How long is the flight from South America to Indiana?

Airlines like Copa Airlines, Spirit Airlines, and Delta fly from South America to Indiana in about 8h 45m. The time it takes to get you to your destination can typically vary by up to 5h 40m. There are 2694 mi between South America and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from South America to Indiana one-way?

One-way options have recently been found by users for as low as $176 on Spirit Airlines. Other airlines that offer cheap prices include American Airlines from $203 and Delta from $221 one-way.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Can I find deals for flights from South America to Indiana that include hotel bookings?

Yes. In addition to deals on South America to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South America to Indiana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South America to Indiana.

Can I find deals for business class flights from South America to Indiana?

Yes. Cheapflights offers flight deals from South America to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$176+ Flights from South America to Indiana

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheap flight deals from South America to Indiana

Round-trip from	$305 (Kiwi.com)
One-way from	$176 (Cheapflightsfares)

From South America to Indiana

Search Deals

One-way flight from South America to Indiana

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Find flight deals from South America to Indiana

Cheapest flights from South America to Indiana
Explore the most affordable flight options available from South America to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Wed 12/102:17 amBOG - ORD

1 stop12h 40mMultiple Airlines

Tue 1/67:30 amORD - BOG

1 stop16h 42mMultiple Airlines

Deal found 10/29

$305

Tue 12/1612:49 amGYE - ORD

1 stop11h 19mSpirit Airlines

Tue 1/135:05 amORD - GYE

1 stop17h 40mSpirit Airlines

Deal found 10/28

$305

Fri 11/146:08 pmBOG - ORD

1 stop19h 38mCopa Airlines

Tue 11/182:07 pmORD - BOG

1 stop18h 18mCopa Airlines

Deal found 10/29

$309

Mon 12/1512:49 amGYE - ORD

1 stop11h 19mSpirit Airlines

Tue 1/138:41 amORD - GYE

1 stop14h 04mSpirit Airlines

Deal found 10/29

$309

Sat 11/223:17 pmBOG - ORD

1 stop9h 12mSpirit Airlines

Tue 11/255:00 amORD - BOG

1 stop8h 10mSpirit Airlines

Deal found 10/27

$312

Fri 11/213:17 pmBOG - ORD

1 stop19h 00mSpirit Airlines

Tue 11/255:00 amORD - BOG

1 stop8h 10mSpirit Airlines

Deal found 10/27

$313

Mon 11/103:15 pmBOG - ORD

1 stop10h 12mSpirit Airlines

Sun 11/165:10 amORD - BOG

1 stop8h 00mSpirit Airlines

Deal found 10/27

$317

Thu 11/273:14 pmMDE - ORD

1 stop8h 59mSpirit Airlines

Tue 12/210:12 amORD - MDE

1 stop13h 44mSpirit Airlines

Deal found 10/28

$318

Mon 12/152:17 amBOG - ORD

1 stop9h 56mSpirit Airlines

Tue 1/65:00 amORD - BOG

1 stop8h 09mSpirit Airlines

Deal found 10/27

$318

Mon 11/103:15 pmBOG - ORD

1 stop10h 12mSpirit Airlines

Sat 11/155:10 amORD - BOG

1 stop8h 00mSpirit Airlines

Deal found 10/27

$319

Wed 12/173:05 pmBOG - ORD

1 stop10h 04mSpirit Airlines

Tue 1/67:30 amORD - BOG

1 stop16h 42mSpirit Airlines

Deal found 10/27

$320

Sat 11/223:14 pmMDE - ORD

1 stop9h 15mSpirit Airlines

Sat 11/293:43 pmORD - MDE

1 stop8h 13mSpirit Airlines

Deal found 10/26

$321

Best flights from South America to Indiana
Discover carefully curated flight deals from South America to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2025.

