HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Harrisburg

$135+ Cheap flights from Missouri to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDT
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Harrisburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Missouri to Harrisburg

Cheapest flights from Missouri to Harrisburg
Explore the most affordable flight options available from Missouri to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:05 pmSTL - MDT
1 stop4h 02mDelta
Sun 12/146:00 amMDT - STL
1 stop4h 50mDelta
Deal found 11/4$249
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:29 amMCI - MDT
1 stop4h 27mDelta
Sat 12/136:00 amMDT - MCI
1 stop4h 56mDelta
Deal found 11/6$259
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/69:44 amMCI - MDT
2 stops8h 03mAmerican Airlines
Sat 12/136:19 amMDT - MCI
1 stop7h 37mAmerican Airlines
Deal found 11/6$264
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:04 pmSTL - MDT
1 stop4h 49mAmerican Airlines
Sun 11/237:33 pmMDT - STL
1 stop5h 32mAmerican Airlines
Deal found 11/4$269
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:49 pmMCI - MDT
1 stop7h 07mAmerican Airlines
Thu 12/46:19 amMDT - MCI
1 stop7h 26mAmerican Airlines
Deal found 11/5$269
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:30 amSTL - MDT
1 stop6h 47mAmerican Airlines
Sun 1/45:00 amMDT - STL
1 stop4h 35mAmerican Airlines
Deal found 11/4$274
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:50 pmSTL - MDT
1 stop7h 09mAmerican Airlines
Sat 12/275:09 amMDT - STL
1 stop4h 26mAmerican Airlines
Deal found 11/6$279
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:35 pmSTL - MDT
1 stop4h 32mUnited Airlines
Sun 1/46:30 amMDT - STL
1 stop6h 57mUnited Airlines
Deal found 11/6$289
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:57 amSTL - MDT
2 stops21h 01mMultiple Airlines
Sun 1/410:56 amMDT - STL
1 stop23h 49mMultiple Airlines
Deal found 11/4$292
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:30 amSTL - MDT
1 stop6h 47mAmerican Airlines
Sun 1/47:30 amMDT - STL
1 stop7h 50mAmerican Airlines
Deal found 11/4$299
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:12 amMCI - MDT
1 stop5h 05mAmerican Airlines
Fri 1/28:02 pmMDT - MCI
1 stop4h 46mAmerican Airlines
Deal found 11/6$299
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2012:37 pmMCI - MDT
1 stop5h 21mAmerican Airlines
Fri 11/216:20 amMDT - MCI
1 stop8h 35mAmerican Airlines
Deal found 11/4$304

Cheap flight deals from Missouri to Harrisburg

Keep the following information in mind while searching for Missouri to Harrisburg flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$135
(United Airlines)

Popular in

April

Cheapest in

July

Average price

$353
Provider with most accurate pricing for Lambert-St Louis-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Harrisburg flights.
Search Deals
From Missouri to Harrisburg
Search Deals
One-way flight from Missouri to Harrisburg
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Harrisburg that are best for you.

