How long is the flight from Des Moines to Fort Myers?

A quick flight from Des Moines to Fort Myers can take about 5h. Delta provides one of the quickest options available for as low as $225. The distance from Des Moines to Fort Myers is about 1237 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $142. Other airlines that can offer you cheap pricing are Delta, from $263, and American Airlines, from $296. Allegiant Air is currently priced 64% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Des Moines to Fort Myers one-way?

One-way options have recently been found by users for as low as $115 on Delta. Other airlines that offer cheap prices include United Airlines from $115 and American Airlines from $115 one-way.

What is the cheapest day to fly from Des Moines to Fort Myers?

Travelers seeking maximum savings on their Des Moines to Fort Myers flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Fort Myers ranges from 1.7 - 10.1 inches per month. June is typically the wettest month, when rainfall can reach 10.1 in. December is typically the driest time to visit Fort Myers when rainfall is around 1.7 in.

If weather is an important factor for your trip to Fort Myers, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 64.4 F).

What are the most popular airlines that fly from Des Moines to Fort Myers?

When booking a flight from Des Moines to Fort Myers, you may want to consider flying on American Airlines, Delta or Allegiant Air as they are the most popular for this route.

What is the cheapest day to fly round-trip from Des Moines to Fort Myers?

Flying to your destination on a Saturday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Fort Myers. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Des Moines to Fort Myers?

Users have found that booking a flight from Des Moines to Fort Myers at least 59 days early can save you up to 116% on average compared to booking a flight this week. If booking 59 days before your flight isn’t an option for you, users have found flights from Des Moines to Fort Myers for as little as $296 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $780 for flights departing within the next 3 days.

What is the cheapest month to fly from Des Moines to Fort Myers?

August can be a great time to fly to Fort Myers from Des Moines with a flight ticket averaging about $402. Cheapflights users have found deals in the month of August for as cheap as $285. The most expensive prices can be found in the month of March.

Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Fort Myers?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.

Can I find deals for business class flights from Des Moines to Fort Myers?

Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$115+ Cheap Flights from Des Moines to Fort Myers

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Des Moines to Fort Myers with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in August or September, booked 59 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Des Moines to Fort Myers

Round-trip from	$118 (Kiwi.com)
One-way from	$115 (Delta)
Popular in	March
Cheapest in	August
Average price	$342

From Des Moines to Fort Myers SW Florida Intl

Search Deals

One-way flight from Des Moines to Fort Myers SW Florida Intl

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($73 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

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Find flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Mon 12/82:00 pmDSM - RSW

Nonstop3h 04mAllegiant Air

Fri 12/126:50 pmRSW - DSM

Nonstop3h 19mAllegiant Air

Deal found 9/10

$118

Sat 10/45:12 pmDSM - RSW

1 stop6h 22mDelta

Sat 10/115:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$217

Sat 11/17:25 amDSM - RSW

1 stop6h 50mSouthwest

Wed 11/512:30 pmRSW - DSM

1 stop8h 25mSouthwest

Deal found 9/9

$220

Sat 10/42:49 pmDSM - RSW

1 stop7h 18mDelta

Wed 10/87:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$223

Sat 10/45:12 pmDSM - RSW

1 stop6h 22mDelta

Thu 10/97:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$225

Tue 10/72:13 pmDSM - RSW

1 stop4h 38mDelta

Tue 10/142:50 pmRSW - DSM

1 stop7h 13mDelta

Deal found 9/10

$229

Mon 11/32:19 pmDSM - RSW

1 stop7h 56mAmerican Airlines

Sat 11/88:05 amRSW - DSM

2 stops8h 27mAmerican Airlines

Deal found 9/10

$230

Mon 10/65:32 pmDSM - RSW

1 stop5h 07mDelta

Wed 10/88:14 amRSW - DSM

1 stop6h 14mDelta

Deal found 9/10

$231

Mon 10/66:39 pmDSM - RSW

1 stop5h 00mDelta

Thu 10/97:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$233

Tue 9/309:34 amDSM - RSW

2 stops11h 59mAmerican Airlines

Tue 10/76:39 pmRSW - DSM

1 stop5h 29mAmerican Airlines

Deal found 9/9

$234

Fri 10/36:30 pmDSM - RSW

1 stop5h 05mDelta

Sat 10/117:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$238

Best flights from Des Moines to Fort Myers
Discover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Mon 10/66:39 pmDSM - RSW

