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$346+ Cheap flights from Maine to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — FLO
sep. 2 — sep. 91
mar. 9/2
mar. 9/9
1 adult, Economy
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Cheap flight deals from Maine to Florence

Keep the following information in mind while searching for Maine to Florence flight deals. Data was last updated agosto 28, 2025.

Round-trip from

$346
(American Airlines)
From Maine to Florence
Search Deals

Find flight deals from Maine to Florence

Cheapest flights from Maine to Florence
Explore the most affordable flight options available from Maine to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 28, 2025.

This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/1111:01 amBOS - FLO
2 stops11h 52mAmerican Airlines
sáb. 11/1511:11 amFLO - BOS
2 stops8h 49mAmerican Airlines
Deal found 8/26$346
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1910:00 pmBOS - FLO
2 stops12h 45mAmerican Airlines
lun. 11/2410:29 amFLO - BOS
2 stops9h 47mAmerican Airlines
Deal found 8/26$351
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/256:01 pmBOS - FLO
1 stop6h 12mAmerican Airlines
lun. 9/295:37 pmFLO - BOS
1 stop6h 07mAmerican Airlines
Deal found 8/26$419
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/76:01 pmBOS - FLO
1 stop6h 12mAmerican Airlines
sáb. 9/205:37 pmFLO - BOS
1 stop4h 10mAmerican Airlines
Deal found 8/26$479

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 28, 2025.
Use the filters below to find and compare flights from Maine to Florence that are best for you.

Fly from

Maine

Fly to

Florence

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

mar. 11/11

9:00 pm-9:54 am

2 stops12h 54m

Florence

sáb. 11/15

11:11 am-8:00 pm

2 stops8h 49m

$346

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

mié. 11/19

10:00 pm-10:45 am

2 stops12h 45m

Florence

lun. 11/24

10:29 am-8:16 pm

2 stops9h 47m

$351

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

jue. 9/25

6:01 pm-12:13 am

1 stop6h 12m

Florence

lun. 9/29

5:37 pm-11:44 pm

1 stop6h 07m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/25

Best time to book a flight from Maine to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to Florence

What is the cheapest month to book a flight from Maine to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Maine to Florence, South Carolina (average of $366). Flying from Maine to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Maine to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Maine?

    Most people fly into Florence (FLO) if they book a flight to Florence from Maine. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Maine to Florence, South Carolina?

    Airlines like American Airlines fly from Maine to Florence, South Carolina in about 12h 54m. The time it takes to get you to your destination can typically vary by up to . The distance from Maine to Florence, South Carolina is about 735 mi.

  • Can I find deals for flights from Maine to Florence that include hotel bookings?

    Yes. In addition to deals on Maine to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to Florence.

  • Can I find deals for business class flights from Maine to Florence?

    Yes. Cheapflights offers flight deals from Maine to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Maine to Florence, South Carolina (average of $366). Flying from Maine to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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