$38+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Fort Myers with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in September or January, booked 31 days in advance, depart on a Monday or Thursday and return on a Tuesday
Cheap flight deals from Des Moines to Fort Myers
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to Fort MyersExplore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This CheapOair deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/143:05 pm -
Nonstop2h 58m
Fri 1/810:45 am -
Nonstop3h 22m
Deal found 10/21![Allegiant Air logo]()
$86
This Super.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:04 pm -
Nonstop2h 59m
Fri 11/68:00 pm -
Nonstop3h 15m
Deal found 10/21![Allegiant Air logo]()
$130
This Super.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:41 pm -
Nonstop2h 59m
Fri 11/138:00 pm -
Nonstop3h 15m
Deal found 10/25![Allegiant Air logo]()
$141
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:56 pm -
Nonstop2h 59m
Fri 11/68:00 pm -
Nonstop3h 15m
Deal found 10/21![Allegiant Air logo]()
$155
This CheapOair deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:41 pm -
Nonstop2h 59m
Mon 11/237:59 pm -
Nonstop3h 12m
Deal found 10/21![Allegiant Air logo]()
$157
This Super.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:41 pm -
Nonstop2h 59m
Fri 11/207:59 pm -
Nonstop3h 12m
Deal found 10/23![Allegiant Air logo]()
$178
Best flights from Des Moines to Fort MyersDiscover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/226:20 am -
1 stop5h 36m
Fri 1/295:35 am -
1 stop5h 43m
Deal found 10/23![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:30 am -
2 stops11h 02m
Thu 11/127:06 am -
2 stops11h 22m
Deal found 10/23![United Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:58 pm -
1 stop5h 37m
Tue 12/85:20 am -
1 stop6h 29m
Deal found 10/22![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/45:15 pm -
1 stop6h 20m
Tue 3/164:30 pm -
1 stop6h 59m
Deal found 10/25![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:30 am -
2 stops9h 27m
Thu 12/102:29 pm -
1 stop8h 52m
Deal found 10/24![United Airlines logo]()
$509
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/234:00 pm -
1 stop5h 54m
Mon 4/265:35 am -
1 stop5h 43m
Deal found 10/23![Delta logo]()
$477
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/25:00 am -
2 stops9h 27m
Thu 1/79:02 am -
2 stops12h 36m
Deal found 10/25![United Airlines logo]()
$526
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:36 am -
1 stop4h 17m
Sat 11/1411:18 am -
1 stop5h 03m
Deal found 10/25![Delta logo]()
$557
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:59 pm -
1 stop5h 38m
Wed 11/112:43 pm -
1 stop7h 30m
Deal found 10/25![Delta logo]()
$557
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:36 am -
1 stop4h 17m
Fri 11/132:16 pm -
1 stop7h 27m
Deal found 10/25![Delta logo]()
$557
Last-minute flights from Des Moines to Fort MyersDiscover last-minute flight deals from Des Moines to Fort Myers. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Fort Myers. Data last updated October 26, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:04 pm -
Nonstop2h 59m
Fri 11/68:00 pm -
Nonstop3h 15m
Deal found 10/21![Allegiant Air logo]()
$130
This Super.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:04 pm -
Nonstop2h 59m
Mon 11/27:45 pm -
Nonstop3h 15m
Deal found 10/20![Allegiant Air logo]()
$175
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:56 pm -
Nonstop2h 59m
Fri 11/68:00 pm -
Nonstop3h 15m
Deal found 10/21![Allegiant Air logo]()
$155
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:41 pm -
Nonstop2h 59m
Fri 11/138:00 pm -
Nonstop3h 15m
Deal found 10/25![Allegiant Air logo]()
$145
This CheapOair deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:41 pm -
Nonstop2h 59m
Mon 11/237:59 pm -
Nonstop3h 12m
Deal found 10/21![Allegiant Air logo]()
$157
This Super.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:41 pm -
Nonstop2h 59m
Fri 11/207:59 pm -
Nonstop3h 12m
Deal found 10/23![Allegiant Air logo]()
$178
One-way flights from Des Moines to Fort MyersSearch for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This CheapOair deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:05 pm -
Nonstop2h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Allegiant Air logo]()
$38
This CheapOair deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:00 am -
Nonstop2h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Allegiant Air logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/42:50 pm -
Nonstop2h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Allegiant Air logo]()
$132
This Super.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:56 pm -
Nonstop2h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Allegiant Air logo]()
$142
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/511:22 am -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$178
This Super.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:11 pm -
Nonstop2h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Allegiant Air logo]()
$195
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop5h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Delta logo]()
$208
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/43:26 pm -
2 stops8h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![American Airlines logo]()
$223
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:25 am -
2 stops9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$224
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:06 am -
1 stop8h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:40 am -
3 stops31h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$241
Find flight deals from Des Moines to Fort Myers
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $86 (CheapOair) |
One-way from | $38 (CheapOair) |
Popular in | December |
Cheapest in | September |
Average price | $230 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Mon 12/7
3:05 pm-7:03 pm
Nonstop2h 58m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$38
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Mon 1/4
2:50 pm-6:48 pm
Nonstop2h 58m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$132
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Tue 1/5
9:00 am-7:40 pm
1 stop9h 40m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$178
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Mon 1/4
5:23 pm-12:35 am
1 stop6h 12m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$178
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 11/27
6:45 am-1:20 pm
1 stop5h 35m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$208
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 11/27
5:25 am-3:55 pm
2 stops9h 30m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$224
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Thu 11/19
6:06 am-3:22 pm
1 stop8h 16m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$232
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 1/8
9:00 am-7:40 pm
1 stop9h 40m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$243
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Tue 12/29
6:43 pm-12:53 am
1 stop5h 10m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$279
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 1/22
6:20 am-12:56 pm
1 stop5h 36m
Fort Myers SW Florida Intl
Fri 1/29
5:35 am-10:18 am
1 stop5h 43m
$375
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Fort Myers
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Fort Myers
Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
DSM-RSW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Fort Myers
How far ahead should I book a flight from Des Moines to Fort Myers?
The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 30 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Fort Myers?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $126). Flying from Des Moines to Fort Myers in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to RSW?
Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 26, 2026.
When flying from Des Moines to Fort Myers, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Fort Myers
Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated October 26, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.4
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Fort Myers?
Book flights to Fort Myers if you plan to visit one of these locationsNorth Fort Myers
Estero
Lehigh Acres
Sanibel
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Des Moines and Fort Myers flights
Browse other Des Moines and Fort Myers flight options. Last updated on October 26, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 26, 2026.
Popular flight searches
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Top 5 airlines flying from Des Moines to Fort Myers
Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$91 | Average$207 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$174 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$280 | Average$389 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$286 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$459 | FlexibilityNo cancel fee | On-time63% |