1 stop5h 00mDelta

Sat 10/1112:31 pmRSW - DSM

1 stop5h 21mDelta

Deal found 9/10

$225

Wed 11/55:45 amDSM - RSW

1 stop8h 47mUnited Airlines

Sun 11/98:00 amRSW - DSM

1 stop9h 12mUnited Airlines

Deal found 9/10

$253

Wed 11/126:15 amDSM - RSW

1 stop4h 25mSouthwest

Sat 11/158:05 amRSW - DSM

1 stop7h 50mSouthwest

Deal found 9/9

$262

Tue 10/76:39 pmDSM - RSW

1 stop5h 00mDelta

Thu 10/95:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$231

Sun 11/27:20 amDSM - RSW

1 stop6h 59mDelta

Wed 11/55:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$253

Sun 11/27:20 amDSM - RSW

1 stop6h 59mDelta

Thu 11/66:58 amRSW - DSM

1 stop7h 30mDelta

Deal found 9/10

$255

Sun 11/27:20 amDSM - RSW

1 stop6h 59mDelta

Fri 11/75:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$268

Tue 11/1110:21 amDSM - RSW

1 stop5h 28mDelta

Fri 11/1410:30 amRSW - DSM

1 stop9h 48mDelta

Deal found 9/9

$277

Tue 11/112:17 pmDSM - RSW

1 stop6h 17mDelta

Sat 11/156:58 amRSW - DSM

1 stop4h 44mDelta

Deal found 9/9

$277

Thu 11/137:46 amDSM - RSW

1 stop9h 48mDelta

Sat 11/156:58 amRSW - DSM

1 stop4h 44mDelta

Deal found 9/9

$277

Thu 11/137:46 amDSM - RSW

1 stop9h 48mDelta

Sun 11/165:35 amRSW - DSM

1 stop6h 07mDelta

Deal found 9/9

$277

Last-minute flights from Des Moines to Fort Myers
Discover last-minute flight deals from Des Moines to Fort Myers. Data last updated September 11, 2025 and is based on user searches.

Fri 10/36:30 pmDSM - RSW

1 stop5h 05mDelta

Sat 10/117:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$238

Fri 10/36:30 pmDSM - RSW

1 stop5h 05mDelta

Wed 10/82:13 pmRSW - DSM

1 stop7h 22mDelta

Deal found 9/10

$244

Fri 10/311:25 amDSM - RSW

1 stop4h 45mDelta

Thu 10/97:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$246

Fri 10/311:25 amDSM - RSW

1 stop4h 45mDelta

Fri 10/102:13 pmRSW - DSM

1 stop7h 22mDelta

Deal found 9/10

$259

Sat 10/45:12 pmDSM - RSW

1 stop6h 22mDelta

Sat 10/115:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$217

Sat 10/42:49 pmDSM - RSW

1 stop7h 18mDelta

Wed 10/87:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$223

Sat 10/45:12 pmDSM - RSW

1 stop6h 22mDelta

Sun 10/125:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$251

Mon 10/66:39 pmDSM - RSW

1 stop5h 00mDelta

Sat 10/115:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/11

$225

Mon 10/66:39 pmDSM - RSW

1 stop5h 00mDelta

Tue 10/146:58 amRSW - DSM

1 stop7h 30mDelta

Deal found 9/10

$231

Mon 10/66:39 pmDSM - RSW

1 stop5h 00mDelta

Thu 10/97:45 amRSW - DSM

1 stop7h 14mDelta

Deal found 9/10

$233

Tue 10/72:13 pmDSM - RSW

1 stop4h 38mDelta

Wed 10/85:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$229

Tue 10/77:20 amDSM - RSW

1 stop6h 59mDelta

Sun 10/125:38 amRSW - DSM

1 stop5h 27mDelta

Deal found 9/10

$257

One-way flights from Des Moines to Fort Myers
Search for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Wed 11/56:39 pmDSM - RSW

