 12/16

$264

Fri 12/1910:10 pmSTL - MIA

1 stop30h 25mFrontier

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/16

$267

Tue 12/3010:48 amSTL - MIA

1 stop7h 42mFrontier

Sun 1/45:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/15

$268

Wed 12/245:19 pmSTL - MIA

1 stop11h 16mFrontier

Thu 1/15:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/16

$271

Wed 12/317:43 pmSTL - MIA

1 stop8h 17mFrontier

Sun 1/45:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/15

$277

Sun 12/2110:57 amSTL - MIA

1 stop7h 33mFrontier

Thu 12/255:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/14

$292

Wed 12/246:00 pmSTL - MIA

Nonstop2h 57mAmerican Airlines

Thu 1/17:00 amMIA - STL

1 stop7h 14mAmerican Airlines

Deal found 12/16

$293

Tue 12/3010:48 amSTL - MIA

1 stop9h 16mMultiple Airlines

Sun 1/45:30 amMIA - STL

1 stop5h 10mMultiple Airlines

Deal found 12/16

$294

Best flights from St. Louis to Key Largo
Discover carefully curated flight deals from St. Louis to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Wed 2/254:45 pmSTL - MIA

1 stop4h 15mSouthwest

Sat 2/286:00 amMIA - STL

Nonstop3h 05mSouthwest

Deal found 12/16

$299

Sat 1/105:00 pmSTL - MIA

1 stop4h 48mDelta

Sun 1/187:15 amMIA - STL

1 stop4h 50mDelta

Deal found 12/16

$336

Wed 1/78:15 amSTL - MIA

Nonstop2h 45mSouthwest

Mon 1/124:55 pmMIA - STL

Nonstop3h 05mSouthwest

Deal found 12/16

$332

Fri 1/306:57 pmSTL - MIA

1 stop4h 54mDelta

Sat 2/77:15 amMIA - STL

1 stop5h 39mDelta

Deal found 12/16

$339

Thu 1/291:10 pmSTL - MIA

2 stops7h 50mSouthwest

Wed 2/45:20 pmMIA - STL

1 stop5h 05mSouthwest

Deal found 12/14

$344

Sat 2/710:25 amSTL - MIA

2 stops10h 10mSouthwest

Fri 2/135:55 amMIA - STL

2 stops12h 20mSouthwest

Deal found 12/15

$355

Sat 2/282:40 pmSTL - MIA

1 stop6h 35mSouthwest

Sat 3/76:40 pmMIA - STL

Nonstop3h 10mSouthwest

Deal found 12/14

$364

Sat 2/212:05 pmSTL - MIA

2 stops7h 10mSouthwest

Mon 3/26:30 amMIA - STL

2 stops8h 40mSouthwest

Deal found 12/15

$384

Fri 2/69:40 amSTL - MIA

2 stops11h 00mSouthwest

Thu 2/125:55 amMIA - STL

2 stops12h 20mSouthwest

Deal found 12/15

$385

Wed 12/3112:45 pmSTL - MIA

2 stops8h 05mSouthwest

Wed 1/76:55 amMIA - STL

2 stops9h 05mSouthwest

Deal found 12/16

$386

Thu 1/228:15 amSTL - MIA

Nonstop2h 45mSouthwest

Sun 1/256:30 amMIA - STL

2 stops8h 40mSouthwest

Deal found 12/14

$399

Last-minute flights from St. Louis to Key Largo
Discover last-minute flight deals from St. Louis to Key Largo. Data last updated December 18, 2025 and is based on user searches.

