$58+ Cheap flights from Maine to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Aug 8 — Aug 151
Round-trip
1 adult, Economy
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Find cheap flights from Maine to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Maine to South Carolina
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Cheapest flights from Maine to South CarolinaExplore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
Explore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Wed 9/302:09 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Mon 8/313:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/7![Breeze Airways logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Mon 8/313:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$138
This Breeze Airways deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/8![Breeze Airways logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Fri 8/213:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/7![Breeze Airways logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/116:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/5![Breeze Airways logo]()
$172
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/219:25 am
BOS
- CHS
1 stop5h 02m
United Airlines
Wed 7/2910:13 am
CHS
- BOS
2 stops6h 25m
United Airlines
Deal found 7/5![United Airlines logo]()
$182
This Breeze Airways deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:30 pm
PWM
- CHS
Nonstop2h 43m
Breeze Airways
Mon 9/282:25 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/5![Breeze Airways logo]()
$183
This SmartFares deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:16 pm
BOS
- SAV
Nonstop2h 45m
JetBlue
Sun 8/238:44 pm
SAV
- BOS
Nonstop2h 31m
JetBlue
Deal found 7/4![JetBlue logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Thu 8/276:25 pm
MYR
- PWM
1 stop4h 14m
Breeze Airways
Deal found 7/5![Breeze Airways logo]()
$201
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:45 am
BOS
- CHS
1 stop4h 22m
United Airlines
Sat 7/2510:00 am
CHS
- BOS
1 stop7h 24m
United Airlines
Deal found 7/8![United Airlines logo]()
$201
Best flights from Maine to South CarolinaDiscover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
Discover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
This Breeze Airways deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/9![Breeze Airways logo]()
$143
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:10 pm
BOS
- GSP
1 stop5h 03m
Delta
Thu 8/205:20 pm
GSP
- BOS
1 stop6h 21m
Delta
Deal found 7/9![Delta logo]()
$211
This JetBlue deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:16 pm
BOS
- SAV
Nonstop2h 45m
JetBlue
Tue 9/19:38 am
SAV
- BOS
Nonstop2h 24m
JetBlue
Deal found 7/8![JetBlue logo]()
$217
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:30 am
PWM
- CHS
1 stop4h 35m
United Airlines
Tue 11/33:27 pm
CHS
- PWM
2 stops8h 32m
United Airlines
Deal found 7/7![United Airlines logo]()
$222
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:20 pm
BOS
- CHS
1 stop5h 00m
Southwest
Tue 9/157:35 am
CHS
- BOS
2 stops8h 25m
Southwest
Deal found 7/8![Southwest logo]()
$234
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:46 pm
PWM
- MYR
1 stop4h 31m
American Airlines
Sat 8/153:56 pm
MYR
- PWM
1 stop6h 19m
American Airlines
Deal found 7/4![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:30 am
BOS
- GSP
1 stop4h 32m
Delta
Mon 8/172:51 pm
GSP
- BOS
1 stop7h 34m
Delta
Deal found 7/8![Delta logo]()
$211
This JetBlue deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:45 am
BOS
- CHS
Nonstop2h 30m
JetBlue
Tue 8/116:40 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 7/8![JetBlue logo]()
$247
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:25 am
BOS
- SAV
Nonstop2h 45m
Delta
Sat 9/56:46 pm
SAV
- BOS
1 stop5h 13m
Delta
Deal found 7/8![Delta logo]()
$227
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am
BOS
- CAE
1 stop4h 02m
United Airlines
Sat 10/105:37 pm
CAE
- BOS
1 stop5h 47m
United Airlines
Deal found 7/5![United Airlines logo]()
$251
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:50 am
BOS
- GSP
2 stops9h 05m
Southwest
Mon 8/177:00 am
GSP
- BOS
2 stops10h 05m
Southwest
Deal found 7/8![Southwest logo]()
$275
This JetBlue deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:01 am
BOS
- CHS
1 stop5h 10m
JetBlue
Tue 8/256:40 pm
CHS
- BOS
Nonstop2h 24m
JetBlue
Deal found 7/4![JetBlue logo]()
$252
This Breeze Airways deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:05 pm
PWM
- CHS
1 stop5h 54m
Breeze Airways
Wed 9/302:09 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:45 am
BOS
- CHS
1 stop4h 26m
United Airlines
Thu 8/63:34 pm
CHS
- BOS
1 stop6h 19m
United Airlines
Deal found 7/8![United Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:50 am
BOS
- SAV
1 stop4h 44m
Delta
Sat 9/265:55 pm
SAV
- BOS
Nonstop2h 37m
Delta
Deal found 7/8![Delta logo]()
$247
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:25 am
BOS
- SAV
1 stop7h 00m
Southwest
Thu 9/174:10 pm
SAV
- BOS
1 stop6h 20m
Southwest
Deal found 7/7![Southwest logo]()
$277
This JetBlue deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:27 pm
BOS
- CHS
Nonstop2h 33m
JetBlue
Thu 9/1011:05 am
CHS
- BOS
1 stop5h 54m
JetBlue
Deal found 7/7![JetBlue logo]()
$252
