How long is the flight from San Francisco to Florence, South Carolina?

Airlines like American Airlines fly from San Francisco to Florence, South Carolina in about 6h 42m. The time it takes to get you to your destination can typically vary by up to . The distance between San Francisco and Florence, South Carolina is about 2377 mi.

What is the cheapest airline to fly from San Francisco to Florence, South Carolina round-trip?

Flying on American Airlines is currently your cheapest option to Florence, South Carolina, with prices starting at $400.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from SFO to FLO?

When flying from San Francisco to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on San Francisco-Florence, South Carolina flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Florence, South Carolina flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Florence, South Carolina flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on San Francisco-Florence, South Carolina flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from San Francisco to Florence that include hotel bookings?

Yes. In addition to deals on San Francisco to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Francisco to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Florence.

Can I find deals for business class flights from San Francisco to Florence?

Yes. Cheapflights offers flight deals from San Francisco to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$577+ Flights from San Francisco to Florence, SC

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Best flights from San Francisco to Florence
Discover carefully curated flight deals from San Francisco to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Wed 3/251:56 pmSFO - FLO

1 stop6h 42mAmerican Airlines

Sat 3/2811:09 amFLO - SFO

1 stop9h 07mAmerican Airlines

Deal found 10/27

$577

Cheap flight deals from San Francisco to Florence

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$577 (American Airlines)

Provider with most accurate pricing for San Francisco-Florence flight deals.

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Provider most trusted by Cheapflights users for San Francisco-Florence flights.

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From San Francisco to Florence

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Use the filters below to find and compare flights from San Francisco to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Wed 3/25

1:56 pm-11:38 pm

1 stop6h 42m

Florence

Sat 3/28

11:09 am-5:16 pm

1 stop9h 07m

$577

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Compare providers for flights from San Francisco to Florence

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Florence in October.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on San Francisco-Florence, South Carolina flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Florence, South Carolina flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Florence, South Carolina flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on San Francisco-Florence, South Carolina flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Florence

What is the cheapest month to book a flight from San Francisco to Florence, South Carolina?

Currently, May is the cheapest month in which you can book a flight from San Francisco to Florence, South Carolina (average of $148). Flying from San Francisco to Florence, South Carolina in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get a feel of what it's like to fly with American Airlines from San Francisco to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,030 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

American Airlines

7.2

Good

11,030 reviews

American Airlines

7.2

Good

11,030 reviews

Reviews

1 / 20

2.0

Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

How long is the flight from San Francisco to Florence, South Carolina?
Airlines like American Airlines fly from San Francisco to Florence, South Carolina in about 6h 42m. The time it takes to get you to your destination can typically vary by up to . The distance between San Francisco and Florence, South Carolina is about 2377 mi.
What is the cheapest airline to fly from San Francisco to Florence, South Carolina round-trip?
Flying on American Airlines is currently your cheapest option to Florence, South Carolina, with prices starting at $400.
Can I find deals for flights from San Francisco to Florence that include hotel bookings?
Yes. In addition to deals on San Francisco to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Florence.
Can I find deals for business class flights from San Francisco to Florence?
Yes. Cheapflights offers flight deals from San Francisco to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Florence, South Carolina?
Currently, May is the cheapest month in which you can book a flight from San Francisco to Florence, South Carolina (average of $148). Flying from San Francisco to Florence, South Carolina in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from San Francisco to Florence

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$400	Average$512	FlexibilityNo cancel fee	On-time71%

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$577+ Cheap flights from San Francisco to Florence, SC (SFO - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from San Francisco to Florence

Best flights from San Francisco to FlorenceDiscover carefully curated flight deals from San Francisco to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Discover carefully curated flight deals from San Francisco to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Cheap flight deals from San Francisco to Florence

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Florence that are best for you.

Compare providers for flights from San Francisco to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Florence in October.

Best time to book a flight from San Francisco to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Florence

What is the cheapest month to book a flight from San Francisco to Florence, South Carolina?

Reviews of airlines servicing Florence

Get a feel of what it's like to fly with American Airlines from San Francisco to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from San Francisco to Florence, South Carolina?

What is the cheapest airline to fly from San Francisco to Florence, South Carolina round-trip?

Can I find deals for flights from San Francisco to Florence that include hotel bookings?

How can I find direct flights from San Francisco to Florence?

Can I find deals for business class flights from San Francisco to Florence?

What is the cheapest month to book a flight from San Francisco to Florence, South Carolina?

Traveling to a place near Florence?

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Alternative routes for San Francisco to Florence

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Top airline flying from San Francisco to Florence

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Best flights from San Francisco to Florence
Discover carefully curated flight deals from San Francisco to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.