In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from PWM to FLO?

When flying from Portland, Maine to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Portland to Florence that include hotel bookings?

Yes. In addition to deals on Portland to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Florence.

Can I find deals for business class flights from Portland to Florence?

Yes. Cheapflights offers flight deals from Portland to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$484+ Flights from Portland, ME to Florence, SC

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Cheap flight deals from Portland to Florence

Round-trip from	$484 (American Airlines)

From Portland to Florence

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Cheapest flights from Portland to Florence
Explore the most affordable flight options available from Portland to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.

Fri 8/16:01 pmPWM - FLO

1 stop5h 58mAmerican Airlines

Tue 8/55:07 amFLO - PWM

2 stops7h 25mAmerican Airlines

Deal found 7/17

$484

Best flights from Portland to Florence
Discover carefully curated flight deals from Portland to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2025.

Fri 8/16:01 pmPWM - FLO

1 stop5h 58mAmerican Airlines

Tue 8/55:07 amFLO - PWM

2 stops7h 25mAmerican Airlines

Deal found 7/17

$484

Last-minute flights from Portland to Florence
Discover last-minute flight deals from Portland to Florence. Data last updated July 18, 2025 and is based on user searches.

Fri 8/16:01 pmPWM - FLO

1 stop5h 58mAmerican Airlines

Tue 8/55:07 amFLO - PWM

2 stops7h 25mAmerican Airlines

Deal found 7/17

$484

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to Florence that are best for you.

Fly from

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Route

Depart

Return

Price

PortlandFlorence

PWM - FLO

PWMFLO

Portland

Fri 8/1

6:01 pm-11:59 pm

1 stop5h 58m

Florence

Tue 8/5

5:07 am-12:32 pm

2 stops7h 25m

$484

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Deals found on 7/17

Best time to book a flight from Portland to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Florence

What is the cheapest month to book a flight from Portland, Maine to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Florence, South Carolina (average of $366). Flying from Portland, Maine to Florence, South Carolina in October is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Read through reviews of airlines operating flights from Portland to Florence, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Andrew,May 2025

LAX - MIA

Related info for your journey

Can I find deals for flights from Portland to Florence that include hotel bookings?
Yes. In addition to deals on Portland to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Florence.
Can I find deals for business class flights from Portland to Florence?
Yes. Cheapflights offers flight deals from Portland to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Portland, Maine to Florence, South Carolina?
Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Florence, South Carolina (average of $366). Flying from Portland, Maine to Florence, South Carolina in October is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$484+ Cheap flights from Portland, ME to Florence, SC (PWM - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Portland to Florence

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Find flight deals from Portland to Florence

Cheapest flights from Portland to FlorenceExplore the most affordable flight options available from Portland to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.

Explore the most affordable flight options available from Portland to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to Florence that are best for you.

Best time to book a flight from Portland to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to Florence

What is the cheapest month to book a flight from Portland, Maine to Florence, South Carolina?

Reviews of airlines servicing Florence

Read through reviews of airlines operating flights from Portland to Florence, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Portland to Florence that include hotel bookings?

How can I find direct flights from Portland to Florence?

Can I find deals for business class flights from Portland to Florence?

What is the cheapest month to book a flight from Portland, Maine to Florence, South Carolina?

Traveling to a place near Florence?

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Cheapest flights from Portland to Florence
Explore the most affordable flight options available from Portland to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.