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$268+ Cheap flights from Knoxville to Gainesville (TYS - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GNV
Jul 14 — Jul 211
Tue 7/14
Tue 7/21
1 adult, Economy
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Cheap flight deals from Knoxville to Gainesville

Cheapest flights from Knoxville to Gainesville
Explore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.

This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:59 pm
TYS
-
GNV
1 stop4h 16m
Delta
Mon 7/133:41 pm
GNV
-
TYS
1 stop5h 54m
Delta
Deal found 6/10$359
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
TYS
-
GNV
1 stop3h 30m
Delta
Fri 7/1010:17 am
GNV
-
TYS
1 stop4h 31m
Delta
Deal found 6/10$373
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:40 pm
TYS
-
GNV
1 stop4h 19m
American Airlines
Tue 9/86:39 pm
GNV
-
TYS
1 stop4h 19m
American Airlines
Deal found 6/12$381
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:59 pm
TYS
-
GNV
1 stop4h 34m
American Airlines
Thu 7/97:32 pm
GNV
-
TYS
1 stop4h 19m
American Airlines
Deal found 6/12$417
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:40 am
TYS
-
GNV
1 stop3h 50m
Delta
Tue 6/306:33 am
GNV
-
TYS
1 stop4h 36m
Delta
Deal found 6/11$447
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:56 am
TYS
-
GNV
1 stop4h 24m
American Airlines
Thu 7/167:32 pm
GNV
-
TYS
1 stop4h 19m
American Airlines
Deal found 6/11$481
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:59 pm
TYS
-
GNV
1 stop4h 34m
American Airlines
Tue 6/306:30 am
GNV
-
TYS
2 stops8h 45m
American Airlines
Deal found 6/11$486
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1911:55 am
TYS
-
GNV
1 stop3h 05m
Delta
Tue 6/236:33 am
GNV
-
TYS
1 stop3h 05m
Delta
Deal found 6/9$507
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:00 am
TYS
-
GNV
1 stop4h 05m
American Airlines
Mon 7/136:00 am
GNV
-
TYS
2 stops6h 34m
American Airlines
Deal found 6/10$529
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:00 am
TYS
-
GNV
1 stop4h 05m
American Airlines
Fri 7/106:00 am
GNV
-
TYS
2 stops9h 42m
American Airlines
Deal found 6/10$543

Find flight deals from Knoxville to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Delta)

One-way from

$268
(Delta)
Provider with most accurate pricing for Knoxville McGhee Tyson-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Gainesville Regional flights.
Search Deals
From Knoxville McGhee Tyson to Gainesville Regional
Search Deals
One-way flight from Knoxville McGhee Tyson to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 7/10

1:59 pm-6:15 pm

1 stop4h 16m

Gainesville Regional

Sun 7/12

3:41 pm-9:35 pm

1 stop5h 54m

$359

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 7/10

1:59 pm-6:15 pm

1 stop4h 16m

Gainesville Regional

Mon 7/13

3:41 pm-9:35 pm

1 stop5h 54m

$359

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 7/4

6:00 am-9:30 am

1 stop3h 30m

Gainesville Regional

Fri 7/10

10:17 am-2:48 pm

1 stop4h 31m

$373

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 9/5

7:40 pm-11:59 pm

1 stop4h 19m

Gainesville Regional

Tue 9/8

6:39 pm-10:58 pm

1 stop4h 19m

$381

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 6/26

7:59 pm-12:33 am

1 stop4h 34m

Gainesville Regional

Thu 7/9

7:32 pm-11:51 pm

1 stop4h 19m

$417

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 6/26

5:40 am-9:30 am

1 stop3h 50m

Gainesville Regional

Tue 6/30

6:33 am-11:09 am

1 stop4h 36m

$447

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 7/4

7:48 pm-11:59 pm

1 stop4h 11m

Gainesville Regional

Fri 7/10

6:00 am-3:42 pm

2 stops9h 42m

$543
Quickest round-trip

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Mon 7/6

5:40 am-9:30 am

1 stop3h 50m

Gainesville Regional

Thu 7/9

6:33 am-9:36 am

1 stop3h 03m

$575

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Tue 6/30

5:40 am-9:30 am

1 stop3h 50m

Gainesville Regional

Tue 6/30

5:22 pm-9:49 pm

1 stop4h 27m

$635
Cheapest one-way
Quickest one-way

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sun 7/12

5:40 am-9:28 am

1 stop3h 48m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Sorted by cheapest first

Compare providers for flights from Knoxville to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Gainesville in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Gainesville?

    For as low as $359, Delta can have you in Gainesville from Knoxville in 4h 16m. There are 434 mi between Knoxville and Gainesville. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to Gainesville that include hotel bookings?

    Yes. In addition to deals on Knoxville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Gainesville.

  • Can I find deals for business class flights from Knoxville to Gainesville?

    Yes. Cheapflights offers flight deals from Knoxville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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