$125+ Cheap flights from Missouri to Greenville (GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — GSP
Jul 17 — Jul 241
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Greenville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to GreenvilleExplore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:32 am
STL
- GSP
1 stop6h 37m
American Airlines
Tue 7/217:32 pm
GSP
- STL
1 stop5h 26m
American Airlines
Deal found 6/16![American Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:40 am
STL
- GSP
2 stops6h 30m
Southwest
Tue 7/211:50 pm
GSP
- STL
1 stop6h 25m
Southwest
Deal found 6/16![Southwest logo]()
$254
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:15 am
STL
- GSP
2 stops9h 05m
Southwest
Wed 7/227:00 am
GSP
- STL
2 stops8h 50m
Southwest
Deal found 6/15![Southwest logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:16 pm
MCI
- GSP
2 stops36h 19m
Multiple Airlines
Thu 7/93:46 pm
GSP
- MCI
1 stop19h 04m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:19 pm
STL
- GSP
1 stop5h 40m
American Airlines
Sat 8/86:45 am
GSP
- STL
1 stop7h 10m
American Airlines
Deal found 6/16![American Airlines logo]()
$293
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:53 pm
STL
- GSP
1 stop5h 41m
United Airlines
Sat 7/186:10 am
GSP
- STL
1 stop7h 01m
United Airlines
Deal found 6/13![United Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:08 pm
SGF
- GSP
1 stop6h 51m
Delta
Sat 7/45:16 pm
GSP
- SGF
1 stop4h 57m
Delta
Deal found 6/16![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:31 am
MCI
- GSP
1 stop6h 38m
American Airlines
Tue 7/215:28 pm
GSP
- MCI
1 stop5h 29m
American Airlines
Deal found 6/16![American Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:55 am
STL
- GSP
1 stop5h 15m
Southwest
Sun 7/197:30 pm
GSP
- STL
1 stop5h 25m
Southwest
Deal found 6/12![Southwest logo]()
$318
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:29 am
MCI
- GSP
1 stop6h 55m
American Airlines
Tue 7/77:20 pm
GSP
- MCI
1 stop5h 59m
American Airlines
Deal found 6/16![American Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:30 pm
MCI
- GSP
2 stops6h 35m
Southwest
Tue 7/217:00 am
GSP
- MCI
2 stops8h 45m
Southwest
Deal found 6/16![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
STL
- GSP
1 stop4h 32m
United Airlines
Wed 8/266:30 am
GSP
- STL
1 stop6h 32m
United Airlines
Deal found 6/13![United Airlines logo]()
$329
Best flights from Missouri to GreenvilleDiscover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
Discover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:32 am
STL
- GSP
1 stop6h 37m
American Airlines
Tue 7/217:32 pm
GSP
- STL
1 stop5h 26m
American Airlines
Deal found 6/16![American Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:40 am
STL
- GSP
2 stops6h 30m
Southwest
Tue 7/211:50 pm
GSP
- STL
1 stop6h 25m
Southwest
Deal found 6/16![Southwest logo]()
$254
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:53 pm
STL
- GSP
1 stop5h 41m
United Airlines
Sat 7/186:10 am
GSP
- STL
1 stop7h 01m
United Airlines
Deal found 6/13![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:55 am
STL
- GSP
1 stop5h 15m
Southwest
Sun 7/197:30 pm
GSP
- STL
1 stop5h 25m
Southwest
Deal found 6/12![Southwest logo]()
$318
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
STL
- GSP
1 stop4h 32m
United Airlines
Wed 8/2611:25 am
GSP
- STL
2 stops11h 35m
United Airlines
Deal found 6/12![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:00 am
MCI
- GSP
2 stops7h 05m
American Airlines
Mon 8/316:34 pm
GSP
- MCI
1 stop7h 01m
American Airlines
Deal found 6/14![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/252:30 pm
STL
- GSP
1 stop5h 50m
Southwest
Sat 8/86:45 am
GSP
- STL
2 stops7h 30m
Southwest
Deal found 6/16![Southwest logo]()
$338
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:10 am
STL
- GSP
1 stop7h 10m
Southwest
Mon 7/277:05 am
GSP
- STL
2 stops6h 40m
Southwest
Deal found 6/13![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
STL
- GSP
2 stops12h 04m
United Airlines
Tue 7/215:43 pm
GSP
- STL
1 stop4h 43m
United Airlines
Deal found 6/16![United Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:23 am
