$57+ Cheap flights from Maine to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Find cheap flights from Maine to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Maine to South Carolina
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Cheapest flights from Maine to South CarolinaExplore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:35 pm -
Nonstop2h 43m
Mon 1/251:55 pm -
Nonstop2h 25m
Deal found 10/17![Breeze Airways logo]()
$136
This Breeze Airways deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:35 pm -
Nonstop2h 43m
Fri 1/221:55 pm -
Nonstop2h 25m
Deal found 10/15![Breeze Airways logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:35 pm -
Nonstop2h 43m
Fri 12/252:30 pm -
Nonstop2h 25m
Deal found 10/14![Breeze Airways logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 pm -
Nonstop2h 43m
Fri 11/62:30 pm -
Nonstop2h 25m
Deal found 10/14![Breeze Airways logo]()
$185
This Breeze Airways deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:35 pm -
Nonstop2h 43m
Fri 11/132:30 pm -
Nonstop2h 25m
Deal found 10/16![Breeze Airways logo]()
$223
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:25 am -
1 stop4h 30m
Sat 1/166:30 pm -
1 stop4h 25m
Deal found 10/19![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:45 pm -
1 stop5h 40m
Wed 1/1310:55 am -
2 stops10h 45m
Deal found 10/19![Southwest logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:12 pm -
1 stop17h 02m
Fri 1/86:12 pm -
1 stop23h 39m
Deal found 10/16![Breeze Airways logo]()
$298
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/154:52 pm -
1 stop5h 23m
Wed 1/66:00 am -
1 stop6h 36m
Deal found 10/14![Delta logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:12 pm -
1 stop17h 02m
Tue 12/84:08 pm -
1 stop17h 00m
Deal found 10/16![Breeze Airways logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop5h 30m
Sat 11/1410:43 am -
1 stop3h 41m
Deal found 10/15![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:50 pm -
2 stops7h 03m
Sat 11/145:44 pm -
1 stop5h 47m
Deal found 10/14![Delta logo]()
$344
Best flights from Maine to South CarolinaDiscover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This Breeze Airways deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:35 pm -
Nonstop2h 43m
Fri 1/221:55 pm -
Nonstop2h 25m
Deal found 10/16![Breeze Airways logo]()
$188
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:45 pm -
1 stop5h 40m
Wed 1/138:00 am -
1 stop6h 40m
Deal found 10/19![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:06 pm -
2 stops9h 43m
Wed 1/66:00 am -
1 stop6h 36m
Deal found 10/14![Delta logo]()
$316
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/59:10 am -
1 stop4h 56m
Thu 1/710:14 am -
2 stops9h 07m
Deal found 10/14![United Airlines logo]()
$342
This Breeze Airways deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/85:00 pm -
Nonstop2h 43m
Mon 3/151:55 pm -
Nonstop2h 25m
Deal found 10/14![Breeze Airways logo]()
$213
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop6h 30m
Wed 11/46:43 pm -
1 stop4h 16m
Deal found 10/16![American Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2912:50 pm -
1 stop6h 50m
Tue 2/28:30 am -
1 stop6h 10m
Deal found 10/18![Southwest logo]()
$313
This Breeze Airways deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:35 pm -
Nonstop2h 43m
Mon 11/162:30 pm -
Nonstop2h 25m
Deal found 10/19![Breeze Airways logo]()
$298
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:00 am -
2 stops8h 10m
Mon 1/185:00 pm -
1 stop6h 06m
Deal found 10/18![Delta logo]()
$344
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/107:10 am -
1 stop6h 56m
Wed 2/176:05 am -
2 stops8h 36m
Deal found 10/18![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:00 am -
2 stops8h 10m
Tue 1/125:10 pm -
1 stop5h 13m
Deal found 10/18![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:25 am -
2 stops11h 55m
Sat 1/1610:30 am -
2 stops12h 25m
Deal found 10/19![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:30 am -
1 stop4h 29m
Mon 11/27:54 pm -
1 stop4h 05m
Deal found 10/14![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
2 stops10h 28m
Sat 1/166:00 am -
2 stops7h 53m
Deal found 10/18![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2410:39 am -
2 stops7h 25m
Mon 3/13:57 pm -
1 stop7h 19m
Deal found 10/16![American Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:10 pm -
1 stop4h 14m
Mon 11/28:32 pm -
2 stops19h 52m
Deal found 10/14![Breeze Airways logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2412:37 pm -
1 stop5h 36m
Wed 3/31:00 pm -
1 stop4h 29m
Deal found 10/18![American Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/72:00 pm -
2 stops7h 58m
Tue 1/125:45 pm -
1 stop5h 38m
Deal found 10/17![Delta logo]()
$366
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:20 am -
1 stop4h 50m
Sat 11/148:25 am -
1 stop6h 20m
Deal found 10/18![Southwest logo]()
$416
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:46 am -
2 stops11h 16m
Sat 11/1410:16 am -
2 stops8h 33m
Deal found 10/14![United Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/211:20 pm -
1 stop6h 55m
Fri 1/2211:20 am -
1 stop5h 39m
