$89+ Cheap flights from South Carolina to Indianapolis (IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Sep 16 — Sep 231
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to IndianapolisExplore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:54 pm -
1 stop18h 11m
Mon 9/149:20 pm -
1 stop11h 15m
Deal found 8/17![Frontier logo]()
$178
This Frontier deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:40 pm -
1 stop11h 51m
Mon 9/219:20 pm -
1 stop11h 15m
Deal found 8/16![Frontier logo]()
$179
This CheapOair deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:40 pm -
1 stop21h 06m
Sat 9/126:27 pm -
1 stop14h 08m
Deal found 8/14![Frontier logo]()
$188
This Expedia deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:32 am -
1 stop10h 59m
Mon 9/149:20 pm -
1 stop11h 15m
Deal found 8/15![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:40 pm -
1 stop11h 51m
Wed 9/234:12 pm -
1 stop26h 47m
Deal found 8/14![Frontier logo]()
$194
This CheapOair deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:45 pm -
1 stop19h 33m
Sat 9/196:27 pm -
1 stop14h 08m
Deal found 8/14![Frontier logo]()
$201
This Expedia deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:32 am -
1 stop10h 59m
Fri 9/189:20 pm -
1 stop11h 15m
Deal found 8/14![Frontier logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:32 am -
1 stop9h 14m
Mon 9/217:48 pm -
2 stops36h 47m
Deal found 8/16![Frontier logo]()
$205
This CheapOair deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:47 pm -
1 stop19h 14m
Wed 10/1410:22 pm -
1 stop12h 43m
Deal found 8/15![Frontier logo]()
$207
This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:46 pm -
1 stop6h 34m
Sat 11/1410:44 am -
1 stop5h 54m
Deal found 8/14![Frontier logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:18 am -
1 stop25h 07m
Mon 9/217:48 pm -
2 stops26h 48m
Deal found 8/15![Multiple Airlines logo]()
$220
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:48 pm -
1 stop3h 25m
Mon 9/76:00 am -
1 stop3h 39m
Deal found 8/13![American Airlines logo]()
$221
Best flights from South Carolina to IndianapolisDiscover carefully curated flight deals from South Carolina to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from South Carolina to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:40 pm -
2 stops21h 13m
Tue 9/2211:21 am -
1 stop21h 14m
Deal found 8/17![Frontier logo]()
$223
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:20 pm -
2 stops7h 45m
Wed 9/165:50 am -
1 stop4h 25m
Deal found 8/12![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:35 am -
1 stop3h 55m
Wed 9/95:18 pm -
1 stop6h 37m
Deal found 8/12![Delta logo]()
$259
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:20 am -
1 stop4h 36m
Thu 10/85:40 am -
1 stop4h 18m
Deal found 8/13![United Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:25 pm -
1 stop4h 16m
Wed 9/166:00 am -
1 stop5h 37m
Deal found 8/14![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:50 pm -
1 stop4h 50m
Tue 10/206:50 am -
2 stops6h 40m
Deal found 8/13![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop4h 26m
Mon 10/56:00 am -
1 stop4h 07m
Deal found 8/15![Delta logo]()
$271
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:40 am -
2 stops8h 10m
Mon 9/75:25 am -
1 stop4h 50m
Deal found 8/12![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:56 pm -
1 stop4h 26m
Mon 10/56:38 pm -
1 stop4h 50m
Deal found 8/15![Delta logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:23 am -
2 stops9h 37m
Sun 10/255:45 am -
1 stop4h 14m
Deal found 8/15![United Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:10 am -
2 stops8h 30m
Thu 11/125:40 am -
2 stops7h 20m
Deal found 8/13![Southwest logo]()
$269
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:45 pm -
1 stop5h 56m
Sun 9/206:11 am -
1 stop4h 22m
Deal found 8/17![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:00 am -
2 stops7h 34m
Mon 9/76:00 am -
1 stop4h 36m
Deal found 8/13![United Airlines logo]()
$305
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:56 pm -
1 stop4h 26m
Mon 10/56:00 am -
1 stop4h 07m
Deal found 8/15![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:40 am -
2 stops7h 10m
Tue 9/812:15 pm -
1 stop7h 05m
Deal found 8/12![Southwest logo]()
$270
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:45 am -
2 stops7h 02m
Mon 9/217:00 am -
2 stops7h 50m
Deal found 8/13![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:58 pm -
1 stop4h 26m
Tue 10/136:00 am -
1 stop4h 07m
Deal found 8/17![Delta logo]()
$287
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:18 am -
