$41+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Apr 12 — Apr 191
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Fort Myers with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in April or January, booked 19 days in advance, depart on a Monday or Tuesday and return on a Monday
Cheap flight deals from Des Moines to Fort Myers
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Best
Last-minute
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Cheapest flights from Des Moines to Fort MyersExplore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 5/1110:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/9![Allegiant Air logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Wed 4/87:24 pm
RSW
- DSM
1 stop19h 22m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Sat 4/117:24 pm
RSW
- DSM
1 stop19h 22m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 3/3010:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/10![Allegiant Air logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Thu 5/711:40 am
RSW
- DSM
2 stops26h 49m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$242
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Thu 3/265:28 pm
RSW
- DSM
1 stop26h 48m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Fri 3/2710:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/13![Allegiant Air logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Tue 4/149:54 pm
RSW
- DSM
2 stops43h 06m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$254
This Mytrip deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 5/410:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/9![Allegiant Air logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 4/2010:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/9![Allegiant Air logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 4/1310:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/10![Allegiant Air logo]()
$275
Best flights from Des Moines to Fort MyersDiscover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:20 pm
DSM
- RSW
1 stop5h 20m
Southwest
Tue 5/197:00 am
RSW
- DSM
1 stop5h 25m
Southwest
Deal found 3/12![Southwest logo]()
$360
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:04 am
DSM
- RSW
2 stops11h 35m
United Airlines
Mon 4/206:20 pm
RSW
- DSM
1 stop5h 57m
United Airlines
Deal found 3/12![United Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:51 am
DSM
- RSW
1 stop8h 00m
Delta
Sat 3/286:32 am
RSW
- DSM
1 stop5h 16m
Delta
Deal found 3/8![Delta logo]()
$487
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:20 pm
DSM
- RSW
1 stop5h 20m
Southwest
Wed 4/296:05 am
RSW
- DSM
2 stops9h 00m
Southwest
Deal found 3/9![Southwest logo]()
$365
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:35 am
DSM
- RSW
2 stops9h 40m
Southwest
Wed 5/66:05 am
RSW
- DSM
2 stops9h 00m
Southwest
Deal found 3/10![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:00 am
DSM
- RSW
1 stop8h 44m
United Airlines
Sat 5/305:00 pm
RSW
- DSM
1 stop6h 35m
United Airlines
Deal found 3/9![United Airlines logo]()
$461
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:35 am
DSM
- RSW
1 stop6h 22m
Delta
Tue 4/75:59 pm
RSW
- DSM
1 stop5h 39m
Delta
Deal found 3/12![Delta logo]()
$523
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:30 am
DSM
- RSW
2 stops9h 15m
United Airlines
Sat 3/284:59 pm
RSW
- DSM
1 stop6h 45m
United Airlines
Deal found 3/8![United Airlines logo]()
$492
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:50 am
DSM
- RSW
2 stops15h 30m
Southwest
Tue 3/3111:35 am
RSW
- DSM
2 stops11h 30m
Southwest
Deal found 3/12![Southwest logo]()
$553
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/232:04 pm
DSM
- RSW
1 stop7h 16m
United Airlines
Fri 3/276:45 am
RSW
- DSM
2 stops10h 22m
United Airlines
Deal found 3/8![United Airlines logo]()
$568
Last-minute flights from Des Moines to Fort MyersDiscover last-minute flight deals from Des Moines to Fort Myers. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Fort Myers. Data last updated March 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Mon 3/239:39 pm
RSW
- DSM
3 stops46h 37m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 3/3010:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/10![Allegiant Air logo]()
$231
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Thu 3/265:28 pm
RSW
- DSM
1 stop26h 48m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Fri 3/2710:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/13![Allegiant Air logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:00 am
DSM
- RSW
1 stop10h 19m
Multiple Airlines
Sat 4/117:24 pm
RSW
- DSM
1 stop19h 22m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Wed 4/87:24 pm
RSW
- DSM
1 stop19h 22m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Sat 4/117:24 pm
RSW
- DSM
1 stop19h 22m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Tue 4/149:54 pm
RSW
- DSM
2 stops43h 06m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 4/1310:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/10![Allegiant Air logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Multiple Airlines
