$132+ Cheap flights from Mississippi to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — DSM
May 19 — May 261
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to Iowa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Mississippi to IowaExplore the most affordable flight options available from Mississippi to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
Explore the most affordable flight options available from Mississippi to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:30 am
MEM
- MLI
1 stop4h 50m
Delta
Tue 6/165:17 pm
MLI
- MEM
1 stop6h 09m
Delta
Deal found 4/18![Delta logo]()
$261
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:56 pm
MEM
- MLI
2 stops8h 56m
American Airlines
Tue 6/164:45 pm
MLI
- MEM
1 stop5h 40m
American Airlines
Deal found 4/18![American Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:49 pm
MEM
- DSM
1 stop4h 43m
Delta
Wed 6/106:39 pm
DSM
- MEM
1 stop4h 47m
Delta
Deal found 4/17![Delta logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:24 am
MEM
- DSM
1 stop15h 00m
Multiple Airlines
Thu 6/113:37 pm
DSM
- MEM
2 stops15h 56m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:54 pm
MEM
- MLI
1 stop4h 40m
Delta
Tue 6/165:17 pm
MLI
- MEM
1 stop6h 09m
Delta
Deal found 4/18![Delta logo]()
$276
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MEM
- OMA
1 stop4h 15m
Delta
Thu 5/286:34 am
OMA
- MEM
1 stop4h 57m
Delta
Deal found 4/17![Delta logo]()
$277
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
MEM
- DSM
1 stop6h 24m
Delta
Wed 6/106:03 pm
DSM
- MEM
1 stop4h 18m
Delta
Deal found 4/17![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MEM
- DSM
2 stops8h 05m
Southwest
Tue 5/193:15 pm
DSM
- MEM
1 stop7h 35m
Southwest
Deal found 4/14![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:30 am
MEM
- MLI
1 stop4h 50m
Delta
Thu 6/185:56 am
MLI
- MEM
1 stop4h 41m
Delta
Deal found 4/18![Delta logo]()
$285
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
MEM
- DSM
1 stop6h 24m
Delta
Sat 6/66:15 am
DSM
- MEM
1 stop5h 01m
Delta
Deal found 4/17![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
MEM
- DSM
1 stop6h 30m
Southwest
Sat 5/235:35 am
DSM
- MEM
2 stops8h 25m
Southwest
Deal found 4/16![Southwest logo]()
$290
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:15 am
MEM
- MLI
1 stop5h 09m
Delta
Mon 6/155:17 pm
MLI
- MEM
1 stop6h 09m
Delta
Deal found 4/18![Delta logo]()
$291
Best flights from Mississippi to IowaDiscover carefully curated flight deals from Mississippi to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
Discover carefully curated flight deals from Mississippi to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:20 pm
MEM
- DSM
1 stop7h 25m
United Airlines
Tue 5/196:15 am
DSM
- MEM
1 stop4h 39m
United Airlines
Deal found 4/14![United Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:15 am
MEM
- MLI
1 stop5h 09m
Delta
Tue 6/165:17 pm
MLI
- MEM
1 stop6h 09m
Delta
Deal found 4/18![Delta logo]()
$276
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
MEM
- DSM
1 stop6h 30m
Southwest
Sat 5/235:35 am
DSM
- MEM
2 stops8h 25m
Southwest
Deal found 4/16![Southwest logo]()
$290
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:29 pm
MOB
- OMA
2 stops7h 30m
American Airlines
Mon 6/295:16 am
OMA
- MOB
1 stop6h 09m
American Airlines
Deal found 4/18![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:30 am
MEM
- DSM
1 stop6h 07m
Delta
Sat 5/237:01 am
DSM
- MEM
1 stop4h 30m
Delta
Deal found 4/16![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
MEM
- DSM
1 stop6h 24m
Delta
Wed 6/106:03 pm
DSM
- MEM
1 stop4h 18m
Delta
Deal found 4/17![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:25 am
MEM
- DSM
2 stops7h 55m
Southwest
Sat 5/305:35 am
