$124+ Cheap flights from Missouri to Greenville (GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Greenville
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Cheapest flights from Missouri to GreenvilleExplore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:05 am
STL
- GSP
1 stop4h 00m
Delta
Tue 6/238:52 am
GSP
- STL
1 stop4h 42m
Delta
Deal found 4/28![Delta logo]()
$247
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Tue 6/212:50 pm
GSP
- STL
2 stops8h 10m
Southwest
Deal found 4/28![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:19 am
STL
- GSP
1 stop6h 34m
Delta
Sat 5/305:40 am
GSP
- STL
1 stop4h 08m
Delta
Deal found 4/30![Delta logo]()
$266
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:21 am
STL
- GSP
1 stop4h 30m
Delta
Sat 6/275:44 am
GSP
- STL
1 stop4h 24m
Delta
Deal found 4/29![Delta logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:19 pm
STL
- GSP
1 stop14h 14m
Multiple Airlines
Fri 5/294:10 pm
GSP
- STL
1 stop8h 47m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$276
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Sat 5/308:00 am
GSP
- STL
2 stops6h 35m
Southwest
Deal found 4/30![Southwest logo]()
$277
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:15 am
STL
- GSP
1 stop7h 08m
American Airlines
Sat 5/305:25 pm
GSP
- STL
1 stop7h 33m
American Airlines
Deal found 4/28![American Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:16 pm
MCI
- GSP
1 stop5h 01m
United Airlines
Wed 6/36:00 am
GSP
- MCI
1 stop5h 29m
United Airlines
Deal found 4/29![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:45 pm
STL
- GSP
2 stops6h 55m
Southwest
Mon 6/86:50 pm
GSP
- STL
1 stop4h 55m
Southwest
Deal found 4/30![Southwest logo]()
$296
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:36 pm
MCI
- GSP
1 stop7h 02m
Delta
Tue 9/225:45 am
GSP
- MCI
1 stop6h 17m
Delta
Deal found 4/30![Delta logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:57 pm
MCI
- GSP
1 stop18h 28m
Allegiant Air
Thu 7/303:46 pm
GSP
- MCI
1 stop19h 04m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/710:35 am
MCI
- GSP
1 stop20h 04m
Multiple Airlines
Fri 6/129:43 pm
GSP
- MCI
2 stops20h 38m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$305
Best flights from Missouri to GreenvilleDiscover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
STL
- GSP
1 stop5h 05m
Delta
Tue 6/235:44 am
GSP
- STL
1 stop3h 32m
Delta
Deal found 4/26![Delta logo]()
$247
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Tue 6/212:50 pm
GSP
- STL
2 stops8h 10m
Southwest
Deal found 4/28![Southwest logo]()
$252
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:18 pm
STL
- GSP
1 stop6h 59m
United Airlines
Wed 8/196:30 am
GSP
- STL
1 stop7h 19m
United Airlines
Deal found 4/30![United Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:27 am
STL
- GSP
1 stop3h 47m
American Airlines
Sun 9/136:00 am
GSP
- STL
1 stop5h 40m
American Airlines
Deal found 4/30![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:19 am
STL
- GSP
1 stop6h 34m
Delta
Sat 5/305:40 am
GSP
- STL
1 stop4h 08m
Delta
Deal found 4/30![Delta logo]()
$266
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:45 pm
STL
- GSP
2 stops6h 55m
Southwest
Sat 5/308:00 am
GSP
- STL
2 stops6h 35m
Southwest
Deal found 4/30![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:49 pm
SGF
- GSP
1 stop3h 54m
Delta
Thu 6/45:40 am
GSP
- SGF
1 stop6h 47m
Delta
Deal found 4/29![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:05 am
MCI
- GSP
1 stop6h 05m
Southwest
Wed 6/36:45 am
GSP
- MCI
2 stops8h 50m
Southwest
Deal found 4/29![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:52 pm
MCI
- GSP
1 stop6h 01m
United Airlines
Wed 8/126:30 am
GSP
- MCI
1 stop4h 51m
United Airlines
Deal found 4/29![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:00 pm
MCI
- GSP
1 stop5h 59m
United Airlines
Wed 8/197:00 am
GSP
- MCI
2 stops11h 34m
United Airlines
Deal found 4/30![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:30 pm
MCI
- GSP
1 stop6h 30m
Southwest
Sun 6/287:30 pm
GSP
- MCI
1 stop5h 40m
Southwest
Deal found 4/30![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
STL
- GSP
2 stops7h 20m
United Airlines
Wed 6/106:30 am
GSP
- STL
2 stops10h 16m
United Airlines
