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$139+ Cheap flights from Missouri to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDT
Oct 22 — Oct 291
Wed 10/22
Wed 10/29
1 adult, Economy
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Cheap flight deals from Missouri to Harrisburg

Keep the following information in mind while searching for Missouri to Harrisburg flight deals. Data was last updated September 22, 2025.

Round-trip from

$249
(Delta)

One-way from

$139
(Delta)

Popular in

May

Cheapest in

February

Average price

$376
From Missouri to Harrisburg
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One-way flight from Missouri to Harrisburg
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Highest demand for flights based on searches. 18% potential increase in price ($83 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Missouri to Harrisburg

Cheapest flights from Missouri to Harrisburg
Explore the most affordable flight options available from Missouri to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2025.

This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:15 pmSTL - MDT
1 stop4h 53mDelta
Mon 10/276:25 pmMDT - STL
1 stop6h 16mDelta
Deal found 9/22$249
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/212:19 pmSGF - MDT
1 stop7h 54mAmerican Airlines
Wed 10/296:00 amMDT - SGF
1 stop7h 05mAmerican Airlines
Deal found 9/19$259
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:51 pmMCI - MDT
1 stop4h 09mDelta
Wed 10/226:25 pmMDT - MCI
1 stop6h 27mDelta
Deal found 9/20$259
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/234:39 pmMCI - MDT
1 stop4h 26mAmerican Airlines
Wed 10/296:00 amMDT - MCI
2 stops8h 00mAmerican Airlines
Deal found 9/20$264
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:57 pmSGF - MDT
1 stop5h 53mAmerican Airlines
Mon 12/84:46 pmMDT - SGF
1 stop5h 48mAmerican Airlines
Deal found 9/22$274
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:55 pmMCI - MDT
1 stop6h 13mDelta
Thu 10/236:10 amMDT - MCI
1 stop4h 35mDelta
Deal found 9/20$274
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:01 amSTL - MDT
1 stop3h 57mDelta
Mon 10/276:25 pmMDT - STL
1 stop6h 16mDelta
Deal found 9/22$283
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/39:19 amSTL - MDT
1 stop7h 09mDelta
Mon 10/66:25 pmMDT - STL
1 stop6h 16mDelta
Deal found 9/22$284
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:53 amMCI - MDT
1 stop6h 37mAmerican Airlines
Tue 12/306:00 pmMDT - MCI
1 stop5h 03mAmerican Airlines
Deal found 9/21$299
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/214:18 pmSGF - MDT
1 stop5h 55mAmerican Airlines
Sat 10/256:00 amMDT - SGF
1 stop4h 41mAmerican Airlines
Deal found 9/21$301
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:12 amMCI - MDT
1 stop5h 00mAmerican Airlines
Thu 1/15:00 amMDT - MCI
1 stop7h 26mAmerican Airlines
Deal found 9/21$309
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:06 pmSTL - MDT
1 stop4h 01mDelta
Sun 12/146:00 amMDT - STL
1 stop5h 41mDelta
Deal found 9/22$314

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from Missouri to Harrisburg that are best for you.

Fly from

Missouri

Fly to

Harrisburg

Route

Depart

Return

Price

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Fri 11/7

3:59 pm-11:08 pm

1 stop6h 09m

Harrisburg

Mon 11/10

7:12 pm-11:44 pm

1 stop5h 32m

$249

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Wed 10/22

5:00 am-10:14 am

1 stop4h 14m

Harrisburg

Sat 10/25

6:30 am-12:28 pm

1 stop6h 58m

$249

SpringfieldHarrisburg

SGF - MDT

SGFMDT

Springfield-Branson

Tue 10/21

2:19 pm-11:13 pm

1 stop7h 54m

Harrisburg

Wed 10/29

6:00 am-12:05 pm

1 stop7h 05m

$259

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Thu 11/20

2:49 pm-10:56 pm

1 stop7h 07m

Harrisburg

Sun 11/23

7:23 pm-11:12 pm

1 stop4h 49m

$259

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Sat 10/18

5:51 pm-11:00 pm

1 stop4h 09m

Harrisburg

Wed 10/22

6:25 pm-11:52 pm

1 stop6h 27m

$259

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Wed 12/24

5:41 pm-10:51 pm

1 stop4h 10m

Harrisburg

Thu 1/1

6:10 am-9:55 am

1 stop4h 45m

$259

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Thu 10/23

4:39 pm-10:05 pm

1 stop4h 26m

Harrisburg

Wed 10/29

8:00 am-12:54 pm

1 stop5h 54m

$259

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Thu 12/25

6:15 am-12:00 pm

1 stop4h 45m

Harrisburg

Thu 1/1

6:10 am-9:55 am

1 stop4h 45m

$259

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Wed 12/24

5:41 pm-10:51 pm

1 stop4h 10m

Harrisburg

Fri 1/2

6:10 am-9:55 am

1 stop4h 45m

$259

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Thu 12/25

5:41 pm-10:51 pm

1 stop4h 10m

Harrisburg

Wed 12/31

6:10 am-9:55 am

1 stop4h 45m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/22

Showing 1-10 of 49 results
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Best time to book a flight from Missouri to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Harrisburg

What is the cheapest month to book a flight from Missouri to Harrisburg?

Currently, August is the cheapest month in which you can book a flight from Missouri to Harrisburg (average of $347). Flying from Missouri to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Harrisburg?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from Missouri?

    Most people fly into Harrisburg (MDT) if they book a flight to Harrisburg from Missouri. Harrisburg is conveniently located just 8.5 mi from Harrisburg’s city center.

  • How long is the flight from Missouri to Harrisburg?

    Delta, United Airlines, and American Airlines can get you from Missouri to Harrisburg in just under 4h 14m. Your travel time can differ by up to 3h 40m. Missouri and Harrisburg are separated by a distance of 731 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Harrisburg one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $139. Users have also found prices from $190 and $237 on United Airlines and American Airlines, respectively.

  • What are the most popular routes from Missouri to Harrisburg?

    While some choose either Springfield-Branson - Harrisburg or Lambert-St Louis - Harrisburg, Kansas City - Harrisburg is the most popular route from Missouri to Harrisburg.

  • Can I find deals for flights from Missouri to Harrisburg that include hotel bookings?

    Yes. In addition to deals on Missouri to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Harrisburg.

  • Can I find deals for business class flights from Missouri to Harrisburg?

    Yes. Cheapflights offers flight deals from Missouri to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Harrisburg?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Harrisburg (average of $347). Flying from Missouri to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Carlisle
Mechanicsburg
Hershey
Camp Hill

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Alternative routes for Missouri to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Harrisburg

Discover the top 3 airlines that operate flights from Missouri to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$437FlexibilityNo cancel feeOn-time69%
DeltaCheapest$229Average$312FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$392FlexibilityNo cancel feeOn-time71%

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