$150+ Cheap flights from Missouri to Greenville (GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Apr 16 — Apr 231
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Greenville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to GreenvilleExplore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:05 pm
MCI
- GSP
1 stop6h 42m
United Airlines
Tue 4/216:30 am
GSP
- MCI
1 stop4h 57m
United Airlines
Deal found 3/12![United Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:28 am
MCI
- GSP
1 stop4h 33m
American Airlines
Thu 4/95:12 pm
GSP
- MCI
1 stop7h 55m
American Airlines
Deal found 3/12![American Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:30 pm
MCI
- GSP
2 stops6h 10m
Southwest
Tue 4/215:05 pm
GSP
- MCI
2 stops6h 25m
Southwest
Deal found 3/12![Southwest logo]()
$297
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:30 am
STL
- GSP
1 stop4h 24m
United Airlines
Wed 4/296:30 am
GSP
- STL
1 stop6h 52m
United Airlines
Deal found 3/12![United Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:19 pm
STL
- GSP
1 stop15h 24m
Multiple Airlines
Thu 5/143:28 pm
GSP
- STL
2 stops42h 27m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:45 pm
STL
- GSP
2 stops6h 55m
Southwest
Wed 4/295:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Deal found 3/12![Southwest logo]()
$308
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:42 pm
STL
- GSP
1 stop5h 37m
American Airlines
Sat 4/1811:31 am
GSP
- STL
1 stop6h 10m
American Airlines
Deal found 3/13![American Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:35 am
STL
- GSP
1 stop3h 25m
Southwest
Wed 4/298:20 am
GSP
- STL
1 stop7h 55m
Southwest
Deal found 3/12![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Sat 4/1810:45 am
GSP
- STL
2 stops8h 25m
Southwest
Deal found 3/13![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:55 pm
SGF
- GSP
1 stop3h 59m
Delta
Sat 4/115:40 am
GSP
- SGF
1 stop6h 27m
Delta
Deal found 3/15![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Tue 4/215:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Deal found 3/15![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:20 pm
MCI
- GSP
2 stops5h 55m
Southwest
Mon 5/186:25 pm
GSP
- MCI
1 stop6h 10m
Southwest
Deal found 3/15![Southwest logo]()
$354
Best flights from Missouri to GreenvilleDiscover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
Discover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:05 pm
MCI
- GSP
1 stop6h 42m
United Airlines
Tue 4/216:30 am
GSP
- MCI
1 stop4h 57m
United Airlines
Deal found 3/12![United Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:33 pm
MCI
- GSP
2 stops7h 29m
American Airlines
Thu 4/95:12 pm
GSP
- MCI
1 stop7h 55m
American Airlines
Deal found 3/12![American Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:35 am
STL
- GSP
1 stop3h 25m
Southwest
Wed 4/298:20 am
GSP
- STL
1 stop7h 55m
Southwest
Deal found 3/12![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:45 pm
SGF
- GSP
1 stop3h 53m
Delta
Sat 8/155:05 pm
GSP
- SGF
1 stop6h 24m
Delta
Deal found 3/14![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:40 pm
MCI
- GSP
2 stops7h 00m
Southwest
Thu 5/286:25 pm
GSP
- MCI
1 stop6h 10m
Southwest
Deal found 3/13![Southwest logo]()
$326
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:56 pm
SGF
- GSP
1 stop4h 56m
Delta
Wed 4/155:42 am
GSP
- SGF
1 stop6h 19m
Delta
Deal found 3/15![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:45 am
STL
- GSP
1 stop5h 25m
United Airlines
Tue 5/56:27 pm
GSP
- STL
1 stop6h 30m
United Airlines
Deal found 3/11![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:20 pm
MCI
- GSP
2 stops5h 55m
Southwest
Mon 5/186:25 pm
GSP
- MCI
1 stop6h 10m
Southwest
Deal found 3/15![Southwest logo]()
$354
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:12 pm
SGF
- GSP
1 stop4h 40m
American Airlines
Tue 6/236:41 pm
GSP
- SGF
1 stop4h 59m
American Airlines
Deal found 3/12![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:55 am
MCI
- GSP
1 stop5h 57m
United Airlines
Wed 4/86:30 am
GSP
- MCI
1 stop4h 57m
United Airlines
Deal found 3/12![United Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:30 pm
SGF
- GSP
1 stop3h 46m
Delta
Mon 8/175:05 pm
GSP
- SGF
1 stop6h 24m
Delta
Deal found 3/13![Delta logo]()
$414
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:25 pm
STL
- GSP
2 stops6h 10m
Southwest
Thu 5/1412:35 pm
GSP
- STL
2 stops12h 20m
Southwest
Deal found 3/13![Southwest logo]()
$378
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:26 pm
MCI
