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$180+ Cheap flights from Gainesville to Knoxville (GNV - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/21. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — TYS
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Gainesville to Knoxville

Cheapest flights from Gainesville to Knoxville
Explore the most affordable flight options available from Gainesville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:32 pm
GNV
-
TYS
1 stop4h 19m
American Airlines
Sat 8/17:48 pm
TYS
-
GNV
1 stop4h 11m
American Airlines
Deal found 4/27$359
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:39 am
GNV
-
TYS
2 stops7h 48m
American Airlines
Sat 10/1710:59 am
TYS
-
GNV
1 stop7h 04m
American Airlines
Deal found 4/27$364
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:32 pm
GNV
-
TYS
1 stop4h 19m
American Airlines
Mon 8/35:03 am
TYS
-
GNV
1 stop4h 02m
American Airlines
Deal found 4/24$417
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:04 pm
GNV
-
TYS
1 stop4h 53m
Delta
Sun 6/145:40 am
TYS
-
GNV
1 stop3h 50m
Delta
Deal found 4/27$439
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:13 am
GNV
-
TYS
1 stop4h 20m
Delta
Tue 5/127:27 am
TYS
-
GNV
1 stop4h 55m
Delta
Deal found 4/23$447
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:25 am
GNV
-
TYS
2 stops11h 14m
American Airlines
Sat 5/165:00 am
TYS
-
GNV
1 stop5h 57m
American Airlines
Deal found 4/27$452
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:05 pm
GNV
-
TYS
1 stop4h 42m
Delta
Sun 9/205:30 am
TYS
-
GNV
1 stop3h 52m
Delta
Deal found 4/27$478

Find flight deals from Gainesville to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Delta)

One-way from

$180
(Delta)

Popular in

April

Cheapest in

January

Average price

$737
Provider with most accurate pricing for Gainesville Regional-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Knoxville McGhee Tyson flights.
Search Deals
From Gainesville Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Gainesville Regional to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($134 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sun 6/28

6:33 am-11:09 am

1 stop4h 36m

Knoxville McGhee Tyson

Thu 7/2

5:40 am-9:30 am

1 stop3h 50m

$359

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 7/25

7:32 pm-11:51 pm

1 stop4h 19m

Knoxville McGhee Tyson

Sat 8/1

8:05 pm-12:16 am

1 stop4h 11m

$359

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 7/30

7:32 pm-11:51 pm

1 stop4h 19m

Knoxville McGhee Tyson

Mon 8/3

5:03 am-9:05 am

1 stop4h 02m

$417

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 6/11

7:04 pm-11:57 pm

1 stop4h 53m

Knoxville McGhee Tyson

Sun 6/14

5:40 am-9:30 am

1 stop3h 50m

$439

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Fri 5/8

10:13 am-2:33 pm

1 stop4h 20m

Knoxville McGhee Tyson

Tue 5/12

7:27 am-12:22 pm

1 stop4h 55m

$447
Quickest round-trip

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 5/12

6:38 am-11:09 am

1 stop4h 31m

Knoxville McGhee Tyson

Sat 5/16

5:40 am-9:25 am

1 stop3h 45m

$447

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Fri 9/18

7:05 pm-11:47 pm

1 stop4h 42m

Knoxville McGhee Tyson

Sun 9/20

5:30 am-9:22 am

1 stop3h 52m

$478
Cheapest one-way
Quickest one-way

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sun 6/21

7:04 pm-11:54 pm

1 stop4h 50m

$180

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 5/14

7:05 pm-11:56 pm

1 stop4h 51m

$280

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 5/13

3:40 pm-9:48 pm

1 stop6h 08m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Sorted by cheapest first

Compare providers for flights from Gainesville to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Knoxville

What is the cheapest month to book a flight from Gainesville to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $228). Flying from Gainesville to Knoxville in April is currently the most expensive (average of $737). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Gainesville to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 28, 2026.
Read through reviews of airlines operating flights from Gainesville to Knoxville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,467 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,467 reviews
Delta
7.9
Good
8,467 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.1
Good
11,677 reviews
Delta
7.9
Good
8,467 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Knoxville?

    Airlines like Delta and American Airlines fly from Gainesville to Knoxville in about 4h 19m. The time it takes to get you to your destination can typically vary by up to 17m. The distance between Gainesville and Knoxville is about 434 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to Knoxville round-trip?

    Our cheapest airline available from Gainesville to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $228 on this airline. An additional option worth looking into is Delta, starting at $228. You may be able to fly from Gainesville to Knoxville for 43% less than the average price by searching for these airlines.

  • Can I find deals for flights from Gainesville to Knoxville that include hotel bookings?

    Yes. In addition to deals on Gainesville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Knoxville.

  • Can I find deals for business class flights from Gainesville to Knoxville?

    Yes. Cheapflights offers flight deals from Gainesville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $228). Flying from Gainesville to Knoxville in April is currently the most expensive (average of $737). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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Top 2 airlines flying from Gainesville to Knoxville

Discover the top 2 airlines that operate flights from Gainesville to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$313FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$435FlexibilityNo cancel feeOn-timeN/A

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