$195+ Cheap flights from St. Louis to Harrisburg (STL - MDT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDT
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Harrisburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Harrisburg
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Cheapest flights from St. Louis to HarrisburgExplore the most affordable flight options available from St. Louis to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from St. Louis to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 am -
1 stop5h 19m
Tue 10/138:09 pm -
1 stop5h 10m
Deal found 9/8![American Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:00 am -
1 stop5h 17m
Mon 10/128:09 pm -
1 stop5h 10m
Deal found 9/7![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:00 am -
1 stop5h 23m
Mon 9/286:54 pm -
1 stop6h 33m
Deal found 9/7![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:45 pm -
1 stop4h 26m
Mon 10/56:08 am -
1 stop5h 42m
Deal found 9/11![American Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:05 pm -
1 stop3h 53m
Sun 10/116:13 am -
1 stop4h 36m
Deal found 9/9![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:00 am -
1 stop5h 19m
Mon 10/126:08 am -
1 stop5h 42m
Deal found 9/9![American Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:45 pm -
1 stop4h 26m
Mon 10/56:08 am -
1 stop7h 27m
Deal found 9/9![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:30 am -
1 stop6h 40m
Mon 9/286:54 pm -
1 stop6h 33m
Deal found 9/9![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:00 am -
1 stop5h 23m
Wed 9/165:45 am -
1 stop5h 44m
Deal found 9/8![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:25 pm -
1 stop6h 36m
Sun 9/206:00 am -
1 stop5h 18m
Deal found 9/10![American Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
1 stop5h 23m
Sun 10/45:45 am -
1 stop5h 44m
Deal found 9/12![American Airlines logo]()
$409
Best flights from St. Louis to HarrisburgDiscover carefully curated flight deals from St. Louis to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from St. Louis to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:00 am -
1 stop5h 19m
Mon 10/126:08 am -
1 stop5h 42m
Deal found 9/11![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:35 am -
1 stop4h 17m
Wed 9/305:54 pm -
1 stop6h 05m
Deal found 9/11![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
1 stop5h 23m
Sun 10/45:45 am -
1 stop5h 44m
Deal found 9/12![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/61:09 pm -
1 stop4h 56m
Sat 1/96:30 am -
1 stop5h 00m
Deal found 9/11![United Airlines logo]()
$455
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:35 am -
2 stops25h 24m
Sun 10/46:25 am -
1 stop6h 50m
Deal found 9/9![United Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:35 am -
1 stop4h 17m
Mon 9/285:54 pm -
1 stop6h 05m
Deal found 9/9![United Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:24 am -
1 stop7h 01m
Sun 11/297:05 pm -
1 stop5h 51m
Deal found 9/7![American Airlines logo]()
$739
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:12 pm -
2 stops21h 47m
Mon 10/125:54 pm -
1 stop6h 05m
Deal found 9/10![United Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
2 stops6h 59m
Mon 9/285:54 pm -
1 stop4h 27m
Deal found 9/7![United Airlines logo]()
$742
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:29 pm -
1 stop7h 03m
Tue 9/296:30 am -
3 stops28h 11m
Deal found 9/8![United Airlines logo]()
$743
Last-minute flights from St. Louis to HarrisburgDiscover last-minute flight deals from St. Louis to Harrisburg. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Harrisburg. Data last updated September 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:18 pm -
1 stop5h 35m
Sat 9/196:00 am -
1 stop5h 18m
Deal found 9/9![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:25 pm -
1 stop6h 36m
Sun 9/206:00 am -
1 stop5h 18m
Deal found 9/10![American Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:30 am -
1 stop6h 40m
Mon 9/286:54 pm -
1 stop6h 33m
Deal found 9/9![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:00 am -
1 stop5h 23m
Mon 9/286:54 pm -
1 stop6h 33m
Deal found 9/7![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:45 pm -
1 stop4h 26m
Mon 10/56:08 am -
1 stop5h 42m
Deal found 9/11![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:45 pm -
1 stop4h 26m
Mon 10/56:08 am -
1 stop7h 27m
Deal found 9/9![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
1 stop5h 23m
Sun 10/45:45 am -
1 stop5h 44m
Deal found 9/12![American Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:00 am -
1 stop5h 17m
Mon 10/128:09 pm -
1 stop5h 10m
Deal found 9/7![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 am -
1 stop5h 19m
Tue 10/138:09 pm -
1 stop5h 10m
Deal found 9/8![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:05 pm -
1 stop3h 53m
Sun 10/116:13 am -
1 stop4h 36m
Deal found 9/9![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:00 am -
1 stop5h 19m
Mon 10/126:08 am -
1 stop5h 42m
Deal found 9/9![American Airlines logo]()
$386
One-way flights from St. Louis to HarrisburgSearch for one-way flight options from St. Louis to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from St. Louis to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:35 pm -
