$273+ Cheap flights from Knoxville to Gainesville (TYS - GNV)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GNV
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Gainesville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Gainesville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to GainesvilleExplore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Knoxville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:41 pm
TYS
- GNV
1 stop3h 07m
Delta
Sun 8/237:01 pm
GNV
- TYS
1 stop4h 51m
Delta
Deal found 7/27![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:15 am
TYS
- GNV
1 stop4h 54m
American Airlines
Wed 8/1210:44 am
GNV
- TYS
1 stop5h 13m
American Airlines
Deal found 7/24![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:53 pm
TYS
- GNV
1 stop3h 35m
American Airlines
Sun 10/117:34 pm
GNV
- TYS
1 stop4h 21m
American Airlines
Deal found 7/25![American Airlines logo]()
$477
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
TYS
- GNV
1 stop3h 18m
Delta
Wed 8/51:08 pm
GNV
- TYS
1 stop4h 11m
Delta
Deal found 7/25![Delta logo]()
$513
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:22 pm
TYS
- GNV
2 stops7h 37m
American Airlines
Sun 8/235:45 am
GNV
- TYS
1 stop6h 52m
American Airlines
Deal found 7/27![American Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:52 pm
TYS
- GNV
1 stop5h 34m
American Airlines
Sun 10/117:34 pm
GNV
- TYS
1 stop4h 21m
American Airlines
Deal found 7/25![American Airlines logo]()
$606
Best flights from Knoxville to GainesvilleDiscover carefully curated flight deals from Knoxville to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Knoxville to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:41 pm
TYS
- GNV
1 stop3h 07m
Delta
Sun 8/237:01 pm
GNV
- TYS
1 stop4h 51m
Delta
Deal found 7/27![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:15 am
TYS
- GNV
1 stop4h 54m
American Airlines
Wed 8/1210:44 am
GNV
- TYS
1 stop5h 13m
American Airlines
Deal found 7/24![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:53 pm
TYS
- GNV
1 stop3h 35m
American Airlines
Sun 10/117:34 pm
GNV
- TYS
1 stop4h 21m
American Airlines
Deal found 7/25![American Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:41 pm
TYS
- GNV
2 stops8h 18m
American Airlines
Sat 10/245:00 pm
GNV
- TYS
1 stop4h 49m
American Airlines
Deal found 7/28![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:52 pm
TYS
- GNV
1 stop5h 34m
American Airlines
Sun 10/117:34 pm
GNV
- TYS
1 stop4h 21m
American Airlines
Deal found 7/25![American Airlines logo]()
$606
Last-minute flights from Knoxville to GainesvilleDiscover last-minute flight deals from Knoxville to Gainesville. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Gainesville. Data last updated July 29, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
TYS
- GNV
1 stop3h 18m
Delta
Wed 8/51:08 pm
GNV
- TYS
1 stop4h 11m
Delta
Deal found 7/25![Delta logo]()
$513
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:15 am
TYS
- GNV
1 stop4h 54m
American Airlines
Wed 8/1210:44 am
GNV
- TYS
1 stop5h 13m
American Airlines
Deal found 7/24![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:41 pm
TYS
- GNV
1 stop3h 07m
Delta
Sun 8/237:01 pm
GNV
- TYS
1 stop4h 51m
Delta
Deal found 7/27![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:22 pm
TYS
- GNV
2 stops7h 37m
American Airlines
Sun 8/235:45 am
GNV
- TYS
1 stop6h 52m
American Airlines
Deal found 7/27![American Airlines logo]()
$556
One-way flights from Knoxville to GainesvilleSearch for one-way flight options from Knoxville to Gainesville. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Knoxville to Gainesville. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:06 pm
TYS
- GNV
1 stop3h 44m
American Airlines
Deal found 7/29![American Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:12 pm
TYS
- GNV
1 stop4h 36m
Delta
Deal found 7/28![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:00 pm
TYS
- GNV
2 stops10h 59m
American Airlines
Deal found 7/28![American Airlines logo]()
$455
Find flight deals from Knoxville to Gainesville
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $397 (Delta) |
One-way from | $273 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Fri 8/21
7:41 pm-10:48 pm
1 stop3h 07m
Gainesville Regional
Sun 8/23
7:01 pm-11:52 pm
1 stop4h 51m
$397
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Sat 8/8
5:15 am-10:09 am
1 stop4h 54m
Gainesville Regional
Wed 8/12
10:44 am-3:57 pm
1 stop5h 13m
$457
Quickest round-trip
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Sat 10/10
12:53 pm-4:28 pm
1 stop3h 35m
Gainesville Regional
Sun 10/11
7:34 pm-11:55 pm
1 stop4h 21m
$477
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Thu 10/22
3:41 pm-11:59 pm
2 stops8h 18m
Gainesville Regional
Sat 10/24
5:00 pm-9:49 pm
1 stop4h 49m
$542
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Fri 10/9
4:52 pm-10:26 pm
1 stop5h 34m
Gainesville Regional
Sun 10/11
7:34 pm-11:55 pm
1 stop4h 21m
$606
Cheapest one-way
Quickest one-way
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Thu 9/17
6:06 pm-9:50 pm
1 stop3h 44m
$273
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Mon 8/3
6:12 pm-10:48 pm
1 stop4h 36m
$448
KnoxvilleGainesville
TYS - GNV
TYSGNV
Knoxville McGhee Tyson
Mon 8/3
1:00 pm-11:59 pm
2 stops10h 59m
$455
Sorted by cheapest first
Compare providers for flights from Knoxville to Gainesville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Gainesville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Gainesville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Gainesville
Have a flexible travel schedule? Discover the best time to fly to Gainesville from Knoxville with our price prediction graph.
TYS-GNV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Gainesville
Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated July 29, 2026.
See what other customers who have flown with Delta from Knoxville to Gainesville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Gainesville?
Book flights to Gainesville if you plan to visit one of these locationsLake City
Alachua
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Top airline flying from Knoxville to Gainesville
Discover the top airline that operate flights from Knoxville to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$278 | FlexibilityNo cancel fee | On-timeN/A |