HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Irvine

$80+ Cheap flights from Medford (MFR) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — LAX
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to Irvine with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Medford to Irvine are usually found in August or October, booked 83 days in advance, depart on a Thursday or Friday and return on a Saturday

Cheap flight deals from Medford to Irvine

Keep the following information in mind while searching for Medford to Irvine flight deals. Data was last updated September 15, 2025.

Round-trip from

$143
(KAYAK)

One-way from

$80
(Kissandfly.com)

Popular in

September

Cheapest in

August

Average price

$367
From Medford to Irvine
Search Deals
One-way flight from Medford to Irvine
Search Deals
High demand for flights, 5% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Medford to Irvine

Cheapest flights from Medford to Irvine
Explore the most affordable flight options available from Medford to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This KAYAK deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/204:10 pmMFR - LAX
Nonstop1h 58mAlaska Airlines
Sun 11/239:56 pmLAX - MFR
Nonstop2h 03mAlaska Airlines
Deal found 9/13$143
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1611:53 amMFR - LAX
Nonstop2h 01mHawaiian Airlines
Mon 10/209:25 pmLAX - MFR
Nonstop2h 06mHawaiian Airlines
Deal found 9/14$147
This Hawaiian Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amMFR - LAX
Nonstop2h 02mHawaiian Airlines
Sat 11/812:53 pmLAX - MFR
Nonstop2h 05mHawaiian Airlines
Deal found 9/15$157
This KAYAK deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2312:40 pmMFR - LAX
1 stop4h 40mAlaska Airlines
Thu 10/309:00 amLAX - MFR
1 stop6h 33mAlaska Airlines
Deal found 9/14$161
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:13 pmMFR - LAX
1 stop3h 34mUnited Airlines
Tue 10/218:15 amLAX - MFR
1 stop3h 52mUnited Airlines
Deal found 9/14$172
This Alaska Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/202:41 pmMFR - LAX
1 stop6h 03mAlaska Airlines
Fri 10/242:00 pmLAX - MFR
1 stop5h 04mAlaska Airlines
Deal found 9/15$176
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:24 pmMFR - LAX
1 stop6h 40mDelta
Mon 10/137:20 pmLAX - MFR
1 stop4h 29mDelta
Deal found 9/15$177

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Medford to Irvine that are best for you.

Fly from

Medford

Fly to

Irvine

Route

Depart

Return

Price

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Fri 11/14

4:10 pm-6:08 pm

Nonstop1h 58m

Los Angeles

Tue 11/18

9:56 pm-11:59 pm

Nonstop2h 03m

$157

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Wed 2/25

7:00 am-9:00 am

Nonstop2h 00m

Los Angeles

Thu 3/5

8:55 pm-10:55 pm

Nonstop2h 00m

$157

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Wed 10/29

6:00 am-8:02 am

Nonstop2h 02m

Los Angeles

Sat 11/8

9:56 pm-11:59 pm

Nonstop2h 03m

$157

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Sat 11/15

4:10 pm-6:08 pm

Nonstop1h 58m

Los Angeles

Mon 11/17

9:56 pm-11:59 pm

Nonstop2h 03m

$157

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Sat 11/1

4:10 pm-6:08 pm

Nonstop1h 58m

Los Angeles

Mon 11/3

9:56 pm-11:59 pm

Nonstop2h 03m

$157

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Thu 11/13

4:10 pm-6:08 pm

Nonstop1h 58m

Los Angeles

Mon 11/17

9:56 pm-11:59 pm

Nonstop2h 03m

$157

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Thu 10/30

6:00 am-10:43 am

1 stop4h 43m

Los Angeles

Tue 11/4

5:20 pm-10:30 pm

1 stop5h 10m

$172

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Tue 10/14

2:13 pm-5:47 pm

1 stop3h 34m

Los Angeles

Tue 10/21

8:15 am-12:07 pm

1 stop3h 52m

$172

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Sun 9/28

5:58 am-8:08 am

Nonstop2h 10m

$80

MedfordLos Angeles

MFR - LAX

MFRLAX

Medford

Mon 10/27

8:48 am-12:57 pm

1 stop4h 09m

$88

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 16 results
1
2

Best time to book a flight from Medford to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Irvine

How far ahead should I book a flight from Medford to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Medford to Irvine. Price data was last updated on September 12, 2025.

The best time to book flights from Medford to Irvine is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Medford to Irvine?