Sat 11/2210:40 amBOG - ORD

1 stop14h 25mCopa Airlines

Sat 11/292:07 pmORD - BOG

1 stop19h 03mCopa Airlines

Deal found 10/29

$309

Tue 12/162:17 amBOG - ORD

1 stop9h 56mSpirit Airlines

Thu 1/13:26 pmORD - BOG

1 stop8h 46mSpirit Airlines

Deal found 10/26

$327

Wed 4/19:45 amMDE - ORD

1 stop14h 25mUnited Airlines

Thu 4/169:05 pmORD - MDE

1 stop24h 05mUnited Airlines

Deal found 10/27

$328

Sat 11/223:55 pmBOG - MDW

1 stop8h 45mDelta

Thu 11/2710:47 amMDW - BOG

1 stop7h 43mDelta

Deal found 10/29

$365

Mon 2/912:59 amGYE - ORD

1 stop21h 01mMultiple Airlines

Sat 5/22:35 pmORD - GYE

1 stop8h 45mMultiple Airlines

Deal found 10/28

$389

Fri 4/244:00 pmGYE - ORD

1 stop20h 41mLATAM Airlines

Tue 4/286:10 pmORD - GYE

1 stop13h 10mLATAM Airlines

Deal found 10/26

$391

Tue 3/103:30 amUIO - ORD

1 stop17h 50mAvianca

Tue 3/2411:20 pmORD - UIO

1 stop13h 50mAvianca

Deal found 10/28

$442

Mon 4/201:45 amGRU - ORD

1 stop13h 30mGOL

Thu 4/302:35 pmORD - GRU

1 stop32h 05mGOL

Deal found 10/27

$585

Mon 2/25:00 amMDE - ORD

1 stop8h 31mCopa Airlines

Sat 2/212:22 pmORD - MDE

1 stop16h 56mCopa Airlines

Deal found 10/27

$325

Thu 11/2710:45 amMDE - ORD

1 stop23h 26mUnited Airlines

Wed 12/319:23 pmORD - MDE

1 stop23h 42mUnited Airlines

Deal found 10/28

$328

Tue 12/1612:49 amGYE - ORD

1 stop11h 24mSpirit Airlines

Wed 1/75:00 amORD - GYE

1 stop17h 53mSpirit Airlines

Deal found 10/28

$339

Tue 4/215:00 amMDE - ORD

1 stop8h 46mCopa Airlines

Fri 5/153:13 pmORD - MDE

1 stop17h 05mCopa Airlines

Deal found 10/27

$325

Sun 12/71:15 amMDE - ORD

1 stop24h 00mUnited Airlines

Wed 6/1010:42 amORD - MDE

1 stop10h 28mUnited Airlines

Deal found 10/27

$328

Fri 11/219:00 amBOG - MDW

1 stop15h 40mDelta

Sun 11/3010:47 amMDW - BOG

1 stop7h 43mDelta

Deal found 10/29

$365

Wed 12/2412:49 amGYE - ORD

1 stop11h 25mSpirit Airlines

Wed 1/145:05 amORD - GYE

1 stop17h 40mSpirit Airlines

Deal found 10/26

$350

Fri 11/285:00 amMDE - ORD

1 stop8h 46mCopa Airlines

Thu 1/811:51 pmORD - MDE