SGF
- GSP
1 stop4h 39m
United Airlines
Sat 8/296:30 am
GSP
- SGF
1 stop5h 18m
United Airlines
Deal found 6/16![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/182:15 pm
MCI
- GSP
2 stops7h 40m
Southwest
Wed 7/221:50 pm
GSP
- MCI
1 stop7h 50m
Southwest
Deal found 6/16![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:00 am
MCI
- GSP
1 stop6h 02m
United Airlines
Wed 8/266:30 am
GSP
- MCI
1 stop6h 50m
United Airlines
Deal found 6/16![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:40 pm
STL
- GSP
2 stops8h 00m
Southwest
Thu 7/1612:55 pm
GSP
- STL
2 stops7h 15m
Southwest
Deal found 6/12![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:10 pm
MCI
- GSP
2 stops7h 45m
Southwest
Mon 7/206:50 pm
GSP
- MCI
1 stop6h 25m
Southwest
Deal found 6/14![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:15 pm
MCI
- GSP
2 stops7h 40m
Southwest
Sat 7/188:40 pm
GSP
- MCI
1 stop3h 50m
Southwest
Deal found 6/13![Southwest logo]()
$422
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:10 pm
MCI
- GSP
1 stop3h 45m
Southwest
Mon 7/208:30 am
GSP
- MCI
2 stops9h 10m
Southwest
Deal found 6/13![Southwest logo]()
$422
Last-minute flights from Missouri to GreenvilleDiscover last-minute flight deals from Missouri to Greenville. Data last updated June 17, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Greenville. Data last updated June 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:29 am
MCI
- GSP
1 stop6h 55m
American Airlines
Tue 7/77:20 pm
GSP
- MCI
1 stop5h 59m
American Airlines
Deal found 6/16![American Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:16 pm
MCI
- GSP
2 stops36h 19m
Multiple Airlines
Thu 7/93:46 pm
GSP
- MCI
1 stop19h 04m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:08 pm
SGF
- GSP
1 stop6h 51m
Delta
Sat 7/45:16 pm
GSP
- SGF
1 stop4h 57m
Delta
Deal found 6/16![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:07 pm
SGF
- GSP
1 stop5h 19m
United Airlines
Sat 7/410:30 am
GSP
- SGF
2 stops8h 23m
United Airlines
Deal found 6/16![United Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:53 pm
STL
- GSP
1 stop5h 41m
United Airlines
Sat 7/186:10 am
GSP
- STL
1 stop7h 01m
United Airlines
Deal found 6/13![United Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:32 am
STL
- GSP
1 stop6h 37m
American Airlines
Tue 7/217:32 pm
GSP
- STL
1 stop5h 26m
American Airlines
Deal found 6/16![American Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:40 am
STL
- GSP
2 stops6h 30m
Southwest
Tue 7/211:50 pm
GSP
- STL
1 stop6h 25m
Southwest
Deal found 6/16![Southwest logo]()
$254
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:31 am
MCI
- GSP
1 stop6h 38m
American Airlines
Tue 7/215:28 pm
GSP
- MCI
1 stop5h 29m
American Airlines
Deal found 6/16![American Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:30 pm
MCI
- GSP
2 stops6h 35m
Southwest
Tue 7/217:00 am
GSP
- MCI
2 stops8h 45m
Southwest
Deal found 6/16![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:15 am
STL
- GSP
2 stops9h 05m
Southwest
Wed 7/227:00 am
GSP
- STL
2 stops8h 50m
Southwest
Deal found 6/15![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:55 am
STL
- GSP
1 stop5h 15m
Southwest
Sun 7/197:30 pm
GSP
- STL
1 stop5h 25m
Southwest
Deal found 6/12![Southwest logo]()
$318
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:19 pm
STL
- GSP
1 stop5h 40m
American Airlines
Sat 8/86:45 am
GSP
- STL
1 stop7h 10m
American Airlines
Deal found 6/16![American Airlines logo]()
$293
One-way flights from Missouri to GreenvilleSearch for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
Search for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:45 pm
STL
- GSP
1 stop3h 10m
Southwest
Deal found 6/12![Southwest logo]()
$125
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
STL
- GSP
2 stops7h 20m
United Airlines
Deal found 6/12![United Airlines logo]()
$130
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:24 am
STL
- GSP
1 stop5h 43m
Delta
Deal found 6/12![Delta logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:33 pm
STL
- GSP
2 stops20h 32m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$139
