Iowa

$279+ Cheap flights from Mississippi to Iowa

JAN — DSM
Nov 29 — Dec 61
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to Iowa

Cheapest flights from Mississippi to Iowa

Thu 11/195:06 pm -
1 stop6h 03m
Mon 11/305:15 am -
1 stop5h 14m
Deal found 10/27$359
Fri 12/184:55 pm -
1 stop5h 34m
Thu 12/245:00 am -
2 stops11h 05m
Deal found 10/28$410
Sat 12/51:55 pm -
2 stops9h 20m
Wed 12/98:00 am -
1 stop5h 20m
Deal found 10/29$444
Wed 11/115:06 pm -
1 stop5h 29m
Sun 11/155:30 am -
1 stop7h 10m
Deal found 10/27$517
Mon 11/165:32 pm -
1 stop5h 54m
Thu 11/193:25 pm -
1 stop7h 50m
Deal found 10/26$519
Fri 11/131:57 pm -
2 stops9h 45m
Tue 11/178:00 am -
1 stop5h 19m
Deal found 10/28$522
Fri 11/135:40 am -
2 stops10h 10m
Tue 11/177:00 am -
2 stops10h 35m
Deal found 10/28$527
Wed 11/116:30 am -
2 stops7h 45m
Sun 11/155:25 am -
2 stops14h 20m
Deal found 10/27$533
Mon 11/164:55 pm -
1 stop5h 35m
Wed 11/186:05 am -
2 stops10h 03m
Deal found 10/25$578
Wed 11/1112:21 pm -
2 stops10h 44m
Sun 11/157:06 am -
1 stop7h 14m
Deal found 10/27$599
Wed 11/111:57 pm -
2 stops9h 02m
Sun 11/158:00 am -
1 stop5h 19m
Deal found 10/27$706
Thu 11/195:00 am -
2 stops8h 33m
Mon 11/301:10 pm -
1 stop8h 43m
Deal found 10/30$782

Find flight deals from Mississippi to Iowa

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Delta)

One-way from

$279
(American Airlines)
Provider with most accurate pricing for Jackson-Evers Intl-Des Moines flight deals.
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Des Moines flights.
From Mississippi to Iowa
One-way flight from Mississippi to Iowa

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Mississippi to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportDes Moines

GPT Gulfport Biloxi Regional - DSM Des Moines

GPTDSM

Gulfport Biloxi Regional

Sun 11/15

7:45 pm-7:35 pm

2 stops23h 50m

Des Moines

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$341

JacksonCedar Rapids

JAN Jackson-Evers Intl - CID Cedar Rapids

JANCID

Jackson-Evers Intl

Thu 11/19

5:06 pm-11:09 pm

1 stop6h 03m

Cedar Rapids

Mon 11/30

5:15 am-10:29 am

1 stop5h 14m

$359
Quickest round-trip

JacksonCedar Rapids

JAN Jackson-Evers Intl - CID Cedar Rapids

JANCID

Jackson-Evers Intl

Thu 11/12

5:06 pm-11:09 pm

1 stop6h 03m

Cedar Rapids

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$389

GulfportDes Moines

GPT Gulfport Biloxi Regional - DSM Des Moines

GPTDSM

Gulfport Biloxi Regional

Fri 12/18

4:55 pm-10:29 pm

1 stop5h 34m

Des Moines

Thu 12/24

5:00 am-4:05 pm

2 stops11h 05m

$410

GulfportDes Moines

GPT Gulfport Biloxi Regional - DSM Des Moines

GPTDSM

Gulfport Biloxi Regional

Mon 11/16

4:55 pm-10:59 pm

2 stops30h 04m

Des Moines

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$428

GulfportDes Moines

GPT Gulfport Biloxi Regional - DSM Des Moines

GPTDSM

Gulfport Biloxi Regional

Sat 12/5

1:55 pm-11:15 pm

2 stops9h 20m

Des Moines

Wed 12/9

8:00 am-1:20 pm

1 stop5h 20m

$444

JacksonDes Moines

JAN Jackson-Evers Intl - DSM Des Moines

JANDSM

Jackson-Evers Intl

Wed 11/11

5:06 pm-10:35 pm

1 stop5h 29m

Des Moines

Sun 11/15

5:30 am-12:40 pm

1 stop7h 10m

$517

JacksonDes Moines

JAN Jackson-Evers Intl - DSM Des Moines

JANDSM

Jackson-Evers Intl

Sat 11/14

9:05 am-2:20 pm

1 stop5h 15m

Des Moines

Wed 11/18

3:01 pm-8:26 pm

1 stop5h 25m

$517

JacksonDes Moines

JAN Jackson-Evers Intl - DSM Des Moines

JANDSM

Jackson-Evers Intl

Fri 11/13

5:06 pm-10:35 pm

1 stop5h 29m

Des Moines

Tue 11/17

6:52 pm-11:05 pm

1 stop4h 13m

$517

JacksonDes Moines

JAN Jackson-Evers Intl - DSM Des Moines

JANDSM

Jackson-Evers Intl

Fri 11/13

1:57 pm-11:42 pm

2 stops9h 45m

Des Moines

Tue 11/17

8:00 am-1:19 pm

1 stop5h 19m

$522

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Mississippi to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Mississippi with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Iowa

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Iowa

Read through reviews of airlines operating flights from Mississippi to Iowa, such as American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

7.9

Overall

7.0

Comfort

7.2

Entertainment

6.8

Boarding

7.4

Food

6.4

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Crew

7.9

Overall

7.0

Comfort

7.2

Entertainment

6.8

Boarding

7.4

Food

6.4

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

  • How long is the flight from Mississippi to Iowa?

    For as low as $410, Delta can have you in Iowa from Mississippi in 5h 34m. Airlines will cover a distance of 810 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mississippi to Iowa that include hotel bookings?

    Yes. In addition to deals on Mississippi to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Iowa.

  • Can I find deals for business class flights from Mississippi to Iowa?

    Yes. Cheapflights offers flight deals from Mississippi to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Mississippi to Iowa

Top airline flying from Mississippi to Iowa

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$326Average$326FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.