$93+ Cheap flights from Maine to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Jun 21 — Jun 281
Round-trip
1 adult, Economy
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Find cheap flights from Maine to South Carolina with Cheapflights
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Maine to South Carolina
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Cheapest flights from Maine to South CarolinaExplore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
Explore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:17 pm
BOS
- CHS
Nonstop2h 33m
JetBlue
Tue 6/236:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/20![JetBlue logo]()
$202
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:30 pm
BOS
- SAV
Nonstop2h 41m
Delta
Mon 6/88:08 pm
SAV
- BOS
1 stop5h 23m
Delta
Deal found 5/20![Delta logo]()
$207
This JetBlue deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:37 am
BOS
- CHS
Nonstop2h 30m
JetBlue
Wed 6/176:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/17![JetBlue logo]()
$207
This Breeze Airways deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:00 am
PWM
- SAV
1 stop4h 43m
Breeze Airways
Wed 9/304:55 pm
SAV
- PWM
1 stop4h 24m
Breeze Airways
Deal found 5/19![Breeze Airways logo]()
$210
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:10 am
BOS
- SAV
Nonstop2h 45m
Delta
Wed 7/82:50 pm
SAV
- BOS
Nonstop2h 40m
Delta
Deal found 5/20![Delta logo]()
$212
This JetBlue deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:28 am
BOS
- CHS
Nonstop2h 31m
JetBlue
Tue 6/166:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/17![JetBlue logo]()
$212
This FlightHub deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:01 am
BOS
- SAV
Nonstop2h 41m
JetBlue
Thu 8/279:43 am
SAV
- BOS
Nonstop2h 22m
JetBlue
Deal found 5/18![JetBlue logo]()
$215
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:06 am
BOS
- SAV
1 stop5h 06m
Delta
Tue 6/306:10 pm
SAV
- BOS
1 stop5h 44m
Delta
Deal found 5/20![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:50 am
BOS
- CHS
Nonstop2h 49m
Delta
Tue 7/76:24 pm
CHS
- BOS
1 stop6h 56m
Delta
Deal found 5/18![Delta logo]()
$217
This SmartFares deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:17 pm
BOS
- CHS
Nonstop2h 33m
JetBlue
Mon 6/156:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/19![JetBlue logo]()
$221
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:15 pm
BOS
- SAV
1 stop6h 15m
Southwest
Tue 6/97:50 am
SAV
- BOS
2 stops10h 10m
Southwest
Deal found 5/18![Southwest logo]()
$222
This Cheapflightsfares deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:50 am
BOS
- CHS
Nonstop2h 30m
JetBlue
Fri 7/105:19 pm
CHS
- BOS
Nonstop2h 23m
JetBlue
Deal found 5/20![JetBlue logo]()
$222
Best flights from Maine to South CarolinaDiscover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
Discover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:30 pm
BOS
- SAV
Nonstop2h 41m
Delta
Tue 6/97:05 pm
SAV
- BOS
1 stop6h 26m
Delta
Deal found 5/21![Delta logo]()
$207
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:00 pm
BOS
- SAV
1 stop4h 52m
United Airlines
Fri 6/123:14 pm
SAV
- BOS
1 stop6h 42m
United Airlines
Deal found 5/17![United Airlines logo]()
$217
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:30 am
BOS
- SAV
2 stops7h 15m
Southwest
Wed 7/1510:50 am
SAV
- BOS
2 stops6h 55m
Southwest
Deal found 5/19![Southwest logo]()
$227
This Breeze Airways deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:00 am
PWM
- SAV
1 stop4h 39m
Breeze Airways
Sat 7/46:35 pm
SAV
- PWM
1 stop4h 20m
Breeze Airways
Deal found 5/18![Breeze Airways logo]()
$241
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:00 am
BOS
- HHH
1 stop6h 26m
American Airlines
Sat 6/133:39 pm
HHH
- BOS
Nonstop2h 38m
American Airlines
Deal found 5/21![American Airlines logo]()
$314
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:17 pm
PWM
- SAV
1 stop5h 03m
JetBlue
Wed 9/27:23 pm
SAV
- PWM
1 stop4h 51m
JetBlue
Deal found 5/21![JetBlue logo]()
$335
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:00 pm
BOS
- SAV
1 stop7h 00m
Delta
Mon 6/88:08 pm
SAV
- BOS
1 stop5h 23m