Wed 12/177:43 pmSTL - MIA

1 stop8h 36mFrontier

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/14

$233

Fri 12/1910:10 pmSTL - MIA

1 stop30h 25mFrontier

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/16

$267

Tue 12/3010:48 amSTL - MIA

1 stop25h 18mMultiple Airlines

Tue 1/69:59 pmMIA - STL

2 stops25h 34mMultiple Airlines

Deal found 12/14

$222

Wed 12/314:27 pmSTL - MIA

2 stops43h 39mMultiple Airlines

Wed 1/77:09 pmMIA - STL

1 stop20h 39mMultiple Airlines

Deal found 12/16

$264

Thu 1/110:42 amSTL - MIA

1 stop9h 22mMultiple Airlines

Tue 1/66:16 pmMIA - STL

1 stop16h 46mMultiple Airlines

Deal found 12/17

$255

Thu 1/110:42 amSTL - MIA

1 stop7h 48mFrontier

Sun 1/45:30 amMIA - STL

1 stop5h 10mFrontier

Deal found 12/16

$258

Sun 1/410:57 amSTL - MIA

1 stop25h 09mMultiple Airlines

Fri 1/99:03 pmMIA - STL

2 stops26h 30mMultiple Airlines

Deal found 12/15

$238

Wed 1/77:43 pmSTL - MIA

2 stops38h 05mFrontier

Wed 1/145:45 pmMIA - STL

2 stops29h 49mFrontier

Deal found 12/15

$246

Fri 1/93:43 pmSTL - MIA

1 stop8h 03mMultiple Airlines

Sun 1/117:00 amMIA - STL

2 stops26h 05mMultiple Airlines

Deal found 12/16

$241

Wed 1/148:32 pmSTL - MIA

1 stop13h 07mMultiple Airlines

Mon 1/198:51 pmMIA - STL

2 stops27h 42mMultiple Airlines

Deal found 12/17

$259

Thu 1/225:42 pmSTL - MIA

2 stops16h 17mFrontier

Sun 1/257:09 pmMIA - STL

1 stop12h 42mFrontier

Deal found 12/16

$247

One-way flights from St. Louis to Key Largo
Search for one-way flight options from St. Louis to Key Largo. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Wed 1/148:32 pmSTL - MIA

1 stop14h 24mMultiple Airlines

Deal found 12/16

$64

Mon 1/198:32 pmSTL - MIA

1 stop14h 24mMultiple Airlines

Deal found 12/16

$65

Sat 2/218:17 pmSTL - MIA

1 stop13h 11mFrontier

Deal found 12/17

$66

Sat 2/78:22 pmSTL - MIA

1 stop13h 37mFrontier

Deal found 12/17

$67

Sat 1/178:32 pmSTL - MIA

1 stop27h 10mFrontier

Deal found 12/16

$68

Sat 2/148:17 pmSTL - MIA

1 stop13h 11mFrontier

Deal found 12/17

$69

Thu 1/83:43 pmSTL - MIA

1 stop8h 03mFrontier

Deal found 12/16

$77

Sun 1/113:43 pmSTL - MIA

1 stop19h 13mMultiple Airlines

Deal found 12/14

$84

Wed 2/114:51 pmSTL - MIA

1 stop11h 23mFrontier

Deal found 12/15

$86

Thu 1/110:42 amSTL - MIA

1 stop7h 48mFrontier

Deal found 12/17

$87

Wed 3/1111:32 amSTL - MIA

1 stop5h 21mFrontier

Deal found 12/15

$91

Find flight deals from St. Louis to Key Largo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$222 (Kiwi.com)
One-way from	$64 (Kiwi.com)
Popular in	March
Cheapest in	September
Average price	$439

Provider with most accurate pricing for Lambert-St Louis-Miami flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Miami flights.

Search Deals

From Lambert-St Louis to Key Largo

Search Deals

One-way flight from Lambert-St Louis to Key Largo

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 2/25

4:45 pm-10:00 pm

1 stop4h 15m

Miami

Sat 2/28

6:00 am-8:05 am

Nonstop3h 05m

$299

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 1/7

8:15 am-12:00 pm

Nonstop2h 45m

Miami

Mon 1/12

4:55 pm-7:00 pm

Nonstop3h 05m

$332

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 1/10

5:00 pm-10:48 pm

1 stop4h 48m

Miami

Sun 1/18

7:15 am-11:05 am

1 stop4h 50m

$336

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 1/30

6:57 pm-12:51 am

1 stop4h 54m

Miami

Sat 2/7

7:15 am-11:54 am

1 stop5h 39m

$339

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Thu 1/29

1:10 pm-10:00 pm

2 stops7h 50m

Miami

Wed 2/4

5:20 pm-9:25 pm

1 stop5h 05m

$344

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 2/7

10:25 am-9:35 pm

2 stops10h 10m

Miami

Fri 2/13

5:55 am-5:15 pm

2 stops12h 20m

$355

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 2/28

2:40 pm-10:15 pm

1 stop6h 35m

Miami

Sat 3/7

6:40 pm-8:50 pm

Nonstop3h 10m

$364

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 2/21

2:05 pm-10:15 pm

2 stops7h 10m

Miami

Mon 3/2

6:30 am-2:10 pm

2 stops8h 40m

$384

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 2/6

9:40 am-9:40 pm

2 stops11h 00m

Miami

Thu 2/12

5:55 am-5:15 pm

2 stops12h 20m

$385

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 12/31

12:45 pm-9:50 pm

2 stops8h 05m

Miami

Wed 1/7

6:55 am-3:00 pm

2 stops9h 05m

$386

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 21 results

Best time to book a flight from St. Louis to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Key Largo

How far ahead should I book a flight from St. Louis to Key Largo?