1 stop6h 43m
Sun 9/278:00 pm -
1 stop4h 02m
Deal found 8/17![American Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:35 am -
2 stops8h 15m
Mon 9/145:20 pm -
1 stop4h 35m
Deal found 8/17![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:53 am -
1 stop5h 30m
Fri 11/276:00 am -
1 stop5h 08m
Deal found 8/15![Delta logo]()
$296
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:10 am -
1 stop6h 32m
Mon 10/53:03 pm -
1 stop6h 45m
Deal found 8/13![United Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:10 am -
1 stop4h 46m
Sun 9/278:00 pm -
1 stop3h 55m
Deal found 8/16![American Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:53 pm -
1 stop4h 35m
Sun 10/256:00 am -
1 stop4h 43m
Deal found 8/15![Delta logo]()
$296
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:40 am -
2 stops9h 25m
Mon 10/196:20 am -
2 stops12h 55m
Deal found 8/14![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:18 pm -
1 stop5h 56m
Tue 9/85:45 am -
2 stops9h 18m
Deal found 8/12![United Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am -
1 stop6h 03m
Sat 9/196:57 pm -
1 stop4h 01m
Deal found 8/16![American Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:09 pm -
1 stop6h 16m
Sat 9/196:00 am -
1 stop5h 12m
Deal found 8/14![Delta logo]()
$296
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/73:00 pm -
2 stops8h 41m
Mon 1/1112:51 pm -
1 stop4h 34m
Deal found 8/12![United Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:45 am -
2 stops5h 25m
Sat 9/198:10 am -
2 stops7h 45m
Deal found 8/16![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:19 pm -
1 stop5h 06m
Wed 10/217:00 am -
1 stop6h 14m
Deal found 8/16![Delta logo]()
$296
Last-minute flights from South Carolina to IndianapolisDiscover last-minute flight deals from South Carolina to Indianapolis. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indianapolis. Data last updated August 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:48 pm -
1 stop3h 25m
Mon 9/76:00 am -
1 stop3h 39m
Deal found 8/13![American Airlines logo]()
$221
This CheapOair deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:45 pm -
1 stop19h 33m
Sat 9/196:27 pm -
1 stop14h 08m
Deal found 8/14![Frontier logo]()
$201
This CheapOair deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:40 pm -
1 stop21h 06m
Sat 9/126:27 pm -
1 stop14h 08m
Deal found 8/14![Frontier logo]()
$188
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:54 pm -
1 stop18h 11m
Mon 9/149:20 pm -
1 stop11h 15m
Deal found 8/17![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:32 am -
1 stop9h 14m
Mon 9/217:48 pm -
2 stops36h 47m
Deal found 8/16![Frontier logo]()
$205
This Expedia deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:32 am -
1 stop10h 59m
Mon 9/149:20 pm -
1 stop11h 15m
Deal found 8/15![Frontier logo]()
$191
This Expedia deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:32 am -
1 stop10h 59m
Fri 9/189:20 pm -
1 stop11h 15m
Deal found 8/14![Frontier logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:18 am -
1 stop25h 07m
Mon 9/217:48 pm -
2 stops26h 48m
Deal found 8/15![Multiple Airlines logo]()
$220
This Frontier deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:40 pm -
1 stop11h 51m
Mon 9/219:20 pm -
1 stop11h 15m
Deal found 8/16![Frontier logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:40 pm -
1 stop11h 51m
Tue 9/2211:21 am -
1 stop21h 14m
Deal found 8/16![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:32 am -
1 stop9h 14m
Mon 9/217:48 pm -
2 stops36h 47m
Deal found 8/16![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:40 pm -
1 stop11h 51m
Wed 9/234:12 pm -
1 stop26h 47m
Deal found 8/14![Frontier logo]()
$194
One-way flights from South Carolina to IndianapolisSearch for one-way flight options from South Carolina to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from South Carolina to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:13 pm -
1 stop7h 14m
Deal found 8/14![Frontier logo]()
$89
This Super.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:32 am -
1 stop23h 59m
Deal found 8/17![Frontier logo]()
$93
This Super.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:32 am -
1 stop24h 53m
Deal found 8/15![Frontier logo]()
$94
This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:40 pm -
1 stop11h 51m
Deal found 8/14![Frontier logo]()
$95
This CheapOair deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:44 pm -
1 stop23h 56m
Deal found 8/15![Frontier logo]()
$100
This Frontier deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:05 pm -
