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Greenville

$91+ Cheap flights from Missouri to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — GSP
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/193:00 pmSGF - GSP
1 stop5h 57mUnited Airlines
Mon 12/228:34 amGSP - SGF
1 stop7h 04mUnited Airlines
Deal found 12/14$391
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:04 amMCI - GSP
1 stop5h 24mAmerican Airlines
Mon 1/57:00 amGSP - MCI
1 stop5h 26mAmerican Airlines
Deal found 12/14$443
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:15 pmMCI - GSP
1 stop23h 20mMultiple Airlines
Thu 1/111:33 amGSP - MCI
1 stop12h 26mMultiple Airlines
Deal found 12/13$453
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:05 pmSTL - GSP
2 stops5h 50mSouthwest
Sun 1/44:20 pmGSP - STL
1 stop8h 15mSouthwest
Deal found 12/13$487
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:05 pmSTL - GSP
2 stops5h 50mSouthwest
Sat 1/36:15 pmGSP - STL
1 stop7h 00mSouthwest
Deal found 12/13$493
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amMCI - GSP
2 stops7h 15mUnited Airlines
Mon 1/52:50 pmGSP - MCI
1 stop6h 41mUnited Airlines
Deal found 12/14$512
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:15 amSGF - GSP
2 stops50h 11mMultiple Airlines
Mon 12/2210:04 pmGSP - SGF
1 stop11h 08mMultiple Airlines
Deal found 12/14$515
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:35 amMCI - GSP
1 stop4h 44mAmerican Airlines
Sun 12/286:00 amGSP - MCI
1 stop6h 24mAmerican Airlines
Deal found 12/13$559
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:00 amSTL - GSP
1 stop4h 11mAmerican Airlines
Sun 12/289:02 amGSP - STL
1 stop5h 12mAmerican Airlines
Deal found 12/13$561
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:05 pmSTL - GSP
2 stops5h 50mSouthwest
Sun 12/287:40 amGSP - STL
2 stops11h 15mSouthwest
Deal found 12/13$569
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:10 pmSTL - GSP
1 stop4h 37mUnited Airlines
Fri 1/25:36 pmGSP - STL
1 stop6h 07mUnited Airlines
Deal found 12/14$607
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:40 amMCI - GSP
2 stops29h 35mUnited Airlines
Sun 12/285:36 pmGSP - MCI
1 stop5h 14mUnited Airlines
Deal found 12/13$609

Find flight deals from Missouri to Greenville

Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$91
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$386
Provider with most accurate pricing for Lambert-St Louis-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Greenville flights.
Search Deals
From Missouri to Greenville
Search Deals
One-way flight from Missouri to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Missouri

Fly to

Greenville

Route

Depart

Return

Price

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Fri 1/30

5:00 pm-11:59 pm

1 stop5h 59m

Greenville

Sun 2/1

6:25 am-12:14 pm

1 stop6h 49m

$269

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Tue 1/6

5:00 pm-11:59 pm

1 stop5h 59m

Greenville

Tue 1/13

8:09 am-12:15 pm

1 stop5h 06m

$269

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Sun 1/11

5:00 pm-11:55 pm

1 stop5h 55m

Greenville

Sun 1/18

8:22 am-12:11 pm

1 stop4h 49m

$289

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Wed 2/18

2:00 pm-7:50 pm

1 stop4h 50m

Greenville

Wed 2/25

11:15 am-7:50 pm

2 stops9h 35m

$298

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Sun 1/11

12:26 pm-11:26 pm

2 stops10h 00m

Greenville

Sun 1/18

4:40 pm-9:19 pm

1 stop5h 39m

$299

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Thu 1/29

10:58 am-7:07 pm

1 stop7h 09m

Greenville

Mon 2/2

4:40 pm-11:12 pm

1 stop7h 32m

$321

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Sat 5/2

4:17 pm-9:28 pm

1 stop4h 11m

Greenville

Sun 5/3

7:25 am-10:41 am

1 stop4h 16m

$365

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 1/3

7:02 pm-11:32 pm

1 stop3h 30m

Greenville

Tue 1/6

8:22 am-11:05 am

1 stop3h 43m

$372

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 1/3

7:30 am-11:45 am

1 stop3h 15m

Greenville

Tue 1/6

10:05 am-7:05 pm

2 stops10h 00m

$377

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Sat 2/14

3:08 pm-9:59 pm

1 stop5h 51m

Greenville

Wed 2/18

6:30 am-4:25 pm

2 stops10h 55m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 35 results
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Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Greenville

What is the cheapest month to book a flight from Missouri to Greenville?

Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $135). Flying from Missouri to Greenville in March is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to GSP?

Find hourly flight availability from Missouri to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 15% on flights from Missouri to Greenville by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Missouri?

    Most people fly into Greenville (GSP) if they book a flight to Greenville from Missouri. Greenville is conveniently located just 10.4 mi from Greenville’s city center.

  • How long is the flight from Missouri to Greenville?

    Airlines like American Airlines, Delta, and Southwest fly from Missouri to Greenville in about 4h 50m. The time it takes to get you to your destination can typically vary by up to 1h 09m. Airlines will cover a distance of 752 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Greenville?

    The most popular flight routes from Missouri to Greenville are Kansas City - Greenville, Springfield-Branson - Greenville and Lambert-St Louis - Greenville.

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $135). Flying from Missouri to Greenville in March is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Alternative routes for Missouri to Greenville

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Top 2 airlines flying from Missouri to Greenville

Discover the top 2 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$384FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$414FlexibilityNo cancel feeOn-time71%

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