Deal found 10/16![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:24 pm -
2 stops6h 05m
Wed 11/188:07 am -
2 stops9h 23m
Deal found 10/17![American Airlines logo]()
$465
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/611:25 am -
2 stops9h 38m
Sat 1/95:50 am -
1 stop4h 57m
Deal found 10/18![United Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/61:10 pm -
2 stops8h 35m
Thu 4/86:50 am -
2 stops9h 30m
Deal found 10/18![Southwest logo]()
$434
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/72:35 pm -
1 stop6h 07m
Sat 1/911:20 am -
1 stop5h 39m
Deal found 10/17![Delta logo]()
$387
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:07 am -
2 stops9h 37m
Tue 11/104:17 pm -
1 stop5h 19m
Deal found 10/16![American Airlines logo]()
$473
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:30 am -
1 stop6h 36m
Mon 1/113:23 pm -
1 stop5h 40m
Deal found 10/14![United Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:35 am -
2 stops7h 30m
Sun 1/108:00 am -
1 stop4h 10m
Deal found 10/17![Southwest logo]()
$442
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:50 pm -
1 stop4h 43m
Fri 11/136:57 pm -
1 stop4h 24m
Deal found 10/16![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 am -
2 stops8h 53m
Thu 11/53:29 pm -
1 stop6h 22m
Deal found 10/14![United Airlines logo]()
$443
Last-minute flights from Maine to South CarolinaDiscover last-minute flight deals from Maine to South Carolina. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Maine to South Carolina. Data last updated October 19, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:10 pm -
1 stop4h 14m
Mon 11/28:32 pm -
2 stops19h 52m
Deal found 10/14![Breeze Airways logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:35 pm -
Nonstop2h 43m
Mon 11/22:30 pm -
Nonstop2h 25m
Deal found 10/16![Breeze Airways logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:09 pm -
2 stops16h 29m
Mon 11/22:30 pm -
Nonstop2h 25m
Deal found 10/17![Breeze Airways logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:09 pm -
2 stops16h 29m
Wed 11/46:00 am -
1 stop11h 51m
Deal found 10/16![Breeze Airways logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 pm -
Nonstop2h 43m
Fri 11/62:30 pm -
Nonstop2h 25m
Deal found 10/14![Breeze Airways logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 pm -
Nonstop2h 43m
Wed 11/46:00 am -
1 stop11h 51m
Deal found 10/14![Breeze Airways logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 pm -
Nonstop2h 43m
Thu 11/52:13 pm -
1 stop18h 55m
Deal found 10/14![Breeze Airways logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:09 pm -
2 stops39h 29m
Fri 11/62:30 pm -
Nonstop2h 25m
Deal found 10/14![Multiple Airlines logo]()
$280
This Breeze Airways deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:35 pm -
Nonstop2h 43m
Fri 11/132:30 pm -
Nonstop2h 25m
Deal found 10/16![Breeze Airways logo]()
$223
This Breeze Airways deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:35 pm -
Nonstop2h 43m
Mon 11/162:30 pm -
Nonstop2h 25m
Deal found 10/16![Breeze Airways logo]()
$278
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop5h 30m
Sat 11/1410:43 am -
1 stop3h 41m
Deal found 10/15![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:50 pm -
2 stops7h 03m
Sat 11/145:44 pm -
1 stop5h 47m
Deal found 10/14![Delta logo]()
$344
One-way flights from Maine to South CarolinaSearch for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:35 pm -
Nonstop2h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Breeze Airways logo]()
$57
This Breeze Airways deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 pm -
Nonstop2h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Breeze Airways logo]()
$119
This Breeze Airways deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:35 pm -
Nonstop2h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Breeze Airways logo]()
$129
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:45 pm -
1 stop5h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$134
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:01 am -
1 stop4h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![American Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/53:10 pm -
1 stop4h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Breeze Airways logo]()
$168
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:46 am -
1 stop4h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![United Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:54 pm -
1 stop21h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Allegiant Air logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:09 pm -
2 stops39h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:10 pm -
1 stop25h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Breeze Airways logo]()
$190
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:28 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Delta logo]()
$198
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:53 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Delta logo]()
$206
Find flight deals from Maine to South Carolina
