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$67+ Cheap flights from Mississippi to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — DSM
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from Mississippi to Iowa

Keep the following information in mind while searching for Mississippi to Iowa flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$67
(Kiwi.com)
Provider with most accurate pricing for Jackson-Evers Intl-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Des Moines flights.
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From Mississippi to Iowa
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One-way flight from Mississippi to Iowa
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Find flight deals from Mississippi to Iowa

Cheapest flights from Mississippi to Iowa
Explore the most affordable flight options available from Mississippi to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:28 amMEM - DSM
1 stop8h 10mFrontier
Sun 11/238:19 pmDSM - MEM
1 stop22h 45mFrontier
Deal found 11/12$164
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:28 amMEM - DSM
1 stop8h 10mMultiple Airlines
Sun 11/238:19 pmDSM - MEM
2 stops24h 13mMultiple Airlines
Deal found 11/12$224
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:17 amMOB - OMA
1 stop7h 56mAmerican Airlines
Fri 1/93:07 pmOMA - MOB
1 stop8h 09mAmerican Airlines
Deal found 11/13$249
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:03 pmBTR - DSM
1 stop4h 26mUnited Airlines
Sun 12/148:15 amDSM - BTR
1 stop4h 59mUnited Airlines
Deal found 11/11$249
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:07 amBTR - DSM
2 stops10h 56mDelta
Sun 12/142:16 pmDSM - BTR
1 stop5h 41mDelta
Deal found 11/11$254
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:03 pmGPT - OMA
1 stop6h 11mDelta
Thu 11/274:00 pmOMA - GPT
1 stop6h 07mDelta
Deal found 11/10$264
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:39 amBTR - DSM
1 stop5h 52mDelta
Sun 12/1410:20 amDSM - BTR
2 stops9h 37mDelta
Deal found 11/11$279
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:43 amMEM - CID
1 stop5h 46mAmerican Airlines
Mon 12/17:57 pmCID - MEM
1 stop4h 02mAmerican Airlines
Deal found 11/12$279
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:39 amBTR - DSM
2 stops8h 37mDelta
Sun 12/1410:20 amDSM - BTR
2 stops9h 37mDelta
Deal found 11/11$284
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:12 pmMEM - OMA
1 stop6h 47mDelta
Tue 12/165:55 pmOMA - MEM
1 stop4h 44mDelta
Deal found 11/11$297
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/910:29 amMEM - OMA
2 stops12h 01mAmerican Airlines
Tue 12/165:00 amOMA - MEM
1 stop5h 37mAmerican Airlines
Deal found 11/11$302
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1312:48 pmMEM - OMA
1 stop5h 13mDelta
Mon 12/155:55 pmOMA - MEM
1 stop4h 44mDelta
Deal found 11/13$309

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Mississippi to Iowa that are best for you.

Fly from

Mississippi

Fly to

Iowa

Route

Depart

Return

Price

MobileOmaha

MOB - OMA

MOBOMA

Mobile

Thu 12/11

5:17 am-1:13 pm

1 stop7h 56m

Omaha Eppley Airfield

Mon 12/15

3:10 pm-11:10 pm

1 stop8h 00m

$249

MobileOmaha

MOB - OMA

MOBOMA

Mobile

Wed 4/15

7:15 pm-11:55 pm

1 stop4h 40m

Omaha Eppley Airfield

Sat 4/18

5:35 am-11:29 am

1 stop5h 54m

$249

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 12/10

6:03 pm-10:29 pm

1 stop4h 26m

Des Moines

Sun 12/14

8:15 am-1:14 pm

1 stop4h 59m

$249

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

Wed 2/18

6:00 am-11:43 am

1 stop5h 43m

Cedar Rapids

Sat 2/21

12:25 pm-11:19 pm

2 stops10h 54m

$249

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Tue 12/16

3:08 pm-11:35 pm

1 stop8h 27m

Des Moines

Fri 1/2

2:07 pm-7:57 pm

1 stop5h 50m

$249

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Tue 12/9

10:32 am-5:47 pm

1 stop7h 15m

Des Moines

Sun 12/14

2:16 pm-9:53 pm

1 stop7h 37m

$249

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 12/10

6:07 am-1:31 pm

1 stop7h 24m

Des Moines

Sun 12/14

2:16 pm-9:53 pm

1 stop7h 37m

$249

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 12/10

7:20 am-4:25 pm

2 stops9h 05m

Des Moines

Sun 12/14

5:25 pm-10:32 pm

1 stop5h 07m

$254

GulfportOmaha

GPT - OMA

GPTOMA

Gulfport Biloxi Regional

Tue 11/25

6:03 pm-12:14 am

1 stop6h 11m

Omaha Eppley Airfield

Thu 11/27

4:00 pm-10:07 pm

1 stop6h 07m

$264

Baton RougeMoline

BTR - MLI

BTRMLI

Baton Rouge Ryan

Wed 4/15

3:20 pm-10:31 pm

1 stop7h 11m

Moline Quad-City

Sat 4/18

5:55 am-12:47 pm

1 stop6h 52m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 56 results
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Best time to book a flight from Mississippi to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Iowa

What is the cheapest time of day to fly from MS to IA?

Find hourly flight availability from Mississippi to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

When flying from Mississippi to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 38% versus a flight at noon.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated November 13, 2025.
Read through reviews of airlines operating flights from Mississippi to Iowa, such as Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Crew

8.5

Overall

7.9

Food

7.3

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Overall

7.9

Food

7.3

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Iowa?

    For as low as $249, American Airlines can have you in Iowa from Mississippi in 4h 26m. Airlines will cover a distance of 773 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Iowa one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $69. However, be on the lookout for offers from Allegiant Air and Delta, as they are both options that can get you from Mississippi to Iowa for a low price.

  • Can I find deals for flights from Mississippi to Iowa that include hotel bookings?

    Yes. In addition to deals on Mississippi to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Iowa.

  • Can I find deals for business class flights from Mississippi to Iowa?

    Yes. Cheapflights offers flight deals from Mississippi to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to Iowa

Discover the top airline that operate flights from Mississippi to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$124Average$254FlexibilityNo cancel feeOn-timeN/A

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