HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$87+ Cheap flights from Mississippi to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — DSM
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to Iowa

Cheapest flights from Mississippi to Iowa
Explore the most affordable flight options available from Mississippi to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:11 amBTR - OMA
1 stop7h 28mAmerican Airlines
Tue 12/305:04 amOMA - BTR
1 stop4h 35mAmerican Airlines
Deal found 12/6$309
This Delta deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:39 amBTR - DSM
1 stop5h 52mDelta
Mon 1/195:16 pmDSM - BTR
1 stop4h 45mDelta
Deal found 12/8$309
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:00 amBTR - DSM
2 stops9h 19mAmerican Airlines
Sun 1/1811:42 amDSM - BTR
2 stops9h 17mAmerican Airlines
Deal found 12/8$319
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:48 pmMEM - MLI
1 stop6h 33mUnited Airlines
Fri 12/2610:47 amMLI - MEM
1 stop4h 01mUnited Airlines
Deal found 12/7$331
This Delta deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:59 pmBTR - OMA
1 stop5h 17mDelta
Sun 12/147:00 amOMA - BTR
1 stop6h 36mDelta
Deal found 12/7$354
This Delta deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:59 pmBTR - OMA
1 stop5h 18mDelta
Sun 12/2111:41 amOMA - BTR
1 stop6h 37mDelta
Deal found 12/7$369
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:32 amBTR - DSM
1 stop5h 17mAmerican Airlines
Thu 1/15:39 pmDSM - BTR
1 stop4h 58mAmerican Airlines
Deal found 12/6$373
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:35 amBTR - OMA
2 stops12h 23mUnited Airlines
Mon 12/295:45 amOMA - BTR
2 stops10h 02mUnited Airlines
Deal found 12/8$374
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:11 amBTR - OMA
1 stop7h 28mAmerican Airlines
Mon 12/295:04 amOMA - BTR
1 stop4h 35mAmerican Airlines
Deal found 12/8$384
This Delta deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:59 pmBTR - OMA
1 stop5h 09mDelta
Fri 1/211:41 amOMA - BTR
1 stop6h 37mDelta
Deal found 12/6$389
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:53 pmBTR - OMA
1 stop5h 06mAmerican Airlines
Sat 12/275:04 amOMA - BTR
1 stop4h 35mAmerican Airlines
Deal found 12/6$399
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:11 pmBTR - OMA
1 stop7h 08mUnited Airlines
Sun 12/216:10 amOMA - BTR
1 stop6h 57mUnited Airlines
Deal found 12/6$407

Find flight deals from Mississippi to Iowa

Keep the following information in mind while searching for Mississippi to Iowa flight deals. Data was last updated December 8, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(United Airlines)

One-way from

$87
(Trip.com)
Provider with most accurate pricing for Jackson-Evers Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Des Moines flights.
Search Deals
From Mississippi to Iowa
Search Deals
One-way flight from Mississippi to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Mississippi to Iowa that are best for you.