Deal found 4/26![United Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:52 pm
SGF
- GSP
1 stop3h 51m
Delta
Mon 5/185:40 am
GSP
- SGF
1 stop6h 47m
Delta
Deal found 4/29![Delta logo]()
$384
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:10 pm
MCI
- GSP
1 stop3h 40m
Southwest
Wed 6/247:50 pm
GSP
- MCI
1 stop4h 35m
Southwest
Deal found 4/30![Southwest logo]()
$375
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:05 pm
SGF
- GSP
1 stop5h 48m
United Airlines
Wed 8/267:00 am
GSP
- SGF
2 stops8h 33m
United Airlines
Deal found 4/28![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:35 pm
STL
- GSP
1 stop4h 10m
Southwest
Mon 7/136:50 pm
GSP
- STL
1 stop6h 15m
Southwest
Deal found 4/29![Southwest logo]()
$387
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:00 am
SGF
- GSP
2 stops7h 11m
American Airlines
Fri 5/225:25 pm
GSP
- SGF
1 stop7h 19m
American Airlines
Deal found 4/26![American Airlines logo]()
$827
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:35 pm
SGF
- GSP
2 stops14h 20m
United Airlines
Thu 6/46:30 am
GSP
- SGF
2 stops13h 38m
United Airlines
Deal found 4/29![United Airlines logo]()
$826
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:50 pm
SGF
- GSP
2 stops16h 08m
United Airlines
Mon 5/187:35 pm
GSP
- SGF
2 stops27h 57m
United Airlines
Deal found 4/29![United Airlines logo]()
$943
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:00 pm
SGF
- GSP
2 stops17h 58m
United Airlines
Fri 5/227:40 pm
GSP
- SGF
2 stops21h 30m
United Airlines
Deal found 4/26![United Airlines logo]()
$978
Last-minute flights from Missouri to GreenvilleDiscover last-minute flight deals from Missouri to Greenville. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Greenville. Data last updated May 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:15 am
STL
- GSP
1 stop7h 08m
American Airlines
Sat 5/305:25 pm
GSP
- STL
1 stop7h 33m
American Airlines
Deal found 4/28![American Airlines logo]()
$285
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/251:45 pm
STL
- GSP
2 stops7h 50m
Southwest
Sat 5/3012:25 pm
GSP
- STL
1 stop5h 00m
Southwest
Deal found 4/28![Southwest logo]()
$323
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Tue 6/25:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Deal found 4/28![Southwest logo]()
$247
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:19 am
STL
- GSP
1 stop6h 34m
Delta
Sat 5/305:40 am
GSP
- STL
1 stop4h 08m
Delta
Deal found 4/30![Delta logo]()
$266
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Sat 5/308:00 am
GSP
- STL
2 stops6h 35m
Southwest
Deal found 4/30![Southwest logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:19 pm
STL
- GSP
1 stop14h 14m
Multiple Airlines
Fri 5/294:10 pm
GSP
- STL
1 stop8h 47m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$276
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:16 pm
MCI
- GSP
1 stop5h 01m
United Airlines
Wed 6/36:00 am
GSP
- MCI
1 stop5h 29m
United Airlines
Deal found 4/29![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:05 am
MCI
- GSP
1 stop6h 05m
Southwest
Wed 6/36:45 am
GSP
- MCI
2 stops8h 50m
Southwest
Deal found 4/29![Southwest logo]()
$322
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:40 pm
STL
- GSP
2 stops8h 00m
Southwest
Fri 5/2912:35 pm
GSP
- STL
2 stops7h 20m
Southwest
Deal found 4/29![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:49 pm
SGF
- GSP
1 stop3h 54m
Delta
Thu 6/45:40 am
GSP
- SGF
1 stop6h 47m
Delta
Deal found 4/29![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:15 pm
MCI
- GSP
1 stop4h 20m
Southwest
Thu 6/46:50 pm
GSP
- MCI
1 stop6h 20m
Southwest
Deal found 4/30![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:35 am
MCI
- GSP
1 stop5h 48m
American Airlines
Mon 6/17:32 pm
GSP
- MCI
1 stop4h 25m
American Airlines
Deal found 4/28![American Airlines logo]()
$332
One-way flights from Missouri to GreenvilleSearch for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:15 am
STL
- GSP
1 stop7h 30m
American Airlines
Deal found 4/28![American Airlines logo]()
$124
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:40 am
STL
- GSP
2 stops6h 30m
Southwest
Deal found 4/28![Southwest logo]()
$129
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:21 am
