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Florence

$289+ Cheap flights from Pennsylvania to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — FLO
May 18 — May 251
Mon 5/18
Mon 5/25
1 adult, Economy
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Cheap flight deals from Pennsylvania to Florence

Cheapest flights from Pennsylvania to Florence
Explore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.

This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:16 am
LGA
-
FLO
1 stop5h 34m
American Airlines
Sat 5/165:20 am
FLO
-
LGA
1 stop3h 59m
American Airlines
Deal found 4/15$289
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:00 am
JFK
-
FLO
1 stop4h 50m
American Airlines
Sat 5/164:16 pm
FLO
-
JFK
1 stop6h 00m
American Airlines
Deal found 4/14$289
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:30 am
JFK
-
FLO
2 stops7h 40m
American Airlines
Sat 8/295:09 am
FLO
-
JFK
1 stop6h 19m
American Airlines
Deal found 4/14$294
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:32 am
IAD
-
FLO
1 stop5h 00m
American Airlines
Sat 5/25:20 am
FLO
-
IAD
1 stop3h 29m
American Airlines
Deal found 4/13$299
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:16 am
LGA
-
FLO
1 stop5h 34m
American Airlines
Mon 5/44:16 pm
FLO
-
LGA
1 stop3h 43m
American Airlines
Deal found 4/14$329
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:30 pm
JFK
-
FLO
1 stop7h 17m
American Airlines
Mon 5/44:16 pm
FLO
-
JFK
1 stop4h 07m
American Airlines
Deal found 4/15$329
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:59 am
JFK
-
FLO
1 stop6h 11m
American Airlines
Sat 6/202:35 pm
FLO
-
JFK
1 stop5h 40m
American Airlines
Deal found 4/13$344
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:30 am
EWR
-
FLO
1 stop6h 40m
American Airlines
Sat 6/202:35 pm
FLO
-
EWR
1 stop4h 04m
American Airlines
Deal found 4/13$344
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:30 am
EWR
-
FLO
1 stop6h 40m
American Airlines
Sun 5/315:05 am
FLO
-
EWR
1 stop4h 54m
American Airlines
Deal found 4/13$364
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:00 am
JFK
-
FLO
1 stop4h 50m
American Airlines
Sat 5/235:05 am
FLO
-
JFK
1 stop6h 24m
American Airlines
Deal found 4/17$375
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:30 am
EWR
-
FLO
1 stop6h 40m
American Airlines
Sat 8/292:37 pm
FLO
-
EWR
1 stop5h 53m
American Airlines
Deal found 4/14$375
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:58 am
LGA
-
FLO
1 stop4h 12m
American Airlines
Sat 7/252:35 pm
FLO
-
LGA
1 stop3h 54m
American Airlines
Deal found 4/17$379

Find flight deals from Pennsylvania to Florence

Keep the following information in mind while searching for Pennsylvania to Florence flight deals. Data was last updated April 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(American Airlines)
Provider with most accurate pricing for Philadelphia-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Philadelphia-Florence flights.
Search Deals
From Pennsylvania to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pennsylvania to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Pennsylvania to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Tue 5/12

5:23 pm-10:42 pm

1 stop5h 19m

Florence

Sat 5/16

4:16 pm-7:59 pm

1 stop3h 43m

$289

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 5/16

10:04 am-3:50 pm

1 stop5h 46m

Florence

Sat 5/23

2:35 pm-7:45 pm

1 stop5h 10m

$289

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Wed 6/10

3:30 pm-10:00 pm

1 stop6h 30m

Florence

Sat 8/29

5:09 am-11:28 am

1 stop6h 19m

$289

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Sat 5/9

11:00 am-3:50 pm

1 stop4h 50m

Florence

Sat 5/16

4:16 pm-10:16 pm

1 stop6h 00m

$289

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 5/1

3:04 pm-9:47 pm

1 stop6h 43m

Florence

Tue 5/5

6:15 am-11:05 am

1 stop4h 50m

$329

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Thu 4/30

2:30 pm-9:47 pm

1 stop7h 17m

Florence

Mon 5/4

4:16 pm-8:23 pm

1 stop4h 07m

$329

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Fri 5/1

2:30 pm-9:47 pm

1 stop7h 17m

Florence

Tue 5/5

4:02 pm-8:24 pm

1 stop4h 22m

$329

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Fri 5/29

7:30 am-2:10 pm

1 stop6h 40m

Florence

Sun 5/31

5:05 am-9:59 am

1 stop4h 54m

$364

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Sat 5/16

11:00 am-3:50 pm

1 stop4h 50m

Florence

Sat 5/23

5:05 am-11:29 am

1 stop6h 24m

$375

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 7/22

9:58 am-2:10 pm

1 stop4h 12m

Florence

Sat 7/25

2:35 pm-6:29 pm

1 stop3h 54m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/14

Showing 1-10 of 54 resultsSorted by cheapest first
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Best time to book a flight from Pennsylvania to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Pennsylvania with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Florence
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Pennsylvania to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Pennsylvania?

    Most people fly into Florence (FLO) if they book a flight to Florence from Pennsylvania. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Pennsylvania to Florence, South Carolina?

    American Airlines can get you from Pennsylvania to Florence, South Carolina in just under 5h 19m. Your travel time can differ by up to . The distance between Pennsylvania and Florence, South Carolina is about 556 mi.

  • What are the most popular routes from Pennsylvania to Florence, South Carolina?

    The most popular flight routes from Pennsylvania to Florence, South Carolina are New York John F Kennedy Intl - Florence, Newark - Florence and New York LaGuardia - Florence.

  • Can I find deals for flights from Pennsylvania to Florence that include hotel bookings?

    Yes. In addition to deals on Pennsylvania to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pennsylvania to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Florence.

  • Can I find deals for business class flights from Pennsylvania to Florence?

    Yes. Cheapflights offers flight deals from Pennsylvania to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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