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$327+ Cheap flights from Knoxville to Gainesville (TYS - GNV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GNV
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from Knoxville to Gainesville

Cheapest flights from Knoxville to Gainesville
Explore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:00 am
TYS
-
GNV
1 stop5h 55m
American Airlines
Wed 4/157:59 pm
GNV
-
TYS
1 stop3h 56m
American Airlines
Deal found 3/9$327
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:47 pm
TYS
-
GNV
1 stop4h 40m
American Airlines
Fri 3/277:45 pm
GNV
-
TYS
1 stop4h 05m
American Airlines
Deal found 3/9$477
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:02 am
TYS
-
GNV
1 stop4h 13m
American Airlines
Sat 3/287:56 pm
GNV
-
TYS
1 stop3h 54m
American Airlines
Deal found 3/9$496
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:40 am
TYS
-
GNV
1 stop3h 49m
Delta
Wed 3/257:00 pm
GNV
-
TYS
1 stop4h 57m
Delta
Deal found 3/6$563
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:00 am
TYS
-
GNV
1 stop6h 04m
American Airlines
Wed 3/256:00 am
GNV
-
TYS
2 stops8h 24m
American Airlines
Deal found 3/6$588
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:47 pm
TYS
-
GNV
1 stop6h 38m
American Airlines
Thu 3/126:24 am
GNV
-
TYS
1 stop4h 56m
American Airlines
Deal found 3/5$871

Find flight deals from Knoxville to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$327
(American Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Gainesville Regional flights.
Search Deals
From Knoxville McGhee Tyson to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Wed 4/8

5:00 am-10:55 am

1 stop5h 55m

Gainesville Regional

Wed 4/15

7:59 pm-11:55 pm

1 stop3h 56m

$327
Quickest round-trip

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Wed 3/25

5:47 pm-10:27 pm

1 stop4h 40m

Gainesville Regional

Fri 3/27

7:45 pm-11:50 pm

1 stop4h 05m

$477

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 3/21

5:40 am-9:29 am

1 stop3h 49m

Gainesville Regional

Wed 3/25

7:00 pm-11:57 pm

1 stop4h 57m

$563

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 3/21

5:00 am-11:04 am

1 stop6h 04m

Gainesville Regional

Wed 3/25

6:00 am-2:24 pm

2 stops8h 24m

$588

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Sorted by cheapest first

Compare providers for flights from Knoxville to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Gainesville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Gainesville

What is the cheapest month to book a flight from Knoxville to Gainesville?

Currently, July is the cheapest month in which you can book a flight from Knoxville to Gainesville (average of $62). Flying from Knoxville to Gainesville in March is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated March 10, 2026.
See what other customers who have flown with Delta from Knoxville to Gainesville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Gainesville?

    For as low as $327, American Airlines can have you in Gainesville from Knoxville in 5h 55m. There are 434 mi between Knoxville and Gainesville.

  • What is the cheapest airline to fly from Knoxville to Gainesville round-trip?

    According to our current data, Delta ($228), offers the cheapest pricing from Knoxville to Gainesville.

  • Can I find deals for flights from Knoxville to Gainesville that include hotel bookings?

    Yes. In addition to deals on Knoxville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Gainesville.

  • Can I find deals for business class flights from Knoxville to Gainesville?

    Yes. Cheapflights offers flight deals from Knoxville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Gainesville?

    Currently, July is the cheapest month in which you can book a flight from Knoxville to Gainesville (average of $62). Flying from Knoxville to Gainesville in March is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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Top airline flying from Knoxville to Gainesville

Discover the top airline that operate flights from Knoxville to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$298FlexibilityNo cancel feeOn-timeN/A

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