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Florence

$265+ Cheap flights from Pennsylvania to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
PHL ā€” FLO
Aug 21 ā€” Aug 281
Fri 8/21
Fri 8/28
1 adult, Economy
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Cheap flight deals from Pennsylvania to Florence

Cheapest flights from Pennsylvania to Florence
Explore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.

This American Airlines deal was found by Cheapflights users on 7/18. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 8/195:00 pm
LGA
-
FLO
1 stop5h 59m
American Airlines
Wed 8/263:22 pm
FLO
-
LGA
1 stop4h 37m
American Airlines
Deal found 7/18$353
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 8/195:00 pm
JFK
-
FLO
1 stop5h 59m
American Airlines
Wed 8/266:22 am
FLO
-
JFK
1 stop4h 08m
American Airlines
Deal found 7/20$353
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 9/95:29 pm
EWR
-
FLO
1 stop5h 29m
American Airlines
Wed 9/161:43 pm
FLO
-
EWR
1 stop7h 04m
American Airlines
Deal found 7/20$353
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 8/125:00 pm
LGA
-
FLO
1 stop5h 59m
American Airlines
Wed 8/196:22 am
FLO
-
LGA
1 stop5h 04m
American Airlines
Deal found 7/18$407
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 8/128:00 am
JFK
-
FLO
1 stop6h 56m
American Airlines
Wed 8/193:22 pm
FLO
-
JFK
1 stop4h 38m
American Airlines
Deal found 7/18$407
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 12/27:15 pm
LGA
-
FLO
1 stop4h 48m
American Airlines
Fri 12/116:31 pm
FLO
-
LGA
1 stop4h 56m
American Airlines
Deal found 7/18$410
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 12/211:00 am
JFK
-
FLO
1 stop7h 05m
American Airlines
Fri 12/116:31 pm
FLO
-
JFK
1 stop3h 52m
American Airlines
Deal found 7/18$410
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Sun 11/15:27 pm
EWR
-
FLO
1 stop6h 36m
American Airlines
Sat 11/75:15 am
FLO
-
EWR
1 stop4h 15m
American Airlines
Deal found 7/17$410
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Tue 8/185:00 pm
LGA
-
FLO
1 stop5h 59m
American Airlines
Tue 8/253:22 pm
FLO
-
LGA
1 stop4h 38m
American Airlines
Deal found 7/18$433
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Tue 8/185:00 pm
JFK
-
FLO
1 stop5h 59m
American Airlines
Sat 8/293:22 pm
FLO
-
JFK
1 stop4h 38m
American Airlines
Deal found 7/18$433
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 11/189:30 am
EWR
-
FLO
1 stop5h 39m
American Airlines
Wed 11/252:35 pm
FLO
-
EWR
1 stop5h 54m
American Airlines
Deal found 7/19$433
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the ā€œPick Datesā€ button in this card will allow you to select your dates and further customize your flight criteria. From there, click ā€œFind dealsā€, make sure American Airlines is selected, and click ā€œCompare selectedā€ under the list of providers to see comparable flight deals.
Wed 8/125:00 pm
LGA
-
FLO
1 stop5h 59m
American Airlines
Sat 8/153:22 pm
FLO
-
LGA
1 stop4h 37m
American Airlines
Deal found 7/19$461

Find flight deals from Pennsylvania to Florence

Keep the following information in mind while searching for Pennsylvania to Florence flight deals. Data was last updated July 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$353
(American Airlines)

One-way from

$265
(American Airlines)
Provider with most accurate pricing for Philadelphia-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Philadelphia-Florence flights.
Search Deals
From Pennsylvania to Florence
Search Deals
One-way flight from Pennsylvania to Florence
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Cheapflights Fare Finder

Ā 
Customize your flight search to find flights from Pennsylvania to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Pennsylvania to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Sun 11/1

5:27 pm-12:03 am

1 stop6h 36m

Florence

Sat 11/7

5:15 am-9:30 am

1 stop4h 15m

$410

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Wed 11/18

5:00 pm-10:59 pm

1 stop5h 59m

Florence

Wed 11/25

2:35 pm-8:29 pm

1 stop5h 54m

$433

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 8/12

5:00 pm-10:59 pm

1 stop5h 59m

Florence

Sat 8/15

3:22 pm-7:59 pm

1 stop4h 37m

$461

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Wed 8/12

5:00 pm-10:59 pm

1 stop5h 59m

Florence

Sat 8/15

3:22 pm-8:00 pm

1 stop4h 38m

$461

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 11/17

8:30 am-3:16 pm

1 stop6h 46m

Florence

Tue 11/24

5:09 am-9:20 am

1 stop4h 11m

$463

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Sat 11/21

7:46 pm-11:54 pm

1 stop4h 08m

Florence

Wed 11/25

2:35 pm-8:29 pm

1 stop5h 54m

$487

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 9/5

2:29 pm-9:20 pm

1 stop6h 51m

Florence

Mon 9/7

3:22 pm-7:59 pm

1 stop4h 37m

$490

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Fri 9/4

5:00 pm-10:59 pm

1 stop5h 59m

Florence

Tue 9/8

6:22 am-11:30 am

1 stop5h 08m

$490

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Wed 9/23

5:29 pm-10:58 pm

1 stop5h 29m

Florence

Mon 9/28

6:24 am-12:40 pm

1 stop6h 16m

$490

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 11/18

1:50 pm-6:07 pm

1 stop4h 17m

Florence

Mon 11/30

6:33 pm-12:02 am

1 stop5h 29m

$511

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/20

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Pennsylvania to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Pennsylvania with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Florence

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Pennsylvania to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Pennsylvania?

    Most people fly into Florence (FLO) if they book a flight to Florence from Pennsylvania. Florence is conveniently located just 2.3 mi from Florenceā€™s city center.

  • How long is the flight from Pennsylvania to Florence, South Carolina?

    American Airlines can get you from Pennsylvania to Florence, South Carolina in just under 6h 36m. Your travel time can differ by up to . The distance between Pennsylvania and Florence, South Carolina is about 543 mi.

  • What are the most popular routes from Pennsylvania to Florence, South Carolina?

    The most popular flight routes from Pennsylvania to Florence, South Carolina are New York LaGuardia - Florence, Newark - Florence and New York John F Kennedy Intl - Florence.

  • Can I find deals for flights from Pennsylvania to Florence that include hotel bookings?

    Yes. In addition to deals on Pennsylvania to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pennsylvania to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Florence.

  • Can I find deals for business class flights from Pennsylvania to Florence?

    Yes. Cheapflights offers flight deals from Pennsylvania to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
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