Delta
Deal found 5/21![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:40 am
BOS
- CHS
Nonstop2h 45m
Delta
Tue 7/71:05 pm
CHS
- BOS
1 stop4h 55m
Delta
Deal found 5/17![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:10 pm
BOS
- SAV
1 stop6h 45m
Southwest
Wed 7/1510:50 am
SAV
- BOS
2 stops6h 55m
Southwest
Deal found 5/17![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:30 pm
BOS
- CHS
1 stop8h 06m
Delta
Wed 6/173:15 pm
CHS
- BOS
Nonstop2h 34m
Delta
Deal found 5/18![Delta logo]()
$222
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:25 am
BOS
- SAV
2 stops9h 50m
Southwest
Tue 7/77:50 am
SAV
- BOS
1 stop4h 20m
Southwest
Deal found 5/18![Southwest logo]()
$252
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:45 am
BOS
- CAE
1 stop4h 11m
United Airlines
Fri 6/267:45 pm
CAE
- BOS
1 stop4h 14m
United Airlines
Deal found 5/18![United Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:25 pm
BOS
- SAV
1 stop6h 00m
Southwest
Sat 6/67:20 pm
SAV
- BOS
1 stop4h 15m
Southwest
Deal found 5/20![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:25 am
BOS
- SAV
Nonstop2h 45m
Delta
Sun 7/195:39 am
SAV
- BOS
1 stop5h 02m
Delta
Deal found 5/18![Delta logo]()
$237
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:35 am
PWM
- SAV
2 stops7h 33m
American Airlines
Sat 10/245:26 am
SAV
- PWM
2 stops7h 06m
American Airlines
Deal found 5/21![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:15 pm
BOS
- SAV
Nonstop2h 47m
Delta
Sun 8/235:35 am
SAV
- BOS
1 stop5h 06m
Delta
Deal found 5/19![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:30 am
BOS
- CAE
2 stops6h 46m
United Airlines
Mon 6/15:41 pm
CAE
- BOS
1 stop5h 40m
United Airlines
Deal found 5/19![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:00 am
BOS
- GSP
1 stop7h 07m
American Airlines
Fri 7/176:00 am
GSP
- BOS
1 stop5h 53m
American Airlines
Deal found 5/21![American Airlines logo]()
$340
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:10 am
BOS
- SAV
Nonstop2h 38m
Delta
Sat 7/116:45 pm
SAV
- BOS
1 stop5h 14m
Delta
Deal found 5/19![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:30 am
BOS
- CAE
1 stop4h 46m
United Airlines
Sat 6/62:29 pm
CAE
- BOS
1 stop7h 27m
United Airlines
Deal found 5/17![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:10 am
BOS
- SAV
Nonstop2h 45m
Delta
Sun 7/56:00 am
SAV
- BOS
1 stop7h 20m
Delta
Deal found 5/21![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:00 pm
BOS
- MYR
1 stop4h 10m
Southwest
Sat 7/114:50 pm
MYR
- BOS
1 stop7h 25m
Southwest
Deal found 5/21![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:30 am
BOS
- CAE
2 stops6h 46m
United Airlines
Mon 6/87:45 pm
CAE
- BOS
1 stop4h 14m
United Airlines
Deal found 5/19![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:45 am
BOS
- CHS
Nonstop2h 31m
Delta
Sun 7/1911:25 am
CHS
- BOS
1 stop6h 12m
Delta
Deal found 5/20![Delta logo]()
$237
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:32 pm
PWM
- CLT
Nonstop2h 29m
American Airlines
Tue 9/87:40 pm
CLT
- PWM
Nonstop2h 20m
American Airlines
Deal found 5/21![American Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:35 am
BOS
- CHS
2 stops10h 35m
Southwest
Tue 7/76:50 pm
CHS
- BOS
1 stop4h 30m
Southwest
Deal found 5/18![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:45 am
BOS
- CHS
Nonstop2h 31m
Delta
Fri 7/103:42 pm
CHS
- BOS
1 stop6h 51m
Delta
Deal found 5/20![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:30 am
BOS
- CAE
2 stops6h 46m
United Airlines
Mon 6/87:45 pm
CAE
- BOS
1 stop4h 14m
United Airlines
Deal found 5/21![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:00 am
BOS
- HHH
1 stop7h 13m
American Airlines
Sat 5/3012:16 pm
HHH
- BOS
Nonstop2h 38m
American Airlines
Deal found 5/21![American Airlines logo]()
$398
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:25 am
PWM
- CLT
1 stop3h 55m
Southwest
Tue 10/206:35 pm
CLT
- PWM
1 stop3h 55m
Southwest
Deal found 5/20![Southwest logo]()
$343
Last-minute flights from Maine to South CarolinaDiscover last-minute flight deals from Maine to South Carolina. Data last updated May 22, 2026 and is based on user searches.
