
Keep the following information in mind while searching for Orlando to South Carolina flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $81 (Cheapflightsfares) |
One-way from | $38 (Kiwi.com) |
Popular in | February |
Cheapest in | June |
Good round-trip deal | $61 or less |
Good one-way deal | $79 or less |
Fly from
Fly to
Route
Depart
Return
OrlandoGreenville
SFB Orlando Sanford Intl - GSP Greenville
SFBGSP
Orlando Sanford Intl
Thu 2/4
1:14 pm-2:41 pm
Nonstop1h 27m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoGreenville
SFB Orlando Sanford Intl - GSP Greenville
SFBGSP
Orlando Sanford Intl
Thu 12/17
1:12 pm-2:38 pm
Nonstop1h 26m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoCharleston
MCO Orlando - CHS Charleston
MCOCHS
Orlando
Thu 12/31
7:10 am-8:38 am
Nonstop1h 28m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoCharleston
MCO Orlando - CHS Charleston
MCOCHS
Orlando
Wed 11/11
7:10 am-8:38 am
Nonstop1h 28m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoGreenville
MCO Orlando - GSP Greenville
MCOGSP
Orlando
Thu 11/19
6:19 pm-7:59 pm
Nonstop1h 40m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoGreenville
SFB Orlando Sanford Intl - GSP Greenville
SFBGSP
Orlando Sanford Intl
Sun 1/24
1:14 pm-2:41 pm
Nonstop1h 27m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoGreenville
SFB Orlando Sanford Intl - GSP Greenville
SFBGSP
Orlando Sanford Intl
Sun 12/6
1:31 pm-2:59 pm
Nonstop1h 28m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoGreenville
SFB Orlando Sanford Intl - GSP Greenville
SFBGSP
Orlando Sanford Intl
Thu 12/31
1:12 pm-2:38 pm
Nonstop1h 26m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoCharleston
MCO Orlando - CHS Charleston
MCOCHS
Orlando
Sat 12/26
7:10 am-8:38 am
Nonstop1h 28m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
OrlandoGreenville
SFB Orlando Sanford Intl - GSP Greenville
SFBGSP
Orlando Sanford Intl
Thu 11/19
1:26 pm-2:52 pm
Nonstop1h 26m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Everything you need to know about your flight from Orlando to South Carolina
Food
Crew
Boarding
Overall
Entertainment
Comfort
Reviews
James,Oct 2026
RSW - RDU
Food
Crew
Boarding
Overall
Entertainment
Comfort
Reviews
James,Oct 2026
RSW - RDU
Food
Crew
Boarding
Overall
Entertainment
Comfort
Reviews
James,Oct 2026
RSW - RDU
Food
Crew
Boarding
Overall
Entertainment
Comfort
Reviews
James,Oct 2026
RSW - RDU
Food
Crew
Boarding
Overall
Entertainment
Comfort
Reviews
James,Oct 2026
RSW - RDU
Food
Crew
Boarding
Overall
Entertainment
Comfort
Reviews
James,Oct 2026
RSW - RDU
Find useful and relevant information for your journey from Orlando to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$45 | Average$96 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$89 | Average$186 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$137 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$191 | Average$403 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$348 | FlexibilityNo cancel fee | On-time69% |