HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Fort Myers

$99+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Fort Myers with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in August or September, booked 59 days in advance, depart on a Thursday or Monday and return on a Friday

Find flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:32 pmDSM - RSW
1 stop5h 05mDelta
Thu 11/276:55 amRSW - DSM
1 stop6h 20mDelta
Deal found 10/12$261
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/241:56 pmDSM - RSW
Nonstop3h 04mMultiple Airlines
Thu 11/271:38 pmRSW - DSM
3 stops30h 23mMultiple Airlines
Deal found 10/12$326
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:07 pmDSM - RSW
1 stop5h 33mAmerican Airlines
Mon 12/226:00 amRSW - DSM
1 stop8h 21mAmerican Airlines
Deal found 10/13$327
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:32 pmDSM - RSW
1 stop5h 03mDelta
Thu 11/276:55 amRSW - DSM
1 stop6h 20mDelta
Deal found 10/12$334
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:15 pmDSM - RSW
1 stop6h 24mDelta
Sat 11/156:55 amRSW - DSM
1 stop7h 37mDelta
Deal found 10/11$337
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:56 pmDSM - RSW
Nonstop3h 04mMultiple Airlines
Thu 11/271:38 pmRSW - DSM
2 stops30h 23mMultiple Airlines
Deal found 10/12$338
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:02 amDSM - RSW
1 stop5h 39mUnited Airlines
Sat 11/1512:39 pmRSW - DSM
2 stops12h 05mUnited Airlines
Deal found 10/11$342
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:19 pmDSM - RSW
2 stops9h 08mAmerican Airlines
Sat 11/156:00 amRSW - DSM
2 stops8h 16mAmerican Airlines
Deal found 10/11$347
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:35 pmDSM - RSW
1 stop8h 38mAmerican Airlines
Mon 12/225:27 pmRSW - DSM
1 stop7h 06mAmerican Airlines
Deal found 10/12$367
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1112:54 pmDSM - RSW
2 stops9h 35mAmerican Airlines
Sun 11/168:05 amRSW - DSM
1 stop6h 26mAmerican Airlines
Deal found 10/12$372
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:49 amDSM - RSW
1 stop6h 33mAmerican Airlines
Mon 11/107:01 amRSW - DSM
1 stop8h 30mAmerican Airlines
Deal found 10/11$377

Cheap flight deals from Des Moines to Fort Myers

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$187
(FlightHub)

One-way from

$99
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$318
Provider with most accurate pricing for Des Moines-Fort Myers SW Florida Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Fort Myers SW Florida Intl flights.
Search Deals
From Des Moines to Fort Myers SW Florida Intl
Search Deals
One-way flight from Des Moines to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Des Moines

Fly to

Fort Myers

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 1/20

10:55 am-5:12 pm

1 stop5h 17m

Fort Myers SW Florida Intl

Tue 1/27

5:35 am-10:23 am

1 stop5h 48m

$261

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 12/18

3:55 pm-12:28 am

2 stops7h 33m

Fort Myers SW Florida Intl

Mon 12/22

8:10 am-1:21 pm

1 stop6h 11m

$332

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 1/22

5:15 pm-12:37 am

1 stop6h 22m

Fort Myers SW Florida Intl

Sat 1/31

5:35 am-10:23 am

1 stop5h 48m

$332

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sun 11/23

6:32 pm-12:35 am

1 stop5h 03m

Fort Myers SW Florida Intl

Thu 11/27

6:55 am-12:15 pm

1 stop6h 20m

$334

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 1/22

8:35 am-9:30 pm

2 stops11h 55m

Fort Myers SW Florida Intl

Sat 1/31

6:25 am-2:55 pm

2 stops9h 30m

$342

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 1/22

11:42 am-11:33 pm

2 stops10h 51m

Fort Myers SW Florida Intl

Sat 1/31

3:07 pm-10:11 pm

2 stops8h 04m

$342

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 12/10

11:35 am-7:56 pm

1 stop7h 21m

Fort Myers SW Florida Intl

Sun 12/14

7:00 am-2:12 pm

1 stop8h 12m

$367

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 12/11

11:35 am-7:56 pm

1 stop7h 21m

Fort Myers SW Florida Intl

Sun 12/14

5:05 pm-10:29 pm

1 stop6h 24m

$367

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 11/14

7:46 am-6:34 pm

1 stop9h 48m

Fort Myers SW Florida Intl

Mon 11/17

6:55 am-1:32 pm

1 stop7h 37m

$367

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 1/17

8:10 am-3:48 pm

1 stop6h 38m

Fort Myers SW Florida Intl

Wed 1/21

9:20 am-2:33 pm

1 stop6h 13m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/10

Showing 1-10 of 20 results
1
2

Compare providers for flights from Des Moines to Fort Myers

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Fort Myers. Price data was last updated on October 10, 2025.