Discover last-minute flight deals from Maine to South Carolina. Data last updated May 22, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:17 pm
BOS
- CHS
Nonstop2h 38m
JetBlue
Mon 6/88:50 pm
CHS
- BOS
Nonstop2h 21m
JetBlue
Deal found 5/19![JetBlue logo]()
$226
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:30 pm
BOS
- SAV
Nonstop2h 41m
Delta
Mon 6/88:08 pm
SAV
- BOS
1 stop5h 23m
Delta
Deal found 5/20![Delta logo]()
$207
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:05 am
BOS
- SAV
1 stop7h 56m
Delta
Sat 8/295:56 pm
SAV
- BOS
Nonstop2h 45m
Delta
Deal found 5/18![Delta logo]()
$222
This JetBlue deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:28 am
BOS
- CHS
Nonstop2h 31m
JetBlue
Tue 6/166:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/17![JetBlue logo]()
$212
This FlightHub deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:01 am
BOS
- SAV
Nonstop2h 41m
JetBlue
Thu 8/279:43 am
SAV
- BOS
Nonstop2h 22m
JetBlue
Deal found 5/18![JetBlue logo]()
$215
This SmartFares deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:17 pm
BOS
- CHS
Nonstop2h 33m
JetBlue
Mon 6/156:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/19![JetBlue logo]()
$221
This Cheapflightsfares deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:17 pm
BOS
- CHS
Nonstop2h 33m
JetBlue
Tue 6/236:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/20![JetBlue logo]()
$202
This JetBlue deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:37 am
BOS
- CHS
Nonstop2h 30m
JetBlue
Wed 6/176:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/17![JetBlue logo]()
$207
This Cheapflightsfares deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:17 pm
BOS
- CHS
Nonstop2h 33m
JetBlue
Tue 6/236:45 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 5/20![JetBlue logo]()
$222
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:06 am
BOS
- SAV
1 stop5h 06m
Delta
Tue 6/306:10 pm
SAV
- BOS
1 stop5h 44m
Delta
Deal found 5/20![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:10 am
BOS
- SAV
Nonstop2h 45m
Delta
Wed 7/82:50 pm
SAV
- BOS
Nonstop2h 40m
Delta
Deal found 5/20![Delta logo]()
$212
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:50 am
BOS
- CHS
Nonstop2h 49m
Delta
Tue 7/76:24 pm
CHS
- BOS
1 stop6h 56m
Delta
Deal found 5/18![Delta logo]()
$217
One-way flights from Maine to South CarolinaSearch for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
Search for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
This Breeze Airways deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:00 am
PWM
- SAV
1 stop4h 39m
Breeze Airways
Deal found 5/20![Breeze Airways logo]()
$93
This Super.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:10 am
BOS
- SAV
Nonstop2h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$112
This Super.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:10 am
BOS
- SAV
Nonstop2h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$113
This Breeze Airways deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
PWM
- SAV
1 stop4h 39m
Breeze Airways
Deal found 5/20![Breeze Airways logo]()
$113
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:10 am
BOS
- SAV
Nonstop2h 45m
Delta
Deal found 5/18![Delta logo]()
$114
This Super.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:05 am
BOS
- CLT
1 stop24h 24m
Frontier
Deal found 5/17![Frontier logo]()
$114
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:50 am
BOS
- CHS
1 stop7h 55m
United Airlines
Deal found 5/20![United Airlines logo]()
$119
This Expedia deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:05 am
BOS
- CLT
1 stop24h 24m
Frontier
Deal found 5/17![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
BOS
- CLT
2 stops15h 35m
Frontier
Deal found 5/17![Frontier logo]()
$121
This Super.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:17 pm
BOS
- CHS
Nonstop2h 33m
JetBlue
Deal found 5/17![JetBlue logo]()
$122
This Cheapflightsfares deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:52 pm
BOS
- CHS
Nonstop2h 31m
JetBlue
Deal found 5/21![JetBlue logo]()
$123
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:30 am
BOS
- SAV
1 stop5h 22m
Delta
Deal found 5/18![Delta logo]()
$124
Find flight deals from Maine to South Carolina
Keep the following information in mind while searching for Maine to South Carolina flight deals. Data was last updated May 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $202 (Cheapflightsfares) |
One-way from | $93 (Breeze Airways) |
Popular in | April |
Cheapest in | August |
Average price | $382 |