- GSP
1 stop5h 04m
American Airlines
Sun 5/175:20 am
GSP
- MCI
1 stop4h 41m
American Airlines
Deal found 3/13![American Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:55 am
MCI
- GSP
2 stops8h 04m
United Airlines
Thu 4/96:30 am
GSP
- MCI
2 stops11h 14m
United Airlines
Deal found 3/12![United Airlines logo]()
$410
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:56 pm
SGF
- GSP
1 stop4h 56m
Delta
Sun 4/125:40 am
GSP
- SGF
1 stop6h 27m
Delta
Deal found 3/13![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:25 am
MCI
- GSP
1 stop6h 25m
Southwest
Sun 5/245:55 pm
GSP
- MCI
1 stop6h 10m
Southwest
Deal found 3/16![Southwest logo]()
$427
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:15 am
SGF
- GSP
2 stops11h 44m
United Airlines
Mon 8/174:15 pm
GSP
- SGF
1 stop8h 27m
United Airlines
Deal found 3/13![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:38 pm
MCI
- GSP
1 stop4h 05m
Delta
Sun 5/1010:09 am
GSP
- MCI
1 stop6h 59m
Delta
Deal found 3/12![Delta logo]()
$441
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:55 pm
SGF
- GSP
1 stop3h 59m
Delta
Sun 4/125:40 am
GSP
- SGF
1 stop6h 27m
Delta
Deal found 3/15![Delta logo]()
$464
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SGF
- GSP
2 stops12h 04m
United Airlines
Thu 5/286:00 am
GSP
- SGF
1 stop5h 42m
United Airlines
Deal found 3/12![United Airlines logo]()
$542
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:56 pm
SGF
- GSP
1 stop4h 56m
Delta
Thu 4/165:42 am
GSP
- SGF
1 stop6h 19m
Delta
Deal found 3/15![Delta logo]()
$549
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:55 pm
SGF
- GSP
1 stop13h 48m
United Airlines
Sat 8/156:30 am
GSP
- SGF
2 stops10h 51m
United Airlines
Deal found 3/14![United Airlines logo]()
$557
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:55 pm
SGF
- GSP
1 stop3h 59m
Delta
Wed 4/155:42 am
GSP
- SGF
1 stop6h 19m
Delta
Deal found 3/15![Delta logo]()
$557
Last-minute flights from Missouri to GreenvilleDiscover last-minute flight deals from Missouri to Greenville. Data last updated March 17, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Greenville. Data last updated March 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:28 am
MCI
- GSP
1 stop4h 33m
American Airlines
Thu 4/95:12 pm
GSP
- MCI
1 stop7h 55m
American Airlines
Deal found 3/12![American Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:55 pm
SGF
- GSP
1 stop3h 59m
Delta
Sat 4/115:40 am
GSP
- SGF
1 stop6h 27m
Delta
Deal found 3/15![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:05 pm
MCI
- GSP
1 stop6h 42m
United Airlines
Tue 4/216:30 am
GSP
- MCI
1 stop4h 57m
United Airlines
Deal found 3/12![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:30 pm
MCI
- GSP
2 stops6h 10m
Southwest
Tue 4/215:05 pm
GSP
- MCI
2 stops6h 25m
Southwest
Deal found 3/12![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Tue 4/215:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Deal found 3/15![Southwest logo]()
$337
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:42 pm
STL
- GSP
1 stop5h 37m
American Airlines
Sat 4/1811:31 am
GSP
- STL
1 stop6h 10m
American Airlines
Deal found 3/13![American Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Sat 4/1810:45 am
GSP
- STL
2 stops8h 25m
Southwest
Deal found 3/13![Southwest logo]()
$316
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:06 am
STL
- GSP
1 stop6h 09m
American Airlines
Sun 4/268:16 pm
GSP
- STL
1 stop4h 30m
American Airlines
Deal found 3/14![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:35 am
STL
- GSP
1 stop3h 25m
Southwest
Wed 4/298:20 am
GSP
- STL
1 stop7h 55m
Southwest
Deal found 3/12![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:25 am
STL
- GSP
2 stops8h 25m
Southwest
Mon 5/46:25 pm
GSP
- STL
1 stop3h 30m
Southwest
Deal found 3/13![Southwest logo]()
$351
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:30 am
STL
- GSP
1 stop4h 24m
United Airlines
Wed 4/296:30 am
GSP
- STL
1 stop6h 52m
United Airlines
Deal found 3/12![United Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:45 pm
STL
- GSP
2 stops6h 55m
Southwest
Wed 4/295:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Deal found 3/12![Southwest logo]()
$308
One-way flights from Missouri to GreenvilleSearch for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
Search for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- GSP
2 stops15h 49m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:27 pm
STL
- GSP
2 stops15h 02m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$153