Mon 4/135:45 am
RSW
- DSM
2 stops14h 29m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Mon 4/2010:54 am
RSW
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/9![Allegiant Air logo]()
$272
One-way flights from Des Moines to Fort MyersSearch for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Deal found 3/13![Allegiant Air logo]()
$41
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Deal found 3/11![Allegiant Air logo]()
$54
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Deal found 3/11![Allegiant Air logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Deal found 3/11![Allegiant Air logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Deal found 3/11![Allegiant Air logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Deal found 3/12![Allegiant Air logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:00 am
DSM
- RSW
1 stop10h 19m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$115
This Super.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:00 am
DSM
- RSW
Nonstop3h 04m
Allegiant Air
Deal found 3/11![Allegiant Air logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:00 am
DSM
- RSW
1 stop10h 19m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:00 am
DSM
- RSW
1 stop29h 10m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$138
Find flight deals from Des Moines to Fort Myers
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $146 (Kiwi.com) |
One-way from | $41 (Kiwi.com) |
Popular in | July |
Cheapest in | April |
Average price | $360 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Thu 5/14
4:20 pm-10:40 pm
1 stop5h 20m
Fort Myers SW Florida Intl
Tue 5/19
7:00 am-11:25 am
1 stop5h 25m
$360
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Thu 4/23
4:20 pm-10:40 pm
1 stop5h 20m
Fort Myers SW Florida Intl
Wed 4/29
6:05 am-2:05 pm
2 stops9h 00m
$365
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Sat 5/2
5:35 am-4:15 pm
2 stops9h 40m
Fort Myers SW Florida Intl
Wed 5/6
6:05 am-2:05 pm
2 stops9h 00m
$387
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Wed 4/15
8:04 am-8:39 pm
2 stops11h 35m
Fort Myers SW Florida Intl
Mon 4/20
6:20 pm-11:17 pm
1 stop5h 57m
$445
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Tue 5/26
5:00 am-2:44 pm
1 stop8h 44m
Fort Myers SW Florida Intl
Sat 5/30
5:00 pm-10:35 pm
1 stop6h 35m
$461
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Tue 3/24
10:51 am-7:51 pm
1 stop8h 00m
Fort Myers SW Florida Intl
Sat 3/28
6:32 am-10:48 am
1 stop5h 16m
$487
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Tue 3/24
5:30 am-3:45 pm
2 stops9h 15m
Fort Myers SW Florida Intl
Sat 3/28
4:59 pm-10:44 pm
1 stop6h 45m
$492
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Tue 3/31
5:35 am-12:57 pm
1 stop6h 22m
Fort Myers SW Florida Intl
Tue 4/7
5:59 pm-10:38 pm
1 stop5h 39m
$523
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Fri 3/27
6:50 am-11:20 pm
2 stops15h 30m
Fort Myers SW Florida Intl
Tue 3/31
11:35 am-10:05 pm
2 stops11h 30m
$553
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Mon 3/23
2:04 pm-10:20 pm
1 stop7h 16m
Fort Myers SW Florida Intl
Fri 3/27
6:45 am-4:07 pm
2 stops10h 22m
$568
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Fort Myers
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Fort Myers
Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
DSM-RSW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Fort Myers
How far ahead should I book a flight from Des Moines to Fort Myers?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Fort Myers. Price data was last updated on March 6, 2026.
The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 19 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Fort Myers?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $81). Flying from Des Moines to Fort Myers in March is currently the most expensive (average of $173). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to RSW?
Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 13, 2026.
When flying from Des Moines to Fort Myers, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Fort Myers
Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated March 13, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Fort Myers?
Book flights to Fort Myers if you plan to visit one of these locationsSanibel
North Fort Myers
Estero
Lehigh Acres
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Des Moines and Fort Myers flights
Browse other Des Moines and Fort Myers flight options. Last updated on March 13, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on March 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Des Moines to Fort Myers
Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$98 | Average$224 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$203 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$360 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$263 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$403 | FlexibilityNo cancel fee | On-time63% |