$121+ Cheap flights from Iowa to Mississippi
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAN
Jun 15 — Jun 221
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Mississippi
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Cheapest flights from Iowa to MississippiExplore the most affordable flight options available from Iowa to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 16, 2026.
Explore the most affordable flight options available from Iowa to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 16, 2026.
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:15 pm
OMA
- MOB
1 stop4h 51m
Delta
Wed 8/196:00 am
MOB
- OMA
1 stop7h 37m
Delta
Deal found 5/16![Delta logo]()
$261
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:40 pm
OMA
- MEM
1 stop4h 41m
United Airlines
Tue 6/167:25 am
MEM
- OMA
1 stop6h 52m
United Airlines
Deal found 5/12![United Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:42 am
DSM
- MEM
1 stop6h 36m
Delta
Tue 7/75:57 pm
MEM
- DSM
1 stop4h 32m
Delta
Deal found 5/16![Delta logo]()
$281
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:15 pm
OMA
- MOB
1 stop4h 51m
Delta
Fri 8/1412:06 pm
MOB
- OMA
1 stop5h 14m
Delta
Deal found 5/16![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:20 am
DSM
- MEM
2 stops9h 40m
Southwest
Tue 7/75:20 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 5/16![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:56 am
MLI
- MEM
1 stop5h 43m
Delta
Sun 6/75:54 pm
MEM
- MLI
1 stop4h 40m
Delta
Deal found 5/13![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:17 pm
MLI
- MEM
1 stop5h 59m
Delta
Mon 6/19:30 am
MEM
- MLI
1 stop7h 07m
Delta
Deal found 5/13![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
MLI
- MEM
2 stops8h 07m
American Airlines
Sun 6/75:53 am
MEM
- MLI
1 stop4h 46m
American Airlines
Deal found 5/13![American Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
MLI
- MEM
2 stops8h 07m
American Airlines
Mon 6/12:56 pm
MEM
- MLI
1 stop7h 06m
American Airlines
Deal found 5/13![American Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:40 pm
DSM
- MEM
1 stop6h 25m
Southwest
Wed 6/175:20 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 5/13![Southwest logo]()
$296
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:15 pm
OMA
- MEM
1 stop6h 38m
United Airlines
Thu 10/157:30 am
MEM
- OMA
1 stop6h 56m
United Airlines
Deal found 5/13![United Airlines logo]()
$297
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:19 pm
OMA
- MEM
1 stop22h 50m
Frontier
Mon 6/17:54 pm
MEM
- OMA
1 stop23h 30m
Frontier
Deal found 5/13![Frontier logo]()
$305
Best flights from Iowa to MississippiDiscover carefully curated flight deals from Iowa to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 16, 2026.
Discover carefully curated flight deals from Iowa to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 16, 2026.
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:42 am
DSM
- MEM
1 stop6h 36m
Delta
Tue 7/75:57 pm
MEM
- DSM
1 stop4h 32m
Delta
Deal found 5/16![Delta logo]()
$281
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
MLI
- MEM
2 stops8h 07m
American Airlines
Sun 6/75:53 am
MEM
- MLI
1 stop4h 46m
American Airlines
Deal found 5/13![American Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:40 pm
DSM
- MEM
1 stop6h 25m
Southwest
Wed 6/175:20 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 5/13![Southwest logo]()
$296
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/193:44 pm
MLI
- MEM
1 stop6h 13m
United Airlines
Wed 9/235:45 am
MEM
- MLI
1 stop7h 13m
United Airlines
Deal found 5/13![United Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:56 am
MLI
- MEM
1 stop5h 43m
Delta
Sun 6/75:54 pm
MEM
- MLI
1 stop4h 40m
Delta
Deal found 5/13![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:02 pm
CID
- GPT
1 stop5h 03m
American Airlines
Wed 10/76:27 pm
GPT
- CID
1 stop5h 12m
American Airlines
Deal found 5/15![American Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:20 am
DSM
- MEM
2 stops9h 40m
Southwest
Sat 6/203:15 pm
MEM
- DSM
1 stop7h 35m
Southwest
Deal found 5/12![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:20 am
DSM
- BTR
1 stop5h 00m
United Airlines
Mon 8/36:09 pm
BTR
- DSM
1 stop4h 26m
