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$299+ Cheap flights from Rochester to Florence, SC (ROC - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — FLO
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Rochester to Florence

Cheapest flights from Rochester to Florence
Explore the most affordable flight options available from Rochester to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
ROC
-
FLO
2 stops15h 47m
American Airlines
Sun 5/105:20 am
FLO
-
ROC
2 stops11h 52m
American Airlines
Deal found 4/21$548
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:05 am
ROC
-
FLO
2 stops8h 05m
American Airlines
Sun 6/142:35 pm
FLO
-
ROC
2 stops9h 13m
American Airlines
Deal found 4/22$551
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:20 am
ROC
-
FLO
2 stops8h 50m
American Airlines
Sat 6/205:05 am
FLO
-
ROC
1 stop6h 28m
American Airlines
Deal found 4/19$568
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:19 pm
ROC
-
FLO
2 stops8h 39m
American Airlines
Sat 8/225:09 am
FLO
-
ROC
1 stop5h 46m
American Airlines
Deal found 4/19$586
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:05 am
ROC
-
FLO
2 stops8h 05m
American Airlines
Sat 6/205:05 am
FLO
-
ROC
1 stop6h 28m
American Airlines
Deal found 4/19$601
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:12 pm
ROC
-
FLO
2 stops6h 35m
American Airlines
Sat 4/254:16 pm
FLO
-
ROC
1 stop6h 02m
American Airlines
Deal found 4/21$619

Find flight deals from Rochester to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$548
(American Airlines)

One-way from

$299
(American Airlines)
Provider with most accurate pricing for Greater Rochester Intl-Florence flight deals.
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Provider most trusted by Cheapflights users for Greater Rochester Intl-Florence flights.
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From Greater Rochester Intl to Florence
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One-way flight from Greater Rochester Intl to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Rochester to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Tue 6/16

5:20 am-2:10 pm

2 stops8h 50m

Florence

Sat 6/20

5:05 am-11:33 am

1 stop6h 28m

$568

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Wed 6/17

5:20 am-2:10 pm

2 stops8h 50m

Florence

Sat 6/20

5:05 am-11:33 am

1 stop6h 28m

$568

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Sat 8/15

3:19 pm-11:58 pm

2 stops8h 39m

Florence

Sat 8/22

5:09 am-10:55 am

1 stop5h 46m

$586

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Thu 6/18

6:05 am-2:10 pm

2 stops8h 05m

Florence

Sat 6/20

5:05 am-2:52 pm

2 stops9h 47m

$606
Quickest round-trip

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Fri 5/8

7:30 am-3:50 pm

2 stops8h 20m

Florence

Sat 5/9

4:16 pm-10:18 pm

1 stop6h 02m

$619
Cheapest one-way
Quickest one-way

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Tue 4/28

6:20 pm-10:42 pm

1 stop4h 22m

$299

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Wed 5/20

5:15 am-3:50 pm

2 stops10h 35m

$418

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Sorted by cheapest first

Compare providers for flights from Rochester to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Rochester to Florence in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Rochester-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rochester-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rochester-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rochester-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rochester-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rochester to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester to Florence, South Carolina?

    A quick flight from Rochester to Florence, South Carolina can take about 8h 50m. American Airlines provides one of the quickest options available for as low as $568. Rochester and Florence, South Carolina are separated by a distance of 627 mi.

  • Can I find deals for flights from Rochester to Florence that include hotel bookings?

    Yes. In addition to deals on Rochester to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Florence.

  • Can I find deals for business class flights from Rochester to Florence?

    Yes. Cheapflights offers flight deals from Rochester to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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