The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 58 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Fort Myers?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $90). Flying from Des Moines to Fort Myers in September is currently the most expensive (average of $147). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to RSW?

Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Fort Myers at noon. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Des Moines to Fort Myers?

Reviews of airlines servicing Fort Myers

Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated October 13, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,235 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,235 reviews
Southwest
8.0
Very good
4,235 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,973 reviews
Southwest
8.0
Very good
4,235 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,973 reviews
Southwest
8.0
Very good
4,235 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,045 reviews
Southwest
8.0
Very good
4,235 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Allegiant Air
7.2
Good
693 reviews
Southwest
8.0
Very good
4,235 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Fort Myers?

    A quick flight from Des Moines to Fort Myers can take about 5h 17m. Delta provides one of the quickest options available for as low as $261. The distance from Des Moines to Fort Myers is about 1237 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

    Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $142. Other airlines that can offer you cheap pricing are Delta, from $263, and American Airlines, from $276. Allegiant Air is currently priced 63% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Fort Myers one-way?

    One-way options have recently been found by users for as low as $99 on Allegiant Air. Other airlines that offer cheap prices include United Airlines from $131 and American Airlines from $164 one-way.

  • What are the cheapest flights from Des Moines to Fort Myers?

    The cheapest flight price from Des Moines to Fort Myers is $162. On average you can expect to pay $282. The most popular route, (Des Moines - Fort Myers SW Florida Intl), can usually be booked for $188.

  • Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.

  • Can I find deals for business class flights from Des Moines to Fort Myers?

    Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Fort Myers?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $90). Flying from Des Moines to Fort Myers in September is currently the most expensive (average of $147). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sanibel
North Fort Myers
Estero
Lehigh Acres

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Fort Myers

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Orlando flights
Cedar Rapids to Orlando flights
Des Moines to Miami flights
Des Moines to Orlando flights
Omaha to Miami flights
Moline to Orlando flights
Des Moines to Tampa flights
Omaha to Tampa flights
Cedar Rapids to Sarasota flights
Cedar Rapids to Tampa flights
Cedar Rapids to Miami flights
Omaha to Fort Lauderdale flights
Moline to Tampa flights
Omaha to Fort Myers flights
Cedar Rapids to Fort Lauderdale flights
Des Moines to Orlando Sanford Intl flights
Des Moines to Fort Lauderdale flights
Des Moines to Key West flights
Des Moines to Sarasota flights
Des Moines to Jacksonville flights
Cedar Rapids to Orlando Sanford Intl flights
Des Moines to Pensacola flights
Omaha to Sarasota flights
Omaha to Pensacola flights
Moline to Miami flights
Cedar Rapids to Key West flights
Des Moines to Valparaiso flights
Cedar Rapids to Fort Myers flights
Cedar Rapids to St Petersburg flights
Cedar Rapids to Jacksonville flights
Moline to St Petersburg flights
Omaha to Key West flights
Cedar Rapids to Panama City flights
Moline to Key West flights
Des Moines to St Petersburg flights
Moline to Pensacola flights
Moline to Fort Myers flights
Omaha to Orlando Sanford Intl flights
Moline to Fort Lauderdale flights
Omaha to Valparaiso flights
Cedar Rapids to Pensacola flights
Omaha to West Palm Beach flights
Cedar Rapids to Punta Gorda flights
Omaha to Jacksonville flights
Mason City to Orlando flights
Des Moines to West Palm Beach flights
Omaha to Panama City flights
Cedar Rapids to West Palm Beach flights
Omaha to St Petersburg flights

Top 5 airlines flying from Des Moines to Fort Myers

Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$142Average$282FlexibilityNo cancel feeOn-time88%
DeltaCheapest$263Average$400FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$276Average$388FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$297Average$424FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$310Average$432FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.