United Airlines
Deal found 5/15![United Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:56 am
MLI
- MEM
1 stop5h 43m
Delta
Sat 5/304:11 pm
MEM
- MLI
1 stop6h 10m
Delta
Deal found 5/11![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:56 pm
MLI
- MEM
1 stop3h 59m
American Airlines
Sat 5/302:56 pm
MEM
- MLI
2 stops8h 59m
American Airlines
Deal found 5/11![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:30 am
OMA
- MEM
2 stops8h 05m
Southwest
Thu 10/155:00 am
MEM
- OMA
1 stop6h 25m
Southwest
Deal found 5/13![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:02 pm
DSM
- MEM
1 stop6h 54m
United Airlines
Wed 8/196:15 am
MEM
- DSM
1 stop4h 11m
United Airlines
Deal found 5/13![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 pm
DSM
- MOB
1 stop4h 27m
Delta
Tue 11/176:00 am
MOB
- DSM
1 stop4h 18m
Delta
Deal found 5/15![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:10 am
DSM
- MEM
1 stop6h 30m
Southwest
Tue 6/165:20 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 5/14![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:04 pm
OMA
- GPT
1 stop6h 55m
American Airlines
Sat 7/47:04 am
GPT
- OMA
1 stop5h 30m
American Airlines
Deal found 5/14![American Airlines logo]()
$346
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:40 pm
OMA
- MEM
1 stop4h 41m
United Airlines
Wed 6/247:25 am
MEM
- OMA
1 stop6h 52m
United Airlines
Deal found 5/15![United Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:33 pm
OMA
- MEM
1 stop4h 53m
Delta
Sun 6/217:10 pm
MEM
- OMA
1 stop4h 40m
Delta
Deal found 5/15![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:20 am
DSM
- MEM
2 stops9h 40m
Southwest
Sat 6/275:00 am
MEM
- DSM
2 stops9h 50m
Southwest
Deal found 5/15![Southwest logo]()
$344
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:30 am
DSM
- BTR
1 stop5h 30m
American Airlines
Wed 6/176:28 pm
BTR
- DSM
1 stop5h 44m
American Airlines
Deal found 5/14![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:04 pm
OMA
- MOB
1 stop6h 25m
United Airlines
Tue 9/2911:35 am
MOB
- OMA
2 stops11h 24m
United Airlines
Deal found 5/15![United Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:46 am
OMA
- MOB
1 stop6h 12m
Delta
Tue 7/146:55 pm
MOB
- OMA
1 stop4h 53m
Delta
Deal found 5/12![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:10 pm
OMA
- BTR
1 stop5h 49m
American Airlines
Wed 6/36:28 pm
BTR
- OMA
1 stop5h 54m
American Airlines
Deal found 5/11![American Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:40 pm
DSM
- MEM
1 stop6h 25m
Southwest
Thu 6/1812:15 pm
MEM
- DSM
2 stops11h 15m
Southwest
Deal found 5/13![Southwest logo]()
$384
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
DSM
- BTR
1 stop7h 02m
United Airlines
Tue 9/14:10 pm
BTR
- DSM
1 stop6h 20m
United Airlines
Deal found 5/15![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:17 am
OMA
- BTR
1 stop5h 28m
American Airlines
Mon 6/156:28 pm
BTR
- OMA
1 stop5h 53m
American Airlines
Deal found 5/11![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:35 pm
DSM
- JAN
1 stop4h 36m
Delta
Sun 8/161:00 pm
JAN
- DSM
1 stop4h 48m
Delta
Deal found 5/14![Delta logo]()
$362
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:59 pm
OMA
- BTR
1 stop6h 29m
United Airlines
Tue 9/14:10 pm
BTR
- OMA
1 stop6h 00m
United Airlines
Deal found 5/14![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:05 pm
OMA
- MEM
2 stops6h 50m
Southwest
Mon 7/272:30 pm
MEM
- OMA
1 stop6h 50m
Southwest
Deal found 5/12![Southwest logo]()
$392
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 pm
DSM
- JAN
1 stop4h 53m
Delta
Sun 11/87:45 am
JAN
- DSM
1 stop5h 42m
Delta
Deal found 5/13![Delta logo]()
$362
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/71:41 pm
DSM
- BTR
1 stop7h 49m
American Airlines
Mon 8/36:28 pm
BTR
- DSM
1 stop5h 41m
American Airlines
Deal found 5/11![American Airlines logo]()
$393
Last-minute flights from Iowa to MississippiDiscover last-minute flight deals from Iowa to Mississippi. Data last updated May 16, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Mississippi. Data last updated May 16, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:17 pm
MLI
- MEM
1 stop5h 59m
Delta
Mon 6/19:30 am
MEM
- MLI
1 stop7h 07m
Delta
