$442+ Cheap flights from Orlando (ORL) to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
ORL — FLO
Oct 29 — Nov 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Orlando to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Orlando to Florence
Cheapest
Best
Last-minute
One-way
Cheapest flights from Orlando to FlorenceExplore the most affordable flight options available from Orlando to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from Orlando to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop6h 09m
Sat 11/73:37 pm -
1 stop4h 35m
Deal found 9/26![American Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
1 stop6h 09m
Sat 11/73:37 pm -
1 stop4h 35m
Deal found 9/27![American Airlines logo]()
$511
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:03 am -
1 stop5h 06m
Wed 10/145:09 am -
1 stop6h 35m
Deal found 9/28![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:03 am -
1 stop5h 06m
Mon 11/26:24 am -
1 stop3h 46m
Deal found 9/27![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:00 am -
1 stop6h 18m
Sat 10/102:34 pm -
1 stop5h 25m
Deal found 9/28![American Airlines logo]()
$582
Best flights from Orlando to FlorenceDiscover carefully curated flight deals from Orlando to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from Orlando to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:15 am -
2 stops12h 19m
Sat 11/73:37 pm -
1 stop4h 35m
Deal found 9/26![American Airlines logo]()
$533
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:03 am -
1 stop5h 06m
Wed 10/145:09 am -
1 stop6h 35m
Deal found 9/28![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:03 am -
1 stop5h 06m
Mon 11/26:24 am -
1 stop3h 46m
Deal found 9/27![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:21 pm -
1 stop5h 51m
Sat 10/172:34 pm -
2 stops8h 18m
Deal found 9/28![American Airlines logo]()
$627
Last-minute flights from Orlando to FlorenceDiscover last-minute flight deals from Orlando to Florence. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from Orlando to Florence. Data last updated September 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:00 am -
1 stop6h 18m
Sat 10/102:34 pm -
1 stop5h 25m
Deal found 9/28![American Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:03 am -
1 stop5h 06m
Wed 10/145:09 am -
1 stop6h 35m
Deal found 9/25![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop6h 09m
Sat 11/73:37 pm -
1 stop4h 35m
Deal found 9/26![American Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
1 stop6h 09m
Sat 11/73:37 pm -
1 stop4h 35m
Deal found 9/27![American Airlines logo]()
$511
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:03 am -
1 stop5h 06m
Mon 11/26:24 am -
1 stop3h 46m
Deal found 9/27![American Airlines logo]()
$545
One-way flights from Orlando to FlorenceSearch for one-way flight options from Orlando to Florence. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from Orlando to Florence. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
1 stop6h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![American Airlines logo]()
$442
Find flight deals from Orlando to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Orlando (ORL) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $477 (American Airlines) |
One-way from | $442 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Orlando to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from Orlando to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Thu 10/29
8:00 am-2:09 pm
1 stop6h 09m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$442
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Wed 10/28
7:15 am-7:34 pm
2 stops12h 19m
Florence
Sat 11/7
3:37 pm-8:12 pm
1 stop4h 35m
$533
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Wed 10/7
9:03 am-2:09 pm
1 stop5h 06m
Florence
Wed 10/14
5:09 am-11:44 am
1 stop6h 35m
$537
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Fri 10/30
9:03 am-2:09 pm
1 stop5h 06m
Florence
Mon 11/2
6:24 am-10:10 am
1 stop3h 46m
$545
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Tue 10/13
5:21 pm-11:12 pm
1 stop5h 51m
Florence
Sat 10/17
2:34 pm-10:52 pm
2 stops8h 18m
$627
Sorted by cheapest first
Compare providers for flights from Orlando to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Orlando to Florence in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Orlando-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Orlando-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Orlando-Florence, South Carolina flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Orlando-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Orlando-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Orlando to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Orlando with our price prediction graph.
ORL-FLO
MCO-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Orlando to Florence
ORL-FLO
MCO-FLO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 29, 2026.
Get a feel of what it's like to fly with American Airlines from Orlando to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Food
6.4
Crew
7.9
Overall
7.0
Boarding
7.4
Entertainment
6.8
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Comfort
7.2
Food
6.4
Crew
7.9
Overall
7.0
Boarding
7.4
Entertainment
6.8
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Related info for your journey
Find useful and relevant information for your journey from Orlando to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsSumter
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Florence flight routes
Other flight options
Other flights from Orlando
Popular flights
Alternative routes for Orlando to Florence
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Orlando to Florence by cabin class
Find flights from Orlando to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Florence
Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 29, 2026.
Orlando and Florence flights
Browse other Orlando and Florence flight options. Last updated on September 29, 2026.
Other flights from Orlando
Browse through other flights departing from Orlando. Flights are based on user searches made on Cheapflights and were last updated on September 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Orlando to Florence
Discover the top airline that operate flights from Orlando to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$430 | Average$550 | FlexibilityNo cancel fee | On-time71% |