HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$66+ Cheap flights from Mississippi to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — DSM
nov. 22 — nov. 291
sáb. 11/22
sáb. 11/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to Iowa

Keep the following information in mind while searching for Mississippi to Iowa flight deals. Data was last updated octubre 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$229
(American Airlines)

One-way from

$66
(Trip.com)
Provider with most accurate pricing for Jackson-Evers Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Des Moines flights.
Search Deals
From Mississippi to Iowa
Search Deals
One-way flight from Mississippi to Iowa
Search Deals

Find flight deals from Mississippi to Iowa

Cheapest flights from Mississippi to Iowa
Explore the most affordable flight options available from Mississippi to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 23, 2025.

This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/207:00 amMEM - CID
1 stop5h 41mAmerican Airlines
dom. 11/239:52 amCID - MEM
1 stop5h 19mAmerican Airlines
Deal found 10/21$229
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:00 amMEM - CID
1 stop5h 48mDelta
sáb. 11/155:54 amCID - MEM
1 stop5h 49mDelta
Deal found 10/22$234
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/410:35 amMEM - OMA
1 stop4h 55mSouthwest
mié. 12/103:40 pmOMA - MEM
1 stop6h 45mSouthwest
Deal found 10/22$235
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/42:55 pmMEM - CID
1 stop6h 34mUnited Airlines
lun. 11/105:26 pmCID - MEM
1 stop4h 32mUnited Airlines
Deal found 10/21$239
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/255:15 pmGPT - OMA
1 stop4h 52mUnited Airlines
jue. 11/278:15 amOMA - GPT
1 stop5h 05mUnited Airlines
Deal found 10/22$249
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/56:10 pmGPT - OMA
1 stop5h 20mAmerican Airlines
dom. 11/96:11 amOMA - GPT
1 stop6h 12mAmerican Airlines
Deal found 10/21$259
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/73:08 pmBTR - DSM
1 stop8h 22mAmerican Airlines
dom. 11/95:00 amDSM - BTR
1 stop4h 50mAmerican Airlines
Deal found 10/21$259
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/611:52 amGPT - OMA
1 stop6h 57mUnited Airlines
lun. 11/106:00 amOMA - GPT
2 stops7h 20mUnited Airlines
Deal found 10/22$264
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/75:07 amBTR - DSM
2 stops11h 05mUnited Airlines
dom. 11/96:05 amDSM - BTR
1 stop5h 13mUnited Airlines
Deal found 10/21$264
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/306:00 amMEM - CID
1 stop5h 45mDelta
lun. 11/34:23 pmCID - MEM
1 stop5h 33mDelta
Deal found 10/21$269
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/66:46 amMEM - CID
1 stop6h 14mAmerican Airlines
lun. 11/105:55 pmCID - MEM
1 stop4h 46mAmerican Airlines
Deal found 10/21$289
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/42:07 pmMEM - CID
2 stops8h 34mDelta
lun. 11/104:22 pmCID - MEM
1 stop6h 11mDelta
Deal found 10/21$294

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 23, 2025.
Use the filters below to find and compare flights from Mississippi to Iowa that are best for you.