Deal found 5/13![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
MLI
- MEM
2 stops8h 07m
American Airlines
Mon 6/12:56 pm
MEM
- MLI
1 stop7h 06m
American Airlines
Deal found 5/13![American Airlines logo]()
$295
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:19 pm
OMA
- MEM
1 stop22h 50m
Frontier
Mon 6/17:54 pm
MEM
- OMA
1 stop23h 30m
Frontier
Deal found 5/13![Frontier logo]()
$305
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:56 am
MLI
- MEM
1 stop5h 43m
Delta
Sun 6/75:54 pm
MEM
- MLI
1 stop4h 40m
Delta
Deal found 5/13![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
MLI
- MEM
2 stops8h 07m
American Airlines
Sun 6/75:53 am
MEM
- MLI
1 stop4h 46m
American Airlines
Deal found 5/13![American Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:40 pm
OMA
- MEM
1 stop4h 41m
United Airlines
Tue 6/167:25 am
MEM
- OMA
1 stop6h 52m
United Airlines
Deal found 5/12![United Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:40 pm
DSM
- MEM
1 stop6h 25m
Southwest
Wed 6/175:20 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 5/13![Southwest logo]()
$296
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:05 pm
DSM
- MEM
1 stop4h 17m
American Airlines
Thu 6/186:07 am
MEM
- DSM
1 stop6h 56m
American Airlines
Deal found 5/13![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:39 pm
DSM
- MEM
1 stop4h 47m
Delta
Sat 6/276:00 am
MEM
- DSM
1 stop4h 14m
Delta
Deal found 5/15![Delta logo]()
$314
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:42 am
DSM
- MEM
1 stop6h 36m
Delta
Tue 7/75:57 pm
MEM
- DSM
1 stop4h 32m
Delta
Deal found 5/16![Delta logo]()
$281
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:20 am
DSM
- MEM
2 stops9h 40m
Southwest
Tue 7/75:20 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 5/16![Southwest logo]()
$286
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:04 pm
OMA
- GPT
1 stop6h 55m
American Airlines
Sat 7/410:36 am
GPT
- OMA
2 stops8h 27m
American Airlines
Deal found 5/14![American Airlines logo]()
$309
One-way flights from Iowa to MississippiSearch for one-way flight options from Iowa to Mississippi. Find affordable one-way fares based on user searches. Data last updated May 16, 2026.
Search for one-way flight options from Iowa to Mississippi. Find affordable one-way fares based on user searches. Data last updated May 16, 2026.
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:41 pm
OMA
- MEM
1 stop17h 41m
Frontier
Deal found 5/14![Frontier logo]()
$121
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:01 pm
DSM
- MEM
1 stop7h 05m
United Airlines
Deal found 5/12![United Airlines logo]()
$141
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:20 am
DSM
- MEM
2 stops9h 40m
Southwest
Deal found 5/12![Southwest logo]()
$146
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/78:19 pm
OMA
- MEM
1 stop22h 50m
Frontier
Deal found 5/11![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:35 pm
CID
- GPT
1 stop12h 06m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$167
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:10 am
OMA
- MEM
2 stops10h 55m
Southwest
Deal found 5/14![Southwest logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:04 pm
CID
- GPT
1 stop25h 06m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$175
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/184:40 pm
DSM
- MEM
1 stop6h 40m
Southwest
Deal found 5/15![Southwest logo]()
$184
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:19 pm
OMA
- MEM
1 stop22h 50m
Frontier
Deal found 5/13![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:16 pm
DSM
- MEM
1 stop14h 16m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$193
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:46 am
OMA
- MEM
1 stop4h 51m
Delta
Deal found 5/16![Delta logo]()
$194
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:15 am
OMA
- MEM
2 stops7h 35m
Southwest
Deal found 5/16![Southwest logo]()
$199
Find flight deals from Iowa to Mississippi
Keep the following information in mind while searching for Iowa to Mississippi flight deals. Data was last updated May 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (Delta) |
One-way from | $121 (Booking.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 16, 2026.
