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$258+ Cheap flights from Panama City (PTY) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — ORD
Apr 13 — Apr 201
Mon 4/13
Mon 4/20
1 adult, Economy
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Cheap flight deals from Panama City to Illinois

Cheapest flights from Panama City to Illinois
Explore the most affordable flight options available from Panama City to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:10 am
PTY
-
ORD
2 stops26h 55m
Multiple Airlines
Thu 4/3011:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 3/9$377
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/93:10 pm
PTY
-
ORD
2 stops18h 27m
Multiple Airlines
Sun 5/1711:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 3/13$397
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:10 am
PTY
-
ORD
2 stops13h 49m
Multiple Airlines
Wed 4/2211:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 3/11$405
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:10 am
PTY
-
ORD
2 stops13h 49m
Multiple Airlines
Sun 4/1911:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 3/10$408
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:10 am
PTY
-
ORD
2 stops13h 49m
Multiple Airlines
Mon 4/2711:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 3/14$416
This Super.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/203:05 am
PTY
-
ORD
1 stop18h 15m
Avianca
Mon 4/2711:20 pm
ORD
-
PTY
1 stop14h 55m
Avianca
Deal found 3/9$418
This Mytrip deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:10 pm
PTY
-
ORD
3 stops26h 01m
Multiple Airlines
Wed 4/2911:20 pm
ORD
-
PTY
1 stop17h 40m
Multiple Airlines
Deal found 3/9$431
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:30 am
PTY
-
ORD
2 stops13h 01m
Multiple Airlines
Mon 4/1311:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 3/11$435
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:10 am
PTY
-
ORD
2 stops13h 49m
Multiple Airlines
Sun 5/1011:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 3/9$438
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/159:33 pm
PTY
-
MDW
1 stop16h 08m
Multiple Airlines
Wed 3/256:48 pm
MDW
-
PTY
1 stop13h 18m
Multiple Airlines
Deal found 3/10$540
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/189:33 pm
PTY
-
MDW
1 stop16h 08m
Multiple Airlines
Sun 3/296:00 am
MDW
-
PTY
1 stop10h 06m
Multiple Airlines
Deal found 3/10$556
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/139:33 pm
PTY
-
MDW
1 stop16h 08m
Multiple Airlines
Mon 3/236:00 am
MDW
-
PTY
1 stop13h 20m
Multiple Airlines
Deal found 3/10$560

Find flight deals from Panama City to Illinois

Keep the following information in mind while searching for Panama City to Illinois flight deals. Data was last updated March 14, 2026.

Round-trip from

$377
(Kiwi.com)

One-way from

$258
(Kiwi.com)

Popular in

March

Cheapest in

July

Average price

$625

Good round-trip deal

$574 or less

Good one-way deal

$596 or less
From Panama City Tocumen Intl to Illinois
Search Deals
One-way flight from Panama City Tocumen Intl to Illinois
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Panama City Tocumen Intl to Illinois.
Search Deals
Price to beat on a one-way flight from Panama City Tocumen Intl to Illinois.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Panama City to Illinois that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 4/23

10:10 am-11:59 pm

2 stops13h 49m

Chicago O'Hare Intl

Mon 4/27

11:20 pm-9:15 am

1 stop9h 55m

$416

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Thu 4/30

3:30 pm-8:39 am

2 stops17h 09m

Lambert-St Louis

Mon 5/4

8:30 pm-4:12 pm

2 stops19h 42m

$626

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 4/27

3:30 pm-8:25 am

2 stops16h 55m

Lambert-St Louis

Mon 5/4

6:00 am-6:37 pm

1 stop12h 37m

$634

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sat 5/16

7:55 am-10:30 pm

1 stop14h 35m

Lambert-St Louis

Wed 5/20

8:30 pm-4:12 pm

2 stops19h 42m

$634

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sat 5/16

10:00 am-11:19 pm

2 stops13h 19m

Lambert-St Louis

Tue 5/19

7:45 am-6:37 pm

2 stops10h 52m

$648
Quickest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 9/5

7:25 pm-1:02 am

Nonstop5h 37m

Chicago O'Hare Intl

Mon 9/14

8:01 am-1:22 pm

Nonstop5h 21m

$649

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 6/20

8:10 am-2:06 pm

Nonstop5h 56m

Chicago O'Hare Intl

Sat 6/27

3:21 pm-8:41 pm

Nonstop5h 20m

$649

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 7/9

8:10 am-1:57 pm

Nonstop5h 47m

Chicago O'Hare Intl

Tue 7/14

1:20 am-6:40 am

Nonstop5h 20m

$649

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 9/4

7:25 pm-1:02 am

Nonstop5h 37m

Chicago O'Hare Intl

Tue 9/15

8:01 am-1:22 pm

Nonstop5h 21m

$649

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 6/15

10:10 pm-4:00 am

Nonstop5h 50m

Chicago O'Hare Intl

Sun 6/28

8:02 am-1:22 pm

Nonstop5h 20m

$649

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 52 resultsSorted by cheapest first
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Best time to book a flight from Panama City to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Illinois

What is the cheapest month to book a flight from Panama City to Illinois?

Currently, October is the cheapest month in which you can book a flight from Panama City to Illinois (average of $243). Flying from Panama City to Illinois in May is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IL?

Find hourly flight availability from Panama City to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 14, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Illinois as you normally would.

Weekly flight availability from Panama City to Illinois

Explore weekly flight availability from Panama City to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 14, 2026.

The most flights from PTY to USIL are scheduled on a Friday (6 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).

How much does it cost to fly round-trip from Panama City to Illinois?

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated March 14, 2026.
Peruse reviews from past customers who have flown with Copa Airlines from Panama City to Illinois to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,570 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,570 reviews
Copa Airlines
7.5
Good
1,570 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Illinois?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl (PTY) is the airport most travelers will use when flying to Illinois from Panama City.

  • How long is the flight from Panama City to Illinois?

    Departing from Panama City to Illinois will take you 8h 01m. Airlines will cover a distance of 2316 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Panama City to Illinois one-way?

    The cheapest airlines for a one-way flight from Panama City to Illinois are Avianca ($175), Copa Airlines ($255), and United Airlines ($444).

  • What are the most popular routes from Panama City to Illinois?

    The most popular flight routes from Panama City to Illinois are Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway and Panama City Tocumen Intl - Lambert-St Louis.

  • What are the most reliable airlines from Panama City to Illinois?

    Before booking your flight to Illinois from Panama City, check out the most reliable airlines to get you to your destination on time: Copa Airlines (82%), United Airlines (81%), EVA Air( 78%).

  • What are the cheapest flights from Panama City to Illinois?

    On average you can expect to pay $722 for a flight from Panama City to Illinois. The cheapest flight overall is $341 while the most popular route, (Panama City Tocumen Intl - Chicago O'Hare Intl) is currently priced at $389.

  • Can I find deals for flights from Panama City to Illinois that include hotel bookings?

    Yes. In addition to deals on Panama City to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Illinois.

  • Can I find deals for business class flights from Panama City to Illinois?

    Yes. Cheapflights offers flight deals from Panama City to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Illinois?

    Currently, October is the cheapest month in which you can book a flight from Panama City to Illinois (average of $243). Flying from Panama City to Illinois in May is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to Illinois

Discover the top airline that operate flights from Panama City to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$405Average$642FlexibilityNo cancel feeOn-time70%

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