What are the cheapest airlines flying from Knoxville to Gainesville round-trip?

According to our current data, Delta ($229), and American Airlines ($234) offers the cheapest pricing from Knoxville to Gainesville. Delta is priced at 54% lower than the current average price of a flight leaving 3 months from now.

What is the cheapest day to fly from Knoxville to Gainesville?

Travelers seeking maximum savings on their Knoxville to Gainesville flight should consider departing on Saturday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Gainesville ranges from 2.1 - 7.1 inches per month. June is typically the wettest month, when rainfall can reach 7.1 in. November is typically the driest time to visit Gainesville when rainfall is around 2.1 in.

If weather is an important factor for your trip to Gainesville, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

What is the cheapest day to fly round-trip from Knoxville to Gainesville?

Thursday flights are found to be more expensive to fly from Knoxville to Gainesville. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Gainesville.

What is the cheapest month to fly from Knoxville to Gainesville?

Due to multiple factors, expect to potentially pay more when booking in October. For low rates, July can be a great choice for travel to Gainesville. Flights to Gainesville from Knoxville in July are about $498 on average during July, but can be found for as low as $268.

Can I find deals for flights from Knoxville to Gainesville that include hotel bookings?

Yes. In addition to deals on Knoxville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Gainesville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Gainesville.

Can I find deals for business class flights from Knoxville to Gainesville?

Yes. Cheapflights offers flight deals from Knoxville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$160+ Flights from Knoxville to Gainesville

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Cheap flight deals from Knoxville to Gainesville

Round-trip from	$229 (Delta)
One-way from	$160 (Delta)
Popular in	October
Cheapest in	July
Average price	$268

From Knoxville McGhee Tyson to Gainesville Regional

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One-way flight from Knoxville McGhee Tyson to Gainesville Regional

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Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Knoxville to Gainesville

Cheapest flights from Knoxville to Gainesville
Explore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Sat 8/235:45 amTYS - GNV

1 stop3h 47mDelta

Tue 8/262:10 pmGNV - TYS

1 stop4h 53mDelta

Deal found 7/27

$229

Tue 8/267:35 pmTYS - GNV

1 stop4h 03mAmerican Airlines

Tue 9/26:00 amGNV - TYS

2 stops7h 03mAmerican Airlines

Deal found 7/29

$234

Best flights from Knoxville to Gainesville
Discover carefully curated flight deals from Knoxville to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2025.

Sat 8/235:45 amTYS - GNV

1 stop3h 47mDelta

Tue 8/262:10 pmGNV - TYS

1 stop4h 53mDelta

Deal found 7/27

$229

Tue 8/267:35 pmTYS - GNV

1 stop4h 03mAmerican Airlines

Tue 9/26:00 amGNV - TYS

2 stops7h 03mAmerican Airlines

Deal found 7/29

$234

Last-minute flights from Knoxville to Gainesville
Discover last-minute flight deals from Knoxville to Gainesville. Data last updated July 29, 2025 and is based on user searches.

Sat 8/235:45 amTYS - GNV

1 stop3h 47mDelta

Tue 8/262:10 pmGNV - TYS

1 stop4h 53mDelta

Deal found 7/27

$229

Tue 8/267:35 pmTYS - GNV

1 stop4h 03mAmerican Airlines

Tue 9/26:00 amGNV - TYS

2 stops7h 03mAmerican Airlines

Deal found 7/29

$234

One-way flights from Knoxville to Gainesville
Search for one-way flight options from Knoxville to Gainesville. Find affordable one-way fares based on user searches. Data last updated July 29, 2025.

Tue 10/282:27 pmTYS - GNV

1 stop3h 06mDelta

Deal found 7/28

$160

Fri 9/263:09 pmTYS - GNV

2 stops8h 50mAmerican Airlines

Deal found 7/26

$233

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 8/23

5:45 am-9:32 am

1 stop3h 47m

Gainesville Regional

Tue 8/26

2:10 pm-7:03 pm

1 stop4h 53m

$229

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Tue 8/26

7:35 pm-11:38 pm

1 stop4h 03m

Gainesville Regional

Tue 9/2

6:00 am-1:03 pm

2 stops7h 03m

$234

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Tue 10/28

2:27 pm-5:33 pm

1 stop3h 06m

$160

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 9/26

3:09 pm-11:59 pm

2 stops8h 50m

$233

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Knoxville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Gainesville

What is the cheapest month to book a flight from Knoxville to Gainesville?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Gainesville (average of $359). Flying from Knoxville to Gainesville in November is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to GNV?

It’s optimal to fly from Knoxville to Gainesville in the morning. By choosing this option you can save up to 3% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Gainesville

See what other customers who have flown with Delta and American Airlines from Knoxville to Gainesville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Delta

8.0

Very good

7,979 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

Related info for your journey

What are the cheapest airlines flying from Knoxville to Gainesville round-trip?
According to our current data, Delta ($229), and American Airlines ($234) offers the cheapest pricing from Knoxville to Gainesville. Delta is priced at 54% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Knoxville to Gainesville that include hotel bookings?
Yes. In addition to deals on Knoxville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Gainesville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Gainesville.
Can I find deals for business class flights from Knoxville to Gainesville?
Yes. Cheapflights offers flight deals from Knoxville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Gainesville?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Gainesville (average of $359). Flying from Knoxville to Gainesville in November is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Lake City

Alachua

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Top 2 airlines flying from Knoxville to Gainesville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$268	Average$657	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$356	Average$496	FlexibilityNo cancel fee	On-timeN/A

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$160+ Cheap flights from Knoxville to Gainesville (TYS - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Gainesville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Gainesville

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to Gainesville

Cheapest flights from Knoxville to GainesvilleExplore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Explore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.

Best time to book a flight from Knoxville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Gainesville

What is the cheapest month to book a flight from Knoxville to Gainesville?

What is the cheapest time of day to fly from TYS to GNV?

Find hourly flight availability from Knoxville to Gainesville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Reviews of airlines servicing Gainesville

See what other customers who have flown with Delta and American Airlines from Knoxville to Gainesville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Knoxville to Gainesville round-trip?

Can I find deals for flights from Knoxville to Gainesville that include hotel bookings?

How can I find direct flights from Knoxville to Gainesville?

Can I find deals for business class flights from Knoxville to Gainesville?

What is the cheapest month to book a flight from Knoxville to Gainesville?

Traveling to a place near Gainesville?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Gainesville

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Knoxville to Gainesville

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Cheapest flights from Knoxville to Gainesville
Explore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.