$95+ Cheap flights from South Carolina to Indianapolis (IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to IndianapolisExplore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:13 pm -
1 stop20h 12m
Tue 10/611:21 am -
1 stop21h 17m
Deal found 9/11![Multiple Airlines logo]()
$194
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:05 pm -
1 stop7h 55m
Wed 10/219:06 pm -
1 stop11h 31m
Deal found 9/11![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:38 pm -
1 stop18h 37m
Fri 10/231:10 pm -
1 stop6h 45m
Deal found 9/10![Frontier logo]()
$218
This CheapOair deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:40 pm -
1 stop11h 51m
Tue 10/611:21 am -
1 stop21h 14m
Deal found 9/11![Frontier logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:27 pm -
1 stop18h 58m
Mon 10/59:20 pm -
1 stop11h 18m
Deal found 9/9![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am -
2 stops35h 57m
Mon 11/26:00 am -
1 stop26h 38m
Deal found 9/11![Multiple Airlines logo]()
$226
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:05 pm -
1 stop9h 22m
Wed 10/219:06 pm -
1 stop11h 31m
Deal found 9/14![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:07 pm -
1 stop12h 11m
Wed 10/77:48 pm -
2 stops48h 04m
Deal found 9/9![Multiple Airlines logo]()
$233
This Orbitz deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:32 am -
1 stop24h 58m
Sun 11/1511:25 am -
1 stop21h 12m
Deal found 9/10![Frontier logo]()
$235
This Super.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:05 pm -
1 stop7h 55m
Tue 10/2011:21 am -
1 stop27h 53m
Deal found 9/13![Frontier logo]()
$236
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:38 pm -
1 stop18h 15m
Tue 11/311:25 am -
1 stop21h 12m
Deal found 9/14![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:49 pm -
1 stop21h 54m
Sat 11/71:47 pm -
2 stops19h 45m
Deal found 9/10![Multiple Airlines logo]()
$245
Best flights from South Carolina to IndianapolisDiscover carefully curated flight deals from South Carolina to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from South Carolina to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop5h 50m
Sat 12/122:25 pm -
1 stop4h 05m
Deal found 9/14![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:23 pm -
1 stop7h 21m
Mon 10/124:55 pm -
1 stop4h 53m
Deal found 9/9![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
1 stop4h 56m
Tue 11/177:05 am -
1 stop4h 03m
Deal found 9/13![Delta logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:46 pm -
1 stop19h 44m
Sun 11/87:35 am -
2 stops24h 28m
Deal found 9/11![Multiple Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:33 pm -
1 stop6h 04m
Wed 10/218:00 am -
1 stop6h 23m
Deal found 9/11![American Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:05 pm -
1 stop5h 13m
Mon 11/308:08 pm -
1 stop3h 45m
Deal found 9/10![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:10 am -
2 stops8h 35m
Thu 11/55:30 am -
1 stop4h 35m
Deal found 9/14![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:56 pm -
1 stop6h 51m
Sun 11/84:30 pm -
1 stop4h 53m
Deal found 9/10![United Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:02 pm -
1 stop18h 23m
Sat 10/37:48 pm -
2 stops36h 15m
Deal found 9/14![Multiple Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:19 pm -
1 stop5h 06m
Tue 12/12:06 pm -
1 stop6h 06m
Deal found 9/12![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:40 am -
2 stops11h 30m
Sun 11/155:30 pm -
2 stops5h 30m
Deal found 9/14![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:35 pm -
2 stops9h 35m
Mon 10/56:45 am -
2 stops9h 25m
Deal found 9/9![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 am -
1 stop4h 26m
Sun 10/184:55 pm -
1 stop4h 38m
Deal found 9/11![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:45 am -
1 stop6h 30m
Sun 10/43:39 pm -
1 stop5h 58m
Deal found 9/12![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:40 am -
1 stop3h 36m
Tue 10/136:00 am -
1 stop3h 23m
Deal found 9/13![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:40 pm -
2 stops10h 40m
Sun 11/85:30 am -
1 stop4h 35m
Deal found 9/14![Southwest logo]()
$350
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:16 am -
2 stops7h 36m
Tue 11/176:22 am -
2 stops7h 55m
Deal found 9/13![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:25 pm -
1 stop5h 00m
Tue 10/205:25 pm -
1 stop6h 30m
Deal found 9/13![Delta logo]()
$387
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:30 am -
2 stops11h 05m
Mon 12/145:25 pm -
1 stop3h 35m
Deal found 9/10![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:20 am -
1 stop6h 24m
Sun 11/86:00 am -
2 stops8h 16m
Deal found 9/10![United Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:23 am -
1 stop6h 04m
Wed 9/308:06 am -
1 stop3h 14m
Deal found 9/11![American Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:45 am -
2 stops8h 00m
Tue 12/295:30 am -
1 stop4h 30m
Deal found 9/10![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 pm -
1 stop4h 29m
Sun 11/17:10 am -
2 stops7h 35m
Deal found 9/11![United Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:09 pm -
1 stop4h 16m
Wed 10/1410:21 am -
1 stop5h 20m
Deal found 9/13![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:30 am -
2 stops9h 35m
Tue 10/2012:35 pm -
2 stops8h 30m
Deal found 9/13![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:00 am -
1 stop5h 03m
Mon 10/127:58 pm -
1 stop4h 01m
Deal found 9/10![American Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:27 am -
2 stops7h 55m
Wed 11/116:00 am -
2 stops11h 11m
Deal found 9/10![United Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:02 pm -
1 stop5h 22m
Mon 10/126:00 am -
1 stop3h 19m
Deal found 9/14![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:40 pm -
2 stops10h 35m
Mon 12/215:10 am -
2 stops9h 10m
Deal found 9/14![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:23 am -
2 stops7h 29m
Mon 11/2312:46 pm -
2 stops11h 13m
Deal found 9/10![United Airlines logo]()
$443
Last-minute flights from South Carolina to IndianapolisDiscover last-minute flight deals from South Carolina to Indianapolis. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indianapolis. Data last updated September 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:13 pm -
1 stop20h 12m
Tue 10/611:21 am -
1 stop21h 17m
Deal found 9/11![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:07 pm -
1 stop12h 11m
