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$88+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Find cheap flights from Des Moines to Fort Myers with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in December or October, booked 12 days in advance, depart on a Monday or Tuesday and return on a Monday

Cheap flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
DSM
-
RSW
Nonstop3h 04m
Multiple Airlines
Sat 4/47:24 pm
RSW
-
DSM
1 stop19h 22m
Multiple Airlines
Deal found 1/27$177
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:00 am
DSM
-
RSW
Nonstop3h 04m
Allegiant Air
Fri 2/2010:54 am
RSW
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/27$201
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
DSM
-
RSW
Nonstop3h 04m
Allegiant Air
Fri 4/310:54 am
RSW
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/27$207
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
DSM
-
RSW
Nonstop3h 04m
Allegiant Air
Fri 3/610:54 am
RSW
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/26$212
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
DSM
-
RSW
Nonstop3h 04m
Multiple Airlines
Wed 3/44:25 pm
RSW
-
DSM
2 stops27h 17m
Multiple Airlines
Deal found 1/26$213
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/22:08 pm
DSM
-
RSW
Nonstop3h 04m
Allegiant Air
Fri 2/67:02 pm
RSW
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/27$226
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:59 pm
DSM
-
RSW
2 stops15h 02m
Multiple Airlines
Fri 3/610:54 am
RSW
-
DSM
Nonstop3h 19m
Multiple Airlines
Deal found 1/26$227
This Booking.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
DSM
-
RSW
Nonstop3h 04m
Allegiant Air
Mon 4/2710:54 am
RSW
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/28$228
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
DSM
-
RSW
Nonstop3h 04m
Multiple Airlines
Mon 3/239:54 pm
RSW
-
DSM
3 stops46h 22m
Multiple Airlines
Deal found 1/27$231
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
DSM
-
RSW
Nonstop3h 04m
Multiple Airlines
Wed 3/257:27 pm
RSW
-
DSM
2 stops19h 02m
Multiple Airlines
Deal found 1/28$234
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:27 pm
DSM
-
RSW
2 stops15h 34m
Multiple Airlines
Fri 3/610:54 am
RSW
-
DSM
Nonstop3h 19m
Multiple Airlines
Deal found 1/26$245

Find flight deals from Des Moines to Fort Myers

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$177
(Kiwi.com)

One-way from

$88
(Kiwi.com)

Popular in

March

Cheapest in

December

Average price

$381
Provider with most accurate pricing for Des Moines-Fort Myers SW Florida Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Fort Myers SW Florida Intl flights.
Search Deals
From Des Moines to Fort Myers SW Florida Intl
Search Deals
One-way flight from Des Moines to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Des Moines

Fly to

Fort Myers

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 3/1

5:15 pm-11:17 pm

1 stop5h 02m

Fort Myers SW Florida Intl

Wed 3/4

5:35 am-11:19 am

1 stop6h 44m

$261

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 3/2

7:17 pm-9:20 pm

3 stops25h 03m

Fort Myers SW Florida Intl

Fri 3/13

10:54 am-1:13 pm

Nonstop3h 19m

$280

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 3/3

5:15 pm-12:33 am

1 stop6h 18m

Fort Myers SW Florida Intl

Tue 3/10

5:59 pm-10:38 pm

1 stop5h 39m

$298

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 3/3

7:35 am-6:24 pm

1 stop9h 49m

Fort Myers SW Florida Intl

Wed 3/11

6:32 am-10:48 am

1 stop5h 16m

$298

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 3/4

12:04 pm-8:43 pm

1 stop7h 39m

Fort Myers SW Florida Intl

Wed 3/11

10:00 am-4:54 pm

1 stop7h 54m

$298

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 3/1

7:27 pm-12:01 pm

2 stops15h 34m

Fort Myers SW Florida Intl

Fri 3/13

10:54 am-1:13 pm

Nonstop3h 19m

$300

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 3/2

5:15 pm-12:33 am

1 stop6h 18m

Fort Myers SW Florida Intl

Thu 3/12

10:00 am-4:54 pm

1 stop7h 54m

$310

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 3/4

5:15 pm-12:33 am

1 stop6h 18m

Fort Myers SW Florida Intl

Thu 3/12

10:00 am-4:54 pm

1 stop7h 54m

$310

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 3/3

12:25 pm-9:48 pm

1 stop8h 23m

Fort Myers SW Florida Intl

Thu 3/5

6:25 pm-10:28 pm

1 stop5h 03m

$310

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 3/3

3:20 pm-9:35 pm

1 stop5h 15m

Fort Myers SW Florida Intl

Mon 3/9

12:40 pm-11:15 pm

2 stops11h 35m

$315

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 20 results
1
2

Compare providers for flights from Des Moines to Fort Myers

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Fort Myers. Price data was last updated on January 23, 2026.

The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 12 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Fort Myers?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $85). Flying from Des Moines to Fort Myers in September is currently the most expensive (average of $147). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to RSW?

Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

When flying from Des Moines to Fort Myers, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Fort Myers

Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,127 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,206 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Allegiant Air
7.2
Good
706 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Fort Myers flight route?

    Within the past month, 1 users have taken a look at flights from Des Moines to Fort Myers SW Florida Intl.

  • How long is the flight from Des Moines to Fort Myers?

    A quick flight from Des Moines to Fort Myers can take about 5h 02m. Delta provides one of the quickest options available for as low as $261. The distance from Des Moines to Fort Myers is about 1237 mi.

  • What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

    Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $92. Other airlines that can offer you cheap pricing are Delta, from $203, and United Airlines, from $260. Allegiant Air is currently priced 74% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Fort Myers one-way?

    One-way options have recently been found by users for as low as $88 on Allegiant Air. Other airlines that offer cheap prices include American Airlines from $125 and Southwest from $130 one-way.

  • What are the cheapest flights from Des Moines to Fort Myers?

    The cheapest flight price from Des Moines to Fort Myers is $88. On average you can expect to pay $311. The most popular route, (Des Moines - Fort Myers SW Florida Intl), can usually be booked for $122.

  • Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.

  • Can I find deals for business class flights from Des Moines to Fort Myers?

    Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Fort Myers?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $85). Flying from Des Moines to Fort Myers in September is currently the most expensive (average of $147). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sanibel
North Fort Myers
Estero
Lehigh Acres

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Top 5 airlines flying from Des Moines to Fort Myers

Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$92Average$218FlexibilityNo cancel feeOn-time88%
DeltaCheapest$203Average$386FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$260Average$360FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$276Average$387FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$300Average$407FlexibilityNo cancel feeOn-time63%

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