1 stop13h 24mCopa Airlines

Deal found 10/28

$325

Sun 11/233:55 pmBOG - ORD

1 stop9h 07mDelta

Thu 11/275:23 amORD - BOG

1 stop13h 07mDelta

Deal found 10/29

$365

Wed 12/102:17 amBOG - ORD

1 stop9h 56mSpirit Airlines

Thu 1/13:26 pmORD - BOG

1 stop8h 46mSpirit Airlines

Deal found 10/27

$352

Sat 11/223:15 pmMDE - ORD

1 stop9h 50mCopa Airlines

Mon 12/12:07 pmORD - MDE

1 stop18h 44mCopa Airlines

Deal found 10/27

$325

Thu 11/203:55 pmBOG - ORD

1 stop9h 07mDelta

Sun 11/305:23 amORD - BOG

1 stop13h 07mDelta

Deal found 10/29

$365

Sun 11/912:55 amUIO - ORD

1 stop18h 57mMultiple Airlines

Sun 11/1610:20 pmORD - UIO

1 stop26h 00mMultiple Airlines

Deal found 10/29

$443

Thu 11/209:17 amMDE - ORD

1 stop15h 48mCopa Airlines

Thu 11/272:07 pmORD - MDE

1 stop7h 41mCopa Airlines

Deal found 10/28

$325

Fri 12/52:17 amBOG - ORD

1 stop18h 44mSpirit Airlines

Wed 12/315:00 amORD - BOG

1 stop8h 09mSpirit Airlines

Deal found 10/27

$365

Wed 12/243:55 pmBOG - MDW

1 stop18h 10mDelta

Thu 1/16:00 amMDW - BOG

1 stop7h 25mDelta

Deal found 10/28

$366

Wed 11/263:15 pmMDE - ORD

1 stop9h 50mCopa Airlines

Wed 12/37:33 amORD - MDE

1 stop11h 43mCopa Airlines

Deal found 10/28

$325

Wed 12/243:55 pmBOG - MDW

1 stop18h 10mDelta

Tue 12/305:05 pmMDW - BOG

2 stops22h 40mDelta

Deal found 10/28

$366

Tue 1/1311:59 pmLIM - ORD

1 stop22h 01mMultiple Airlines

Sun 1/186:11 pmORD - LIM

2 stops19h 34mMultiple Airlines

Deal found 10/28

$499

Mon 2/99:00 amBOG - MDW

1 stop9h 32mDelta

Mon 2/1610:35 amMDW - BOG

1 stop7h 55mDelta

Deal found 10/29

$367

Mon 12/2212:13 pmUIO - ORD

1 stop12h 52mCopa Airlines

Mon 12/2911:51 pmORD - UIO

1 stop12h 00mCopa Airlines

Deal found 10/29

$345

Thu 12/111:50 amLIM - ORD

2 stops17h 46mMultiple Airlines

Thu 1/154:10 pmORD - LIM

1 stop10h 20mMultiple Airlines

Deal found 10/28

$511

Last-minute flights from South America to Indiana
Discover last-minute flight deals from South America to Indiana. Data last updated October 29, 2025 and is based on user searches.