Fly from

Mississippi

Fly to

Iowa

Route

Depart

Return

Price

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 1/7

9:30 am-2:22 pm

1 stop4h 52m

Des Moines

Wed 1/14

3:04 pm-9:32 pm

1 stop6h 28m

$249

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Wed 1/7

5:51 pm-10:29 pm

1 stop4h 38m

Des Moines

Wed 1/14

12:04 pm-10:01 pm

2 stops9h 57m

$254

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 2/14

6:00 am-12:14 pm

1 stop6h 14m

Des Moines

Mon 2/16

4:21 pm-10:24 pm

1 stop6h 03m

$278

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sun 2/15

7:00 am-1:17 pm

1 stop6h 17m

Des Moines

Tue 2/17

6:38 pm-10:48 pm

1 stop4h 10m

$289

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 2/17

6:00 am-10:17 am

1 stop4h 17m

Des Moines

Sun 2/22

6:50 am-11:41 am

1 stop4h 51m

$289

MemphisCedar Rapids

MEM - CID

MEMCID

Memphis

Fri 1/9

9:55 am-4:52 pm

1 stop6h 57m

Cedar Rapids

Mon 1/12

3:10 pm-9:59 pm

1 stop6h 49m

$304

Baton RougeOmaha

BTR - OMA

BTROMA

Baton Rouge Ryan

Thu 12/25

7:11 am-2:39 pm

1 stop7h 28m

Omaha Eppley Airfield

Tue 12/30

5:04 am-9:39 am

1 stop4h 35m

$309

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 1/5

6:10 am-11:24 am

1 stop5h 14m

Des Moines

Mon 1/12

5:16 pm-9:51 pm

1 stop4h 35m

$318

Baton RougeOmaha

BTR - OMA

BTROMA

Baton Rouge Ryan

Sat 1/31

1:55 pm-6:54 pm

1 stop4h 59m

Omaha Eppley Airfield

Wed 2/4

3:00 pm-9:32 pm

1 stop6h 32m

$319

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 1/5

7:05 am-2:53 pm

2 stops7h 48m

Des Moines

Mon 1/12

5:51 pm-10:51 pm

1 stop5h 00m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Mississippi to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Iowa

What is the cheapest time of day to fly from MS to IA?

Find hourly flight availability from Mississippi to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

When flying from Mississippi to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 38% versus a flight at noon.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated December 8, 2025.
Read through reviews of airlines operating flights from Mississippi to Iowa, such as Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Iowa?

    For as low as $254, United Airlines can have you in Iowa from Mississippi in 4h 38m. Airlines will cover a distance of 773 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mississippi to Iowa that include hotel bookings?

    Yes. In addition to deals on Mississippi to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Iowa.

  • Can I find deals for business class flights from Mississippi to Iowa?

    Yes. Cheapflights offers flight deals from Mississippi to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Miami flights
Los Angeles to John F Kennedy Intl flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to Los Angeles flights
Newark to Miami flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Orlando flights
Los Angeles to Newark flights
Newark to West Palm Beach flights
John F Kennedy Intl to Dallas/Fort Worth flights
Dallas/Fort Worth to LaGuardia flights
John F Kennedy Intl to West Palm Beach flights
Newark to Las Vegas flights
Dallas/Fort Worth to Newark flights
Newark to Los Angeles flights
Seattle to Los Angeles flights
LaGuardia to Dallas/Fort Worth flights
Dallas/Fort Worth to Las Vegas flights
Atlanta to John F Kennedy Intl flights
O'Hare Intl to John F Kennedy Intl flights
Newark to Dallas/Fort Worth flights
O'Hare Intl to Dallas/Fort Worth flights
Newark to Orlando flights
San Francisco to John F Kennedy Intl flights
Atlanta to LaGuardia flights
Seattle to Las Vegas flights
O'Hare Intl to Las Vegas flights
John F Kennedy Intl to Atlanta flights
John F Kennedy Intl to Tampa flights
Dulles Intl to Miami flights
San Francisco to Las Vegas flights
Dallas/Fort Worth to Los Angeles flights
John F Kennedy Intl to San Francisco flights
Los Angeles to LaGuardia flights
Los Angeles to San Francisco flights
Los Angeles to Dallas/Fort Worth flights
Fort Lauderdale to John F Kennedy Intl flights
Dulles Intl to Dallas/Fort Worth flights
Seattle to Sky Harbor Intl flights
Dallas/Fort Worth to Seattle flights
Los Angeles to Seattle flights
Reagan-National to Miami flights
LaGuardia to Orlando flights
LaGuardia to Tampa flights
San Francisco to Newark flights
Minneapolis to Sky Harbor Intl flights

Top airline flying from Mississippi to Iowa

Discover the top airline that operate flights from Mississippi to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$124Average$254FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.