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$119+ Cheap flights from Iowa to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSP
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Iowa to Greenville

Keep the following information in mind while searching for Iowa to Greenville flight deals. Data was last updated August 14, 2025.

Round-trip from

$209
(American Airlines)

One-way from

$119
(American Airlines)

Popular in

November

Cheapest in

June

Average price

$389
From Iowa to Greenville
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One-way flight from Iowa to Greenville
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Highest demand for flights based on searches. 18% potential increase in price ($97 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Iowa to Greenville

Cheapest flights from Iowa to Greenville
Explore the most affordable flight options available from Iowa to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:11 amOMA - GSP
1 stop5h 35mAmerican Airlines
Tue 9/307:38 pmGSP - OMA
1 stop4h 29mAmerican Airlines
Deal found 8/13$209
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/124:09 pmDSM - GSP
1 stop5h 21mAmerican Airlines
Tue 9/167:38 pmGSP - DSM
1 stop4h 28mAmerican Airlines
Deal found 8/13$230
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/133:57 pmOMA - GSP
1 stop4h 10mDelta
Wed 9/176:13 pmGSP - OMA
1 stop4h 04mDelta
Deal found 8/13$237
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:11 pmDSM - GSP
1 stop4h 41mAmerican Airlines
Mon 9/157:38 pmGSP - DSM
1 stop4h 28mAmerican Airlines
Deal found 8/13$237
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/137:08 amOMA - GSP
2 stops8h 06mAmerican Airlines
Thu 9/188:37 pmGSP - OMA
1 stop4h 29mAmerican Airlines
Deal found 8/13$242
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:08 amDSM - GSP
2 stops8h 06mAmerican Airlines
Mon 10/67:11 pmGSP - DSM
1 stop5h 48mAmerican Airlines
Deal found 8/13$242
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:50 pmDSM - GSP
1 stop5h 10mAmerican Airlines
Mon 9/157:44 pmGSP - DSM
1 stop5h 01mAmerican Airlines
Deal found 8/13$244
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amCID - GSP
1 stop5h 47mDelta
Sun 10/125:30 amGSP - CID
2 stops7h 17mDelta
Deal found 8/13$254
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:10 pmOMA - GSP
1 stop4h 42mDelta
Wed 9/176:13 pmGSP - OMA
1 stop6h 43mDelta
Deal found 8/13$259
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:37 pmMLI - GSP
1 stop5h 21mAmerican Airlines
Wed 12/36:38 pmGSP - MLI
1 stop4h 07mAmerican Airlines
Deal found 8/13$279
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:00 amDSM - GSP
2 stops11h 05mSouthwest
Tue 9/169:30 amGSP - DSM
2 stops13h 50mSouthwest
Deal found 8/13$280
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1612:04 pmOMA - GSP
2 stops9h 54mAmerican Airlines
Wed 9/177:36 amGSP - OMA
1 stop4h 55mAmerican Airlines
Deal found 8/13$284

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Iowa to Greenville that are best for you.

Fly from

Iowa

Fly to

Greenville

Route

Depart

Return

Price

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Tue 9/30

5:11 am-11:46 am

1 stop5h 35m

Greenville

Tue 9/30

7:38 pm-11:07 pm

1 stop4h 29m

$209

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Fri 9/12

4:09 pm-10:30 pm

1 stop5h 21m

Greenville

Tue 9/16

7:38 pm-11:06 pm

1 stop4h 28m

$230

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Wed 9/17

2:08 pm-9:34 pm

1 stop6h 26m

Greenville

Mon 9/22

6:13 pm-9:17 pm

1 stop4h 04m

$237

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Tue 9/16

12:30 pm-10:41 pm

1 stop9h 11m

Greenville

Mon 9/22

6:13 pm-11:56 pm

1 stop6h 43m

$237

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Sat 11/1

1:57 pm-9:11 pm

1 stop6h 14m

Greenville

Thu 11/6

11:28 am-5:55 pm

1 stop7h 27m

$237

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Mon 9/15

6:10 pm-11:52 pm

1 stop4h 42m

Greenville

Mon 9/22

6:13 pm-11:56 pm

1 stop6h 43m

$237

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Thu 9/11

6:15 am-12:37 pm

1 stop5h 22m

Greenville

Mon 9/15

6:33 pm-11:22 pm

1 stop5h 49m

$237

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Tue 9/16

2:55 pm-9:07 pm

1 stop5h 12m

Greenville

Sat 9/20

5:30 am-9:36 am

1 stop5h 06m

$237

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Tue 9/16

2:55 pm-9:07 pm

1 stop5h 12m

Greenville

Wed 9/17

3:30 pm-9:14 pm

1 stop6h 44m

$237

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sat 10/4

9:34 am-4:57 pm

1 stop6h 23m

Greenville

Mon 10/6

7:11 pm-11:59 pm

1 stop5h 48m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 41 results
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Best time to book a flight from Iowa to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Greenville

What is the cheapest month to book a flight from Iowa to Greenville?

Currently, January is the cheapest month in which you can book a flight from Iowa to Greenville (average of $329). Flying from Iowa to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to GSP?

Find hourly flight availability from Iowa to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

When flying from Iowa to Greenville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Iowa?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Greenville.

  • What are the cheapest airlines to fly from Iowa to Greenville one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $119. Users have also found prices from $126 and $214 on Delta and Southwest, respectively.

  • What are the most popular routes from Iowa to Greenville?

    When deciding which route to take from Iowa to Greenville consider Cedar Rapids - Greenville, Omaha Eppley Airfield - Greenville or Des Moines - Greenville as they are the most popular.

  • Can I find deals for flights from Iowa to Greenville that include hotel bookings?

    Yes. In addition to deals on Iowa to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Greenville.

  • Can I find deals for business class flights from Iowa to Greenville?

    Yes. Cheapflights offers flight deals from Iowa to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Greenville (average of $329). Flying from Iowa to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Alternative routes for Iowa to Greenville

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Top 3 airlines flying from Iowa to Greenville

Discover the top 3 airlines that operate flights from Iowa to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$406FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$399FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$477FlexibilityNo cancel feeOn-time69%

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