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$83+ Cheap flights from Mississippi to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — DSM
dic. 24 — dic. 311
mié. 12/24
mié. 12/31
1 adult, Economy
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Cheap flight deals from Mississippi to Iowa

Keep the following information in mind while searching for Mississippi to Iowa flight deals. Data was last updated noviembre 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(Delta)

One-way from

$83
(Trip.com)
Provider with most accurate pricing for Jackson-Evers Intl-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Des Moines flights.
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From Mississippi to Iowa
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One-way flight from Mississippi to Iowa
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Find flight deals from Mississippi to Iowa

Cheapest flights from Mississippi to Iowa
Explore the most affordable flight options available from Mississippi to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 24, 2025.

This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/252:18 pmBTR - OMA
1 stop4h 18mAmerican Airlines
mar. 12/305:04 amOMA - BTR
1 stop4h 35mAmerican Airlines
Deal found 11/24$249
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/134:41 pmGPT - OMA
1 stop6h 47mAmerican Airlines
jue. 12/185:34 pmOMA - GPT
1 stop6h 38mAmerican Airlines
Deal found 11/21$249
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/187:11 amBTR - DSM
1 stop6h 10mAmerican Airlines
jue. 1/15:39 pmDSM - BTR
1 stop4h 58mAmerican Airlines
Deal found 11/24$249
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/167:20 amBTR - DSM
2 stops9h 05mAmerican Airlines
vie. 1/22:07 pmDSM - BTR
1 stop5h 50mAmerican Airlines
Deal found 11/23$254
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/910:28 amMOB - OMA
1 stop6h 59mAmerican Airlines
sáb. 12/136:02 pmOMA - MOB
1 stop6h 05mAmerican Airlines
Deal found 11/23$279
This Delta deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/55:55 amMEM - CID
1 stop5h 47mDelta
mar. 12/95:50 amCID - MEM
1 stop5h 52mDelta
Deal found 11/22$279
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/315:00 amMEM - DSM
1 stop8h 21mAmerican Airlines
dom. 1/46:52 pmDSM - MEM
1 stop6h 52mAmerican Airlines
Deal found 11/24$289
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/52:00 pmBTR - OMA
2 stops9h 00mUnited Airlines
dom. 12/76:00 amOMA - BTR
1 stop7h 14mUnited Airlines
Deal found 11/23$314
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/93:01 pmMEM - CID
1 stop4h 01mUnited Airlines
sáb. 12/138:00 amCID - MEM
1 stop6h 43mUnited Airlines
Deal found 11/23$319
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/249:15 amMEM - OMA
1 stop5h 30mAmerican Airlines
mié. 12/319:35 amOMA - MEM
1 stop6h 47mAmerican Airlines
Deal found 11/24$323
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/53:16 pmMEM - DSM
1 stop18h 32mMultiple Airlines
dom. 12/74:21 pmDSM - MEM
2 stops28h 06mMultiple Airlines
Deal found 11/23$324
This United Airlines deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/259:35 amBTR - OMA
2 stops12h 23mUnited Airlines
mar. 12/306:10 amOMA - BTR
1 stop5h 15mUnited Airlines
Deal found 11/22$345

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 24, 2025.
Use the filters below to find and compare flights from Mississippi to Iowa that are best for you.

Fly from

Mississippi

Fly to

Iowa

Route

Depart

Return

Price

MemphisMoline

MEM - MLI

MEMMLI

Memphis

sáb. 2/21

5:42 pm-10:32 pm

1 stop4h 50m

Moline Quad-City

mar. 2/24

5:00 pm-11:19 pm

1 stop6h 19m

$229

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

lun. 1/12

5:22 pm-10:29 pm

1 stop5h 07m

Des Moines

mar. 1/13

5:16 pm-11:18 pm

1 stop6h 02m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

jue. 1/8

5:50 am-10:19 am

1 stop4h 29m

Des Moines

mié. 1/14

6:24 am-11:34 am

1 stop5h 10m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mié. 1/7

6:10 am-11:24 am

1 stop5h 14m

Des Moines

mié. 1/14

4:21 pm-10:40 pm

1 stop6h 19m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mié. 1/7

5:22 pm-10:29 pm

1 stop5h 07m

Des Moines

lun. 1/12

5:16 pm-11:18 pm

1 stop6h 02m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

lun. 1/12

5:50 am-10:19 am

1 stop4h 29m

Des Moines

lun. 1/12

4:21 pm-10:40 pm

1 stop6h 19m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar. 1/6

5:50 am-10:19 am

1 stop4h 29m

Des Moines

jue. 1/8

6:24 am-11:34 am

1 stop5h 10m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

jue. 1/8

6:00 am-12:14 pm

1 stop6h 14m

Des Moines

mar. 1/13

11:26 am-4:16 pm

1 stop4h 50m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

lun. 1/12

5:50 am-10:19 am

1 stop4h 29m

Des Moines

mié. 1/14

5:16 pm-11:18 pm

1 stop6h 02m

$231

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mié. 1/7

5:22 pm-10:29 pm

1 stop5h 07m

Des Moines

mar. 1/13

11:26 am-4:16 pm

1 stop4h 50m

$231

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Showing 1-10 of 52 results
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Best time to book a flight from Mississippi to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Iowa

What is the cheapest time of day to fly from MS to IA?

Find hourly flight availability from Mississippi to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 24, 2025.

When flying from Mississippi to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 38% versus a flight at noon.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated noviembre 24, 2025.
Read through reviews of airlines operating flights from Mississippi to Iowa, such as Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,997 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,997 reviews
Delta
7.9
Good
7,997 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Iowa?

    For as low as $249, Delta can have you in Iowa from Mississippi in 4h 18m. Airlines will cover a distance of 789 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Iowa one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $136. However, be on the lookout for offers from United Airlines and Allegiant Air, as they are both options that can get you from Mississippi to Iowa for a low price.

  • Can I find deals for flights from Mississippi to Iowa that include hotel bookings?

    Yes. In addition to deals on Mississippi to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Iowa.

  • Can I find deals for business class flights from Mississippi to Iowa?

    Yes. Cheapflights offers flight deals from Mississippi to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to Iowa

Discover the top airline that operate flights from Mississippi to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$124Average$254FlexibilityNo cancel feeOn-timeN/A

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