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:00 am
STL
- GSP
1 stop3h 30m
Southwest
Deal found 6/13![Southwest logo]()
$145
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:00 am
STL
- GSP
1 stop5h 01m
Delta
Deal found 6/12![Delta logo]()
$149
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:15 am
STL
- GSP
2 stops8h 40m
Southwest
Deal found 6/15![Southwest logo]()
$150
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:04 pm
MCI
- GSP
1 stop5h 47m
American Airlines
Deal found 6/16![American Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:23 pm
SGF
- GSP
1 stop12h 06m
Allegiant Air
Deal found 6/16![Allegiant Air logo]()
$161
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
STL
- GSP
2 stops7h 20m
United Airlines
Deal found 6/12![United Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:31 pm
STL
- GSP
2 stops36h 26m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:55 am
STL
- GSP
1 stop5h 15m
Southwest
Deal found 6/16![Southwest logo]()
$198
Find flight deals from Missouri to Greenville
Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated June 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (American Airlines) |
One-way from | $125 (Southwest) |
Popular in | January |
Cheapest in | October |
Average price | $364 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 7/14
5:32 am-1:09 pm
1 stop6h 37m
Greenville
Tue 7/21
7:32 pm-11:58 pm
1 stop5h 26m
$249
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 7/14
5:40 am-1:10 pm
2 stops6h 30m
Greenville
Tue 7/21
1:50 pm-7:15 pm
1 stop6h 25m
$254
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Sat 7/11
4:53 pm-11:34 pm
1 stop5h 41m
Greenville
Sat 7/18
6:10 am-12:11 pm
1 stop7h 01m
$297
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Wed 7/15
6:55 am-1:10 pm
1 stop5h 15m
Greenville
Sun 7/19
7:30 pm-11:55 pm
1 stop5h 25m
$318
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 8/25
8:00 am-1:32 pm
1 stop4h 32m
Greenville
Wed 8/26
11:25 am-10:00 pm
2 stops11h 35m
$334
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Sat 7/25
2:30 pm-9:20 pm
1 stop5h 50m
Greenville
Sat 8/8
6:45 am-1:15 pm
2 stops7h 30m
$338
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Sat 7/25
5:10 am-1:20 pm
1 stop7h 10m
Greenville
Mon 7/27
7:05 am-12:45 pm
2 stops6h 40m
$347
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Sat 7/18
2:15 pm-10:55 pm
2 stops7h 40m
Greenville
Wed 7/22
1:50 pm-8:40 pm
1 stop7h 50m
$367
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Sat 8/29
5:00 am-1:05 pm
2 stops7h 05m
Greenville
Mon 8/31
6:34 pm-12:35 am
1 stop7h 01m
$369
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 7/14
6:00 am-7:04 pm
2 stops12h 04m
Greenville
Tue 7/21
5:43 pm-9:26 pm
1 stop4h 43m
$382
Showing 1-10 of 40 resultsSorted by cheapest first
Best time to book a flight from Missouri to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
STL-GSP
MCI-GSP
SGF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Greenville
USMO-GSP
STL-GSP
MCI-GSP
SGF-GSP
What is the cheapest month to book a flight from Missouri to Greenville?
Currently, August is the cheapest month in which you can book a flight from Missouri to Greenville (average of $172). Flying from Missouri to Greenville in July is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Greenville?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
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Alternative routes for Missouri to Greenville
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Complete your trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 17, 2026.
Missouri and Greenville flights
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Popular flight searches
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Missouri to Greenville flights
Consider these flights traveling from Missouri to Greenville.
Top 3 airlines flying from Missouri to Greenville
Discover the top 3 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$354 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$480 | FlexibilityNo cancel fee | On-time63% |