HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$473+ Cheap flights from Rochester to Florence, SC (ROC - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
ROC — FLO
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Rochester to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Rochester to Florence

Cheapest flights from Rochester to Florence
Explore the most affordable flight options available from Rochester to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:20 pm
ROC
-
FLO
1 stop6h 42m
American Airlines
Sat 8/225:14 am
FLO
-
ROC
1 stop6h 01m
American Airlines
Deal found 3/20$473
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:28 am
ROC
-
FLO
1 stop4h 22m
American Airlines
Sat 8/295:14 am
FLO
-
ROC
1 stop6h 01m
American Airlines
Deal found 3/22$587
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:54 pm
ROC
-
FLO
2 stops6h 08m
American Airlines
Fri 8/282:34 pm
FLO
-
ROC
2 stops9h 10m
American Airlines
Deal found 3/21$597
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:20 pm
ROC
-
FLO
1 stop6h 42m
American Airlines
Sat 8/2911:15 am
FLO
-
ROC
1 stop5h 25m
American Airlines
Deal found 3/21$607
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:28 am
ROC
-
FLO
1 stop4h 22m
American Airlines
Sun 8/3011:15 am
FLO
-
ROC
1 stop5h 25m
American Airlines
Deal found 3/21$611
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:28 am
ROC
-
FLO
1 stop4h 22m
American Airlines
Fri 8/2811:15 am
FLO
-
ROC
1 stop5h 25m
American Airlines
Deal found 3/22$621

Find flight deals from Rochester to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (ROC) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$473
(American Airlines)
Provider with most accurate pricing for Greater Rochester Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greater Rochester Intl-Florence flights.
Search Deals
From Greater Rochester Intl to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Rochester to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Sat 8/15

6:28 am-10:50 am

1 stop4h 22m

Florence

Sat 8/22

5:14 am-11:15 am

1 stop6h 01m

$473
Quickest round-trip

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Sat 8/22

6:28 am-10:50 am

1 stop4h 22m

Florence

Sat 8/29

11:15 am-4:40 pm

1 stop5h 25m

$473

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Sat 8/22

6:28 am-10:50 am

1 stop4h 22m

Florence

Sun 8/30

11:15 am-4:40 pm

1 stop5h 25m

$611

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Sun 8/23

8:00 am-2:09 pm

2 stops6h 09m

Florence

Sat 8/29

2:34 pm-11:44 pm

2 stops9h 10m

$617

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Fri 8/21

6:28 am-10:50 am

1 stop4h 22m

Florence

Sun 8/30

5:14 am-11:23 am

2 stops6h 09m

$646

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Sorted by cheapest first

Compare providers for flights from Rochester to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Rochester to Florence in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Rochester-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rochester-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rochester-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rochester-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rochester-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rochester to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Florence

What is the cheapest month to book a flight from Rochester to Florence, South Carolina?

Currently, April is the cheapest month in which you can book a flight from Rochester to Florence, South Carolina (average of $48). Flying from Rochester to Florence, South Carolina in August is currently the most expensive (average of $115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester to Florence, South Carolina?

    A quick flight from Rochester to Florence, South Carolina can take about 4h 22m. American Airlines provides one of the quickest options available for as low as $473. Rochester and Florence, South Carolina are separated by a distance of 627 mi.

  • Can I find deals for flights from Rochester to Florence that include hotel bookings?

    Yes. In addition to deals on Rochester to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Florence.

  • Can I find deals for business class flights from Rochester to Florence?

    Yes. Cheapflights offers flight deals from Rochester to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester to Florence, South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Rochester to Florence, South Carolina (average of $48). Flying from Rochester to Florence, South Carolina in August is currently the most expensive (average of $115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Rochester to Florence

See prices for flight routes from nearby airports that may be better suited for you.
LaGuardia to Charleston flights
John F Kennedy Intl to Charlotte flights
John F Kennedy Intl to Charleston flights
LaGuardia to Charlotte flights
Newark to Charleston flights
Newark to Charlotte flights
Newark to Savannah flights
John F Kennedy Intl to Savannah flights
LaGuardia to Savannah flights
John F Kennedy Intl to Myrtle Beach flights
Newark to Myrtle Beach flights
White Plains to Charleston flights
LaGuardia to Myrtle Beach flights
Newark to Greenville flights
LaGuardia to Greenville flights
Newark to Hilton Head Island flights
LaGuardia to Hilton Head Island flights
John F Kennedy Intl to Greenville flights
LaGuardia to Columbia flights
Newark to Columbia flights
John F Kennedy Intl to Columbia flights
Stewart to Charleston flights
Stewart to Myrtle Beach flights
Rochester to Charlotte flights
Syracuse to Charlotte flights
Buffalo to Charlotte flights
White Plains to Myrtle Beach flights
Syracuse to Savannah flights
White Plains to Savannah flights
Newark to Augusta flights
John F Kennedy Intl to Augusta flights
Rochester to Charleston flights
Islip to Charleston flights
Buffalo to Charleston flights
Albany to Charlotte flights
Buffalo to Myrtle Beach flights
Islip to Myrtle Beach flights
Rochester to Savannah flights
Rochester to Myrtle Beach flights
Albany to Charleston flights
LaGuardia to Augusta flights
White Plains to Charlotte flights
Syracuse to Myrtle Beach flights
Albany to Savannah flights
Albany to Myrtle Beach flights
Stewart to Charlotte flights
Buffalo to Savannah flights
Albany to Greenville flights
Stewart to Greenville flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.