$101+ Cheap flights from South Carolina to Indianapolis (IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Nov 30 — Dec 71
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Indianapolis
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Cheapest flights from South Carolina to IndianapolisExplore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:42 pm -
1 stop21h 11m
Wed 11/1812:38 pm -
1 stop19h 16m
Deal found 10/31![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:13 pm -
1 stop19h 07m
Mon 11/2310:56 am -
1 stop10h 05m
Deal found 10/28![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:42 pm -
1 stop21h 11m
Mon 11/1612:38 pm -
2 stops26h 51m
Deal found 10/30![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:09 pm -
1 stop16h 16m
Sat 12/511:04 am -
1 stop21h 34m
Deal found 10/28![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:09 pm -
1 stop16h 16m
Sat 12/1211:04 am -
1 stop21h 34m
Deal found 10/28![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:10 pm -
1 stop21h 10m
Mon 11/3010:56 am -
1 stop22h 59m
Deal found 10/27![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:21 pm -
2 stops22h 32m
Sat 11/1412:38 pm -
1 stop6h 36m
Deal found 10/26![Multiple Airlines logo]()
$240
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:10 pm -
1 stop4h 53m
Tue 11/246:00 am -
1 stop5h 07m
Deal found 10/27![Delta logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:54 pm -
1 stop25h 00m
Sat 11/1412:38 pm -
1 stop6h 36m
Deal found 10/28![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:12 pm -
2 stops17h 41m
Tue 11/171:33 pm -
1 stop19h 40m
Deal found 10/29![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:42 pm -
1 stop26h 38m
Fri 11/2710:56 am -
1 stop20h 58m
Deal found 10/28![Multiple Airlines logo]()
$262
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:40 am -
1 stop4h 58m
Fri 12/118:00 am -
1 stop5h 22m
Deal found 10/29![Delta logo]()
$267
Best flights from South Carolina to IndianapolisDiscover carefully curated flight deals from South Carolina to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
Discover carefully curated flight deals from South Carolina to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:42 pm -
1 stop21h 11m
Mon 11/1612:38 pm -
2 stops26h 51m
Deal found 10/30![Multiple Airlines logo]()
$212
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:10 pm -
1 stop4h 53m
Tue 11/246:00 am -
1 stop5h 07m
Deal found 10/27![Delta logo]()
$247
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
2 stops10h 25m
Fri 12/115:30 am -
1 stop4h 40m
Deal found 10/28![Southwest logo]()
$272
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:20 am -
1 stop6h 24m
Thu 11/267:10 am -
2 stops7h 06m
Deal found 10/30![United Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:39 am -
1 stop6h 22m
Sun 12/136:00 am -
1 stop4h 30m
Deal found 10/26![American Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:40 am -
1 stop4h 58m
Fri 12/118:00 am -
1 stop5h 22m
Deal found 10/29![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:30 pm -
2 stops9h 20m
Sat 12/125:30 am -
2 stops7h 45m
Deal found 10/28![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
1 stop5h 56m
Thu 11/2611:35 am -
1 stop4h 36m
Deal found 10/30![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:05 am -
1 stop5h 51m
Tue 1/55:28 am -
2 stops6h 47m
Deal found 10/30![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:39 pm -
1 stop19h 39m
Sun 11/2210:56 am -
1 stop21h 17m
Deal found 10/26![Multiple Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/155:25 pm -
1 stop4h 33m
Mon 4/194:50 pm -
2 stops6h 52m
Deal found 10/27![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:00 am -
1 stop4h 20m
Mon 11/2311:35 am -
2 stops9h 25m
Deal found 10/29![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop4h 33m
Thu 12/36:43 am -
1 stop3h 58m
Deal found 10/29![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:00 am -
2 stops7h 24m
Sun 12/139:00 am -
1 stop4h 54m
Deal found 10/26![United Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:55 am -
2 stops8h 50m
Fri 12/255:30 am -
1 stop4h 50m
Deal found 10/30![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:47 pm -
1 stop6h 49m
Fri 11/277:54 am -
1 stop6h 24m
Deal found 10/29![American Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:30 am -
1 stop4h 35m
Sun 12/135:10 am -
2 stops10h 15m
Deal found 10/28![Southwest logo]()
$323
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:51 pm -
1 stop5h 49m
Sat 11/286:34 am -
1 stop4h 06m
Deal found 10/29![Delta logo]()
$338
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/84:25 pm -
1 stop4h 53m
Wed 1/1311:20 am -
1 stop4h 33m
Deal found 10/28![American Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:13 pm -
1 stop19h 07m
Sun 11/2910:30 pm -
2 stops34h 08m
Deal found 10/27![Multiple Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:45 pm -
1 stop5h 35m
Wed 12/304:20 pm -
2 stops7h 55m
Deal found 10/29![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/156:00 am -
2 stops10h 19m
Mon 1/187:00 am -
1 stop6h 46m
Deal found 10/30![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:55 am -
2 stops8h 50m
Mon 12/215:50 pm -
2 stops6h 25m
Deal found 10/26![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/279:55 am -
2 stops10h 25m
Wed 3/311:00 am -
1 stop6h 24m
Deal found 10/27![United Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:33 pm -
1 stop5h 10m
Sun 12/136:00 am -
1 stop4h 32m
Deal found 10/28![American Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:18 pm -
1 stop4h 03m
Thu 1/149:00 am -
1 stop7h 33m
Deal found 10/27![Delta logo]()
$391
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:50 am -
1 stop6h 55m
Mon 11/305:35 pm -
1 stop4h 20m
Deal found 10/27![Southwest logo]()
$338
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:16 am -
2 stops7h 36m
Sun 11/155:45 am -
1 stop4h 14m
Deal found 10/29![United Airlines logo]()
$428
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/68:00 am -
2 stops8h 45m
Tue 1/127:05 am -
2 stops10h 20m
Deal found 10/27![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:16 am -
2 stops7h 25m
Sun 11/296:00 am -
2 stops8h 17m
Deal found 10/28![United Airlines logo]()
$434