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/283:11 pm
MCI
- GSP
1 stop6h 51m
American Airlines
Deal found 3/14![American Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:19 pm
STL
- GSP
1 stop14h 10m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$166
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:42 pm
STL
- GSP
1 stop5h 37m
American Airlines
Deal found 3/13![American Airlines logo]()
$169
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:40 pm
STL
- GSP
2 stops8h 00m
Southwest
Deal found 3/14![Southwest logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:27 pm
STL
- GSP
2 stops42h 51m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$181
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:42 pm
STL
- GSP
1 stop5h 37m
American Airlines
Deal found 3/13![American Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:35 am
MCI
- GSP
1 stop5h 34m
American Airlines
Deal found 3/16![American Airlines logo]()
$196
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
MCI
- GSP
1 stop8h 19m
United Airlines
Deal found 3/13![United Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/174:20 pm
STL
- GSP
2 stops6h 05m
Southwest
Deal found 3/15![Southwest logo]()
$199
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:26 pm
MCI
- GSP
1 stop5h 04m
American Airlines
Deal found 3/14![American Airlines logo]()
$204
Find flight deals from Missouri to Greenville
Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated March 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $287 (United Airlines) |
One-way from | $150 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $525 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Tue 4/14
1:05 pm-8:47 pm
1 stop6h 42m
Greenville
Tue 4/21
6:30 am-10:27 am
1 stop4h 57m
$287
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Tue 4/7
2:33 pm-11:02 pm
2 stops7h 29m
Greenville
Thu 4/9
5:12 pm-12:07 am
1 stop7h 55m
$303
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Mon 4/27
7:35 am-12:00 pm
1 stop3h 25m
Greenville
Wed 4/29
8:20 am-3:15 pm
1 stop7h 55m
$311
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Tue 5/19
1:40 pm-9:40 pm
2 stops7h 00m
Greenville
Thu 5/28
6:25 pm-11:35 pm
1 stop6h 10m
$326
SpringfieldGreenville
SGF - GSP
SGFGSP
Springfield-Branson
Mon 8/10
6:45 pm-11:38 pm
1 stop3h 53m
Greenville
Sat 8/15
5:05 pm-10:29 pm
1 stop6h 24m
$329
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Thu 5/14
3:20 pm-10:15 pm
2 stops5h 55m
Greenville
Mon 5/18
6:25 pm-11:35 pm
1 stop6h 10m
$354
SpringfieldGreenville
SGF - GSP
SGFGSP
Springfield-Branson
Tue 4/7
3:56 pm-9:52 pm
1 stop4h 56m
Greenville
Wed 4/15
5:42 am-11:01 am
1 stop6h 19m
$374
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Sat 5/9
2:25 pm-9:35 pm
2 stops6h 10m
Greenville
Thu 5/14
12:35 pm-11:55 pm
2 stops12h 20m
$378
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Sat 5/2
7:45 am-2:10 pm
1 stop5h 25m
Greenville
Tue 5/5
6:27 pm-11:57 pm
1 stop6h 30m
$380
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Tue 3/31
9:55 am-4:52 pm
1 stop5h 57m
Greenville
Wed 4/8
6:30 am-10:27 am
1 stop4h 57m
$387
Showing 1-10 of 41 resultsSorted by cheapest first
Best time to book a flight from Missouri to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
MCI-GSP
STL-GSP
SGF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Greenville
USMO-GSP
MCI-GSP
STL-GSP
SGF-GSP
What is the cheapest month to book a flight from Missouri to Greenville?
Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $137). Flying from Missouri to Greenville in March is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Duncan
Seneca
Anderson
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Greenville
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Complete your trip
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Search flights from Missouri to Greenville by cabin class
Find flights from Missouri to Greenville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 17, 2026.
Missouri and Greenville flights
Browse other Missouri and Greenville flight options. Last updated on March 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Greenville flights
Consider these flights traveling from Missouri to Greenville.
Top 3 airlines flying from Missouri to Greenville
Discover the top 3 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$172 | Average$412 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$359 | Average$438 | FlexibilityNo cancel fee | On-time63% |