$110+ Cheap flights from Maine to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Sep 29 — Oct 61
Round-trip
1 adult, Economy
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Find cheap flights from Maine to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Maine to South CarolinaExplore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
Explore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:25 pm -
1 stop5h 32m
Tue 11/102:40 pm -
Nonstop2h 35m
Deal found 8/28![Delta logo]()
$209
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:30 am -
1 stop6h 08m
Wed 11/116:00 am -
1 stop6h 25m
Deal found 8/29![Delta logo]()
$219
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:30 am -
2 stops7h 15m
Wed 11/116:55 pm -
1 stop5h 51m
Deal found 8/29![United Airlines logo]()
$224
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:45 am -
2 stops10h 50m
Sat 10/316:35 am -
2 stops11h 30m
Deal found 8/28![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:35 am -
2 stops14h 20m
Tue 11/106:35 am -
1 stop7h 05m
Deal found 8/28![Southwest logo]()
$230
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:20 am -
2 stops7h 45m
Tue 11/108:00 am -
2 stops14h 10m
Deal found 8/29![Southwest logo]()
$235
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:32 am -
1 stop5h 07m
Sun 9/61:03 pm -
1 stop6h 00m
Deal found 8/25![American Airlines logo]()
$247
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:13 pm -
1 stop6h 05m
Thu 9/107:00 am -
1 stop5h 47m
Deal found 8/26![United Airlines logo]()
$248
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:12 am -
1 stop7h 26m
Sat 11/142:33 pm -
1 stop6h 11m
Deal found 8/28![American Airlines logo]()
$249
This Cheapflightsfares deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:50 pm -
Nonstop2h 52m
Fri 11/133:40 pm -
Nonstop2h 28m
Deal found 8/27![JetBlue logo]()
$250
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am -
1 stop5h 38m
Mon 10/55:59 pm -
1 stop4h 27m
Deal found 8/25![Delta logo]()
$253
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:10 am -
2 stops9h 55m
Mon 11/97:25 pm -
1 stop4h 25m
Deal found 8/28![Southwest logo]()
$254
Best flights from Maine to South CarolinaDiscover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
Discover carefully curated flight deals from Maine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:30 am -
1 stop6h 08m
Wed 11/116:00 am -
1 stop6h 25m
Deal found 8/29![Delta logo]()
$219
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:38 am -
2 stops9h 19m
Sat 10/317:54 pm -
1 stop4h 05m
Deal found 8/29![United Airlines logo]()
$266
This Breeze Airways deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 am -
1 stop4h 19m
Sun 9/205:55 pm -
1 stop4h 24m
Deal found 8/25![Breeze Airways logo]()
$304
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop4h 25m
Tue 10/1312:29 pm -
1 stop5h 27m
Deal found 8/29![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:20 am -
1 stop4h 25m
Mon 11/27:35 pm -
1 stop4h 15m
Deal found 8/25![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:50 am -
1 stop5h 49m
Mon 10/267:14 pm -
1 stop6h 06m
Deal found 8/25![Delta logo]()
$253
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:50 am -
Nonstop2h 52m
Wed 11/116:00 am -
1 stop5h 25m
Deal found 8/25![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:38 am -
1 stop6h 38m
Wed 10/2811:19 am -
1 stop4h 31m
Deal found 8/26![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:25 am -
1 stop4h 40m
Wed 9/95:05 pm -
1 stop4h 25m
Deal found 8/29![Southwest logo]()
$328
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:38 am -
2 stops7h 22m
Fri 10/24:58 pm -
1 stop7h 56m
Deal found 8/25![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:39 am -
1 stop4h 39m
Fri 10/233:39 pm -
1 stop6h 29m
Deal found 8/25![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:35 am -
1 stop4h 40m
Tue 10/61:30 pm -
2 stops9h 15m
Deal found 8/27![Southwest logo]()
$332
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:56 pm -
1 stop5h 02m
Tue 9/155:10 am -
2 stops5h 33m
Deal found 8/29![American Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am -
1 stop7h 18m
Tue 11/172:46 pm -
Nonstop2h 23m
Deal found 8/28![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
2 stops8h 50m
Thu 9/246:50 pm -
1 stop6h 04m
Deal found 8/27![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:10 pm -
1 stop4h 50m
Mon 11/97:35 pm -
1 stop4h 15m
Deal found 8/27![Southwest logo]()
$345
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:10 am -
Nonstop2h 34m
Wed 11/113:15 pm -
1 stop6h 13m
Deal found 8/27![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:20 pm -
1 stop4h 10m
Wed 11/1110:45 am -
2 stops11h 00m
Deal found 8/26![Southwest logo]()
$350
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:00 pm -
1 stop6h 22m
Sat 11/1411:31 am -
Nonstop2h 24m
Deal found 8/27![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops6h 29m
Wed 1/611:56 am -
2 stops6h 00m
Deal found 8/29![American Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:55 am -
1 stop9h 28m