DSM
- MEM
1 stop6h 05m
Southwest
Deal found 4/15![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:45 am
MEM
- MLI
1 stop4h 09m
United Airlines
Wed 9/26:50 pm
MLI
- MEM
1 stop4h 56m
United Airlines
Deal found 4/14![United Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:25 pm
MEM
- DSM
2 stops6h 45m
Southwest
Tue 5/195:30 am
DSM
- MEM
2 stops12h 05m
Southwest
Deal found 4/14![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:16 pm
MEM
- DSM
1 stop7h 07m
United Airlines
Sat 5/165:00 am
DSM
- MEM
1 stop5h 54m
United Airlines
Deal found 4/14![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:16 pm
BTR
- OMA
1 stop5h 10m
American Airlines
Tue 6/234:56 pm
OMA
- BTR
1 stop6h 03m
American Airlines
Deal found 4/14![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:54 pm
MEM
- MLI
1 stop4h 40m
Delta
Wed 6/175:56 am
MLI
- MEM
2 stops15h 36m
Delta
Deal found 4/18![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MEM
- OMA
1 stop5h 00m
Southwest
Thu 5/284:35 pm
OMA
- MEM
1 stop6h 50m
Southwest
Deal found 4/18![Southwest logo]()
$352
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:23 pm
MEM
- OMA
1 stop8h 19m
United Airlines
Thu 5/287:55 am
OMA
- MEM
1 stop6h 47m
United Airlines
Deal found 4/18![United Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:42 pm
GPT
- DSM
2 stops11h 17m
American Airlines
Wed 5/271:48 pm
DSM
- GPT
2 stops10h 13m
American Airlines
Deal found 4/16![American Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
BTR
- OMA
1 stop4h 43m
Delta
Mon 5/47:04 am
OMA
- BTR
1 stop5h 46m
Delta
Deal found 4/15![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:20 pm
MEM
- OMA
1 stop7h 09m
United Airlines
Sat 5/161:50 pm
OMA
- MEM
1 stop7h 04m
United Airlines
Deal found 4/14![United Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/224:29 pm
MOB
- OMA
1 stop7h 53m
American Airlines
Mon 6/294:56 pm
OMA
- MOB
1 stop7h 03m
American Airlines
Deal found 4/18![American Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:25 am
MEM
- OMA
2 stops11h 25m
Southwest
Sat 5/236:20 am
OMA
- MEM
2 stops7h 40m
Southwest
Deal found 4/16![Southwest logo]()
$392
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:01 pm
MOB
- OMA
1 stop4h 57m
Delta
Tue 5/126:35 pm
OMA
- MOB
1 stop4h 53m
Delta
Deal found 4/15![Delta logo]()
$360
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:22 am
MEM
- MLI
1 stop5h 15m
United Airlines
Mon 5/253:47 pm
MLI
- MEM
1 stop6h 17m
United Airlines
Deal found 4/18![United Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
GPT
- DSM
2 stops7h 48m
American Airlines
Mon 5/112:18 pm
DSM
- GPT
2 stops9h 40m
American Airlines
Deal found 4/15![American Airlines logo]()
$432
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MEM
- OMA
2 stops11h 42m
United Airlines
Wed 5/139:10 am
OMA
- MEM
1 stop5h 17m
United Airlines
Deal found 4/17![United Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:06 pm
MOB
- OMA
1 stop5h 04m
Delta
Mon 5/46:37 pm
OMA
- MOB
1 stop4h 21m
Delta
Deal found 4/14![Delta logo]()
$365
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:10 am
JAN
- OMA
1 stop4h 30m
Southwest
Sun 7/125:30 pm
OMA
- JAN
1 stop4h 30m
Southwest
Deal found 4/14![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:58 pm
JAN
- OMA
1 stop5h 40m
United Airlines
Wed 5/136:15 am
OMA
- JAN
1 stop5h 01m
United Airlines
Deal found 4/13![United Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
MEM
- OMA
1 stop4h 12m
Delta
Mon 8/172:00 pm
OMA
- MEM
1 stop7h 07m
Delta
Deal found 4/18![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/274:21 pm
JAN
- OMA
2 stops7h 38m
American Airlines
Tue 6/305:04 pm
OMA
- JAN
1 stop6h 50m
American Airlines
Deal found 4/14![American Airlines logo]()
$473