2 stops21h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$195
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/221:08 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:45 pm -
1 stop4h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
3 stops45h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$396
This Alaska Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:36 pm -
2 stops14h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Alaska Airlines logo]()
$636
Find flight deals from St. Louis to Harrisburg
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $310 (American Airlines) |
One-way from | $195 (Kiwi.com) |
Popular in | September |
Cheapest in | April |
Average price | $701 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from St. Louis to Harrisburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Fri 10/16
6:35 pm-5:25 pm
2 stops21h 50m
Harrisburg
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
Quickest round-trip
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Sun 11/22
1:08 pm-9:33 pm
1 stop7h 25m
Harrisburg
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$274
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Fri 10/9
5:00 am-11:19 am
1 stop5h 19m
Harrisburg
Mon 10/12
6:08 am-10:50 am
1 stop5h 42m
$409
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Fri 10/2
5:00 am-11:23 am
1 stop5h 23m
Harrisburg
Sun 10/4
5:45 am-10:29 am
1 stop5h 44m
$409
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Sat 9/26
11:35 am-4:52 pm
1 stop4h 17m
Harrisburg
Wed 9/30
5:54 pm-10:59 pm
1 stop6h 05m
$449
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Wed 1/6
1:09 pm-7:05 pm
1 stop4h 56m
Harrisburg
Sat 1/9
6:30 am-10:30 am
1 stop5h 00m
$455
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Fri 10/2
11:35 am-1:59 pm
2 stops25h 24m
Harrisburg
Sun 10/4
6:25 am-12:15 pm
1 stop6h 50m
$546
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Thu 9/24
11:35 am-4:52 pm
1 stop4h 17m
Harrisburg
Mon 9/28
5:54 pm-10:59 pm
1 stop6h 05m
$553
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Fri 9/25
7:36 pm-11:23 am
2 stops14h 47m
Harrisburg
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$636
St. LouisHarrisburg
STL Lambert-St Louis - MDT Harrisburg
STLMDT
Lambert-St Louis
Fri 10/9
3:12 pm-1:59 pm
2 stops21h 47m
Harrisburg
Mon 10/12
5:54 pm-10:59 pm
1 stop6h 05m
$719
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Harrisburg
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Harrisburg in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Harrisburg flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Harrisburg
Have a flexible travel schedule? Discover the best time to fly to Harrisburg from St. Louis with our price prediction graph.
STL-MDT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Harrisburg
Prices
More
What’s the top layover airport for flights from St. Louis to Harrisburg?
Share of 1-stop round-trip flights from St. Louis to Harrisburg chosen by Cheapflights users in the past 12 months, using the same layover each way.
Detroit (DTW) – chosen by Cheapflights users on 67% of 1-stop itineraries from St. Louis to Harrisburg on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Harrisburg?
Average round-trip fare for 1-stop flights from St. Louis to Harrisburg, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Detroit (DTW) is the most affordable 1-stop option, with an average round-trip price of $265.
What’s the fastest layover option from St. Louis to Harrisburg?
Shortest average travel time for 1-stop one-way flights from St. Louis to Harrisburg, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Detroit (DTW) have the shortest average one-way travel time for 1-stop routes: 4h 17m.
Which airport typically offers the quickest layover for flights from St. Louis to Harrisburg?
Average layover duration for 1-stop one-way flights from St. Louis to Harrisburg, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Detroit (DTW) offer the fastest connection on this route, with an average layover time of 1h 12m.
Reviews of airlines servicing Harrisburg
Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated September 12, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from St. Louis to Harrisburg have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Harrisburg?
Book flights to Harrisburg if you plan to visit one of these locationsHershey
Mechanicsburg
Camp Hill
Carlisle
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St. Louis and Harrisburg flights
Browse other St. Louis and Harrisburg flight options. Last updated on September 12, 2026.
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Top 3 airlines flying from St. Louis to Harrisburg
Discover the top 3 airlines that operate flights from St. Louis to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$344 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$370 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$281 | Average$362 | FlexibilityNo cancel fee | On-time69% |