Sat 11/149:07 am -
2 stops9h 32m
Deal found 8/29![United Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:35 am -
1 stop4h 25m
Tue 10/206:40 am -
2 stops9h 25m
Deal found 8/25![Southwest logo]()
$352
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:00 am -
1 stop5h 16m
Sun 10/255:00 am -
1 stop4h 23m
Deal found 8/28![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:40 pm -
1 stop6h 07m
Wed 1/65:45 pm -
1 stop7h 13m
Deal found 8/29![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:23 pm -
1 stop4h 48m
Tue 9/1510:19 am -
2 stops6h 29m
Deal found 8/26![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:20 am -
2 stops9h 40m
Fri 11/206:40 am -
1 stop7h 05m
Deal found 8/29![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:50 am -
Nonstop2h 30m
Wed 9/233:15 pm -
Nonstop2h 32m
Deal found 8/29![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:45 am -
2 stops9h 18m
Wed 9/237:47 pm -
1 stop4h 12m
Deal found 8/28![United Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:42 pm -
1 stop5h 03m
Wed 10/79:22 am -
2 stops7h 35m
Deal found 8/30![American Airlines logo]()
$465
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:36 pm -
2 stops6h 24m
Sat 10/36:00 am -
1 stop6h 43m
Deal found 8/29![United Airlines logo]()
$376
Last-minute flights from Maine to South CarolinaDiscover last-minute flight deals from Maine to South Carolina. Data last updated August 30, 2026 and is based on user searches.
Discover last-minute flight deals from Maine to South Carolina. Data last updated August 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:32 am -
1 stop5h 07m
Sun 9/61:03 pm -
1 stop6h 00m
Deal found 8/25![American Airlines logo]()
$247
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:45 am -
1 stop4h 03m
Wed 9/96:10 pm -
1 stop7h 00m
Deal found 8/26![United Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:37 pm -
1 stop7h 03m
Mon 9/217:51 pm -
1 stop4h 08m
Deal found 8/25![United Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:30 am -
1 stop5h 20m
Sat 9/195:45 am -
2 stops7h 02m
Deal found 8/25![United Airlines logo]()
$264
This deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:00 am -
Nonstop2h 31m
Fri 9/183:04 pm -
Nonstop2h 56m
Deal found 8/27![JetBlue logo]()
$270
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:50 am -
Nonstop2h 30m
Tue 9/223:15 pm -
Nonstop2h 32m
Deal found 8/27![Delta logo]()
$263
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop4h 38m
Thu 9/246:00 am -
1 stop4h 11m
Deal found 8/25![American Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am -
1 stop5h 42m
Sat 10/36:09 pm -
1 stop7h 08m
Deal found 8/27![Delta logo]()
$261
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:38 am -
2 stops9h 19m
Sat 10/35:38 pm -
1 stop5h 47m
Deal found 8/27![United Airlines logo]()
$266
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:00 pm -
1 stop4h 59m
Mon 10/56:00 am -
2 stops6h 43m
Deal found 8/29![United Airlines logo]()
$266
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:15 pm -
1 stop5h 25m
Sat 10/36:25 am -
1 stop6h 18m
Deal found 8/28![United Airlines logo]()
$263
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am -
1 stop5h 38m
Mon 10/55:59 pm -
1 stop4h 27m
Deal found 8/25![Delta logo]()
$253
One-way flights from Maine to South CarolinaSearch for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
Search for one-way flight options from Maine to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:45 pm -
1 stop8h 49m
Deal found 8/28![United Airlines logo]()
$110
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:20 am -
2 stops10h 30m
Deal found 8/28![Southwest logo]()
$115
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:15 am -
1 stop4h 44m
Deal found 8/26![Delta logo]()
$127
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:05 am -
2 stops9h 25m
Deal found 8/26![Southwest logo]()
$132
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:15 pm -
1 stop6h 10m
Deal found 8/25![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:34 pm -
1 stop8h 25m
Deal found 8/29![Multiple Airlines logo]()
$140
This Super.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:59 pm -
Nonstop2h 43m
Deal found 8/29![JetBlue logo]()
$141
This Cheapflightsfares deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:29 pm -
Nonstop2h 49m
Deal found 8/27![JetBlue logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:29 am -
1 stop10h 30m
Deal found 8/25![Multiple Airlines logo]()
$143
This JetBlue deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:00 pm -
Nonstop2h 47m
Deal found 8/26![JetBlue logo]()
$144
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
2 stops9h 24m
Deal found 8/27![United Airlines logo]()
$145
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:01 am -
1 stop7h 03m
Deal found 8/25![United Airlines logo]()
$145
Find flight deals from Maine to South Carolina
Keep the following information in mind while searching for Maine to South Carolina flight deals. Data was last updated August 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $209 (Delta) |
