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$259+ Cheap flights from Santa Fe to Indianapolis (SAF - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — IND
Apr 11 — Apr 181
Sat 4/11
Sat 4/18
1 adult, Economy
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Cheap flight deals from Santa Fe to Indianapolis

Cheapest flights from Santa Fe to Indianapolis
Explore the most affordable flight options available from Santa Fe to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:04 pm
SAF
-
IND
1 stop7h 53m
American Airlines
Wed 5/136:00 am
IND
-
SAF
1 stop6h 07m
American Airlines
Deal found 3/9$294
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:56 am
SAF
-
IND
1 stop10h 03m
American Airlines
Sun 4/196:00 am
IND
-
SAF
1 stop6h 07m
American Airlines
Deal found 3/8$309
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:19 pm
SAF
-
IND
1 stop7h 35m
United Airlines
Sun 4/197:15 am
IND
-
SAF
2 stops9h 33m
United Airlines
Deal found 3/8$377
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:31 pm
SAF
-
IND
1 stop4h 57m
United Airlines
Sat 5/168:00 am
IND
-
SAF
1 stop6h 38m
United Airlines
Deal found 3/12$394
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:19 pm
SAF
-
IND
2 stops8h 12m
United Airlines
Sat 5/168:00 am
IND
-
SAF
1 stop6h 38m
United Airlines
Deal found 3/11$404
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:56 am
SAF
-
IND
1 stop10h 03m
American Airlines
Tue 5/126:00 am
IND
-
SAF
1 stop6h 07m
American Airlines
Deal found 3/9$409
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:24 pm
SAF
-
IND
1 stop5h 30m
United Airlines
Sat 4/183:38 pm
IND
-
SAF
1 stop7h 00m
United Airlines
Deal found 3/8$415
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:56 am
SAF
-
IND
2 stops10h 01m
American Airlines
Tue 5/126:00 am
IND
-
SAF
1 stop6h 07m
American Airlines
Deal found 3/9$419

Find flight deals from Santa Fe to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.

Round-trip from

$294
(American Airlines)

One-way from

$259
(United Airlines)

Popular in

March

Cheapest in

April

Average price

$873
From Santa Fe to Indianapolis
Search Deals
One-way flight from Santa Fe to Indianapolis
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Santa Fe to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Thu 4/16

1:19 pm-10:54 pm

1 stop7h 35m

Indianapolis

Sun 4/19

7:15 am-2:48 pm

2 stops9h 33m

$377
Quickest round-trip

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Thu 5/7

3:31 pm-10:28 pm

1 stop4h 57m

Indianapolis

Sat 5/16

8:00 am-12:38 pm

1 stop6h 38m

$394

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 4/15

7:00 am-2:36 pm

1 stop5h 36m

Indianapolis

Sat 4/18

11:04 am-8:38 pm

2 stops11h 34m

$425

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Sat 5/9

3:31 pm-10:28 pm

1 stop4h 57m

Indianapolis

Sun 5/10

8:00 am-12:38 pm

1 stop6h 38m

$435

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Thu 5/7

3:31 pm-10:28 pm

1 stop4h 57m

Indianapolis

Tue 5/12

6:00 am-12:38 pm

2 stops8h 38m

$445

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 5/6

1:19 pm-12:59 am

2 stops9h 40m

Indianapolis

Tue 5/12

5:45 am-2:50 pm

2 stops11h 05m

$450

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Tue 5/5

3:31 pm-10:28 pm

1 stop4h 57m

Indianapolis

Mon 5/11

7:01 pm-12:38 pm

1 stop19h 37m

$487

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 5/6

3:31 pm-10:28 pm

1 stop4h 57m

Indianapolis

Mon 5/11

7:01 pm-9:24 am

1 stop16h 23m

$487
Cheapest one-way
Quickest one-way

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Tue 3/31

7:00 am-2:36 pm

1 stop5h 36m

$259

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 3/25

7:00 am-10:59 pm

2 stops13h 59m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Sorted by cheapest first

Best time to book a flight from Santa Fe to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Indianapolis

What is the cheapest month to book a flight from Santa Fe to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Santa Fe to Indianapolis (average of $235). Flying from Santa Fe to Indianapolis in February is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated March 12, 2026.
Get a feel of what it's like to fly with American Airlines from Santa Fe to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,446 reviews

Entertainment

6.9

Overall

7.1

Comfort

7.2

Crew

7.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,446 reviews
American Airlines
7.1
Good
11,446 reviews

Entertainment

6.9

Overall

7.1

Comfort

7.2

Crew

7.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to Indianapolis?

    Departing from Santa Fe to Indianapolis will take you 4h 57m. The distance between Santa Fe and Indianapolis is about 1116 mi.

  • What is the cheapest airline to fly from Santa Fe to Indianapolis round-trip?

    Currently priced at $299, American Airlines will fly you from Santa Fe to Indianapolis and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is priced at 40% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santa Fe to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Indianapolis.

  • Can I find deals for business class flights from Santa Fe to Indianapolis?

    Yes. Cheapflights offers flight deals from Santa Fe to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Santa Fe to Indianapolis (average of $235). Flying from Santa Fe to Indianapolis in February is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Mooresville
Franklin
Anderson
Carmel
Kokomo
Crawfordsville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Santa Fe to Indianapolis

Discover the top airline that operate flights from Santa Fe to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$299Average$464FlexibilityNo cancel feeOn-time71%

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