Fly from

Mississippi

Fly to

Iowa

Route

Depart

Return

Price

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

jue. 11/20

7:00 am-12:41 pm

1 stop5h 41m

Cedar Rapids

dom. 11/23

9:52 am-3:11 pm

1 stop5h 19m

$229

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

jue. 11/20

6:00 am-11:48 am

1 stop5h 48m

Cedar Rapids

dom. 11/23

12:29 pm-11:04 pm

2 stops10h 35m

$234

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

dom. 11/9

6:00 am-11:48 am

1 stop5h 48m

Cedar Rapids

sáb. 11/15

5:54 am-11:43 am

1 stop5h 49m

$234

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

lun. 11/10

5:55 pm-11:05 pm

1 stop5h 10m

Cedar Rapids

dom. 11/16

6:44 pm-12:02 am

1 stop5h 18m

$234

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

dom. 11/9

6:46 am-10:59 am

1 stop4h 13m

Cedar Rapids

dom. 11/16

6:44 pm-12:02 am

1 stop5h 18m

$234

MemphisOmaha

MEM - OMA

MEMOMA

Memphis

jue. 12/4

10:35 am-3:30 pm

1 stop4h 55m

Omaha Eppley Airfield

mié. 12/10

3:40 pm-10:25 pm

1 stop6h 45m

$235

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

mar. 11/4

2:55 pm-9:29 pm

1 stop6h 34m

Cedar Rapids

lun. 11/10

5:26 pm-9:58 pm

1 stop4h 32m

$239

GulfportOmaha

GPT - OMA

GPTOMA

Gulfport Biloxi Regional

mar. 11/25

5:15 pm-10:07 pm

1 stop4h 52m

Omaha Eppley Airfield

jue. 11/27

8:15 am-1:20 pm

1 stop5h 05m

$249

MobileOmaha

MOB - OMA

MOBOMA

Mobile

mié. 4/15

7:15 pm-11:55 pm

1 stop4h 40m

Omaha Eppley Airfield

sáb. 4/18

5:35 am-11:29 am

1 stop5h 54m

$249

Baton RougeMoline

BTR - MLI

BTRMLI

Baton Rouge Ryan

sáb. 2/21

5:00 pm-10:34 pm

1 stop5h 34m

Moline Quad-City

mar. 2/24

5:00 pm-10:04 pm

1 stop5h 04m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/23

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Mississippi to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Iowa

What is the cheapest time of day to fly from MS to IA?

Find hourly flight availability from Mississippi to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 23, 2025.

When flying from Mississippi to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 38% versus a flight at noon.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated octubre 23, 2025.
Read through reviews of airlines operating flights from Mississippi to Iowa, such as Delta and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,982 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,982 reviews
Delta
7.9
Good
7,982 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,982 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Iowa?

    For as low as $235, American Airlines can have you in Iowa from Mississippi in 4h 55m. Airlines will cover a distance of 538 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Iowa one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $99. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Mississippi to Iowa for a low price.

  • Can I find deals for flights from Mississippi to Iowa that include hotel bookings?

    Yes. In addition to deals on Mississippi to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Iowa.

  • Can I find deals for business class flights from Mississippi to Iowa?

    Yes. Cheapflights offers flight deals from Mississippi to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Miami flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Fort Lauderdale flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to Orlando flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Dallas/Fort Worth flights
Newark to Miami flights
LaGuardia to Dallas/Fort Worth flights
LaGuardia to Miami flights
San Francisco to John F Kennedy Intl flights
Newark to Orlando flights
Dallas/Fort Worth to Las Vegas flights
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Newark flights
Los Angeles to Seattle flights
John F Kennedy Intl to San Francisco flights
Newark to Dallas/Fort Worth flights
Los Angeles to Newark flights
Dallas/Fort Worth to Los Angeles flights
O'Hare Intl to John F Kennedy Intl flights
Seattle to Los Angeles flights
Los Angeles to San Francisco flights
San Francisco to Los Angeles flights
Los Angeles to Dallas/Fort Worth flights
Seattle to Las Vegas flights
LaGuardia to Orlando flights
Los Angeles to LaGuardia flights
San Francisco to Las Vegas flights
Dallas/Fort Worth to O'Hare Intl flights
Newark to Los Angeles flights
Newark to Hobby flights
Atlanta to John F Kennedy Intl flights
O'Hare Intl to Las Vegas flights
San Francisco to Newark flights
Hobby to John F Kennedy Intl flights
John F Kennedy Intl to Hobby flights
John F Kennedy Intl to West Palm Beach flights
John F Kennedy Intl to Atlanta flights
Dulles Intl to Dallas/Fort Worth flights
Newark to Las Vegas flights
John F Kennedy Intl to Sky Harbor Intl flights
Hobby to Newark flights
O'Hare Intl to LaGuardia flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to Sky Harbor Intl flights
Los Angeles to Honolulu flights

Top 2 airlines flying from Mississippi to Iowa

Discover the top 2 airlines that operate flights from Mississippi to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$124Average$254FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$358FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.