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$229+ Cheap flights from Santa Fe to Indianapolis (SAF - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — IND
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Santa Fe to Indianapolis

Cheapest flights from Santa Fe to Indianapolis
Explore the most affordable flight options available from Santa Fe to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:28 am
SAF
-
IND
1 stop5h 15m
American Airlines
Sun 2/156:46 am
IND
-
SAF
1 stop8h 27m
American Airlines
Deal found 1/27$304
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/111:16 pm
SAF
-
IND
2 stops8h 14m
United Airlines
Sun 2/156:00 am
IND
-
SAF
2 stops8h 47m
United Airlines
Deal found 1/27$335
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:00 am
SAF
-
IND
1 stop5h 36m
United Airlines
Sat 2/213:42 pm
IND
-
SAF
1 stop6h 49m
United Airlines
Deal found 1/26$395

Find flight deals from Santa Fe to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Round-trip from

$304
(American Airlines)

One-way from

$229
(American Airlines)

Popular in

March

Cheapest in

February

Average price

$270
From Santa Fe to Indianapolis
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One-way flight from Santa Fe to Indianapolis
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Highest demand for flights based on searches. 3% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santa Fe to Indianapolis that are best for you.

Fly from

Santa Fe

Fly to

Indianapolis

Route

Depart

Return

Price

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Thu 2/12

4:15 pm-11:59 pm

1 stop5h 44m

Indianapolis

Mon 2/16

5:49 am-9:39 am

1 stop5h 50m

$304

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 2/11

10:28 am-5:43 pm

1 stop5h 15m

Indianapolis

Sun 2/15

5:49 am-3:05 pm

2 stops11h 16m

$314

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 2/11

1:16 pm-11:30 pm

2 stops8h 14m

Indianapolis

Sun 2/15

6:00 am-12:47 pm

2 stops8h 47m

$335

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 2/18

7:00 am-2:36 pm

1 stop5h 36m

Indianapolis

Sat 2/21

3:42 pm-8:31 pm

1 stop6h 49m

$395

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Sun 3/8

2:35 pm-12:16 am

1 stop7h 41m

$229

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Mon 3/9

3:20 pm-10:20 pm

1 stop5h 00m

$229

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Sun 3/8

6:09 pm-3:49 pm

2 stops19h 40m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Best time to book a flight from Santa Fe to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Indianapolis

What is the cheapest month to book a flight from Santa Fe to Indianapolis?

Currently, January is the cheapest month in which you can book a flight from Santa Fe to Indianapolis (average of $175). Flying from Santa Fe to Indianapolis in December is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with American Airlines from Santa Fe to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,206 reviews

Entertainment

6.9

Food

6.4

Comfort

7.2

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,206 reviews
American Airlines
7.2
Good
11,206 reviews

Entertainment

6.9

Food

6.4

Comfort

7.2

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to Indianapolis?

    Departing from Santa Fe to Indianapolis will take you 5h 15m. The distance between Santa Fe and Indianapolis is about 1116 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santa Fe to Indianapolis round-trip?

    Currently priced at $254, American Airlines will fly you from Santa Fe to Indianapolis and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is priced at 48% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santa Fe to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Indianapolis.

  • Can I find deals for business class flights from Santa Fe to Indianapolis?

    Yes. Cheapflights offers flight deals from Santa Fe to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Indianapolis?

    Currently, January is the cheapest month in which you can book a flight from Santa Fe to Indianapolis (average of $175). Flying from Santa Fe to Indianapolis in December is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Anderson
Kokomo
Mooresville
Franklin
Carmel
Crawfordsville
Bloomington

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Top airline flying from Santa Fe to Indianapolis

Discover the top airline that operate flights from Santa Fe to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$254Average$444FlexibilityNo cancel feeOn-time71%

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