$130+ Cheap flights from Missouri to Greenville (GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Greenville
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Cheapest flights from Missouri to GreenvilleExplore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:20 pm -
1 stop5h 45m
Tue 11/37:02 am -
1 stop4h 45m
Deal found 9/3![American Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:23 am -
1 stop4h 44m
Tue 11/106:42 pm -
1 stop6h 42m
Deal found 9/3![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:10 am -
1 stop4h 15m
Tue 11/37:05 am -
2 stops7h 00m
Deal found 9/3![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
2 stops6h 10m
Tue 11/106:45 pm -
1 stop4h 40m
Deal found 9/3![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:35 pm -
1 stop4h 16m
Tue 10/135:40 am -
1 stop6h 11m
Deal found 9/2![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:49 pm -
1 stop6h 04m
Mon 10/126:43 pm -
1 stop6h 36m
Deal found 9/2![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:30 pm -
1 stop4h 30m
Tue 10/201:25 pm -
2 stops6h 35m
Deal found 9/2![Southwest logo]()
$284
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:50 pm -
2 stops7h 05m
Wed 9/308:15 am -
2 stops7h 55m
Deal found 9/2![Southwest logo]()
$298
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:50 pm -
1 stop4h 00m
Thu 10/86:25 am -
2 stops8h 55m
Deal found 9/3![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:31 pm -
1 stop4h 20m
Mon 10/125:40 am -
1 stop4h 49m
Deal found 9/2![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:25 am -
2 stops7h 10m
Tue 11/37:05 am -
2 stops7h 40m
Deal found 9/3![Southwest logo]()
$313
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:05 am -
2 stops8h 30m
Mon 10/128:40 pm -
1 stop4h 00m
Deal found 9/2![Southwest logo]()
$324
Best flights from Missouri to GreenvilleDiscover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:20 pm -
1 stop5h 45m
Tue 11/37:02 am -
1 stop4h 45m
Deal found 9/3![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:30 pm -
1 stop4h 30m
Thu 10/88:40 pm -
1 stop4h 00m
Deal found 9/3![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:18 pm -
1 stop5h 35m
Sat 12/55:40 am -
1 stop6h 57m
Deal found 9/3![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/611:25 am -
1 stop4h 29m
Wed 2/106:30 am -
1 stop4h 59m
Deal found 9/2![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:50 pm -
2 stops7h 05m
Wed 9/305:30 pm -
1 stop5h 45m
Deal found 9/2![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:49 pm -
1 stop6h 04m
Mon 10/126:43 pm -
1 stop6h 36m
Deal found 9/2![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:15 am -
2 stops8h 40m
Mon 9/286:55 pm -
1 stop4h 15m
Deal found 9/2![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/42:24 pm -
1 stop6h 39m
Tue 2/96:37 pm -
1 stop5h 04m
Deal found 9/4![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:08 pm -
1 stop6h 50m
Fri 10/306:20 am -
1 stop6h 50m
Deal found 9/3![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:25 am -
2 stops7h 10m
Tue 11/37:05 am -
2 stops7h 40m
Deal found 9/3![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:04 am -
1 stop4h 56m
Sun 10/255:40 am -
1 stop4h 49m
Deal found 9/6![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:05 am -
2 stops8h 30m
Mon 10/128:40 pm -
1 stop4h 00m
Deal found 9/2![Southwest logo]()
$324
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/911:19 am -
2 stops11h 00m
Wed 1/135:31 pm -
1 stop7h 01m
Deal found 9/3![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:25 pm -
1 stop4h 25m
Mon 10/56:25 pm -
1 stop4h 21m
Deal found 9/3![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:20 am -
2 stops8h 25m
Mon 12/76:45 pm -
1 stop4h 10m
Deal found 9/5![Southwest logo]()
$352
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/411:19 am -
2 stops11h 00m
Tue 2/95:31 pm -
1 stop7h 01m
Deal found 9/4![United Airlines logo]()
$449
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:00 pm -
2 stops7h 55m
Sat 11/148:25 am -
1 stop6h 55m
Deal found 9/6![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 pm -
1 stop3h 45m
Mon 10/58:40 pm -
1 stop4h 15m
Deal found 9/5![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:10 pm -
2 stops7h 40m
Mon 11/26:40 am -
1 stop4h 15m
Deal found 9/5![Southwest logo]()
$378
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:20 pm -
2 stops8h 00m
Tue 12/2912:45 pm -
2 stops9h 20m
Deal found 9/4![Southwest logo]()
$433
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:55 pm -
1 stop6h 15m
Sun 11/86:40 am -
2 stops8h 25m
Deal found 9/2![Southwest logo]()
$446
Last-minute flights from Missouri to GreenvilleDiscover last-minute flight deals from Missouri to Greenville. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Greenville. Data last updated September 7, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:50 pm -
2 stops7h 05m
Wed 9/308:15 am -
2 stops7h 55m
Deal found 9/2![Southwest logo]()
$298
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:50 pm -
1 stop4h 00m
Thu 10/86:25 am -
2 stops8h 55m
Deal found 9/3![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:35 pm -
1 stop4h 16m
Tue 10/135:40 am -
1 stop6h 11m
Deal found 9/2![Delta logo]()
$277
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:31 pm -
1 stop4h 20m
Mon 10/125:40 am -
1 stop4h 49m
Deal found 9/2![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:30 pm -
1 stop4h 30m
Tue 10/138:30 am -
2 stops7h 30m
Deal found 9/2![Southwest logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:01 am -
1 stop7h 34m
Mon 10/128:33 pm -
1 stop4h 25m