1 stop5h 00mDelta

Deal found 9/11

$115

Mon 10/66:39 pmDSM - RSW

1 stop5h 00mDelta

Deal found 9/11

$117

Wed 11/58:02 amDSM - RSW

2 stops12h 34mUnited Airlines

Deal found 9/10

$120

Fri 10/106:39 pmDSM - RSW

1 stop5h 00mDelta

Deal found 9/11

$130

Thu 9/256:30 amDSM - RSW

2 stops10h 59mMultiple Airlines

Deal found 9/10

$133

Thu 11/1310:50 amDSM - RSW

2 stops20h 31mMultiple Airlines

Deal found 9/10

$134

Sun 10/1211:30 amDSM - RSW

1 stop9h 40mUnited Airlines

Deal found 9/10

$143

Mon 10/66:15 pmDSM - RSW

1 stop4h 30mSouthwest

Deal found 9/11

$157

Tue 10/75:00 amDSM - RSW

2 stops9h 54mAmerican Airlines

Deal found 9/11

$160

Thu 12/188:45 amDSM - RSW

1 stop7h 26mAmerican Airlines

Deal found 9/10

$168

Mon 10/611:25 amDSM - RSW

2 stops44h 23mMultiple Airlines

Deal found 9/11

$171

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 10/6

6:39 pm-12:39 am

1 stop5h 00m

Fort Myers SW Florida Intl

Sat 10/11

12:31 pm-4:52 pm

1 stop5h 21m

$225

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 10/7

6:39 pm-12:39 am

1 stop5h 00m

Fort Myers SW Florida Intl

Thu 10/9

5:38 am-10:05 am

1 stop5h 27m

$231

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 11/5

5:45 am-3:32 pm

1 stop8h 47m

Fort Myers SW Florida Intl

Sun 11/9

8:00 am-4:12 pm

1 stop9h 12m

$253

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 11/2

7:20 am-3:19 pm

1 stop6h 59m

Fort Myers SW Florida Intl

Wed 11/5

5:38 am-10:05 am

1 stop5h 27m

$253

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 11/2

7:20 am-3:19 pm

1 stop6h 59m

Fort Myers SW Florida Intl

Thu 11/6

6:58 am-1:28 pm

1 stop7h 30m

$255

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 11/12

6:15 am-11:40 am

1 stop4h 25m

Fort Myers SW Florida Intl

Sat 11/15

8:05 am-2:55 pm

1 stop7h 50m

$262

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 11/2

7:20 am-3:19 pm

1 stop6h 59m

Fort Myers SW Florida Intl

Fri 11/7

5:38 am-10:05 am

1 stop5h 27m

$268

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 11/11

10:21 am-4:49 pm

1 stop5h 28m

Fort Myers SW Florida Intl

Fri 11/14

10:30 am-7:18 pm

1 stop9h 48m

$277

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 11/11

2:17 pm-9:34 pm

1 stop6h 17m

Fort Myers SW Florida Intl

Sat 11/15

6:58 am-10:42 am

1 stop4h 44m

$277

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 11/13

7:46 am-6:34 pm

1 stop9h 48m

Fort Myers SW Florida Intl

Sat 11/15

6:58 am-10:42 am

1 stop4h 44m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 16 results

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 58 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Fort Myers?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $205). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to RSW?

A simple way to save on the total cost of your ticket is to fly from Des Moines to Fort Myers at noon. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Fort Myers

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,248 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,248 reviews

Southwest

8.0

Very good

4,248 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Delta

8.0

Very good

7,960 reviews

Southwest

8.0

Very good

4,248 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

United Airlines

7.4

Good

8,937 reviews

Southwest

8.0

Very good

4,248 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,248 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Allegiant Air

7.2

Good

702 reviews

Southwest

8.0

Very good

4,248 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

How long is the flight from Des Moines to Fort Myers?
A quick flight from Des Moines to Fort Myers can take about 5h. Delta provides one of the quickest options available for as low as $225. The distance from Des Moines to Fort Myers is about 1237 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?
Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $142. Other airlines that can offer you cheap pricing are Delta, from $263, and American Airlines, from $296. Allegiant Air is currently priced 64% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Des Moines to Fort Myers one-way?
One-way options have recently been found by users for as low as $115 on Delta. Other airlines that offer cheap prices include United Airlines from $115 and American Airlines from $115 one-way.
Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?
Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Fort Myers?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.
Can I find deals for business class flights from Des Moines to Fort Myers?
Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Fort Myers?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $205). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Des Moines to Fort Myers

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$142	Average$296	FlexibilityNo cancel fee	On-time88%
Delta	Cheapest$263	Average$401	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$296	Average$392	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$301	Average$471	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$316	Average$449	FlexibilityNo cancel fee	On-time63%

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$115+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Fort Myers with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in August or September, booked 59 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Des Moines to Fort Myers

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort MyersExplore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

What is the cheapest month to book a flight from Des Moines to Fort Myers?

What is the cheapest time of day to fly from DSM to RSW?

Reviews of airlines servicing Fort Myers

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Des Moines to Fort Myers?

What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

What are the cheapest airlines to fly from Des Moines to Fort Myers one-way?

Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

How can I find direct flights from Des Moines to Fort Myers?

Can I find deals for business class flights from Des Moines to Fort Myers?

What is the cheapest month to book a flight from Des Moines to Fort Myers?

Traveling to a place near Fort Myers?

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Alternative routes for Des Moines to Fort Myers

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Top 5 airlines flying from Des Moines to Fort Myers

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Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.