Fly from

Missouri

Fly to

Harrisburg

Route

Depart

Return

Price

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Mon 12/22

6:35 pm-12:19 am

1 stop4h 44m

Harrisburg

Thu 12/25

6:42 am-12:31 pm

1 stop6h 49m

$249

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Fri 12/12

6:05 pm-11:07 pm

1 stop4h 02m

Harrisburg

Sun 12/14

6:00 am-10:45 am

1 stop5h 45m

$249

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Sat 12/6

6:29 am-11:56 am

1 stop4h 27m

Harrisburg

Sat 12/13

6:00 am-9:56 am

1 stop4h 56m

$259

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Wed 11/19

6:04 pm-11:53 pm

1 stop4h 49m

Harrisburg

Sun 11/23

7:33 pm-12:05 am

1 stop5h 32m

$269

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Tue 12/2

2:49 pm-10:56 pm

1 stop7h 07m

Harrisburg

Thu 12/4

6:19 am-12:45 pm

1 stop7h 26m

$269

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Mon 12/29

5:30 am-1:17 pm

1 stop6h 47m

Harrisburg

Sun 1/4

5:00 am-8:35 am

1 stop4h 35m

$274

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Tue 12/23

2:50 pm-10:59 pm

1 stop7h 09m

Harrisburg

Sat 12/27

5:09 am-8:35 am

1 stop4h 26m

$279

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Tue 12/23

2:50 pm-10:59 pm

1 stop7h 09m

Harrisburg

Sun 12/28

5:09 am-8:35 am

1 stop4h 26m

$279

SpringfieldHarrisburg

SGF - MDT

SGFMDT

Springfield-Branson

Tue 3/31

3:35 pm-11:40 pm

1 stop7h 05m

Harrisburg

Sun 4/5

6:00 am-11:14 am

1 stop6h 14m

$284

SpringfieldHarrisburg

SGF - MDT

SGFMDT

Springfield-Branson

Sat 4/4

4:00 pm-11:40 pm

1 stop6h 40m

Harrisburg

Sun 4/5

6:00 am-11:14 am

1 stop6h 14m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 45 results
1
2
3
...
5

Best time to book a flight from Missouri to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Harrisburg

What is the cheapest month to book a flight from Missouri to Harrisburg?

Currently, January is the cheapest month in which you can book a flight from Missouri to Harrisburg (average of $123). Flying from Missouri to Harrisburg in December is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Harrisburg?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from Missouri?

    Most people fly into Harrisburg (MDT) if they book a flight to Harrisburg from Missouri. Harrisburg is conveniently located just 8.5 mi from Harrisburg’s city center.

  • How long is the flight from Missouri to Harrisburg?

    American Airlines, Delta, and United Airlines can get you from Missouri to Harrisburg in just under 4h 02m. Your travel time can differ by up to 1h 15m. Missouri and Harrisburg are separated by a distance of 731 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Harrisburg one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $135. Users have also found prices from $135 and $295 on United Airlines and American Airlines, respectively.

  • What are the most popular routes from Missouri to Harrisburg?

    While some choose either Kansas City - Harrisburg or Springfield-Branson - Harrisburg, Lambert-St Louis - Harrisburg is the most popular route from Missouri to Harrisburg.

  • Can I find deals for flights from Missouri to Harrisburg that include hotel bookings?

    Yes. In addition to deals on Missouri to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Harrisburg.

  • Can I find deals for business class flights from Missouri to Harrisburg?

    Yes. Cheapflights offers flight deals from Missouri to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Harrisburg?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Harrisburg (average of $123). Flying from Missouri to Harrisburg in December is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Carlisle
Camp Hill

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Dallas/Fort Worth to John F Kennedy Intl flights
Los Angeles to Newark flights
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Newark flights
O'Hare Intl to John F Kennedy Intl flights
San Francisco to John F Kennedy Intl flights
Fort Lauderdale to Newark flights
Los Angeles to LaGuardia flights
Hobby to LaGuardia flights
San Francisco to Newark flights
Atlanta to John F Kennedy Intl flights
Atlanta to LaGuardia flights
O'Hare Intl to LaGuardia flights
Hobby to Newark flights
Fort Lauderdale to John F Kennedy Intl flights
Miami to Newark flights
Miami to John F Kennedy Intl flights
Hobby to John F Kennedy Intl flights
Fort Lauderdale to LaGuardia flights
Orlando to John F Kennedy Intl flights
Seattle to John F Kennedy Intl flights
O'Hare Intl to Newark flights
Tampa to John F Kennedy Intl flights
Dallas/Fort Worth to Dulles Intl flights
San Francisco to LaGuardia flights
Atlanta to Newark flights
Tampa to LaGuardia flights
Austin to John F Kennedy Intl flights
Raleigh to John F Kennedy Intl flights
Denver to John F Kennedy Intl flights
George Bush Intcntl to John F Kennedy Intl flights
Miami to LaGuardia flights
Charlotte to John F Kennedy Intl flights
Detroit to John F Kennedy Intl flights
Tampa to Newark flights
George Bush Intcntl to Newark flights
San Diego to John F Kennedy Intl flights
Sky Harbor Intl to John F Kennedy Intl flights
George Bush Intcntl to LaGuardia flights
Denver to LaGuardia flights
Seattle to Newark flights
Raleigh to LaGuardia flights
Austin to Newark flights
Orlando to LaGuardia flights
Minneapolis to John F Kennedy Intl flights
Orlando to Newark flights
Ontario to John F Kennedy Intl flights
Denver to Newark flights
Los Angeles to Dulles Intl flights

Top 3 airlines flying from Missouri to Harrisburg

Discover the top 3 airlines that operate flights from Missouri to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$427FlexibilityNo cancel feeOn-time69%
DeltaCheapest$229Average$329FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$403FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.