Thu 11/61:52 amMDE - ORD

1 stop10h 20mSpirit Airlines

Sat 2/710:15 amORD - MDE

2 stops13h 41mSpirit Airlines

Deal found 10/27

$324

Mon 11/103:15 pmBOG - ORD

1 stop10h 12mSpirit Airlines

Sun 11/165:10 amORD - BOG

1 stop8h 00mSpirit Airlines

Deal found 10/27

$317

Mon 11/103:15 pmBOG - ORD

1 stop10h 12mSpirit Airlines

Sat 11/155:10 amORD - BOG

1 stop8h 00mSpirit Airlines

Deal found 10/27

$319

Thu 11/204:45 amBOG - ORD

1 stop9h 01mCopa Airlines

Tue 12/27:33 amORD - BOG

1 stop8h 53mCopa Airlines

Deal found 10/28

$309

Thu 11/204:45 amBOG - ORD

1 stop9h 01mCopa Airlines

Sat 11/296:56 amORD - BOG

1 stop9h 30mCopa Airlines

Deal found 10/29

$329

Fri 11/213:17 pmBOG - ORD

1 stop19h 00mSpirit Airlines

Tue 11/255:00 amORD - BOG

1 stop8h 10mSpirit Airlines

Deal found 10/27

$313

Fri 11/213:17 pmBOG - ORD

1 stop19h 00mMultiple Airlines

Tue 2/38:41 amORD - BOG

2 stops20h 04mMultiple Airlines

Deal found 10/27

$323

Sat 11/223:17 pmBOG - ORD

1 stop9h 12mSpirit Airlines

Tue 11/255:00 amORD - BOG

1 stop8h 10mSpirit Airlines

Deal found 10/27

$312

Sat 11/223:14 pmMDE - ORD

1 stop9h 15mSpirit Airlines

Sat 11/293:43 pmORD - MDE

1 stop8h 13mSpirit Airlines

Deal found 10/26

$321

Sat 11/224:30 pmMDE - ORD

1 stop8h 35mCopa Airlines

Mon 12/17:33 amORD - MDE

1 stop14h 15mCopa Airlines

Deal found 10/28

$325

Thu 11/273:14 pmMDE - ORD

1 stop8h 59mSpirit Airlines

Tue 12/210:12 amORD - MDE

1 stop13h 44mSpirit Airlines

Deal found 10/28

$318

Thu 11/2710:45 amMDE - ORD

1 stop23h 26mUnited Airlines

Fri 1/29:23 pmORD - MDE

1 stop31h 19mUnited Airlines

Deal found 10/28

$328

One-way flights from South America to Indiana
Search for one-way flight options from South America to Indiana. Find affordable one-way fares based on user searches. Data last updated October 29, 2025.

Tue 12/92:05 amMDE - ORD

1 stop10h 08mSpirit Airlines

Deal found 10/27

$176

Mon 2/91:51 amMDE - ORD

1 stop8h 32mSpirit Airlines

Deal found 10/27

$178

Wed 12/106:04 amLIM - ORD

1 stop17h 02mVolaris

Deal found 10/27

$178

Wed 11/121:52 amMDE - ORD

1 stop10h 20mSpirit Airlines

Deal found 10/29

$179

Tue 12/1612:49 amGYE - ORD

1 stop11h 24mSpirit Airlines

Deal found 10/27

$193

Wed 12/107:00 amMDE - ORD

1 stop12h 08mAmerican Airlines

Deal found 10/27

$203

Sat 11/223:14 pmMDE - ORD

1 stop9h 15mSpirit Airlines

Deal found 10/26

$204

Fri 11/143:15 pmBOG - ORD

1 stop10h 12mSpirit Airlines

Deal found 10/28

$206

Wed 11/121:52 amMDE - ORD

2 stops11h 34mMultiple Airlines

Deal found 10/29

$209

Thu 11/133:15 pmBOG - ORD

1 stop10h 12mSpirit Airlines

Deal found 10/26

$209

Tue 2/1012:59 amGYE - ORD

1 stop21h 01mSpirit Airlines

Deal found 10/29

$209

Mon 12/1511:50 amMDE - ORD

2 stops24h 23mSpirit Airlines

Deal found 10/27

$210

Cheapflights Fare Finder

Use the filters below to find and compare flights from South America to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BogotáChicago

