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$189+ Cheap flights from Knoxville to Gainesville (TYS - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GNV
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Knoxville to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$234
(American Airlines)

One-way from

$189
(Delta)

Popular in

October

Cheapest in

September

Average price

$710
Provider with most accurate pricing for Knoxville McGhee Tyson-Gainesville Regional flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Gainesville Regional flights.
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From Knoxville McGhee Tyson to Gainesville Regional
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One-way flight from Knoxville McGhee Tyson to Gainesville Regional
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Highest demand for flights based on searches. 6% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to Gainesville

Cheapest flights from Knoxville to Gainesville
Explore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:56 pmTYS - GNV
1 stop7h 03mAmerican Airlines
Tue 11/181:02 pmGNV - TYS
1 stop3h 51mAmerican Airlines
Deal found 10/27$234
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:44 amTYS - GNV
1 stop3h 42mDelta
Mon 11/107:04 pmGNV - TYS
1 stop4h 37mDelta
Deal found 10/27$259
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:44 amTYS - GNV
1 stop3h 42mDelta
Mon 11/107:04 pmGNV - TYS
1 stop4h 37mDelta
Deal found 10/27$279
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:44 amTYS - GNV
1 stop3h 42mDelta
Sun 11/93:46 pmGNV - TYS
1 stop3h 16mDelta
Deal found 10/27$289
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:07 pmTYS - GNV
1 stop6h 52mAmerican Airlines
Mon 11/106:45 pmGNV - TYS
1 stop4h 06mAmerican Airlines
Deal found 10/27$333
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:15 pmTYS - GNV
2 stops7h 44mAmerican Airlines
Sun 11/164:47 pmGNV - TYS
1 stop6h 07mAmerican Airlines
Deal found 10/29$338

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.

Fly from

Knoxville

Fly to

Gainesville

Route

Depart

Return

Price

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 11/15

4:15 pm-11:59 pm

2 stops7h 44m

Gainesville Regional

Tue 11/18

4:59 pm-9:17 pm

1 stop4h 18m

$239

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 11/14

5:35 am-9:26 am

1 stop3h 51m

Gainesville Regional

Mon 11/17

6:00 am-9:37 am

1 stop3h 37m

$244

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 11/14

5:35 am-9:26 am

1 stop3h 51m

Gainesville Regional

Sun 11/16

6:00 am-10:45 am

1 stop4h 45m

$259

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Thu 11/6

5:44 am-9:26 am

1 stop3h 42m

Gainesville Regional

Mon 11/10

7:04 pm-11:41 pm

1 stop4h 37m

$259

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 11/1

6:15 am-9:26 am

1 stop3h 11m

Gainesville Regional

Mon 11/10

7:04 pm-11:41 pm

1 stop4h 37m

$279

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 11/15

8:45 am-12:52 pm

1 stop4h 07m

Gainesville Regional

Sun 11/16

7:04 pm-11:41 pm

1 stop4h 37m

$289

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 11/1

6:15 am-9:26 am

1 stop3h 11m

Gainesville Regional

Sun 11/9

3:46 pm-7:02 pm

1 stop3h 16m

$289

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 11/15

4:15 pm-11:59 pm

2 stops7h 44m

Gainesville Regional

Sun 11/16

4:47 pm-10:54 pm

1 stop6h 07m

$338

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Tue 1/27

5:30 am-9:26 am

1 stop3h 56m

$189

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Mon 1/26

5:24 pm-11:57 pm

1 stop6h 33m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 16 results
1
2

Compare providers for flights from Knoxville to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Gainesville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Gainesville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Gainesville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Gainesville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Gainesville

What is the cheapest month to book a flight from Knoxville to Gainesville?

Currently, July is the cheapest month in which you can book a flight from Knoxville to Gainesville (average of $60). Flying from Knoxville to Gainesville in December is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to GNV?

Find hourly flight availability from Knoxville to Gainesville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s optimal to fly from Knoxville to Gainesville in the evening. By choosing this option you can save up to 60% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Knoxville to Gainesville?

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated October 29, 2025.
See what other customers who have flown with Delta from Knoxville to Gainesville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Overall

7.9

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Gainesville?

    For as low as $244, American Airlines can have you in Gainesville from Knoxville in 3h 51m. There are 434 mi between Knoxville and Gainesville. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Knoxville to Gainesville round-trip?

    According to our current data, Delta ($228), offers the cheapest pricing from Knoxville to Gainesville. Delta is priced at 51% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Gainesville that include hotel bookings?

    Yes. In addition to deals on Knoxville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Gainesville.

  • Can I find deals for business class flights from Knoxville to Gainesville?

    Yes. Cheapflights offers flight deals from Knoxville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Gainesville?

    Currently, July is the cheapest month in which you can book a flight from Knoxville to Gainesville (average of $60). Flying from Knoxville to Gainesville in December is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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Top airline flying from Knoxville to Gainesville

Discover the top airline that operate flights from Knoxville to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$488FlexibilityNo cancel feeOn-timeN/A

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