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Greenville

$136+ Cheap flights from Iowa to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSP
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Iowa to Greenville

Keep the following information in mind while searching for Iowa to Greenville flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$233
(Delta)

One-way from

$136
(Delta)

Popular in

November

Cheapest in

August

Average price

$432
Provider with most accurate pricing for Des Moines-Greenville flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Greenville flights.
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From Iowa to Greenville
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One-way flight from Iowa to Greenville
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Highest demand for flights based on searches. 15% potential increase in price ($73 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Iowa to Greenville

Cheapest flights from Iowa to Greenville
Explore the most affordable flight options available from Iowa to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/175:27 pmMLI - GSP
1 stop5h 30mDelta
Tue 7/16:00 pmGSP - MLI
1 stop5h 47mDelta
Deal found 4/29$233
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/161:36 pmCID - GSP
1 stop8h 07mAmerican Airlines
Tue 5/206:36 pmGSP - CID
1 stop4h 27mAmerican Airlines
Deal found 5/1$259
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/165:25 pmMLI - GSP
1 stop4h 35mUnited Airlines
Tue 5/206:45 amGSP - MLI
1 stop4h 26mUnited Airlines
Deal found 5/1$259
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:25 pmMLI - GSP
1 stop6h 18mAmerican Airlines
Tue 5/205:26 amGSP - MLI
2 stops6h 16mAmerican Airlines
Deal found 5/1$264
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:00 amOMA - GSP
1 stop7h 59mUnited Airlines
Tue 6/109:30 amGSP - OMA
1 stop5h 54mUnited Airlines
Deal found 5/1$271
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/45:00 amOMA - GSP
2 stops8h 05mAmerican Airlines
Tue 6/106:01 pmGSP - OMA
2 stops6h 58mAmerican Airlines
Deal found 5/1$281
This Mytrip deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/153:48 pmDSM - GSP
1 stop15h 58mAllegiant Air
Sun 6/2210:14 pmGSP - DSM
1 stop19h 00mAllegiant Air
Deal found 5/1$296
This Mytrip deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:23 pmCID - GSP
1 stop18h 19mAllegiant Air
Sun 11/23:32 pmGSP - CID
1 stop25h 42mAllegiant Air
Deal found 5/1$304
This Mytrip deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/156:32 pmDSM - GSP
2 stops25h 01mMultiple Airlines
Sun 6/2210:14 pmGSP - DSM
1 stop19h 00mMultiple Airlines
Deal found 5/1$337
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/233:06 pmALO - GSP
1 stop5h 30mAmerican Airlines
Wed 10/2911:27 amGSP - ALO
1 stop4h 09mAmerican Airlines
Deal found 4/29$344
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/611:57 amCID - GSP
2 stops10h 55mDelta
Sun 6/87:59 pmGSP - CID
1 stop3h 54mDelta
Deal found 4/30$349
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:37 amCID - GSP
1 stop4h 27mUnited Airlines
Mon 7/282:52 pmGSP - CID
2 stops7h 34mUnited Airlines
Deal found 4/29$379

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Iowa to Greenville that are best for you.

Fly from

Iowa

Fly to

Greenville

Route

Depart

Return

Price

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Tue 6/17

5:27 pm-11:57 pm

1 stop5h 30m

Greenville

Tue 7/1

6:00 pm-10:47 pm

1 stop5h 47m

$233

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Fri 5/16

1:36 pm-10:43 pm

1 stop8h 07m

Greenville

Tue 5/20

6:36 pm-10:03 pm

1 stop4h 27m

$259

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Fri 5/16

5:25 pm-11:00 pm

1 stop4h 35m

Greenville

Tue 5/20

6:45 am-10:11 am

1 stop4h 26m

$259

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Fri 5/16

3:25 pm-10:43 pm

1 stop6h 18m

Greenville

Tue 5/20

5:26 am-10:42 am

2 stops6h 16m

$264

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Wed 6/4

6:00 am-2:59 pm

1 stop7h 59m

Greenville

Tue 6/10

9:30 am-2:24 pm

1 stop5h 54m

$271

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Wed 6/4

5:00 am-2:05 pm

2 stops8h 05m

Greenville

Tue 6/10

6:01 pm-11:59 pm

2 stops6h 58m

$281

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sun 6/15

3:48 pm-8:46 am

1 stop15h 58m

Greenville

Sun 6/22

10:14 pm-4:14 pm

1 stop19h 00m

$296

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sun 6/15

6:32 pm-8:33 pm

2 stops25h 01m

Greenville

Sun 6/22

10:14 pm-4:14 pm

1 stop19h 00m

$337

WaterlooGreenville

ALO - GSP

ALOGSP

Waterloo

Thu 10/23

3:06 pm-9:36 pm

1 stop5h 30m

Greenville

Wed 10/29

11:27 am-2:36 pm

1 stop4h 09m

$344

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Fri 6/6

11:57 am-11:52 pm

2 stops10h 55m

Greenville

Sun 6/8

7:59 pm-10:53 pm

1 stop3h 54m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 20 results
1
2

Best time to book a flight from Iowa to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Greenville

What is the cheapest month to book a flight from Iowa to Greenville?

Currently, January is the cheapest month in which you can book a flight from Iowa to Greenville (average of $329). Flying from Iowa to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to GSP?

Find hourly flight availability from Iowa to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Iowa to Greenville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated May 1, 2025.
Read through reviews of airlines operating flights from Iowa to Greenville, such as Delta, United Airlines and Allegiant Air. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Iowa to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Iowa?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Greenville.

  • What are the cheapest airlines to fly from Iowa to Greenville one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $136. Users have also found prices from $141 and $370 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Iowa to Greenville?

    When deciding which route to take from Iowa to Greenville consider Cedar Rapids - Greenville, Moline Quad-City - Greenville or Des Moines - Greenville as they are the most popular.

  • Can I find deals for flights from Iowa to Greenville that include hotel bookings?

    Yes. In addition to deals on Iowa to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Greenville.

  • Can I find deals for business class flights from Iowa to Greenville?

    Yes. Cheapflights offers flight deals from Iowa to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Greenville (average of $329). Flying from Iowa to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
Simpsonville
Seneca
Duncan
Anderson

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Alternative routes for Iowa to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Greenville

Discover the top 3 airlines that operate flights from Iowa to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$352FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$373FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$318Average$477FlexibilityNo cancel feeOn-time69%

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