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$38+ Cheap flights from South Carolina to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheap flight deals from South Carolina to Indianapolis

Cheapest flights from South Carolina to Indianapolis
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This Booking.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:30 am
SAV
-
IND
Nonstop1h 51m
Allegiant Air
Mon 5/1111:11 am
IND
-
SAV
Nonstop1h 44m
Allegiant Air
Deal found 3/29$90
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/199:30 pm
CHS
-
IND
Nonstop1h 56m
Allegiant Air
Mon 6/226:52 pm
IND
-
CHS
Nonstop1h 48m
Allegiant Air
Deal found 3/31$92
This Cheapflightsfares deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:31 pm
CHS
-
IND
Nonstop1h 54m
Allegiant Air
Mon 7/66:51 pm
IND
-
CHS
Nonstop1h 50m
Allegiant Air
Deal found 3/28$99
This Booking.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:30 am
SAV
-
IND
Nonstop1h 51m
Allegiant Air
Mon 5/1111:11 am
IND
-
SAV
Nonstop1h 44m
Allegiant Air
Deal found 3/29$109
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:33 pm
CHS
-
IND
Nonstop2h 00m
Allegiant Air
Fri 5/294:15 pm
IND
-
CHS
Nonstop1h 49m
Allegiant Air
Deal found 3/28$131
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:31 pm
CLT
-
IND
1 stop8h 27m
Spirit Airlines
Sat 4/1812:07 pm
IND
-
CLT
1 stop8h 30m
Spirit Airlines
Deal found 3/31$135
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 pm
CLT
-
IND
1 stop17h 41m
Frontier
Sat 5/210:44 am
IND
-
CLT
1 stop5h 51m
Frontier
Deal found 3/28$139
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:09 pm
CLT
-
IND
1 stop11h 29m
Frontier
Thu 4/237:13 pm
IND
-
CLT
1 stop21h 17m
Frontier
Deal found 3/30$140
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:09 pm
CLT
-
IND
1 stop15h 02m
Frontier
Sat 5/210:44 am
IND
-
CLT
1 stop5h 51m
Frontier
Deal found 3/28$144
This Booking.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:30 am
SAV
-
IND
Nonstop1h 51m
Allegiant Air
Mon 4/1311:11 am
IND
-
SAV
Nonstop1h 44m
Allegiant Air
Deal found 3/27$150
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 pm
CLT
-
IND
1 stop17h 41m
Frontier
Thu 4/237:13 pm
IND
-
CLT
1 stop21h 17m
Frontier
Deal found 3/31$151
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:09 pm
CLT
-
IND
1 stop15h 02m
Multiple Airlines
Mon 5/46:40 pm
IND
-
CLT
1 stop17h 25m
Multiple Airlines
Deal found 3/28$152

Find flight deals from South Carolina to Indianapolis

Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$90
(Booking.com)

One-way from

$38
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$433

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From South Carolina to Indianapolis
Search Deals
One-way flight from South Carolina to Indianapolis
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a one-way flight from South Carolina to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Sat 5/30

5:40 am-10:14 am

1 stop4h 34m

Indianapolis

Wed 6/3

10:10 am-3:07 pm

1 stop4h 57m

$231

AugustaIndianapolis

AGS - IND

AGSIND

Augusta Bush Field

Wed 7/1

5:00 am-9:04 am

1 stop4h 04m

Indianapolis

Tue 7/7

2:59 pm-9:48 pm

1 stop6h 49m

$267

AugustaIndianapolis

AGS - IND

AGSIND

Augusta Bush Field

Thu 7/16

8:29 pm-12:41 am

1 stop4h 12m

Indianapolis

Tue 7/21

10:07 am-3:27 pm

1 stop5h 20m

$267

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Fri 5/15

7:17 pm-12:33 am

1 stop5h 16m

Indianapolis

Wed 5/20

8:07 am-3:54 pm

1 stop7h 47m

$270

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Mon 4/13

6:42 pm-4:13 pm

2 stops21h 31m

Indianapolis

Fri 4/17

11:27 am-5:52 pm

1 stop6h 25m

$275

AugustaIndianapolis

AGS - IND

AGSIND

Augusta Bush Field

Tue 4/28

6:22 pm-12:41 am

1 stop6h 19m

Indianapolis

Tue 5/5

10:10 am-2:10 pm

1 stop4h 00m

$277

AugustaIndianapolis

AGS - IND

AGSIND

Augusta Bush Field

Tue 4/28

1:21 pm-9:24 pm

2 stops8h 03m

Indianapolis

Tue 5/5

3:18 pm-9:50 pm

1 stop6h 32m

$282

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/15

11:28 am-11:59 pm

1 stop12h 31m

Indianapolis

Sun 4/19

5:30 am-11:29 pm

1 stop17h 59m

$283

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Thu 6/4

3:14 pm-8:13 pm

1 stop4h 59m

Indianapolis

Mon 6/8

6:00 am-10:23 am

1 stop4h 23m

$291
Quickest round-trip

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Wed 5/13

5:00 am-9:41 am

1 stop4h 41m

Indianapolis

Wed 5/20

8:08 pm-11:53 pm

1 stop3h 45m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indianapolis

What is the cheapest month to book a flight from South Carolina to Indianapolis?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $40). Flying from South Carolina to Indianapolis in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IND?

Find hourly flight availability from South Carolina to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2026.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Indianapolis in the afternoon. If you’re flexible enough to do this you can expect to save up to 80% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from South Carolina to Indianapolis?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Indianapolis. Price data was last updated on March 28, 2026.

Travelers seeking maximum savings on their South Carolina to Indianapolis flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from South Carolina to Indianapolis?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Carolina?

    Indianapolis (IND) is the airport you will fly into if you book a flight from South Carolina to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this South Carolina to Indianapolis flight route?

    The South Carolina to Indianapolis flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Indianapolis?

    A quick flight from South Carolina to Indianapolis can take about 4h 04m. Delta provides one of the quickest options available for as low as $267. The distance between South Carolina and Indianapolis is about 500 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Indianapolis one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $153. However, be on the lookout for offers from Delta and Frontier, as they are both options that can get you from South Carolina to Indianapolis for a low price.

  • What are the most popular routes from South Carolina to Indianapolis?

    When deciding which route to take from South Carolina to Indianapolis consider Charlotte Douglas - Indianapolis, Charleston - Indianapolis or Greenville - Indianapolis as they are the most popular.

  • Can I find deals for flights from South Carolina to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indianapolis.

  • Can I find deals for business class flights from South Carolina to Indianapolis?

    Yes. Cheapflights offers flight deals from South Carolina to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indianapolis?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $40). Flying from South Carolina to Indianapolis in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Greenwood
Noblesville
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Bloomington
Crawfordsville

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Indianapolis

Discover the top 5 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$45Average$123FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$83Average$201FlexibilityNo cancel feeOn-time65%
DeltaCheapest$183Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$190Average$306FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$414FlexibilityNo cancel feeOn-time71%

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