Last-minute flights from South Carolina to IndianapolisDiscover last-minute flight deals from South Carolina to Indianapolis. Data last updated October 31, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indianapolis. Data last updated October 31, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:21 pm -
2 stops22h 32m
Sat 11/1412:38 pm -
1 stop6h 36m
Deal found 10/26![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:54 pm -
1 stop25h 00m
Sat 11/1412:38 pm -
1 stop6h 36m
Deal found 10/28![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:42 pm -
1 stop21h 11m
Wed 11/1812:38 pm -
1 stop19h 16m
Deal found 10/31![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:42 pm -
1 stop21h 11m
Mon 11/1612:38 pm -
2 stops26h 51m
Deal found 10/30![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:12 pm -
2 stops17h 41m
Tue 11/171:33 pm -
1 stop19h 40m
Deal found 10/29![Multiple Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:10 pm -
1 stop4h 53m
Tue 11/246:00 am -
1 stop5h 07m
Deal found 10/27![Delta logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:13 pm -
1 stop19h 07m
Mon 11/2310:56 am -
1 stop10h 05m
Deal found 10/28![Multiple Airlines logo]()
$207
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
1 stop5h 56m
Thu 11/2611:35 am -
1 stop4h 36m
Deal found 10/30![Delta logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:42 pm -
1 stop26h 38m
Fri 11/2710:56 am -
1 stop20h 58m
Deal found 10/28![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:10 pm -
1 stop21h 10m
Mon 11/3010:56 am -
1 stop22h 59m
Deal found 10/27![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:44 pm -
1 stop28h 36m
Mon 11/3010:56 am -
2 stops28h 33m
Deal found 10/30![Multiple Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop4h 33m
Thu 12/36:43 am -
1 stop3h 58m
Deal found 10/29![Delta logo]()
$279
One-way flights from South Carolina to IndianapolisSearch for one-way flight options from South Carolina to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
Search for one-way flight options from South Carolina to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:03 pm -
1 stop19h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:45 am -
3 stops12h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:52 pm -
2 stops15h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$121
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
1 stop5h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:58 pm -
2 stops14h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:12 pm -
2 stops17h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:55 pm -
1 stop4h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$136
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:51 pm -
1 stop5h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:50 pm -
1 stop17h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:13 pm -
1 stop13h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:15 pm -
1 stop15h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:15 pm -
1 stop17h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$151
Find flight deals from South Carolina to Indianapolis
Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated October 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $156 (Kiwi.com) |
One-way from | $101 (Kiwi.com) |
Popular in | August |
Cheapest in | October |
Average price | $270 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Fri 11/6
2:42 pm-11:53 am
1 stop21h 11m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$123
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Sat 12/5
7:00 am-12:59 pm
1 stop5h 59m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$124
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Fri 11/13
8:58 pm-11:53 am
2 stops14h 55m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Fri 11/6
6:12 pm-11:53 am
2 stops17h 41m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$130
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Wed 11/25
7:55 pm-12:45 am
1 stop4h 50m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Thu 12/10
6:00 am-12:40 pm
1 stop6h 40m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Tue 11/24
4:50 pm-10:01 am
1 stop17h 11m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$142
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 11/5
8:15 pm-11:53 am
1 stop15h 38m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$146
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Thu 2/18
6:30 am-12:46 pm
1 stop6h 16m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Fri 2/19
6:30 am-10:32 am
1 stop4h 02m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
MYR-IND
CHS-IND
GSP-IND
CAE-IND
HHH-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indianapolis
USSC-IND
MYR-IND
CHS-IND
GSP-IND
CAE-IND
What is the cheapest month to book a flight from South Carolina to Indianapolis?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $334). Flying from South Carolina to Indianapolis in April is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Indianapolis?
Airfare is below average for this route at the moment.
South Carolina to Indianapolis flights typically cost between $262 and $446 in November.The cheapest round-trip price found within the last 5 days was $207 on Multiple Airlines (Nov 19-Nov 23).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsPlainfield
Greenwood
Terre Haute
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Bloomington
Noblesville
Speedway
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indianapolis by cabin class
Find flights from South Carolina to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 31, 2026.
South Carolina and Indianapolis flights
Browse other South Carolina and Indianapolis flight options. Last updated on October 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Indianapolis flights
Consider these flights traveling from South Carolina to Indianapolis.
Top 5 airlines flying from South Carolina to Indianapolis
Discover the top 5 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$133 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$183 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$270 | Average$448 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$310 | Average$447 | FlexibilityNo cancel fee | On-time69% |