To ensure you get the cheapest price possible for a flight from St. Louis to Key Largo, you should look to book at least 33 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from St. Louis to Key Largo?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Key Largo (average of $68). Flying from St. Louis to Key Largo in June is currently the most expensive (average of $122). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to KE9?

It’s optimal to fly from St. Louis to Key Largo in the evening. By choosing this option you can save up to 26% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from St. Louis to Key Largo?

Travelers seeking maximum savings on their St. Louis to Key Largo flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from St. Louis to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,007 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,055 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,189 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,081 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly from for flights from St. Louis to Key Largo?
For a flight from St. Louis to Key Largo, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city. Lambert-St Louis is the only St. Louis airport and it handles 1 outbound flight to Key Largo per day. 6 airlines have flights to Key Largo from Lambert-St Louis on a regular basis.
How popular is this St. Louis to Key Largo flight route?
The Lambert-St Louis to Key Largo flight path was viewed by 57 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from St. Louis to Key Largo?
For as low as $299, Southwest can have you in Key Largo from St. Louis in 4h 15m. The distance between St. Louis and Key Largo is about 1069 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from St. Louis to Key Largo one-way?
For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $53. Users have also found prices from $65 and $89 on Frontier and American Airlines, respectively.
What are the most reliable airlines from St. Louis to Key Largo?
The top 3 most reliable airlines when flying from St. Louis to Key Largo are Royal Air Maroc (100%), Envoy Air (73%) and GOL (70%).
What are the cheapest flights from St. Louis to Key Largo?
On average you can expect to pay $495 for a flight from St. Louis to Key Largo. The cheapest flight overall is $174 while the most popular route, (Lambert-St Louis - Miami) is currently priced at $122.
Can I find deals for flights from St. Louis to Key Largo that include hotel bookings?
Yes. In addition to deals on St. Louis to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Key Largo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Key Largo.
Can I find deals for business class flights from St. Louis to Key Largo?
Yes. Cheapflights offers flight deals from St. Louis to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Key Largo?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Key Largo (average of $68). Flying from St. Louis to Key Largo in June is currently the most expensive (average of $122). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Key Largo car rentals

Miami Airport car rentals

Fort Lauderdale Airport car rentals

Key West Airport car rentals

Orlando car rentals

Miami car rentals

Fort Lauderdale car rentals

Tampa car rentals

Fort Myers car rentals

Jacksonville car rentals

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Pensacola car rentals

Top 6 airlines flying from St. Louis to Key Largo

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$68	Average$147	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$113	Average$221	FlexibilityNo cancel fee	On-time62%
United Airlines	Cheapest$150	Average$433	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$172	Average$414	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$217	Average$423	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$237	Average$459	FlexibilityNo cancel fee	On-time63%

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$64+ Cheap flights from St. Louis (STL) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Key Largo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to Key Largo are usually found in September or October, booked 33 days in advance, depart on a Sunday or Monday and return on a Thursday

Cheap flight deals from St. Louis to Key Largo

Cheapest flights from St. Louis to Key LargoExplore the most affordable flight options available from St. Louis to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from St. Louis to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from St. Louis to Key Largo

Keep the following information in mind while searching for St. Louis to Key Largo flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Key Largo that are best for you.

Best time to book a flight from St. Louis to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Key Largo

How far ahead should I book a flight from St. Louis to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Key Largo. Price data was last updated on December 12, 2025.

What is the cheapest month to book a flight from St. Louis to Key Largo?

What is the cheapest time of day to fly from STL to KE9?

Find hourly flight availability from St. Louis to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

What is the cheapest day to fly from St. Louis to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Key Largo. Price data was last updated on December 16, 2024.

Reviews of airlines servicing Key Largo

Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from St. Louis to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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Alternative routes for St. Louis to Key Largo

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Top 6 airlines flying from St. Louis to Key Largo

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Cheapest flights from St. Louis to Key Largo
Explore the most affordable flight options available from St. Louis to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.