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:05 am
BOS
- CHS
1 stop6h 53m
United Airlines
Wed 8/2610:19 am
CHS
- BOS
2 stops6h 23m
United Airlines
Deal found 7/4![United Airlines logo]()
$262
This JetBlue deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:16 am
BOS
- CHS
1 stop4h 52m
JetBlue
Thu 8/2710:58 am
CHS
- BOS
1 stop8h 01m
JetBlue
Deal found 7/4![JetBlue logo]()
$257
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:25 am
BOS
- SAV
2 stops11h 00m
Southwest
Sat 9/2612:50 pm
SAV
- BOS
2 stops8h 50m
Southwest
Deal found 7/8![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:30 am
BOS
- SAV
1 stop5h 07m
Delta
Fri 9/116:55 pm
SAV
- BOS
1 stop4h 22m
Delta
Deal found 7/8![Delta logo]()
$262
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:45 am
BOS
- CHS
2 stops8h 31m
United Airlines
Wed 7/296:00 am
CHS
- BOS
2 stops11h 24m
United Airlines
Deal found 7/8![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:00 am
BOS
- SAV
1 stop5h 25m
Delta
Tue 7/211:57 pm
SAV
- BOS
1 stop7h 03m
Delta
Deal found 7/5![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:25 am
BOS
- SAV
2 stops11h 00m
Southwest
Tue 8/256:45 am
SAV
- BOS
2 stops9h 15m
Southwest
Deal found 7/4![Southwest logo]()
$297
This JetBlue deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:44 am
BOS
- CHS
Nonstop2h 31m
JetBlue
Thu 9/1012:45 pm
CHS
- BOS
Nonstop2h 36m
JetBlue
Deal found 7/7![JetBlue logo]()
$287
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:45 am
BOS
- GSP
2 stops7h 47m
United Airlines
Fri 8/147:47 pm
GSP
- BOS
1 stop4h 12m
United Airlines
Deal found 7/8![United Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/243:10 pm
BOS
- SAV
1 stop6h 07m
Delta
Sun 7/268:14 pm
SAV
- BOS
1 stop5h 06m
Delta
Deal found 7/6![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:40 pm
PWM
- CHS
1 stop4h 50m
Southwest
Tue 9/221:25 pm
CHS
- PWM
1 stop3h 50m
Southwest
Deal found 7/7![Southwest logo]()
$306
This Breeze Airways deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Sun 7/266:25 pm
MYR
- PWM
1 stop4h 14m
Breeze Airways
Deal found 7/4![Breeze Airways logo]()
$413
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:05 am
PWM
- MYR
1 stop7h 28m
Delta
Tue 9/16:00 am
MYR
- PWM
2 stops10h 01m
Delta
Deal found 7/8![Delta logo]()
$269
Last-minute flights from Maine to South CarolinaDiscover last-minute flight deals from Maine to South Carolina. Data last updated July 9, 2026 and is based on user searches.
Discover last-minute flight deals from Maine to South Carolina. Data last updated July 9, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/219:25 am
BOS
- CHS
1 stop5h 02m
United Airlines
Wed 7/2910:13 am
CHS
- BOS
2 stops6h 25m
United Airlines
Deal found 7/5![United Airlines logo]()
$182
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:45 am
BOS
- CHS
1 stop4h 22m
United Airlines
Sat 7/2510:00 am
CHS
- BOS
1 stop7h 24m
United Airlines
Deal found 7/8![United Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/116:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/5![Breeze Airways logo]()
$172
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:30 am
BOS
- SAV
1 stop6h 46m
United Airlines
Wed 8/1912:59 pm
SAV
- BOS
1 stop6h 20m
United Airlines
Deal found 7/7![United Airlines logo]()
$203
This Breeze Airways deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/8![Breeze Airways logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Fri 8/213:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/7![Breeze Airways logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/7![Breeze Airways logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Thu 8/276:25 pm
MYR
- PWM
1 stop4h 14m
Breeze Airways
Deal found 7/5![Breeze Airways logo]()
$201
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Mon 8/243:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/7![Breeze Airways logo]()
$183
This SmartFares deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:16 pm
BOS
- SAV
Nonstop2h 45m
JetBlue
Sun 8/238:44 pm
SAV
- BOS
Nonstop2h 31m
JetBlue
Deal found 7/4![JetBlue logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Mon 8/313:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Mon 8/313:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$138
One-way flights from Maine to South CarolinaSearch for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
Search for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 7/4![Breeze Airways logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 7/7![Breeze Airways logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 7/9![Breeze Airways logo]()
$88
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:20 pm
BOS
- MYR
1 stop5h 50m
Southwest
Deal found 7/8![Southwest logo]()
$89
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:19 am
BOS
- SAV
1 stop6h 57m
United Airlines
Deal found 7/7![United Airlines logo]()
$97
This Breeze Airways deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$99
This Breeze Airways deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:30 pm
PWM
- CHS
Nonstop2h 43m
Breeze Airways
Deal found 7/8![Breeze Airways logo]()
$99
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:25 am
BOS
- SAV
1 stop4h 45m
Southwest
Deal found 7/7![Southwest logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 7/6![Breeze Airways logo]()
