$57+ Cheap flights from South Carolina to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Jun 21 — Jun 281
1 adult, Economy
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Find cheap flights from South Carolina to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Florida Keys
Keep the following information in mind while searching for South Carolina to Florida Keys flight deals. Data was last updated June 16, 2025.
Round-trip from | $124 (Kiwi.com) |
|---|---|
One-way from | $57 (FlightHub) |
Popular in | March |
Cheapest in | October |
Average price | $302 |
Find flight deals from South Carolina to Florida Keys
Cheapest flights from South Carolina to Florida KeysExplore the most affordable flight options available from South Carolina to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.
Explore the most affordable flight options available from South Carolina to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/289:32 pmCLT - MIA
Nonstop2h 10mSpirit Airlines
Sun 6/296:00 amMIA - CLT
Nonstop2h 09mSpirit Airlines
Deal found 6/15![Spirit Airlines logo]()
$124
This Cheapflightsfares deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1210:03 pmCLT - MIA
Nonstop2h 12mFrontier
Fri 10/176:07 amMIA - CLT
Nonstop2h 11mFrontier
Deal found 6/14![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/299:07 amCLT - MIA
Nonstop2h 14mMultiple Airlines
Fri 7/47:00 amMIA - CLT
1 stop7h 28mMultiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$131
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/91:00 pmSAV - MIA
1 stop8h 15mSouthwest
Wed 9/1711:40 amMIA - SAV
1 stop5h 45mSouthwest
Deal found 6/15![Southwest logo]()
$156
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/65:35 amCAE - MIA
1 stop3h 53mDelta
Wed 8/137:30 amMIA - CAE
1 stop4h 49mDelta
Deal found 6/14![Delta logo]()
$179
This Cheapflightsfares deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1912:18 pmMYR - MIA
1 stop6h 35mSpirit Airlines
Sun 9/287:00 amMIA - MYR
1 stop6h 47mSpirit Airlines
Deal found 6/14![Spirit Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/309:31 pmCHS - EYW
1 stop11h 51mBreeze Airways
Fri 7/41:47 pmEYW - CHS
1 stop19h 27mBreeze Airways
Deal found 6/15![Breeze Airways logo]()
$189
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1310:26 amCHS - MIA
Nonstop1h 48mAmerican Airlines
Tue 7/158:05 amMIA - CHS
Nonstop1h 41mAmerican Airlines
Deal found 6/14![American Airlines logo]()
$197
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/225:14 pmCHS - MIA
1 stop4h 04mDelta
Fri 8/157:30 pmMIA - CHS
1 stop4h 21mDelta
Deal found 6/15![Delta logo]()
$198
This FlightHub deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/87:03 amCHS - MIA
1 stop12h 57mSpirit Airlines
Wed 7/95:16 pmMIA - CHS
1 stop20h 11mSpirit Airlines
Deal found 6/14![Spirit Airlines logo]()
$212
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/86:10 amCHS - MIA
1 stop4h 40mSouthwest
Sat 9/206:55 amMIA - CHS
2 stops9h 45mSouthwest
Deal found 6/13![Southwest logo]()
$215
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:45 pmMYR - MIA
1 stop6h 07mDelta
Tue 11/1812:05 pmMIA - MYR
1 stop5h 50mDelta
Deal found 6/16![Delta logo]()
$217
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.
Fly from
South Carolina
Fly to
Florida Keys
Route
Depart
Return
Price
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sat 6/28
9:32 pm-11:42 pm
Nonstop2h 10m
Miami
Sun 6/29
6:00 am-8:09 am
Nonstop2h 09m
$124
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sun 10/12
10:03 pm-12:15 am
Nonstop2h 12m
Miami
Fri 10/17
6:07 am-8:18 am
Nonstop2h 11m
$125
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sun 6/29
9:07 am-11:21 am
Nonstop2h 14m
Miami
Fri 7/4
7:00 am-2:28 pm
1 stop7h 28m
$131
SavannahMiami
SAV - MIA
SAVMIA
Savannah/Hilton Head
Tue 9/9
1:00 pm-9:15 pm
1 stop8h 15m
Miami
Wed 9/17
11:40 am-5:25 pm
1 stop5h 45m
$156
ColumbiaMiami
CAE - MIA
CAEMIA
Columbia Metropolitan
Wed 8/6
5:35 am-9:28 am
1 stop3h 53m
Miami
Wed 8/13
7:30 am-12:19 pm
1 stop4h 49m
$179
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Fri 9/19
12:18 pm-6:53 pm
1 stop6h 35m
Miami
Sun 9/28
7:00 am-1:47 pm
1 stop6h 47m
$181
CharlestonKey West
CHS - EYW
CHSEYW
Charleston
Mon 6/30
9:31 pm-9:22 am
1 stop11h 51m
Key West
Fri 7/4
1:47 pm-9:14 am
1 stop19h 27m
$189
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Sun 7/13
10:26 am-12:14 pm
Nonstop1h 48m
Miami
Tue 7/15
8:05 am-9:46 am
Nonstop1h 41m
$197
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Tue 7/22
5:14 pm-9:18 pm
1 stop4h 04m
Miami
Fri 8/15
7:30 pm-11:51 pm
1 stop4h 21m
$198
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Tue 7/8
7:03 am-8:00 pm
1 stop12h 57m
Miami
Wed 7/9
5:16 pm-1:27 pm
1 stop20h 11m
$212
Showing 1-10 of 60 results
Best time to book a flight from South Carolina to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Florida Keys
What is the cheapest month to book a flight from South Carolina to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from South Carolina to Florida Keys (average of $328). Flying from South Carolina to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to EOA?
Find hourly flight availability from South Carolina to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Florida Keys as you normally would.
Rainfall in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.
Temperature in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated June 16, 2025.
Peruse reviews from past customers who have flown with Breeze Airways, Alaska Airlines and Southwest from South Carolina to Florida Keys to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Crew
8.8
Overall
8.1
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Crew
8.8
Overall
8.1
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Crew
8.8
Overall
8.1
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Crew
8.8
Overall
8.1
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Crew
8.8
Overall
8.1
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Crew
8.8
Overall
8.1
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from South Carolina to Florida Keys
Discover the top 2 airlines that operate flights from South Carolina to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$416 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$483 | FlexibilityNo cancel fee | On-time71% |