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$100+ Cheap flights from South Carolina to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Aug 30 — Sep 61
Sun 8/30
Sun 9/6
1 adult, Economy
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Cheap flight deals from South Carolina to Indianapolis

Cheapest flights from South Carolina to Indianapolis
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2026.

This Frontier deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:56 am
CLT
-
IND
1 stop9h 42m
Frontier
Wed 9/29:59 pm
IND
-
CLT
1 stop13h 00m
Frontier
Deal found 7/26$200
This Super.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:32 am
CLT
-
IND
1 stop8h 00m
Frontier
Sat 9/196:27 pm
IND
-
CLT
1 stop14h 08m
Frontier
Deal found 7/31$206
This Frontier deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:40 pm
CLT
-
IND
1 stop11h 51m
Frontier
Thu 9/1710:26 am
IND
-
CLT
1 stop7h 55m
Frontier
Deal found 7/30$208
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:32 am
CLT
-
IND
1 stop23h 59m
Frontier
Wed 9/2311:21 am
IND
-
CLT
1 stop21h 14m
Frontier
Deal found 7/30$210
This CheapOair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:52 pm
CLT
-
IND
1 stop20h 46m
Frontier
Tue 9/18:49 pm
IND
-
CLT
1 stop19h 37m
Frontier
Deal found 7/26$211
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:16 pm
CLT
-
IND
1 stop15h 09m
Frontier
Wed 9/1611:21 am
IND
-
CLT
1 stop21h 14m
Frontier
Deal found 7/30$218
This CheapOair deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:56 am
CLT
-
IND
1 stop9h 42m
Frontier
Mon 8/317:33 pm
IND
-
CLT
1 stop21h 25m
Frontier
Deal found 7/31$224
This Super.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:32 am
CLT
-
IND
1 stop8h 00m
Frontier
Sun 9/2010:26 am
IND
-
CLT
1 stop7h 55m
Frontier
Deal found 7/30$230
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:23 pm
SAV
-
IND
1 stop26h 14m
Multiple Airlines
Wed 9/3012:39 pm
IND
-
SAV
2 stops32h 20m
Multiple Airlines
Deal found 7/27$230
This Priceline deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:45 pm
CLT
-
IND
1 stop6h 29m
Frontier
Thu 9/39:59 pm
IND
-
CLT
1 stop10h 02m
Frontier
Deal found 7/30$231
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:23 pm
CHS
-
IND
1 stop27h 15m
Multiple Airlines
Mon 8/316:11 pm
IND
-
CHS
2 stops15h 26m
Multiple Airlines
Deal found 7/27$236
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:18 am
GSP
-
IND
1 stop10h 35m
Multiple Airlines
Wed 8/196:11 pm
IND
-
GSP
2 stops41h 15m
Multiple Airlines
Deal found 7/26$238

Find flight deals from South Carolina to Indianapolis

Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated July 31, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$200
(Frontier)

One-way from

$100
(Kiwi.com)

Popular in

August

Cheapest in

April

Average price

$358

Good round-trip deal

$96 or less

Good one-way deal

$64 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From South Carolina to Indianapolis
Search Deals
One-way flight from South Carolina to Indianapolis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from South Carolina to Indianapolis.
Search Deals
Price to beat on a one-way flight from South Carolina to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2026.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 8/19

6:15 am-12:20 pm

1 stop6h 05m

Indianapolis

Sat 8/22

6:48 pm-10:38 pm

1 stop3h 50m

$271

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Thu 9/24

6:00 am-10:10 am

1 stop4h 10m

Indianapolis

Sat 9/26

5:02 pm-12:15 am

2 stops7h 13m

$290

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sun 8/23

9:07 pm-5:26 pm

2 stops20h 19m

Indianapolis

Sun 8/30

9:59 pm-7:50 am

1 stop9h 51m

$292
Quickest round-trip

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Sat 8/29

5:49 pm-9:23 pm

1 stop3h 34m

Indianapolis

Tue 9/1

7:02 am-11:09 am

1 stop4h 07m

$293

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Mon 8/24

6:35 am-2:50 pm

2 stops8h 15m

Indianapolis

Mon 8/31

5:25 am-12:40 pm

2 stops7h 15m

$295

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Tue 10/13

5:37 pm-11:44 pm

1 stop6h 07m

Indianapolis

Sat 10/17

5:40 am-2:26 pm

2 stops8h 46m

$298

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Fri 10/23

5:40 am-11:49 am

1 stop6h 09m

Indianapolis

Sun 10/25

6:00 am-10:43 am

1 stop4h 43m

$299

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Fri 11/13

8:32 pm-12:38 am

1 stop4h 06m

Indianapolis

Mon 11/16

6:04 am-10:13 am

1 stop4h 09m

$299

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Thu 10/15

5:40 am-11:49 am

1 stop6h 09m

Indianapolis

Sun 10/18

7:59 pm-11:47 pm

1 stop3h 48m

$299

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Mon 11/2

5:40 am-11:49 am

1 stop6h 09m

Indianapolis

Sun 11/8

6:00 am-9:30 am

1 stop3h 30m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indianapolis

What is the cheapest month to book a flight from South Carolina to Indianapolis?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $308). Flying from South Carolina to Indianapolis in April is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IND?

Find hourly flight availability from South Carolina to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indianapolis as you normally would.

How much does it cost to fly round-trip from South Carolina to Indianapolis?

Airfare is below average for this route at the moment.
South Carolina to Indianapolis flights typically cost between $270 and $386 in August.
The cheapest round-trip price found within the last 5 days was $236 on Multiple Airlines (Aug 24-Aug 31).

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Carolina?

    Indianapolis (IND) is the airport you will fly into if you book a flight from South Carolina to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this South Carolina to Indianapolis flight route?

    The South Carolina to Indianapolis flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Indianapolis?

    A quick flight from South Carolina to Indianapolis can take about 4h 10m. American Airlines provides one of the quickest options available for as low as $290. The distance between South Carolina and Indianapolis is about 585 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Indianapolis one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $43. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from South Carolina to Indianapolis for a low price.

  • What are the most popular routes from South Carolina to Indianapolis?

    When deciding which route to take from South Carolina to Indianapolis consider Charlotte Douglas - Indianapolis, Greenville - Indianapolis or Charleston - Indianapolis as they are the most popular.

  • What are the cheapest flights from South Carolina to Indianapolis?

    Looking at all options, your cheapest flight can be booked for $46. While the most popular route (Charlotte Douglas - Indianapolis) can be booked for $270 on average, our data indicates $102 when flying from South Carolina to Indianapolis.

  • Can I find deals for flights from South Carolina to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indianapolis.

  • Can I find deals for business class flights from South Carolina to Indianapolis?

    Yes. Cheapflights offers flight deals from South Carolina to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indianapolis?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $308). Flying from South Carolina to Indianapolis in April is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Kokomo
Fishers
Westfield
Franklin
Mooresville
Plainfield
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Indianapolis

Discover the top 5 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$138FlexibilityNo cancel feeOn-time88%
DeltaCheapest$183Average$369FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$189Average$386FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$190Average$269FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$270Average$438FlexibilityNo cancel feeOn-time71%

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