BOG - ORD

BOGORD

Bogotá El Dorado

Sat 11/22

10:40 am-12:05 am

1 stop14h 25m

Chicago O'Hare Intl

Sat 11/29

2:07 pm-10:10 am

1 stop19h 03m

$309

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Mon 2/2

5:00 am-12:31 pm

1 stop8h 31m

Chicago O'Hare Intl

Sat 2/21

2:22 pm-8:18 am

1 stop16h 56m

$325

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Tue 4/21

5:00 am-1:46 pm

1 stop8h 46m

Chicago O'Hare Intl

Fri 5/15

3:13 pm-8:18 am

1 stop17h 05m

$325

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Fri 11/28

5:00 am-12:46 pm

1 stop8h 46m

Chicago O'Hare Intl

Thu 1/8

11:51 pm-2:15 pm

1 stop13h 24m

$325

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Sat 11/22

3:15 pm-12:05 am

1 stop9h 50m

Chicago O'Hare Intl

Mon 12/1

2:07 pm-9:51 am

1 stop18h 44m

$325

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Thu 11/20

9:17 am-12:05 am

1 stop15h 48m

Chicago O'Hare Intl

Thu 11/27

2:07 pm-10:48 pm

1 stop7h 41m

$325

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Wed 11/26

3:15 pm-12:05 am

1 stop9h 50m

Chicago O'Hare Intl

Wed 12/3

7:33 am-8:16 pm

1 stop11h 43m

$325

BogotáChicago

BOG - ORD

BOGORD

Bogotá El Dorado

Tue 12/16

2:17 am-11:13 am

1 stop9h 56m

Chicago O'Hare Intl

Thu 1/1

3:26 pm-1:12 am

1 stop8h 46m

$327

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Wed 4/1

9:45 am-12:10 am

1 stop14h 25m

Chicago O'Hare Intl

Thu 4/16

9:05 pm-9:10 pm

1 stop24h 05m

$328

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Thu 11/27

10:45 am-9:11 am

1 stop23h 26m

Chicago O'Hare Intl

Wed 12/31

9:23 pm-10:05 pm

1 stop23h 42m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 60 results

...

Best time to book a flight from South America to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South America with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South America to Indiana

What is the cheapest month to book a flight from South America to Indiana?

Currently, February is the cheapest month in which you can book a flight from South America to Indiana (average of $297). Flying from South America to Indiana in May is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SA to IN?

When flying from South America to Indiana, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 48% versus a flight in the evening.

Reviews of airlines servicing Indiana

Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from South America to Indiana by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Delta

7.9

Good

7,994 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

LATAM Airlines

7.5

Good

1,871 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

American Airlines

7.2

Good

11,032 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Spirit Airlines

6.3

Okay

8,114 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Related info for your journey

How long is the flight from South America to Indiana?
Airlines like Copa Airlines, Spirit Airlines, and Delta fly from South America to Indiana in about 8h 45m. The time it takes to get you to your destination can typically vary by up to 5h 40m. There are 2694 mi between South America and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from South America to Indiana one-way?
One-way options have recently been found by users for as low as $176 on Spirit Airlines. Other airlines that offer cheap prices include American Airlines from $203 and Delta from $221 one-way.
Can I find deals for flights from South America to Indiana that include hotel bookings?
Yes. In addition to deals on South America to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South America to Indiana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South America to Indiana.
Can I find deals for business class flights from South America to Indiana?
Yes. Cheapflights offers flight deals from South America to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South America to Indiana?
Currently, February is the cheapest month in which you can book a flight from South America to Indiana (average of $297). Flying from South America to Indiana in May is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from South America to Indiana

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$303	Average$361	FlexibilityNo cancel fee	On-time65%
American Airlines	Cheapest$441	Average$750	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$508	Average$965	FlexibilityNo cancel fee	On-time81%
Delta	Cheapest$739	Average$1,151	FlexibilityNo cancel fee	On-timeN/A

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$176+ Cheap flights from South America to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South America to Indiana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South America to Indiana

Keep the following information in mind while searching for South America to Indiana flight deals. Data was last updated October 29, 2025.

Round-trip from

One-way from

Find flight deals from South America to Indiana

Cheapest flights from South America to IndianaExplore the most affordable flight options available from South America to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Explore the most affordable flight options available from South America to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South America to Indiana that are best for you.

Best time to book a flight from South America to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South America with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South America to Indiana

What is the cheapest month to book a flight from South America to Indiana?

What is the cheapest time of day to fly from SA to IN?

Find hourly flight availability from South America to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

Reviews of airlines servicing Indiana

Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from South America to Indiana by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from South America to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from South America to Indiana?

What are the cheapest airlines to fly from South America to Indiana one-way?

Can I find deals for flights from South America to Indiana that include hotel bookings?

How can I find direct flights from South America to Indiana?

Can I find deals for business class flights from South America to Indiana?

What is the cheapest month to book a flight from South America to Indiana?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South America to Indiana

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from South America to Indiana

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Travel Smart

Cheapest flights from South America to Indiana
Explore the most affordable flight options available from South America to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.