One-way from | $110 (United Airlines) |
Popular in | December |
Cheapest in | January |
Average price | $380 |
Good round-trip deal | $141 or less |
Good one-way deal | $125 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 30, 2026.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BostonSavannah
BOS Boston Logan Intl - SAV Savannah/Hilton Head
BOSSAV
Boston Logan Intl
Sat 11/7
5:30 am-11:38 am
1 stop6h 08m
Savannah/Hilton Head
Wed 11/11
6:00 am-12:25 pm
1 stop6h 25m
$219
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Sat 10/24
6:50 am-12:39 pm
1 stop5h 49m
Greenville
Mon 10/26
7:14 pm-1:20 am
1 stop6h 06m
$253
BostonColumbia
BOS Boston Logan Intl - CAE Columbia Metropolitan
BOSCAE
Boston Logan Intl
Sat 10/24
7:38 am-4:57 pm
2 stops9h 19m
Columbia Metropolitan
Sat 10/31
7:54 pm-11:59 pm
1 stop4h 05m
$266
BostonSavannah
BOS Boston Logan Intl - SAV Savannah/Hilton Head
BOSSAV
Boston Logan Intl
Wed 11/4
11:50 am-2:42 pm
Nonstop2h 52m
Savannah/Hilton Head
Wed 11/11
6:00 am-11:25 am
1 stop5h 25m
$269
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Thu 10/22
5:39 am-10:18 am
1 stop4h 39m
Greenville
Fri 10/23
3:39 pm-10:08 pm
1 stop6h 29m
$289
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Thu 11/12
7:00 am-2:18 pm
1 stop7h 18m
Charleston
Tue 11/17
2:46 pm-5:09 pm
Nonstop2h 23m
$293
BostonSavannah
BOS Boston Logan Intl - SAV Savannah/Hilton Head
BOSSAV
Boston Logan Intl
Wed 10/21
7:38 am-2:16 pm
1 stop6h 38m
Savannah/Hilton Head
Wed 10/28
11:19 am-3:50 pm
1 stop4h 31m
$297
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Sat 11/7
11:10 am-1:44 pm
Nonstop2h 34m
Charleston
Wed 11/11
3:15 pm-9:28 pm
1 stop6h 13m
$299
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Wed 11/11
3:00 pm-9:22 pm
1 stop6h 22m
Charleston
Sat 11/14
11:31 am-1:55 pm
Nonstop2h 24m
$299
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Thu 9/17
7:00 am-11:19 am
1 stop4h 19m
Myrtle Beach Intl
Sun 9/20
5:55 pm-10:19 pm
1 stop4h 24m
$304
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Maine to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Maine with our price prediction graph.
BOS-SAV
BOS-CAE
PWM-MYR
BOS-HHH
BOS-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Maine to South Carolina
USME-USSC
BOS-SAV
BOS-CAE
PWM-MYR
BOS-HHH
What is the cheapest month to book a flight from Maine to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Maine to South Carolina (average of $266). Flying from Maine to South Carolina in March is currently the most expensive (average of $421). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ME to SC?
Find hourly flight availability from Maine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 30, 2026.
It’s optimal to fly from Maine to South Carolina in the morning. By choosing this option you can save up to 43% on the cost of your flight, compared to a flight at noon.
How much does it cost to fly round-trip from Maine to South Carolina?
Airfare is below average for this route at the moment.
Maine to South Carolina flights typically cost between $254 and $555 in November.The cheapest round-trip price found within the last 5 days was $158 on Breeze Airways (Nov 2-Nov 6).
How far ahead should I book a flight from Maine to South Carolina?
The price you pay for your flight from Maine to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 48 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 30, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Maine to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Entertainment
6.7
Food
6.7
Overall
8.2
Comfort
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.7
Food
6.7
Overall
8.2
Comfort
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.7
Food
6.7
Overall
8.2
Comfort
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.7
Food
6.7
Overall
8.2
Comfort
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.7
Food
6.7
Overall
8.2
Comfort
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.7
Food
6.7
Overall
8.2
Comfort
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Maine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Maine to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Maine to South Carolina by cabin class
Find flights from Maine to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Maine and South Carolina flights
Browse other Maine and South Carolina flight options. Last updated on August 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Maine after your stay in South Carolina
Maine to South Carolina flights
Consider these flights traveling from Maine to South Carolina.
Top 5 airlines flying from Maine to South Carolina
Discover the top 5 airlines that operate flights from Maine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$106 | Average$260 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$138 | Average$378 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$401 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$223 | Average$417 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$449 | FlexibilityNo cancel fee | On-time63% |