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:10 am
JAN
- OMA
1 stop4h 30m
Southwest
Mon 7/205:25 pm
OMA
- JAN
1 stop4h 30m
Southwest
Deal found 4/17![Southwest logo]()
$438
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:20 pm
MEM
- OMA
1 stop4h 39m
Delta
Mon 8/1710:55 am
OMA
- MEM
1 stop6h 37m
Delta
Deal found 4/14![Delta logo]()
$387
Last-minute flights from Mississippi to IowaDiscover last-minute flight deals from Mississippi to Iowa. Data last updated April 19, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Iowa. Data last updated April 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:22 am
MOB
- OMA
1 stop6h 40m
American Airlines
Tue 5/129:48 am
OMA
- MOB
1 stop6h 31m
American Airlines
Deal found 4/18![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:00 pm
BTR
- OMA
1 stop5h 38m
United Airlines
Sun 5/106:00 am
OMA
- BTR
2 stops7h 23m
United Airlines
Deal found 4/16![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:20 pm
MEM
- DSM
1 stop7h 25m
United Airlines
Tue 5/196:15 am
DSM
- MEM
1 stop4h 39m
United Airlines
Deal found 4/14![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MEM
- DSM
2 stops8h 05m
Southwest
Tue 5/193:15 pm
DSM
- MEM
1 stop7h 35m
Southwest
Deal found 4/14![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:30 am
MEM
- DSM
1 stop6h 07m
Delta
Sat 5/237:01 am
DSM
- MEM
1 stop4h 30m
Delta
Deal found 4/16![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
MEM
- DSM
1 stop6h 30m
Southwest
Sat 5/235:35 am
DSM
- MEM
2 stops8h 25m
Southwest
Deal found 4/16![Southwest logo]()
$290
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:03 am
MEM
- OMA
1 stop7h 18m
American Airlines
Sat 5/237:47 pm
OMA
- MEM
1 stop4h 17m
American Airlines
Deal found 4/16![American Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MEM
- OMA
1 stop4h 15m
Delta
Thu 5/286:34 am
OMA
- MEM
1 stop4h 57m
Delta
Deal found 4/17![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:03 pm
GPT
- DSM
1 stop6h 56m
American Airlines
Wed 5/274:48 pm
DSM
- GPT
1 stop6h 13m
American Airlines
Deal found 4/16![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:01 pm
MEM
- OMA
1 stop5h 21m
American Airlines
Mon 5/257:47 pm
OMA
- MEM
1 stop4h 17m
American Airlines
Deal found 4/17![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:25 am
MEM
- DSM
2 stops7h 55m
Southwest
Sat 5/305:35 am
DSM
- MEM
1 stop6h 05m
Southwest
Deal found 4/15![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:23 pm
MEM
- DSM
1 stop7h 12m
United Airlines
Sat 5/305:00 am
DSM
- MEM
1 stop6h 05m
United Airlines
Deal found 4/15![United Airlines logo]()
$328
One-way flights from Mississippi to IowaSearch for one-way flight options from Mississippi to Iowa. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
Search for one-way flight options from Mississippi to Iowa. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:40 am
MEM
- OMA
1 stop5h 03m
American Airlines
Deal found 4/14![American Airlines logo]()
$132
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
MEM
- DSM
1 stop6h 24m
Delta
Deal found 4/15![Delta logo]()
$136
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:25 pm
MEM
- OMA
2 stops6h 55m
Southwest
Deal found 4/14![Southwest logo]()
$137
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
MEM
- OMA
1 stop6h 25m
Delta
Deal found 4/14![Delta logo]()
$146
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:20 pm
MEM
- DSM
2 stops9h 50m
Southwest
Deal found 4/15![Southwest logo]()
$171
This deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:02 am
MEM
- OMA
1 stop5h 19m
United Airlines
Deal found 4/16![United Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:51 pm
MEM
- OMA
2 stops23h 43m
Frontier
Deal found 4/14![Frontier logo]()
