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Greenville

$159+ Cheap flights from Iowa to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSP
apr 10 — apr 171
ven 4/10
ven 4/17
1 adult, Economy
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Cheap flight deals from Iowa to Greenville

Cheapest flights from Iowa to Greenville
Explore the most affordable flight options available from Iowa to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 11, 2026.

This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/45:35 am
CID
-
GSP
1 stop5h 40m
American Airlines
mar 4/78:16 pm
GSP
-
CID
1 stop4h 34m
American Airlines
Deal found 3/8$289
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 6/1411:00 am
MLI
-
GSP
1 stop4h 13m
Delta
lun 6/226:45 am
GSP
-
MLI
1 stop4h 41m
Delta
Deal found 3/7$289
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 3/266:36 am
CID
-
GSP
1 stop4h 39m
American Airlines
lun 3/308:17 pm
GSP
-
CID
1 stop4h 16m
American Airlines
Deal found 3/6$294
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 3/316:00 am
MLI
-
GSP
2 stops6h 15m
American Airlines
sab 4/47:40 am
GSP
-
MLI
1 stop6h 41m
American Airlines
Deal found 3/7$294
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 3/241:24 pm
CID
-
GSP
1 stop8h 21m
American Airlines
sab 3/286:01 am
GSP
-
CID
1 stop7h 36m
American Airlines
Deal found 3/9$299
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 3/242:02 pm
MLI
-
GSP
1 stop4h 44m
American Airlines
sab 3/284:30 pm
GSP
-
MLI
1 stop7h 23m
American Airlines
Deal found 3/8$299
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 11/265:00 pm
MLI
-
GSP
1 stop5h 37m
Delta
mer 12/26:45 am
GSP
-
MLI
1 stop4h 41m
Delta
Deal found 3/10$309
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/196:30 am
CID
-
GSP
2 stops6h 47m
United Airlines
dom 5/246:00 am
GSP
-
CID
1 stop6h 58m
United Airlines
Deal found 3/9$314
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 11/265:37 pm
MLI
-
GSP
1 stop5h 21m
American Airlines
mer 12/211:33 am
GSP
-
MLI
2 stops7h 38m
American Airlines
Deal found 3/10$314
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 7/116:06 pm
CID
-
GSP
1 stop12h 29m
Allegiant Air
ven 7/173:10 pm
GSP
-
CID
1 stop28h 20m
Allegiant Air
Deal found 3/6$319
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 7/97:24 pm
CID
-
GSP
1 stop18h 01m
Allegiant Air
lun 7/133:10 pm
GSP
-
CID
1 stop21h 36m
Allegiant Air
Deal found 3/6$321
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 6/1311:00 am
MLI
-
GSP
1 stop4h 13m
Delta
lun 6/226:45 am
GSP
-
MLI
1 stop4h 41m
Delta
Deal found 3/7$323

Find flight deals from Iowa to Greenville

Keep the following information in mind while searching for Iowa to Greenville flight deals. Data was last updated marzo 11, 2026.

Round-trip from

$289
(American Airlines)

One-way from

$159
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$395
From Iowa to Greenville
Search Deals
One-way flight from Iowa to Greenville
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 11, 2026.
Use the filters below to find and compare flights from Iowa to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

lun 6/15

11:00 am-4:13 pm

1 stop4h 13m

Greenville

dom 6/21

6:45 am-10:26 am

1 stop4h 41m

$289

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

sab 3/28

1:10 pm-11:59 pm

2 stops9h 49m

Greenville

lun 3/30

6:30 am-10:35 am

1 stop5h 05m

$299

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

mar 3/24

2:02 pm-7:46 pm

1 stop4h 44m

Greenville

sab 3/28

4:30 pm-10:53 pm

1 stop7h 23m

$299

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

mar 3/24

10:04 am-6:32 pm

2 stops7h 28m

Greenville

sab 3/28

6:01 am-12:37 pm

1 stop7h 36m

$304

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

sab 6/13

11:00 am-4:13 pm

1 stop4h 13m

Greenville

mer 6/17

6:45 am-10:26 am

1 stop4h 41m

$323

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

mer 3/25

10:46 am-11:59 pm

2 stops12h 13m

Greenville

dom 3/29

6:30 am-9:58 am

1 stop4h 28m

$324

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

mar 5/26

5:30 am-4:20 pm

2 stops9h 50m

Greenville

lun 6/1

1:50 pm-11:05 pm

2 stops10h 15m

$353

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

ven 3/27

10:46 am-11:59 pm

2 stops12h 13m

Greenville

lun 3/30

6:30 am-9:58 am

1 stop4h 28m

$354
Quickest round-trip

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

lun 5/4

6:31 pm-11:56 pm

1 stop4h 25m

Greenville

gio 5/7

10:09 am-1:37 pm

1 stop4h 28m

$355

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

mer 4/1

5:00 am-10:56 am

1 stop4h 56m

Greenville

lun 4/6

8:17 pm-11:48 pm

1 stop4h 31m

$355

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 43 resultsSorted by cheapest first
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Best time to book a flight from Iowa to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Greenville

What is the cheapest month to book a flight from Iowa to Greenville?

Currently, September is the cheapest month in which you can book a flight from Iowa to Greenville (average of $198). Flying from Iowa to Greenville in May is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Iowa?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Greenville.

  • How long is the flight from Iowa to Greenville?

    There are many flights that can get you from Iowa to Greenville in 4h 13m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. There are 637 mi between Iowa and Greenville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Greenville?

    When deciding which route to take from Iowa to Greenville consider Cedar Rapids - Greenville, Des Moines - Greenville or Omaha Eppley Airfield - Greenville as they are the most popular.

  • Can I find deals for flights from Iowa to Greenville that include hotel bookings?

    Yes. In addition to deals on Iowa to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Greenville.

  • Can I find deals for business class flights from Iowa to Greenville?

    Yes. Cheapflights offers flight deals from Iowa to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Greenville?

    Currently, September is the cheapest month in which you can book a flight from Iowa to Greenville (average of $198). Flying from Iowa to Greenville in May is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Iowa to Greenville

Discover the top 3 airlines that operate flights from Iowa to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$243Average$406FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$472FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$253Average$362FlexibilityNo cancel feeOn-time71%

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