Deal found 9/2![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:49 pm -
1 stop6h 04m
Mon 10/126:43 pm -
1 stop6h 36m
Deal found 9/2![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:05 am -
2 stops8h 30m
Mon 10/128:40 pm -
1 stop4h 00m
Deal found 9/2![Southwest logo]()
$324
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:30 pm -
1 stop4h 30m
Tue 10/201:25 pm -
2 stops6h 35m
Deal found 9/2![Southwest logo]()
$284
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:25 am -
2 stops7h 10m
Tue 11/37:05 am -
2 stops7h 40m
Deal found 9/3![Southwest logo]()
$313
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:20 pm -
1 stop5h 45m
Tue 11/37:02 am -
1 stop4h 45m
Deal found 9/3![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:10 am -
1 stop4h 15m
Tue 11/37:05 am -
2 stops7h 00m
Deal found 9/3![Southwest logo]()
$264
One-way flights from Missouri to GreenvilleSearch for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:44 am -
1 stop6h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am -
2 stops9h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Southwest logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm -
3 stops41h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$138
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:31 pm -
1 stop4h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$187
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:55 pm -
2 stops7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Southwest logo]()
$192
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:50 pm -
1 stop3h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Southwest logo]()
$193
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/302:55 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Southwest logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:06 am -
3 stops29h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:32 pm -
3 stops35h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:32 pm -
3 stops36h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:40 pm -
1 stop3h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Southwest logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:29 pm -
3 stops42h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$353
Find flight deals from Missouri to Greenville
Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (Southwest) |
One-way from | $130 (American Airlines) |
Popular in | February |
Cheapest in | September |
Average price | $293 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityGreenville
MCI Kansas City - GSP Greenville
MCIGSP
Kansas City
Tue 11/10
8:00 am-6:10 pm
2 stops9h 10m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$135
Kansas CityGreenville
MCI Kansas City - GSP Greenville
MCIGSP
Kansas City
Tue 10/6
5:31 pm-10:51 pm
1 stop4h 20m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$187
Kansas CityGreenville
MCI Kansas City - GSP Greenville
MCIGSP
Kansas City
Tue 10/6
12:55 pm-9:05 pm
2 stops7h 10m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$192
St. LouisGreenville
STL Lambert-St Louis - GSP Greenville
STLGSP
Lambert-St Louis
Fri 10/2
5:50 pm-10:45 pm
1 stop3h 55m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$193
St. LouisGreenville
STL Lambert-St Louis - GSP Greenville
STLGSP
Lambert-St Louis
Sat 10/31
3:20 pm-10:05 pm
1 stop5h 45m
Greenville
Tue 11/3
7:02 am-10:47 am
1 stop4h 45m
$259
St. LouisGreenville
STL Lambert-St Louis - GSP Greenville
STLGSP
Lambert-St Louis
Mon 10/5
2:30 pm-8:00 pm
1 stop4h 30m
Greenville
Thu 10/8
8:40 pm-11:40 pm
1 stop4h 00m
$259
Kansas CityGreenville
MCI Kansas City - GSP Greenville
MCIGSP
Kansas City
Mon 11/30
1:55 pm-9:40 pm
2 stops6h 45m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$264
St. LouisGreenville
STL Lambert-St Louis - GSP Greenville
STLGSP
Lambert-St Louis
Tue 9/29
12:50 pm-8:55 pm
2 stops7h 05m
Greenville
Wed 9/30
5:30 pm-10:15 pm
1 stop5h 45m
$264
St. LouisGreenville
STL Lambert-St Louis - GSP Greenville
STLGSP
Lambert-St Louis
Sat 9/26
5:15 am-2:55 pm
2 stops8h 40m
Greenville
Mon 9/28
6:55 pm-10:10 pm
1 stop4h 15m
$264
St. LouisGreenville
STL Lambert-St Louis - GSP Greenville
STLGSP
Lambert-St Louis
Sat 10/10
12:49 pm-7:53 pm
1 stop6h 04m
Greenville
Mon 10/12
6:43 pm-12:19 am
1 stop6h 36m
$279
Showing 1-10 of 33 resultsSorted by cheapest first
Best time to book a flight from Missouri to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
MCI-GSP
STL-GSP
SGF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Greenville
USMO-GSP
MCI-GSP
STL-GSP
SGF-GSP
What is the cheapest month to book a flight from Missouri to Greenville?
Currently, September is the cheapest month in which you can book a flight from Missouri to Greenville (average of $293). Flying from Missouri to Greenville in May is currently the most expensive (average of $527). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Greenville
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Complete your trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Missouri and Greenville flights
Browse other Missouri and Greenville flight options. Last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Greenville flights
Consider these flights traveling from Missouri to Greenville.
Top 4 airlines flying from Missouri to Greenville
Discover the top 4 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$430 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$356 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$265 | Average$489 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$287 | Average$383 | FlexibilityNo cancel fee | On-time69% |