$146+ Cheap flights from Portland, ME to Greenville (PWM - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — GSP
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Greenville
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Cheapest flights from Portland to GreenvilleExplore the most affordable flight options available from Portland to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Portland to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:35 am -
1 stop4h 14m
Tue 10/135:59 pm -
1 stop3h 43m
Deal found 9/8![Breeze Airways logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am -
1 stop4h 31m
Fri 9/257:10 pm -
1 stop4h 14m
Deal found 9/8![Breeze Airways logo]()
$270
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:27 pm -
1 stop6h 12m
Sat 10/2411:59 am -
1 stop4h 48m
Deal found 9/10![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:10 pm -
1 stop4h 14m
Mon 11/168:32 pm -
2 stops19h 52m
Deal found 9/13![Multiple Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:09 pm -
2 stops16h 23m
Mon 10/57:20 pm -
1 stop4h 14m
Deal found 9/11![Breeze Airways logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:10 pm -
1 stop4h 14m
Mon 11/308:32 pm -
2 stops39h 16m
Deal found 9/12![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:05 pm -
1 stop4h 14m
Tue 10/65:59 pm -
1 stop3h 43m
Deal found 9/11![Breeze Airways logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:10 pm -
1 stop4h 14m
Sun 11/1510:42 am -
1 stop3h 43m
Deal found 9/13![Breeze Airways logo]()
$380
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:06 pm -
1 stop4h 03m
Mon 10/56:02 pm -
1 stop4h 34m
Deal found 9/11![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:30 am -
1 stop5h 10m
Sat 10/173:58 pm -
1 stop6h 38m
Deal found 9/9![American Airlines logo]()
$398
Best flights from Portland to GreenvilleDiscover carefully curated flight deals from Portland to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Portland to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:50 am -
1 stop4h 26m
Sat 10/32:16 pm -
1 stop7h 30m
Deal found 9/9![United Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:10 pm -
1 stop4h 14m
Sun 10/253:18 pm -
1 stop17h 50m
Deal found 9/8![Multiple Airlines logo]()
$445
This Breeze Airways deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:10 pm -
1 stop4h 14m
Sun 10/2510:42 am -
1 stop3h 43m
Deal found 9/12![Breeze Airways logo]()
$466
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:40 pm -
1 stop7h 20m
Fri 10/306:20 am -
1 stop7h 56m
Deal found 9/10![United Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:41 pm -
1 stop7h 32m
Sat 10/246:20 am -
2 stops8h 18m
Deal found 9/10![United Airlines logo]()
$487
Last-minute flights from Portland to GreenvilleDiscover last-minute flight deals from Portland to Greenville. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Greenville. Data last updated September 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am -
1 stop4h 31m
Fri 9/257:10 pm -
1 stop4h 14m
Deal found 9/8![Breeze Airways logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:35 am -
1 stop4h 14m
Sat 10/38:24 pm -
2 stops17h 56m
Deal found 9/9![Breeze Airways logo]()
$405
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:50 am -
1 stop4h 26m
Sat 10/32:16 pm -
1 stop7h 30m
Deal found 9/9![United Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:09 pm -
2 stops16h 23m
Mon 10/57:20 pm -
1 stop4h 14m
Deal found 9/11![Breeze Airways logo]()
$350
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:06 pm -
1 stop4h 03m
Mon 10/56:02 pm -
1 stop4h 34m
Deal found 9/11![American Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:05 pm -
1 stop4h 14m
Tue 10/65:59 pm -
1 stop3h 43m
Deal found 9/11![Breeze Airways logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:35 am -
1 stop4h 14m
Tue 10/135:59 pm -
1 stop3h 43m
Deal found 9/8![Breeze Airways logo]()
$226
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:30 am -
1 stop5h 10m
Sat 10/173:58 pm -
1 stop6h 38m
Deal found 9/9![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:27 pm -
1 stop6h 12m
Sat 10/2411:59 am -
1 stop4h 48m
Deal found 9/10![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:40 pm -
1 stop7h 20m
Fri 10/306:20 am -
1 stop7h 56m
Deal found 9/10![United Airlines logo]()
$420
One-way flights from Portland to GreenvilleSearch for one-way flight options from Portland to Greenville. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
Search for one-way flight options from Portland to Greenville. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:48 am -
1 stop5h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Breeze Airways logo]()
$146
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:53 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$163
This Breeze Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am -
1 stop4h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Breeze Airways logo]()
$164
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:28 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop4h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Breeze Airways logo]()
$185
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:32 pm -
1 stop4h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:10 am -
1 stop4h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![American Airlines logo]()
$196
This Breeze Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:35 am -
1 stop4h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Breeze Airways logo]()
$198
Find flight deals from Portland to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $226 (Kiwi.com) |
One-way from | $146 (Breeze Airways) |
Popular in | April |
Cheapest in | August |
Average price | $474 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Portland to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 12/8
4:53 pm-9:49 pm
1 stop4h 56m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
Quickest round-trip
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 10/13
7:35 am-11:49 am
1 stop4h 14m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 12/8
6:00 am-4:56 pm
2 stops10h 56m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Sun 10/11
6:00 am-10:45 am
1 stop4h 45m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$225
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Sun 10/4
6:00 am-10:45 am
1 stop4h 45m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Thu 10/1
3:05 pm-7:19 pm
1 stop4h 14m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$236
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Sat 10/10
5:30 am-10:40 am
1 stop5h 10m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$239
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Thu 10/1
6:00 am-2:16 pm
2 stops8h 16m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$263
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 9/29
9:50 am-2:16 pm
1 stop4h 26m
Greenville
Sat 10/3
2:16 pm-9:46 pm
1 stop7h 30m
$411
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Wed 10/28
3:40 pm-11:00 pm
1 stop7h 20m
Greenville
Fri 10/30
6:20 am-2:16 pm
1 stop7h 56m
$420
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Portland to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Greenville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland, Maine-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Portland with our price prediction graph.
PWM-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 13, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Portland to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Portland to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Portland and Greenville flights
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Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Portland to Greenville
Discover the top 3 airlines that operate flights from Portland to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$124 | Average$456 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$386 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$351 | Average$466 | FlexibilityNo cancel fee | On-time71% |