Use the filters below to find and compare flights from Iowa to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Tue 6/30
11:42 am-6:18 pm
1 stop6h 36m
Memphis
Tue 7/7
5:57 pm-10:29 pm
1 stop4h 32m
$281
MolineMemphis
MLI - MEM
MLIMEM
Moline Quad-City
Wed 6/3
5:56 am-11:39 am
1 stop5h 43m
Memphis
Sun 6/7
5:54 pm-10:34 pm
1 stop4h 40m
$289
MolineMemphis
MLI - MEM
MLIMEM
Moline Quad-City
Wed 6/3
6:00 am-2:07 pm
2 stops8h 07m
Memphis
Sun 6/7
5:53 am-10:39 am
1 stop4h 46m
$294
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Thu 6/11
4:40 pm-11:05 pm
1 stop6h 25m
Memphis
Wed 6/17
5:20 am-11:30 am
1 stop6h 10m
$296
Cedar RapidsGulfport
CID - GPT
CIDGPT
Cedar Rapids
Sat 10/3
6:02 pm-11:05 pm
1 stop5h 03m
Gulfport Biloxi Regional
Wed 10/7
6:27 pm-11:39 pm
1 stop5h 12m
$311
MolineMemphis
MLI - MEM
MLIMEM
Moline Quad-City
Tue 5/26
5:56 am-11:39 am
1 stop5h 43m
Memphis
Sat 5/30
4:11 pm-10:21 pm
1 stop6h 10m
$319
Quickest round-trip
Des MoinesMobile
DSM - MOB
DSMMOB
Des Moines
Tue 11/10
6:30 pm-10:57 pm
1 stop4h 27m
Mobile
Tue 11/17
6:00 am-10:18 am
1 stop4h 18m
$323
MolineMemphis
MLI - MEM
MLIMEM
Moline Quad-City
Tue 5/26
6:56 pm-10:55 pm
1 stop3h 59m
Memphis
Sat 5/30
2:56 pm-11:55 pm
2 stops8h 59m
$324
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Tue 6/16
5:20 am-3:00 pm
2 stops9h 40m
Memphis
Sat 6/20
3:15 pm-10:50 pm
1 stop7h 35m
$325
OmahaMemphis
OMA - MEM
OMAMEM
Omaha Eppley Airfield
Tue 10/13
5:30 am-1:35 pm
2 stops8h 05m
Memphis
Thu 10/15
5:00 am-11:25 am
1 stop6h 25m
$326
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Iowa with our price prediction graph.
OMA-MOB
OMA-MEM
DSM-MEM
MLI-MEM
OMA-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Mississippi
USIA-USMS
OMA-MOB
OMA-MEM
DSM-MEM
MLI-MEM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated May 16, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Iowa to Mississippi by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.6
Crew
8.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Overall
7.4
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.6
Crew
8.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Overall
7.4
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.6
Crew
8.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Iowa to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Mississippi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Mississippi by cabin class
Find flights from Iowa to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Mississippi flights
Browse other Iowa and Mississippi flight options. Last updated on May 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mississippi
Find the right flight back to Iowa after your stay in Mississippi
Iowa to Mississippi flights
Consider these flights traveling from Iowa to Mississippi.
Top 2 airlines flying from Iowa to Mississippi
Discover the top 2 airlines that operate flights from Iowa to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$452 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$318 | Average$381 | FlexibilityNo cancel fee | On-time69% |