1 stop7h 55m
Deal found 8/15![Frontier logo]()
$102
This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:05 pm -
1 stop9h 22m
Deal found 8/14![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops12h 53m
Deal found 8/17![Multiple Airlines logo]()
$113
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:47 pm -
1 stop4h 09m
Deal found 8/13![United Airlines logo]()
$117
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:45 am -
1 stop3h 51m
Deal found 8/13![Delta logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:07 am -
2 stops32h 46m
Deal found 8/13![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:39 pm -
1 stop28h 06m
Deal found 8/14![Allegiant Air logo]()
$122
Find flight deals from South Carolina to Indianapolis
Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated August 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $178 (Expedia) |
One-way from | $89 (Frontier) |
Popular in | August |
Cheapest in | April |
Average price | $546 |
Good round-trip deal | $96 or less |
Good one-way deal | $86 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteIndianapolis
CLT Charlotte Douglas - IND Indianapolis
CLTIND
Charlotte Douglas
Tue 9/15
9:40 pm-6:53 pm
2 stops21h 13m
Indianapolis
Tue 9/22
11:21 am-8:35 am
1 stop21h 14m
$223
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Wed 9/9
1:20 pm-9:05 pm
2 stops7h 45m
Indianapolis
Wed 9/16
5:50 am-10:15 am
1 stop4h 25m
$239
SavannahIndianapolis
SAV Savannah/Hilton Head - IND Indianapolis
SAVIND
Savannah/Hilton Head
Thu 9/3
6:35 am-10:30 am
1 stop3h 55m
Indianapolis
Wed 9/9
5:18 pm-11:55 pm
1 stop6h 37m
$259
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 10/15
7:50 pm-12:40 am
1 stop4h 50m
Indianapolis
Tue 10/20
6:50 am-1:30 pm
2 stops6h 40m
$262
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Mon 10/5
6:20 am-10:56 am
1 stop4h 36m
Indianapolis
Thu 10/8
5:40 am-9:58 am
1 stop4h 18m
$264
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 9/3
6:40 am-2:50 pm
2 stops8h 10m
Indianapolis
Mon 9/7
5:25 am-10:15 am
1 stop4h 50m
$264
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Tue 11/10
8:10 am-4:40 pm
2 stops8h 30m
Indianapolis
Thu 11/12
5:40 am-1:00 pm
2 stops7h 20m
$269
SavannahIndianapolis
SAV Savannah/Hilton Head - IND Indianapolis
SAVIND
Savannah/Hilton Head
Thu 9/3
7:40 am-2:50 pm
2 stops7h 10m
Indianapolis
Tue 9/8
12:15 pm-7:20 pm
1 stop7h 05m
$270
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Mon 9/14
7:25 pm-11:41 pm
1 stop4h 16m
Indianapolis
Wed 9/16
6:00 am-11:37 am
1 stop5h 37m
$271
Quickest round-trip
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Sat 10/3
6:00 am-10:26 am
1 stop4h 26m
Indianapolis
Mon 10/5
6:00 am-10:07 am
1 stop4h 07m
$271
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
CLT-IND
CHS-IND
GSP-IND
SAV-IND
MYR-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indianapolis
USSC-IND
CLT-IND
CHS-IND
GSP-IND
SAV-IND
What is the cheapest month to book a flight from South Carolina to Indianapolis?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $308). Flying from South Carolina to Indianapolis in April is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Indianapolis?
Airfare is below average for this route at the moment.
South Carolina to Indianapolis flights typically cost between $345 and $592 in September.The cheapest round-trip price found within the last 5 days was $220 on Multiple Airlines (Sep 15-Sep 21).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Muncie
Plainfield
Greenwood
Fishers
Kokomo
Westfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Indianapolis
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Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indianapolis by cabin class
Find flights from South Carolina to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
South Carolina and Indianapolis flights
Browse other South Carolina and Indianapolis flight options. Last updated on August 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Indianapolis flights
Consider these flights traveling from South Carolina to Indianapolis.
Top 5 airlines flying from South Carolina to Indianapolis
Discover the top 5 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$133 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$183 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$190 | Average$269 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$396 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$273 | Average$433 | FlexibilityNo cancel fee | On-time71% |