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$254+ Cheap flights from Iowa to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSP
Feb 1 — Feb 81
Sun 2/1
Sun 2/8
1 adult, Economy
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Cheap flight deals from Iowa to Greenville

Best flights from Iowa to Greenville
Discover carefully curated flight deals from Iowa to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 2, 2026.

This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2910:05 amCID - GSP
1 stop5h 37mAmerican Airlines
Sun 2/14:40 pmGSP - CID
1 stop5h 51mAmerican Airlines
Deal found 12/31$269
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:35 amDSM - GSP
1 stop8h 39mDelta
Wed 2/255:40 amGSP - DSM
1 stop6h 39mDelta
Deal found 12/31$293
This Kiwi.com deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/158:30 amDSM - GSP
1 stop6h 24mMultiple Airlines
Sun 2/225:17 pmGSP - DSM
2 stops27h 31mMultiple Airlines
Deal found 12/31$337
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/173:21 pmOMA - GSP
1 stop4h 26mUnited Airlines
Tue 1/204:15 pmGSP - OMA
1 stop7h 52mUnited Airlines
Deal found 12/30$339
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/63:41 pmCID - GSP
2 stops6h 45mAmerican Airlines
Mon 2/94:40 pmGSP - CID
1 stop5h 51mAmerican Airlines
Deal found 12/30$274
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:35 amDSM - GSP
1 stop8h 39mDelta
Tue 3/311:36 amGSP - DSM
1 stop8h 57mDelta
Deal found 12/31$293
This American Airlines deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/161:26 pmCID - GSP
1 stop6h 30mAmerican Airlines
Tue 1/205:40 pmGSP - CID
1 stop6h 25mAmerican Airlines
Deal found 1/1$279
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/173:35 pmDSM - GSP
1 stop4h 12mUnited Airlines
Tue 1/205:34 pmGSP - DSM
1 stop5h 16mUnited Airlines
Deal found 12/30$339
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2111:32 amCID - GSP
1 stop4h 20mUnited Airlines
Sat 1/246:35 amGSP - CID
1 stop5h 12mUnited Airlines
Deal found 12/30$339
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:15 pmDSM - GSP
1 stop5h 28mDelta
Thu 2/2611:36 amGSP - DSM
1 stop9h 00mDelta
Deal found 12/31$341
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2710:47 amMLI - GSP
1 stop5h 05mUnited Airlines
Sat 1/316:35 amGSP - MLI
1 stop4h 37mUnited Airlines
Deal found 12/30$339
This United Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:46 amMLI - GSP
2 stops12h 13mUnited Airlines
Sun 3/296:30 amGSP - MLI
1 stop4h 28mUnited Airlines
Deal found 12/31$347
This United Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2010:47 amMLI - GSP
1 stop5h 05mUnited Airlines
Fri 1/235:34 pmGSP - MLI
1 stop17h 38mUnited Airlines
Deal found 12/31$428

Find flight deals from Iowa to Greenville

Keep the following information in mind while searching for Iowa to Greenville flight deals. Data was last updated January 2, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$254
(Delta)

Popular in

November

Cheapest in

September

Average price

$386
Provider with most accurate pricing for Des Moines-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Greenville flights.
Search Deals
From Iowa to Greenville
Search Deals
One-way flight from Iowa to Greenville
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 2, 2026.
Use the filters below to find and compare flights from Iowa to Greenville that are best for you.

Fly from

Iowa

Fly to

Greenville

Route

Depart

Return

Price

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Thu 1/29

10:05 am-4:42 pm

1 stop5h 37m

Greenville

Sun 2/1

4:40 pm-9:31 pm

1 stop5h 51m

$269

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Fri 2/6

3:41 pm-11:26 pm

2 stops6h 45m

Greenville

Mon 2/9

4:40 pm-9:31 pm

1 stop5h 51m

$274

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Fri 1/16

1:26 pm-8:56 pm

1 stop6h 30m

Greenville

Tue 1/20

5:40 pm-11:05 pm

1 stop6h 25m

$279

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Wed 2/18

7:35 am-5:14 pm

1 stop8h 39m

Greenville

Wed 2/25

5:40 am-11:19 am

1 stop6h 39m

$293

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Wed 2/18

7:35 am-5:14 pm

1 stop8h 39m

Greenville

Tue 3/3

11:36 am-7:33 pm

1 stop8h 57m

$293

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sun 2/15

8:30 am-3:54 pm

1 stop6h 24m

Greenville

Sun 2/22

5:17 pm-7:48 pm

2 stops27h 31m

$337

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Sat 1/17

3:21 pm-8:47 pm

1 stop4h 26m

Greenville

Tue 1/20

4:15 pm-11:07 pm

1 stop7h 52m

$339

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sat 1/17

3:35 pm-8:47 pm

1 stop4h 12m

Greenville

Tue 1/20

5:34 pm-9:50 pm

1 stop5h 16m

$339

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Wed 1/21

11:32 am-4:52 pm

1 stop4h 20m

Greenville

Sat 1/24

6:35 am-10:47 am

1 stop5h 12m

$339

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Tue 1/27

10:47 am-4:52 pm

1 stop5h 05m

Greenville

Sat 1/31

6:35 am-10:12 am

1 stop4h 37m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/31

Showing 1-10 of 16 results
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Best time to book a flight from Iowa to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Greenville

What is the cheapest month to book a flight from Iowa to Greenville?

Currently, September is the cheapest month in which you can book a flight from Iowa to Greenville (average of $198). Flying from Iowa to Greenville in January is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Iowa?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Greenville.

  • How long is the flight from Iowa to Greenville?

    There are many flights that can get you from Iowa to Greenville in 4h 26m. Fly via American Airlines, Delta, or United Airlines to get the fastest option. There are 863 mi between Iowa and Greenville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Greenville?

    When deciding which route to take from Iowa to Greenville consider Cedar Rapids - Greenville, Omaha Eppley Airfield - Greenville or Des Moines - Greenville as they are the most popular.

  • Can I find deals for flights from Iowa to Greenville that include hotel bookings?

    Yes. In addition to deals on Iowa to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Greenville.

  • Can I find deals for business class flights from Iowa to Greenville?

    Yes. Cheapflights offers flight deals from Iowa to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Greenville?

    Currently, September is the cheapest month in which you can book a flight from Iowa to Greenville (average of $198). Flying from Iowa to Greenville in January is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Iowa to Greenville

Discover the top 3 airlines that operate flights from Iowa to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$415FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$472FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$378FlexibilityNo cancel feeOn-time71%

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