HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$143+ Cheap flights from Missouri to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/83:30 pmSTL - GSP
1 stop24h 18mMultiple Airlines
lun. 12/158:03 pmGSP - STL
1 stop27h 30mMultiple Airlines
Deal found 10/30$227
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/112:47 pmSTL - GSP
1 stop22h 23mMultiple Airlines
dom. 12/144:00 pmGSP - STL
1 stop17h 59mMultiple Airlines
Deal found 10/29$238
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/1310:35 amMCI - GSP
1 stop27h 30mMultiple Airlines
lun. 11/178:03 pmGSP - MCI
1 stop17h 25mMultiple Airlines
Deal found 10/28$264
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/129:25 amSGF - GSP
1 stop4h 56mAmerican Airlines
sáb. 11/1512:47 pmGSP - SGF
1 stop6h 16mAmerican Airlines
Deal found 10/30$279
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/35:12 pmMCI - GSP
1 stop5h 28mDelta
jue. 12/45:35 amGSP - MCI
1 stop4h 54mDelta
Deal found 10/28$287
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/33:33 pmMCI - GSP
2 stops6h 31mAmerican Airlines
jue. 12/46:50 amGSP - MCI
1 stop6h 11mAmerican Airlines
Deal found 10/28$292
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/266:00 pmSGF - GSP
1 stop4h 55mAmerican Airlines
mié. 12/312:17 pmGSP - SGF
1 stop5h 48mAmerican Airlines
Deal found 10/28$294
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/48:20 pmSGF - GSP
1 stop23h 29mAllegiant Air
lun. 12/159:39 pmGSP - SGF
1 stop20h 30mAllegiant Air
Deal found 10/30$300
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/87:00 amSTL - GSP
2 stops8h 05mSouthwest
lun. 12/153:05 pmGSP - STL
2 stops7h 30mSouthwest
Deal found 10/30$307
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/264:02 pmSGF - GSP
1 stop4h 23mDelta
sáb. 12/66:40 amGSP - SGF
1 stop5h 10mDelta
Deal found 10/30$318
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/263:05 pmSGF - GSP
1 stop5h 54mUnited Airlines
mié. 12/36:00 amGSP - SGF
2 stops9h 44mUnited Airlines
Deal found 10/28$337
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:05 amSTL - GSP
2 stops9h 00mSouthwest
dom. 12/148:00 amGSP - STL
2 stops9h 40mSouthwest
Deal found 10/29$342

Cheap flight deals from Missouri to Greenville

Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$227
(Kiwi.com)

One-way from

$143
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$297
Provider with most accurate pricing for Lambert-St Louis-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Greenville flights.
Search Deals
From Missouri to Greenville
Search Deals
One-way flight from Missouri to Greenville
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Missouri

Fly to

Greenville

Route

Depart

Return

Price

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

lun. 12/8

3:30 pm-4:48 pm

1 stop24h 18m

Greenville

lun. 12/15

8:03 pm-10:33 pm

1 stop27h 30m

$227

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

jue. 12/11

2:47 pm-2:10 pm

1 stop22h 23m

Greenville

dom. 12/14

4:00 pm-8:59 am

1 stop17h 59m

$238

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

jue. 11/13

10:35 am-3:05 pm

1 stop27h 30m

Greenville

lun. 11/17

8:03 pm-12:28 pm

1 stop17h 25m

$264

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

sáb. 2/28

6:00 am-1:09 pm

1 stop6h 09m

Greenville

mié. 3/4

5:45 am-11:14 am

1 stop6h 29m

$274

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

mié. 11/12

9:25 am-3:21 pm

1 stop4h 56m

Greenville

sáb. 11/15

12:47 pm-6:03 pm

1 stop6h 16m

$279

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

jue. 11/13

4:28 pm-11:58 pm

1 stop6h 30m

Greenville

lun. 11/17

4:24 pm-8:47 pm

1 stop5h 23m

$279

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

mié. 12/3

5:12 pm-11:40 pm

1 stop5h 28m

Greenville

jue. 12/4

5:35 am-9:29 am

1 stop4h 54m

$287

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

mié. 12/3

3:33 pm-11:04 pm

2 stops6h 31m

Greenville

jue. 12/4

6:50 am-12:01 pm

1 stop6h 11m

$292

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

sáb. 2/28

4:47 pm-11:54 pm

1 stop6h 07m

Greenville

mié. 3/4

4:25 pm-9:13 pm

1 stop5h 48m

$293

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

jue. 12/4

8:20 pm-8:49 pm

1 stop23h 29m

Greenville

lun. 12/15

9:39 pm-5:09 pm

1 stop20h 30m

$300

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 46 results
1
2
3
...
5

Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Greenville

What is the cheapest month to book a flight from Missouri to Greenville?

Currently, February is the cheapest month in which you can book a flight from Missouri to Greenville (average of $153). Flying from Missouri to Greenville in June is currently the most expensive (average of $237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to GSP?

Find hourly flight availability from Missouri to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 15% on flights from Missouri to Greenville by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Missouri?

    Most people fly into Greenville (GSP) if they book a flight to Greenville from Missouri. Greenville is conveniently located just 10.4 mi from Greenville’s city center.

  • How long is the flight from Missouri to Greenville?

    Airlines like Delta, American Airlines, and Southwest fly from Missouri to Greenville in about 4h 56m. The time it takes to get you to your destination can typically vary by up to 3h 09m. Airlines will cover a distance of 644 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Greenville?

    The most popular flight routes from Missouri to Greenville are Kansas City - Greenville, Lambert-St Louis - Greenville and Springfield-Branson - Greenville.

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Greenville (average of $153). Flying from Missouri to Greenville in June is currently the most expensive (average of $237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
Newark to Charlotte flights
LaGuardia to Charlotte flights
Boston to Charlotte flights
LaGuardia to Charleston flights
John F Kennedy Intl to Charleston flights
Boston to Charleston flights
Denver to Charlotte flights
Newark to Charleston flights
O'Hare Intl to Charlotte flights
John F Kennedy Intl to Savannah flights
Dallas/Fort Worth to Charlotte flights
Dulles Intl to Charlotte flights
O'Hare Intl to Charleston flights
Newark to Savannah flights
Baltimore to Charlotte flights
Philadelphia to Charlotte flights
LaGuardia to Savannah flights
Newark to Myrtle Beach flights
Hobby to Charlotte flights
Boston to Savannah flights
O'Hare Intl to Savannah flights
Newark to Greenville flights
Minneapolis to Charlotte flights
Dulles Intl to Charleston flights
John F Kennedy Intl to Myrtle Beach flights
LaGuardia to Myrtle Beach flights
George Bush Intcntl to Charlotte flights
Baltimore to Charleston flights
Los Angeles to Charlotte flights
Providence to Charleston flights
Orlando to Charlotte flights
White Plains to Charleston flights
LaGuardia to Greenville flights
John F Kennedy Intl to Greenville flights
Philadelphia to Charleston flights
Love Field to Charlotte flights
Reagan-National to Charleston flights
Minneapolis to Charleston flights
Denver to Charleston flights
San Francisco to Charlotte flights
LaGuardia to Columbia flights
Seattle to Charlotte flights
Fort Lauderdale to Charlotte flights
Dulles Intl to Savannah flights
Denver to Savannah flights
Philadelphia to Savannah flights
Miami to Charlotte flights
Dallas/Fort Worth to Charleston flights
Detroit to Charlotte flights

Top 2 airlines flying from Missouri to Greenville

Discover the top 2 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$394FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$414FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.