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Harrisburg

$135+ Cheap flights from Missouri to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDT
Mar 30 — Apr 61
Mon 3/30
Mon 4/6
1 adult, Economy
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Cheap flight deals from Missouri to Harrisburg

Cheapest flights from Missouri to Harrisburg
Explore the most affordable flight options available from Missouri to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 28, 2026.

This Expedia deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:59 pm
STL
-
MDT
1 stop22h 48m
Frontier
Sun 4/1210:06 pm
MDT
-
STL
1 stop10h 45m
Frontier
Deal found 2/25$160
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:51 pm
STL
-
MDT
1 stop27h 32m
Frontier
Fri 4/310:06 pm
MDT
-
STL
1 stop10h 45m
Frontier
Deal found 2/25$241
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:32 am
STL
-
MDT
1 stop6h 25m
American Airlines
Wed 9/167:40 pm
MDT
-
STL
1 stop4h 58m
American Airlines
Deal found 2/26$251
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:00 am
STL
-
MDT
1 stop5h 51m
United Airlines
Sun 4/266:15 am
MDT
-
STL
1 stop5h 30m
United Airlines
Deal found 2/27$260
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:15 pm
MCI
-
MDT
1 stop6h 50m
United Airlines
Sun 3/296:15 am
MDT
-
MCI
1 stop5h 12m
United Airlines
Deal found 2/24$264
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:37 am
STL
-
MDT
1 stop6h 13m
American Airlines
Sat 3/77:35 pm
MDT
-
STL
1 stop4h 17m
American Airlines
Deal found 2/24$269
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:42 pm
MCI
-
MDT
1 stop4h 08m
Delta
Fri 4/36:32 pm
MDT
-
MCI
1 stop6h 40m
Delta
Deal found 2/27$269
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:15 pm
SGF
-
MDT
1 stop5h 20m
American Airlines
Tue 4/75:38 am
MDT
-
SGF
1 stop5h 13m
American Airlines
Deal found 2/28$271
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:45 am
MCI
-
MDT
1 stop5h 34m
American Airlines
Mon 3/305:06 pm
MDT
-
MCI
2 stops8h 06m
American Airlines
Deal found 2/24$274
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/283:13 pm
SGF
-
MDT
1 stop4h 52m
United Airlines
Sat 4/410:42 am
MDT
-
SGF
1 stop7h 42m
United Airlines
Deal found 2/28$275
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:19 am
SGF
-
MDT
1 stop5h 04m
American Airlines
Sun 4/125:38 am
MDT
-
SGF
1 stop5h 13m
American Airlines
Deal found 2/27$279
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:51 pm
STL
-
MDT
1 stop27h 32m
Frontier
Sun 3/2210:13 pm
MDT
-
STL
1 stop26h 06m
Frontier
Deal found 2/24$281

Find flight deals from Missouri to Harrisburg

Keep the following information in mind while searching for Missouri to Harrisburg flight deals. Data was last updated February 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$160
(Expedia)

One-way from

$135
(American Airlines)

Popular in

August

Cheapest in

April

Average price

$318
Provider with most accurate pricing for Lambert-St Louis-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Harrisburg flights.
Search Deals
From Missouri to Harrisburg
Search Deals
One-way flight from Missouri to Harrisburg
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from Missouri to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Tue 4/21

9:10 am-4:51 pm

1 stop6h 41m

Harrisburg

Sun 4/26

6:15 am-10:45 am

1 stop5h 30m

$260

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Tue 4/21

5:51 am-11:23 am

1 stop4h 32m

Harrisburg

Sun 4/26

6:43 pm-11:46 pm

1 stop6h 03m

$260

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Sat 3/7

5:01 pm-11:27 pm

1 stop5h 26m

Harrisburg

Mon 3/9

6:32 pm-11:58 pm

1 stop6h 26m

$269

St. LouisHarrisburg

STL - MDT

STLMDT

Lambert-St Louis

Thu 4/30

6:29 am-2:18 pm

1 stop6h 49m

Harrisburg

Sun 5/3

6:43 pm-11:46 pm

1 stop6h 03m

$269

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Tue 3/31

5:42 pm-10:50 pm

1 stop4h 08m

Harrisburg

Fri 4/3

4:37 pm-8:50 pm

1 stop5h 13m

$269

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Thu 3/26

6:00 am-4:44 pm

2 stops9h 44m

Harrisburg

Tue 3/31

6:15 am-10:27 am

1 stop5h 12m

$270

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Wed 4/1

6:15 am-1:55 pm

2 stops6h 40m

Harrisburg

Sat 4/4

8:29 am-2:33 pm

1 stop7h 04m

$274

Kansas CityHarrisburg

MCI - MDT

MCIMDT

Kansas City

Sun 3/29

5:00 am-12:19 pm

1 stop6h 19m

Harrisburg

Mon 3/30

5:06 pm-12:12 am

2 stops8h 06m

$274

SpringfieldHarrisburg

SGF - MDT

SGFMDT

Springfield-Branson

Thu 4/9

5:19 am-11:23 am

1 stop5h 04m

Harrisburg

Sun 4/12

5:38 am-9:51 am

1 stop5h 13m

$279

SpringfieldHarrisburg

SGF - MDT

SGFMDT

Springfield-Branson

Sat 3/28

3:13 pm-11:13 pm

2 stops7h 00m

Harrisburg

Sat 4/4

8:29 am-2:35 pm

1 stop7h 06m

$295

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/24

Showing 1-10 of 39 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Harrisburg

What is the cheapest month to book a flight from Missouri to Harrisburg?

Currently, September is the cheapest month in which you can book a flight from Missouri to Harrisburg (average of $129). Flying from Missouri to Harrisburg in January is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Harrisburg?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from Missouri?

    Most people fly into Harrisburg (MDT) if they book a flight to Harrisburg from Missouri. Harrisburg is conveniently located just 8.5 mi from Harrisburg’s city center.

  • How long is the flight from Missouri to Harrisburg?

    United Airlines, American Airlines, and Delta can get you from Missouri to Harrisburg in just under 4h 32m. Your travel time can differ by up to 2h 09m. Missouri and Harrisburg are separated by a distance of 731 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Harrisburg?

    While some choose either Springfield-Branson - Harrisburg or Lambert-St Louis - Harrisburg, Kansas City - Harrisburg is the most popular route from Missouri to Harrisburg.

  • Can I find deals for flights from Missouri to Harrisburg that include hotel bookings?

    Yes. In addition to deals on Missouri to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Harrisburg.

  • Can I find deals for business class flights from Missouri to Harrisburg?

    Yes. Cheapflights offers flight deals from Missouri to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Harrisburg?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Harrisburg (average of $129). Flying from Missouri to Harrisburg in January is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Hershey
Mechanicsburg
Camp Hill
Carlisle

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Alternative routes for Missouri to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Harrisburg

Discover the top 3 airlines that operate flights from Missouri to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$219Average$368FlexibilityNo cancel feeOn-time71%
DeltaCheapest$229Average$323FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$251Average$446FlexibilityNo cancel feeOn-time69%

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