$103
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:19 am
BOS
- SAV
1 stop6h 57m
United Airlines
Deal found 7/8![United Airlines logo]()
$104
This Breeze Airways deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 7/8![Breeze Airways logo]()
$104
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:00 am
BOS
- MYR
1 stop8h 10m
Southwest
Deal found 7/8![Southwest logo]()
$106
Find flight deals from Maine to South Carolina
Keep the following information in mind while searching for Maine to South Carolina flight deals. Data was last updated July 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $117 (Kiwi.com) |
One-way from | $58 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $422 |
Good round-trip deal | $184 or less |
Good one-way deal | $119 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Tue 8/18
8:00 am-10:35 am
Nonstop2h 35m
Charleston
Tue 8/25
6:54 pm-9:19 pm
Nonstop2h 25m
$143
BostonGreenville
BOS - GSP
BOSGSP
Boston Logan Intl
Fri 8/14
1:10 pm-6:13 pm
1 stop5h 03m
Greenville
Thu 8/20
5:20 pm-11:41 pm
1 stop6h 21m
$211
BostonGreenville
BOS - GSP
BOSGSP
Boston Logan Intl
Sat 8/15
5:30 am-10:02 am
1 stop4h 32m
Greenville
Mon 8/17
2:51 pm-10:25 pm
1 stop7h 34m
$211
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Sat 8/29
5:16 pm-8:01 pm
Nonstop2h 45m
Savannah/Hilton Head
Tue 9/1
9:38 am-12:02 pm
Nonstop2h 24m
$217
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Thu 10/29
5:30 am-10:05 am
1 stop4h 35m
Charleston
Tue 11/3
3:27 pm-11:59 pm
2 stops8h 32m
$222
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Fri 8/28
11:25 am-2:10 pm
Nonstop2h 45m
Savannah/Hilton Head
Sat 9/5
6:46 pm-11:59 pm
1 stop5h 13m
$227
BostonCharleston
BOS - CHS
BOSCHS
Boston Logan Intl
Sat 9/12
2:20 pm-7:20 pm
1 stop5h 00m
Charleston
Tue 9/15
7:35 am-4:00 pm
2 stops8h 25m
$234
Quickest round-trip
BostonCharleston
BOS - CHS
BOSCHS
Boston Logan Intl
Wed 8/5
9:45 am-12:15 pm
Nonstop2h 30m
Charleston
Tue 8/11
6:40 pm-9:04 pm
Nonstop2h 24m
$247
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Tue 9/22
6:50 am-11:34 am
1 stop4h 44m
Savannah/Hilton Head
Sat 9/26
5:55 pm-8:32 pm
Nonstop2h 37m
$247
BostonColumbia
BOS - CAE
BOSCAE
Boston Logan Intl
Wed 10/7
5:45 am-9:47 am
1 stop4h 02m
Columbia Metropolitan
Sat 10/10
5:37 pm-11:24 pm
1 stop5h 47m
$251
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Maine to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Maine with our price prediction graph.
PWM-CHS
BOS-GSP
BOS-SAV
BOS-CHS
PWM-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Maine to South Carolina
USME-USSC
PWM-CHS
BOS-GSP
BOS-SAV
BOS-CHS
What is the cheapest month to book a flight from Maine to South Carolina?
Currently, June is the cheapest month in which you can book a flight from Maine to South Carolina (average of $73). Flying from Maine to South Carolina in April is currently the most expensive (average of $148). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ME to SC?
Find hourly flight availability from Maine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 9, 2026.
It’s optimal to fly from Maine to South Carolina in the morning. By choosing this option you can save up to 46% on the cost of your flight, compared to a flight at noon.
How much does it cost to fly round-trip from Maine to South Carolina?
How far ahead should I book a flight from Maine to South Carolina?
The price you pay for your flight from Maine to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 30 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 9, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Maine to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.7
Overall
8.2
Comfort
8.2
Boarding
8.4
Crew
8.8
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Overall
8.2
Comfort
8.2
Boarding
8.4
Crew
8.8
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Overall
8.2
Comfort
8.2
Boarding
8.4
Crew
8.8
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Overall
8.2
Comfort
8.2
Boarding
8.4
Crew
8.8
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Overall
8.2
Comfort
8.2
Boarding
8.4
Crew
8.8
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Overall
8.2
Comfort
8.2
Boarding
8.4
Crew
8.8
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Maine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Maine to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Maine to South Carolina by cabin class
Find flights from Maine to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Maine and South Carolina flights
Browse other Maine and South Carolina flight options. Last updated on July 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Maine after your stay in South Carolina
Maine to South Carolina flights
Consider these flights traveling from Maine to South Carolina.
Top 5 airlines flying from Maine to South Carolina
Discover the top 5 airlines that operate flights from Maine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$103 | Average$265 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$118 | Average$372 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$223 | Average$392 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$439 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$277 | Average$419 | FlexibilityNo cancel fee | On-time69% |