Wed 10/77:48 pm -
2 stops48h 04m
Deal found 9/9![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:13 pm -
1 stop20h 12m
Mon 10/57:48 pm -
2 stops36h 50m
Deal found 9/11![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:27 pm -
1 stop18h 58m
Mon 10/59:20 pm -
1 stop11h 18m
Deal found 9/9![Multiple Airlines logo]()
$223
This CheapOair deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:40 pm -
1 stop11h 51m
Tue 10/611:21 am -
1 stop21h 14m
Deal found 9/11![Frontier logo]()
$220
This CheapOair deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:40 pm -
1 stop12h 46m
Wed 10/1410:22 pm -
1 stop12h 43m
Deal found 9/12![Frontier logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:38 pm -
1 stop18h 37m
Fri 10/231:10 pm -
1 stop6h 45m
Deal found 9/10![Frontier logo]()
$218
This Super.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:05 pm -
1 stop7h 55m
Tue 10/2011:21 am -
1 stop27h 53m
Deal found 9/13![Frontier logo]()
$236
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:05 pm -
1 stop9h 22m
Wed 10/219:06 pm -
1 stop11h 31m
Deal found 9/14![Frontier logo]()
$230
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:05 pm -
1 stop7h 55m
Wed 10/219:06 pm -
1 stop11h 31m
Deal found 9/11![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am -
2 stops35h 57m
Mon 11/26:00 am -
1 stop26h 38m
Deal found 9/11![Multiple Airlines logo]()
$226
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:38 pm -
1 stop18h 15m
Tue 11/311:25 am -
1 stop21h 12m
Deal found 9/14![Frontier logo]()
$245
One-way flights from South Carolina to IndianapolisSearch for one-way flight options from South Carolina to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from South Carolina to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:32 am -
2 stops33h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am -
2 stops12h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:00 pm -
2 stops28h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$103
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:05 pm -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops12h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:00 pm -
1 stop19h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$108
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:15 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$111
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:47 pm -
1 stop19h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$111
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:52 pm -
1 stop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$117
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:05 pm -
1 stop9h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$121
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:40 pm -
1 stop12h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:12 pm -
2 stops24h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$125
Find flight deals from South Carolina to Indianapolis
Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $194 (Kiwi.com) |
One-way from | $95 (Kiwi.com) |
Popular in | August |
Cheapest in | April |
Average price | $402 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Wed 10/7
6:00 am-6:53 pm
2 stops12h 53m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$106
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Tue 9/22
3:00 pm-10:25 am
1 stop19h 25m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$108
CharlotteIndianapolis
CLT Charlotte Douglas - IND Indianapolis
CLTIND
Charlotte Douglas
Thu 11/12
11:45 am-6:57 pm
2 stops31h 12m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$115
SavannahIndianapolis
SAV Savannah/Hilton Head - IND Indianapolis
SAVIND
Savannah/Hilton Head
Tue 10/13
6:15 pm-11:00 pm
1 stop4h 45m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Thu 10/22
5:40 am-9:16 am
1 stop3h 36m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$133
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Tue 10/13
4:03 pm-7:04 pm
2 stops27h 01m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$133
CharlotteIndianapolis
CLT Charlotte Douglas - IND Indianapolis
CLTIND
Charlotte Douglas
Mon 11/9
11:45 am-10:30 am
2 stops22h 45m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$135
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Thu 10/29
5:50 am-12:05 pm
1 stop6h 15m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
CharlotteIndianapolis
CLT Charlotte Douglas - IND Indianapolis
CLTIND
Charlotte Douglas
Tue 10/13
9:42 pm-7:04 pm
2 stops21h 22m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$146
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Thu 10/8
3:04 pm-8:18 am
1 stop17h 14m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$150
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
CHS-IND
CLT-IND
GSP-IND
MYR-IND
SAV-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indianapolis
USSC-IND
CHS-IND
CLT-IND
GSP-IND
MYR-IND
What is the cheapest month to book a flight from South Carolina to Indianapolis?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $308). Flying from South Carolina to Indianapolis in April is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Indianapolis?
Airfare is below average for this route at the moment.
South Carolina to Indianapolis flights typically cost between $396 and $639 in October.The cheapest round-trip price found within the last 5 days was $194 on Multiple Airlines (Oct 1-Oct 6).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Noblesville
Bloomington
Speedway
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indianapolis by cabin class
Find flights from South Carolina to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
South Carolina and Indianapolis flights
Browse other South Carolina and Indianapolis flight options. Last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Indianapolis flights
Consider these flights traveling from South Carolina to Indianapolis.
Top 5 airlines flying from South Carolina to Indianapolis
Discover the top 5 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$133 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$183 | Average$356 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$228 | Average$335 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$270 | Average$434 | FlexibilityNo cancel fee | On-time71% |