Good round-trip deal | $228 or less |
Good one-way deal | $73 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Sat 6/6
2:30 pm-5:11 pm
Nonstop2h 41m
Savannah/Hilton Head
Tue 6/9
7:05 pm-1:31 am
1 stop6h 26m
$207
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Mon 6/8
7:00 pm-11:52 pm
1 stop4h 52m
Savannah/Hilton Head
Fri 6/12
3:14 pm-9:56 pm
1 stop6h 42m
$217
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Fri 6/5
2:00 pm-9:00 pm
1 stop7h 00m
Savannah/Hilton Head
Mon 6/8
8:08 pm-1:31 am
1 stop5h 23m
$217
BostonCharleston
BOS - CHS
BOSCHS
Boston Logan Intl
Wed 7/1
8:40 am-11:25 am
Nonstop2h 45m
Charleston
Tue 7/7
1:05 pm-6:00 pm
1 stop4h 55m
$217
BostonCharleston
BOS - CHS
BOSCHS
Boston Logan Intl
Wed 6/10
4:30 pm-12:36 am
1 stop8h 06m
Charleston
Wed 6/17
3:15 pm-5:49 pm
Nonstop2h 34m
$222
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Wed 7/8
10:30 am-5:45 pm
2 stops7h 15m
Savannah/Hilton Head
Wed 7/15
10:50 am-5:45 pm
2 stops6h 55m
$227
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Thu 7/16
11:25 am-2:10 pm
Nonstop2h 45m
Savannah/Hilton Head
Sun 7/19
5:39 am-10:41 am
1 stop5h 02m
$237
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Sun 8/16
3:15 pm-6:02 pm
Nonstop2h 47m
Savannah/Hilton Head
Sun 8/23
5:35 am-10:41 am
1 stop5h 06m
$237
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Sat 7/4
7:10 am-9:48 am
Nonstop2h 38m
Savannah/Hilton Head
Sat 7/11
6:45 pm-11:59 pm
1 stop5h 14m
$237
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Mon 6/29
7:10 am-9:55 am
Nonstop2h 45m
Savannah/Hilton Head
Sun 7/5
6:00 am-1:20 pm
1 stop7h 20m
$237
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Maine to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Maine with our price prediction graph.
PWM-SAV
BOS-SAV
BOS-CLT
BOS-CHS
BOS-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Maine to South Carolina
USME-USSC
PWM-SAV
BOS-SAV
BOS-CLT
BOS-CHS
What is the cheapest month to book a flight from Maine to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Maine to South Carolina (average of $66). Flying from Maine to South Carolina in April is currently the most expensive (average of $148). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ME to SC?
Find hourly flight availability from Maine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 22, 2026.
It’s optimal to fly from Maine to South Carolina in the morning. By choosing this option you can save up to 57% on the cost of your flight, compared to a flight at noon.
How much does it cost to fly round-trip from Maine to South Carolina?
How far ahead should I book a flight from Maine to South Carolina?
The price you pay for your flight from Maine to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 22, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Maine to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Boarding
8.3
Entertainment
6.7
Comfort
8.2
Overall
8.1
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Boarding
8.3
Entertainment
6.7
Comfort
8.2
Overall
8.1
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Boarding
8.3
Entertainment
6.7
Comfort
8.2
Overall
8.1
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Boarding
8.3
Entertainment
6.7
Comfort
8.2
Overall
8.1
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Boarding
8.3
Entertainment
6.7
Comfort
8.2
Overall
8.1
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Boarding
8.3
Entertainment
6.7
Comfort
8.2
Overall
8.1
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Maine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Maine to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Maine to South Carolina by cabin class
Find flights from Maine to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Maine and South Carolina flights
Browse other Maine and South Carolina flight options. Last updated on May 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Maine after your stay in South Carolina
Maine to South Carolina flights
Consider these flights traveling from Maine to South Carolina.
Top 5 airlines flying from Maine to South Carolina
Discover the top 5 airlines that operate flights from Maine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$102 | Average$216 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$138 | Average$347 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$393 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$262 | Average$419 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$277 | Average$459 | FlexibilityNo cancel fee | On-time69% |