STL
- GSP
1 stop3h 52m
Delta
Deal found 4/28![Delta logo]()
$143
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
STL
- GSP
2 stops7h 19m
United Airlines
Deal found 4/28![United Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:08 pm
STL
- GSP
3 stops40h 06m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:27 pm
STL
- GSP
2 stops37h 06m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$175
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:30 am
MCI
- GSP
1 stop6h 37m
American Airlines
Deal found 4/27![American Airlines logo]()
$177
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:00 am
MCI
- GSP
1 stop6h 01m
Delta
Deal found 4/28![Delta logo]()
$179
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:03 am
STL
- GSP
1 stop8h 32m
American Airlines
Deal found 4/28![American Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:53 am
SGF
- GSP
1 stop28h 52m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$192
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:12 pm
STL
- GSP
1 stop3h 47m
Delta
Deal found 4/29![Delta logo]()
$194
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:05 pm
STL
- GSP
2 stops7h 15m
Southwest
Deal found 4/29![Southwest logo]()
$199
Find flight deals from Missouri to Greenville
Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $247 (Delta) |
One-way from | $124 (American Airlines) |
Popular in | February |
Cheapest in | August |
Average price | $378 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Wed 6/3
6:00 am-12:05 pm
1 stop5h 05m
Greenville
Tue 6/23
5:44 am-8:16 am
1 stop3h 32m
$247
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 5/26
2:30 pm-9:40 pm
1 stop6h 10m
Greenville
Tue 6/2
12:50 pm-8:00 pm
2 stops8h 10m
$252
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 5/26
10:19 am-5:53 pm
1 stop6h 34m
Greenville
Sat 5/30
5:40 am-8:48 am
1 stop4h 08m
$266
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 5/26
1:45 pm-9:40 pm
2 stops6h 55m
Greenville
Sat 5/30
8:00 am-1:35 pm
2 stops6h 35m
$307
SpringfieldGreenville
SGF - GSP
SGFGSP
Springfield-Branson
Thu 5/28
6:49 pm-11:43 pm
1 stop3h 54m
Greenville
Thu 6/4
5:40 am-11:27 am
1 stop6h 47m
$309
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Wed 5/27
6:05 am-1:10 pm
1 stop6h 05m
Greenville
Wed 6/3
6:45 am-2:35 pm
2 stops8h 50m
$322
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 8/18
1:18 pm-9:17 pm
1 stop6h 59m
Greenville
Wed 8/19
6:30 am-12:49 pm
1 stop7h 19m
$327
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Wed 9/9
5:27 am-10:14 am
1 stop3h 47m
Greenville
Sun 9/13
6:00 am-10:40 am
1 stop5h 40m
$347
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Wed 6/24
2:30 pm-10:00 pm
1 stop6h 30m
Greenville
Sun 6/28
7:30 pm-12:10 am
1 stop5h 40m
$347
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Tue 8/11
2:52 pm-9:53 pm
1 stop6h 01m
Greenville
Wed 8/12
6:30 am-10:21 am
1 stop4h 51m
$367
Showing 1-10 of 44 resultsSorted by cheapest first
Best time to book a flight from Missouri to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
STL-GSP
MCI-GSP
SGF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Greenville
USMO-GSP
STL-GSP
MCI-GSP
SGF-GSP
What is the cheapest month to book a flight from Missouri to Greenville?
Currently, October is the cheapest month in which you can book a flight from Missouri to Greenville (average of $167). Flying from Missouri to Greenville in March is currently the most expensive (average of $346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Greenville?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Greenville
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Complete your trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 1, 2026.
Missouri and Greenville flights
Browse other Missouri and Greenville flight options. Last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Greenville flights
Consider these flights traveling from Missouri to Greenville.
Top 3 airlines flying from Missouri to Greenville
Discover the top 3 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$172 | Average$417 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$354 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$412 | FlexibilityNo cancel fee | On-time63% |