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Greenville

$133+ Cheap flights from Missouri to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/611:18 am
STL
-
GSP
1 stop7h 20m
Multiple Airlines
Mon 2/98:18 pm
GSP
-
STL
1 stop27h 09m
Multiple Airlines
Deal found 1/25$230
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:26 am
MCI
-
GSP
1 stop29h 33m
Multiple Airlines
Thu 3/52:58 pm
GSP
-
MCI
2 stops26h 25m
Multiple Airlines
Deal found 1/27$239
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:00 pm
MCI
-
GSP
1 stop4h 40m
Southwest
Tue 3/246:25 pm
GSP
-
MCI
1 stop5h 40m
Southwest
Deal found 1/27$287
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:48 pm
MCI
-
GSP
1 stop6h 06m
Delta
Thu 4/98:30 am
GSP
-
MCI
1 stop4h 50m
Delta
Deal found 1/28$304
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/163:33 pm
STL
-
GSP
1 stop5h 49m
American Airlines
Wed 3/187:40 am
GSP
-
STL
1 stop8h 55m
American Airlines
Deal found 1/27$308
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/161:40 pm
STL
-
GSP
1 stop7h 10m
Southwest
Wed 3/1812:35 pm
GSP
-
STL
2 stops8h 25m
Southwest
Deal found 1/27$314
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/85:42 pm
STL
-
GSP
1 stop24h 56m
Multiple Airlines
Thu 2/125:17 pm
GSP
-
STL
2 stops38h 34m
Multiple Airlines
Deal found 1/26$320
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:40 pm
STL
-
GSP
1 stop7h 10m
Southwest
Mon 3/306:25 pm
GSP
-
STL
1 stop3h 35m
Southwest
Deal found 1/26$321
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1511:26 am
MCI
-
GSP
2 stops31h 41m
Multiple Airlines
Thu 2/195:17 pm
GSP
-
MCI
1 stop18h 13m
Multiple Airlines
Deal found 1/25$331
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:30 am
MCI
-
GSP
1 stop5h 06m
American Airlines
Thu 4/25:00 am
GSP
-
MCI
1 stop7h 20m
American Airlines
Deal found 1/27$337
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1512:38 pm
MCI
-
GSP
1 stop7h 22m
American Airlines
Thu 2/196:00 am
GSP
-
MCI
1 stop7h 08m
American Airlines
Deal found 1/25$340
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:50 am
MCI
-
GSP
1 stop6h 25m
Southwest
Mon 4/276:25 pm
GSP
-
MCI
1 stop6h 10m
Southwest
Deal found 1/26$350

Find flight deals from Missouri to Greenville

Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$239
(Kiwi.com)

One-way from

$133
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$406
Provider with most accurate pricing for Lambert-St Louis-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Greenville flights.
Search Deals
From Missouri to Greenville
Search Deals
One-way flight from Missouri to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Missouri

Fly to

Greenville

Route

Depart

Return

Price

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Thu 2/26

11:26 am-5:59 pm

1 stop29h 33m

Greenville

Thu 3/5

2:58 pm-4:23 pm

2 stops26h 25m

$239

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Wed 3/18

5:00 pm-10:40 pm

1 stop4h 40m

Greenville

Tue 3/24

6:25 pm-11:05 pm

1 stop5h 40m

$287

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Tue 4/7

4:48 pm-11:54 pm

1 stop6h 06m

Greenville

Thu 4/9

8:30 am-12:20 pm

1 stop4h 50m

$304

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 3/16

3:33 pm-10:22 pm

1 stop5h 49m

Greenville

Wed 3/18

7:40 am-3:35 pm

1 stop8h 55m

$308

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sun 2/8

5:42 pm-7:38 pm

1 stop24h 56m

Greenville

Thu 2/12

5:17 pm-6:51 am

2 stops38h 34m

$320

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 3/26

1:40 pm-9:50 pm

1 stop7h 10m

Greenville

Mon 3/30

6:25 pm-9:00 pm

1 stop3h 35m

$321

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Tue 4/7

3:32 pm-9:31 pm

1 stop4h 59m

Greenville

Thu 4/9

7:00 am-12:40 pm

1 stop6h 40m

$321

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Tue 3/31

5:30 am-11:36 am

1 stop5h 06m

Greenville

Thu 4/2

5:00 am-11:20 am

1 stop7h 20m

$337

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sun 2/15

12:38 pm-9:00 pm

1 stop7h 22m

Greenville

Thu 2/19

6:00 am-12:08 pm

1 stop7h 08m

$340

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 3/16

2:15 pm-10:45 pm

2 stops7h 30m

Greenville

Wed 3/18

12:35 pm-8:00 pm

2 stops8h 25m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 37 results
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Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Greenville

What is the cheapest month to book a flight from Missouri to Greenville?

Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $137). Flying from Missouri to Greenville in June is currently the most expensive (average of $237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Missouri?

    Most people fly into Greenville (GSP) if they book a flight to Greenville from Missouri. Greenville is conveniently located just 10.4 mi from Greenville’s city center.

  • How long is the flight from Missouri to Greenville?

    Airlines like Southwest, American Airlines, and United Airlines fly from Missouri to Greenville in about 4h 40m. The time it takes to get you to your destination can typically vary by up to 9h 19m. Airlines will cover a distance of 752 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Greenville?

    The most popular flight routes from Missouri to Greenville are Kansas City - Greenville, Lambert-St Louis - Greenville and Springfield-Branson - Greenville.

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $137). Flying from Missouri to Greenville in June is currently the most expensive (average of $237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Missouri to Greenville

Discover the top 2 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$359FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$413FlexibilityNo cancel feeOn-time71%

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