Currently, January is the cheapest month in which you can book a flight from Medford to Irvine (average of $246). Flying from Medford to Irvine in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to IR9?

Find hourly flight availability from Medford to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Medford to Irvine, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Medford to Irvine?

Use this chart to determine the cheapest time to fly round-trip from Medford to Irvine. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Medford to Irvine flight should consider departing on Sunday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Medford to Irvine

Explore weekly flight availability from Medford to Irvine. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from MFR to IR9 are scheduled on a Monday (8 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (6 on average).

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated September 15, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Hawaiian Airlines, and United Airlines from Medford to Irvine by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.0

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.0

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Hawaiian Airlines
7.8
Good
2,723 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.0

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,929 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.0

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.0

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Allegiant Air
7.2
Good
699 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.0

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Medford to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Irvine?

    Medford (MFR), located 3.0 mi from the city center, is the airport you fly out of when you book flights from Medford to Irvine. 7 airlines have flights from Medford to Irvine on a regular basis. Booking flights from Medford to Irvine should not be difficult; the airport handles an average of 7 outbound flights to Irvine per day.

  • How popular is this Medford to Irvine flight route?

    Flights from Medford to Irvine have been viewed 6 times in the past calendar month.

  • How long is the flight from Medford to Irvine?

    Departing from Medford to Irvine will take you 1h 58m. Airlines will cover a distance of 630 mi. All flights are typically nonstop.

  • What are the cheapest airlines to fly from Medford to Irvine one-way?

    The cheapest airlines for a one-way flight from Medford to Irvine are Alaska Airlines ($80), Hawaiian Airlines ($88), and Delta ($89).

  • What are the most reliable airlines from Medford to Irvine?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Medford to Irvine on time: Iberia (91%), Qatar Airways (89%), American Airlines (86%).

  • What are the cheapest flights from Medford to Irvine?

    The cheapest flight price from Medford to Irvine is $66. On average you can expect to pay $317. The most popular route, (Medford - Los Angeles), can usually be booked for $143.

  • Can I find deals for flights from Medford to Irvine that include hotel bookings?

    Yes. In addition to deals on Medford to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Irvine.

  • Can I find deals for business class flights from Medford to Irvine?

    Yes. Cheapflights offers flight deals from Medford to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Irvine?

    Currently, January is the cheapest month in which you can book a flight from Medford to Irvine (average of $246). Flying from Medford to Irvine in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Medford to Irvine

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Las Vegas flights
Portland to Los Angeles flights
Portland to Ontario flights
Portland to San Diego flights
Portland to Santa Ana flights
Portland to Palm Springs flights
Portland to San Francisco flights
Boise to Las Vegas flights
Portland to Oakland flights
Boise to Los Angeles flights
Portland to Burbank flights
Eugene to Los Angeles flights
Portland to San Jose flights
Portland to Sacramento flights
Boise to San Diego flights
Portland to Reno flights
Eugene to Las Vegas flights
Eugene to San Diego flights
Boise to Burbank flights
Boise to Santa Ana flights
Boise to San Francisco flights
Redmond to Las Vegas flights
Medford to Los Angeles flights
Boise to Sacramento flights
Portland to Santa Barbara flights
Eugene to Ontario flights
Eugene to San Francisco flights
Redmond to Los Angeles flights
Portland to Long Beach flights
Portland to Fresno flights
Portland to Santa Rosa flights
Boise to Ontario flights
Portland to San Luis Obispo flights
Redmond to San Francisco flights
Boise to San Jose flights
Medford to San Francisco flights
Boise to Palm Springs flights
Medford to San Diego flights
Medford to Las Vegas flights
Medford to Ontario flights
Redmond to San Diego flights
Eugene to Sacramento flights
Eugene to Palm Springs flights
Redmond to Palm Springs flights
Boise to Fresno flights
Boise to Reno flights
Medford to Santa Ana flights
Boise to Oakland flights
Portland to Medford flights
Eugene to San Luis Obispo flights

Top 7 airlines flying from Medford to Irvine

Discover the top 7 airlines that operate flights from Medford to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$55Average$188FlexibilityNo cancel feeOn-time88%
Avelo AirlinesCheapest$68Average$156FlexibilityNo cancel feeOn-timeN/A
Hawaiian AirlinesCheapest$128Average$249FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$175Average$329FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$181Average$360FlexibilityNo cancel feeOn-time69%
DeltaCheapest$183Average$325FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$230Average$557FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.