$199
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:23 pm
JAN
- OMA
1 stop4h 35m
Delta
Deal found 4/16![Delta logo]()
$204
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:58 pm
JAN
- OMA
2 stops9h 52m
United Airlines
Deal found 4/16![United Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:45 am
JAN
- OMA
2 stops7h 35m
Southwest
Deal found 4/14![Southwest logo]()
$230
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:03 am
BTR
- OMA
1 stop6h 17m
Delta
Deal found 4/14![Delta logo]()
$234
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:32 pm
BTR
- OMA
1 stop5h 00m
American Airlines
Deal found 4/16![American Airlines logo]()
$244
Find flight deals from Mississippi to Iowa
Keep the following information in mind while searching for Mississippi to Iowa flight deals. Data was last updated April 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (Delta) |
One-way from | $132 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from Mississippi to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisDes Moines
MEM - DSM
MEMDSM
Memphis
Tue 5/12
3:20 pm-10:45 pm
1 stop7h 25m
Des Moines
Tue 5/19
6:15 am-10:54 am
1 stop4h 39m
$271
MemphisMoline
MEM - MLI
MEMMLI
Memphis
Thu 6/11
5:15 am-10:24 am
1 stop5h 09m
Moline Quad-City
Tue 6/16
5:17 pm-11:26 pm
1 stop6h 09m
$276
MemphisDes Moines
MEM - DSM
MEMDSM
Memphis
Sat 5/16
7:30 am-1:37 pm
1 stop6h 07m
Des Moines
Sat 5/23
7:01 am-11:31 am
1 stop4h 30m
$278
MemphisDes Moines
MEM - DSM
MEMDSM
Memphis
Mon 6/1
6:00 am-12:24 pm
1 stop6h 24m
Des Moines
Wed 6/10
6:03 pm-10:21 pm
1 stop4h 18m
$278
MemphisDes Moines
MEM - DSM
MEMDSM
Memphis
Sat 5/16
5:00 am-11:30 am
1 stop6h 30m
Des Moines
Sat 5/23
5:35 am-2:00 pm
2 stops8h 25m
$290
MobileOmaha
MOB - OMA
MOBOMA
Mobile
Tue 6/23
4:29 pm-11:59 pm
2 stops7h 30m
Omaha Eppley Airfield
Mon 6/29
5:16 am-11:25 am
1 stop6h 09m
$324
MemphisDes Moines
MEM - DSM
MEMDSM
Memphis
Sat 5/23
5:25 am-1:20 pm
2 stops7h 55m
Des Moines
Sat 5/30
5:35 am-11:40 am
1 stop6h 05m
$325
MemphisMoline
MEM - MLI
MEMMLI
Memphis
Sat 8/29
5:45 am-9:54 am
1 stop4h 09m
Moline Quad-City
Wed 9/2
6:50 pm-11:46 pm
1 stop4h 56m
$331
MemphisDes Moines
MEM - DSM
MEMDSM
Memphis
Tue 5/12
3:25 pm-10:10 pm
2 stops6h 45m
Des Moines
Tue 5/19
5:30 am-5:35 pm
2 stops12h 05m
$339
MemphisMoline
MEM - MLI
MEMMLI
Memphis
Fri 6/12
5:54 pm-10:34 pm
1 stop4h 40m
Moline Quad-City
Wed 6/17
5:56 am-9:32 pm
2 stops15h 36m
$339
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Mississippi to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Mississippi with our price prediction graph.
MEM-OMA
MEM-DSM
JAN-OMA
BTR-OMA
GTR-OMA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Iowa
USMS-USIA
MEM-OMA
MEM-DSM
JAN-OMA
BTR-OMA
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated April 19, 2026.
Read through reviews of airlines operating flights from Mississippi to Iowa, such as Delta and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Mississippi to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to Iowa by cabin class
Find flights from Mississippi to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and Iowa flights
Browse other Mississippi and Iowa flight options. Last updated on April 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Iowa
Find the right flight back to Mississippi after your stay in Iowa
Mississippi to Iowa flights
Consider these flights traveling from Mississippi to Iowa.
Top 2 airlines flying from Mississippi to Iowa
Discover the top 2 airlines that operate flights from Mississippi to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$124 | Average$268 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$326 | FlexibilityNo cancel fee | On-time71% |