Keep the following information in mind while searching for Maine to South Carolina flight deals. Data was last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $122 (Kiwi.com) |
One-way from | $57 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $380 |
Good round-trip deal | $375 or less |
Good one-way deal | $104 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandCharleston
PWM Portland - CHS Charleston
PWMCHS
Portland
Fri 11/6
5:35 pm-8:18 pm
Nonstop2h 43m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Tue 12/1
12:45 pm-6:25 pm
1 stop5h 40m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$134
BangorGreenville
BGR Bangor - GSP Greenville
BGRGSP
Bangor
Thu 11/12
4:54 pm-2:42 pm
1 stop21h 48m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$178
PortlandCharleston
PWM Portland - CHS Charleston
PWMCHS
Portland
Tue 12/1
5:09 pm-8:38 am
2 stops39h 29m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
PortlandCharleston
PWM Portland - CHS Charleston
PWMCHS
Portland
Mon 12/21
5:35 pm-8:18 pm
Nonstop2h 43m
Charleston
Fri 1/22
1:55 pm-4:20 pm
Nonstop2h 25m
$188
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 12/8
4:53 pm-9:49 pm
1 stop4h 56m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$198
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Fri 11/6
5:28 pm-10:24 pm
1 stop4h 56m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$198
PortlandCharleston
PWM Portland - CHS Charleston
PWMCHS
Portland
Mon 3/8
5:00 pm-7:43 pm
Nonstop2h 43m
Charleston
Mon 3/15
1:55 pm-4:20 pm
Nonstop2h 25m
$213
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 12/8
6:00 am-4:53 pm
2 stops10h 53m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$218
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Mon 11/9
11:07 am-6:17 pm
1 stop7h 10m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Maine to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Maine with our price prediction graph.
PWM-CHS
PWM-MYR
BGR-GSP
PWM-CAE
BGR-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Maine to South Carolina
USME-USSC
PWM-CHS
PWM-MYR
BGR-GSP
PWM-CAE
What is the cheapest month to book a flight from Maine to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Maine to South Carolina (average of $266). Flying from Maine to South Carolina in November is currently the most expensive (average of $431). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ME to SC?
Find hourly flight availability from Maine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 19, 2026.
It’s optimal to fly from Maine to South Carolina in the evening. By choosing this option you can save up to 44% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Maine to South Carolina?
Airfare is below average for this route at the moment.
Maine to South Carolina flights typically cost between $353 and $457 in January.The cheapest round-trip price found within the last 5 days was $122 on Breeze Airways (Jan 8-Jan 11).
How far ahead should I book a flight from Maine to South Carolina?
The price you pay for your flight from Maine to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 19, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Maine to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Overall
8.2
Boarding
8.4
Comfort
8.2
Food
6.7
Entertainment
6.8
Reviews
1 / 19
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Overall
8.2
Boarding
8.4
Comfort
8.2
Food
6.7
Entertainment
6.8
Reviews
1 / 19
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Overall
8.2
Boarding
8.4
Comfort
8.2
Food
6.7
Entertainment
6.8
Reviews
1 / 19
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Overall
8.2
Boarding
8.4
Comfort
8.2
Food
6.7
Entertainment
6.8
Reviews
1 / 19
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Overall
8.2
Boarding
8.4
Comfort
8.2
Food
6.7
Entertainment
6.8
Reviews
1 / 19
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Overall
8.2
Boarding
8.4
Comfort
8.2
Food
6.7
Entertainment
6.8
Reviews
1 / 19
10.0
ExcellentJames,Oct 2026
RSW - RDU
Related info for your journey
Find useful and relevant information for your journey from Maine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Maine to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Maine to South Carolina by cabin class
Find flights from Maine to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Maine and South Carolina flights
Browse other Maine and South Carolina flight options. Last updated on October 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Maine after your stay in South Carolina
Maine to South Carolina flights
Consider these flights traveling from Maine to South Carolina.
Top 5 airlines flying from Maine to South Carolina
Discover the top 5 airlines that operate flights from Maine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$113 | Average$286 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$138 | Average$379 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$368 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$223 | Average$415 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$229 | Average$436 | FlexibilityNo cancel fee | On-time63% |