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Knoxville

$207+ Cheap flights from Gainesville to Knoxville (GNV - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — TYS
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
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Cheap flight deals from Gainesville to Knoxville

Cheapest flights from Gainesville to Knoxville
Explore the most affordable flight options available from Gainesville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:18 am
GNV
-
TYS
1 stop4h 22m
Delta
Tue 9/2910:26 am
TYS
-
GNV
1 stop4h 40m
Delta
Deal found 7/27$363
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:57 pm
GNV
-
TYS
1 stop3h 30m
Delta
Sun 9/135:40 am
TYS
-
GNV
1 stop3h 51m
Delta
Deal found 7/28$369
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am
GNV
-
TYS
2 stops7h 33m
American Airlines
Tue 9/296:15 am
TYS
-
GNV
1 stop4h 04m
American Airlines
Deal found 7/27$446
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:25 am
GNV
-
TYS
2 stops6h 17m
American Airlines
Thu 11/197:16 pm
TYS
-
GNV
1 stop4h 42m
American Airlines
Deal found 7/29$452
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:45 am
GNV
-
TYS
1 stop5h 59m
American Airlines
Sat 8/156:05 pm
TYS
-
GNV
1 stop3h 40m
American Airlines
Deal found 7/26$457
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:33 am
GNV
-
TYS
1 stop4h 08m
American Airlines
Fri 9/186:15 am
TYS
-
GNV
1 stop4h 04m
American Airlines
Deal found 7/25$546
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:45 am
GNV
-
TYS
1 stop6h 52m
American Airlines
Mon 8/177:23 pm
TYS
-
GNV
1 stop4h 36m
American Airlines
Deal found 7/26$585
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:41 pm
GNV
-
TYS
1 stop5h 54m
Delta
Mon 8/35:40 am
TYS
-
GNV
1 stop3h 43m
Delta
Deal found 7/28$587
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:15 am
GNV
-
TYS
2 stops9h 42m
American Airlines
Sun 8/163:41 pm
TYS
-
GNV
2 stops8h 18m
American Airlines
Deal found 7/28$626
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
GNV
-
TYS
2 stops9h 42m
American Airlines
Mon 8/36:07 pm
TYS
-
GNV
1 stop6h 09m
American Airlines
Deal found 7/26$640

Find flight deals from Gainesville to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$363
(Delta)

One-way from

$207
(Delta)

Popular in

July

Cheapest in

January

Average price

$743
Provider with most accurate pricing for Gainesville Regional-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Knoxville McGhee Tyson flights.
Search Deals
From Gainesville Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Gainesville Regional to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($94 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 9/26

10:18 am-2:40 pm

1 stop4h 22m

Knoxville McGhee Tyson

Tue 9/29

10:26 am-3:06 pm

1 stop4h 40m

$363

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 11/11

5:56 am-11:55 am

1 stop5h 59m

Knoxville McGhee Tyson

Thu 11/19

7:16 pm-11:58 pm

1 stop4h 42m

$363
Quickest round-trip

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Fri 9/11

6:57 pm-10:27 pm

1 stop3h 30m

Knoxville McGhee Tyson

Sun 9/13

5:40 am-9:31 am

1 stop3h 51m

$369

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 9/26

6:00 am-1:33 pm

2 stops7h 33m

Knoxville McGhee Tyson

Tue 9/29

6:15 am-10:19 am

1 stop4h 04m

$446

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 8/12

3:41 pm-6:56 pm

1 stop3h 15m

Knoxville McGhee Tyson

Sun 8/16

10:43 am-2:54 pm

1 stop4h 11m

$457

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 8/12

6:15 am-3:57 pm

2 stops9h 42m

Knoxville McGhee Tyson

Sun 8/16

5:00 am-9:14 am

1 stop4h 14m

$496

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 9/16

7:33 am-11:41 am

1 stop4h 08m

Knoxville McGhee Tyson

Fri 9/18

6:15 am-10:19 am

1 stop4h 04m

$546

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sun 8/16

5:45 am-12:37 pm

1 stop6h 52m

Knoxville McGhee Tyson

Mon 8/17

7:23 pm-11:59 pm

1 stop4h 36m

$585
Cheapest one-way
Quickest one-way

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Fri 9/11

6:57 pm-10:27 pm

1 stop3h 30m

$207

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sat 9/12

4:39 pm-9:06 pm

1 stop4h 27m

$207

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Gainesville to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to Knoxville in July.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Knoxville

How much does it cost to fly round-trip from Gainesville to Knoxville?

Airfare is typical for this route at the moment.

Gainesville to Knoxville flights typically cost between $297 and $386 in September.
The cheapest round-trip price found within the last 5 days was $363 on American Airlines (Sep 12-Sep 16).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 30, 2026.
Read through reviews of airlines operating flights from Gainesville to Knoxville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,486 reviews

Entertainment

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Comfort

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.8
Good
8,486 reviews
Delta
7.8
Good
8,486 reviews

Entertainment

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Comfort

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.1
Good
11,839 reviews
Delta
7.8
Good
8,486 reviews

Entertainment

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Comfort

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Knoxville?

    Airlines like Delta and American Airlines fly from Gainesville to Knoxville in about 4h 22m. The time it takes to get you to your destination can typically vary by up to 1h 37m. The distance between Gainesville and Knoxville is about 434 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to Knoxville round-trip?

    Our cheapest airline available from Gainesville to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $228 on this airline. An additional option worth looking into is Delta, starting at $228. You may be able to fly from Gainesville to Knoxville for 46% less than the average price by searching for these airlines.

  • Can I find deals for flights from Gainesville to Knoxville that include hotel bookings?

    Yes. In addition to deals on Gainesville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Knoxville.

  • Can I find deals for business class flights from Gainesville to Knoxville?

    Yes. Cheapflights offers flight deals from Gainesville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

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Top 2 airlines flying from Gainesville to Knoxville

Discover the top 2 airlines that operate flights from Gainesville to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$386FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$402FlexibilityNo cancel feeOn-timeN/A

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