$58+ Cheap flights from Portland, ME (PWM) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Jul 21 — Jul 281
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to South Carolina
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Wed 9/302:09 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/19![Breeze Airways logo]()
$122
This Breeze Airways deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/16![Breeze Airways logo]()
$138
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:40 pm
PWM
- CHS
1 stop4h 39m
Multiple Airlines
Wed 9/302:09 pm
CHS
- PWM
Nonstop2h 25m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$149
This Expedia deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:00 am
PWM
- SAV
1 stop4h 39m
Multiple Airlines
Fri 7/107:27 pm
SAV
- PWM
1 stop4h 49m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Thu 8/276:25 pm
MYR
- PWM
1 stop4h 14m
Breeze Airways
Deal found 6/17![Breeze Airways logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 7/76:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/18![Breeze Airways logo]()
$202
This Breeze Airways deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:30 pm
PWM
- CHS
Nonstop2h 43m
Breeze Airways
Mon 10/262:25 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/16![Breeze Airways logo]()
$203
This Priceline deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Sun 8/236:25 pm
MYR
- PWM
1 stop4h 14m
Breeze Airways
Deal found 6/20![Breeze Airways logo]()
$210
This JetBlue deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:17 pm
PWM
- SAV
1 stop5h 03m
JetBlue
Sat 8/297:16 pm
SAV
- PWM
1 stop4h 58m
JetBlue
Deal found 6/16![JetBlue logo]()
$217
This Breeze Airways deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm
PWM
- CHS
Nonstop2h 43m
Breeze Airways
Mon 10/122:25 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/20![Breeze Airways logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Sun 8/306:25 pm
MYR
- PWM
1 stop4h 14m
Breeze Airways
Deal found 6/17![Breeze Airways logo]()
$235
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:17 pm
PWM
- SAV
1 stop5h 03m
Multiple Airlines
Sat 8/296:35 pm
SAV
- PWM
1 stop4h 20m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$256
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/19![Breeze Airways logo]()
$138
This JetBlue deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:17 pm
PWM
- SAV
1 stop5h 03m
JetBlue
Sat 8/297:16 pm
SAV
- PWM
1 stop4h 58m
JetBlue
Deal found 6/17![JetBlue logo]()
$257
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:45 am
PWM
- SAV
2 stops11h 55m
Southwest
Sat 8/298:15 am
SAV
- PWM
1 stop6h 45m
Southwest
Deal found 6/19![Southwest logo]()
$290
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:00 am
PWM
- SAV
1 stop6h 55m
Delta
Mon 12/141:00 pm
SAV
- PWM
1 stop6h 29m
Delta
Deal found 6/18![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:30 am
PWM
- SAV
1 stop5h 07m
United Airlines
Wed 11/47:00 pm
SAV
- PWM
1 stop4h 59m
United Airlines
Deal found 6/16![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:02 am
PWM
- HHH
1 stop7h 17m
American Airlines
Wed 11/182:51 pm
HHH
- PWM
2 stops8h 47m
American Airlines
Deal found 6/20![American Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:00 am
PWM
- MYR
1 stop8h 12m
Multiple Airlines
Mon 7/203:31 pm
MYR
- PWM
2 stops29h 48m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$431
This Breeze Airways deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm
PWM
- CHS
Nonstop2h 43m
Breeze Airways
Mon 10/122:25 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/19![Breeze Airways logo]()
$223
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:30 am
PWM
- SAV
1 stop8h 15m
Southwest
Tue 10/2711:35 am
SAV
- PWM
2 stops10h 55m
Southwest
Deal found 6/19![Southwest logo]()
$296
This Breeze Airways deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am
PWM
- SAV
1 stop4h 43m
Breeze Airways
Wed 10/144:55 pm
SAV
- PWM
1 stop4h 24m
Breeze Airways
Deal found 6/17![Breeze Airways logo]()
$277
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:59 pm
PWM
- MYR
1 stop4h 56m
Delta
Tue 7/214:16 pm
MYR
- PWM
1 stop6h 58m
Delta
Deal found 6/16![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:10 am
PWM
- SAV
2 stops10h 40m
Southwest
Mon 12/148:00 am
SAV
- PWM
1 stop6h 50m
Southwest
Deal found 6/18![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am
PWM
- SAV
1 stop9h 04m
United Airlines
Sat 8/2912:59 pm
SAV
- PWM
1 stop8h 24m
United Airlines
Deal found 6/20![United Airlines logo]()
$351
This Breeze Airways deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:05 pm
PWM
- CHS
1 stop5h 54m
Breeze Airways
Wed 9/302:09 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/18![Breeze Airways logo]()
$296
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:05 am
PWM
- MYR
1 stop4h 42m
Delta
Sat 9/126:00 am
MYR
- PWM
2 stops7h 54m
Delta
Deal found 6/17![Delta logo]()
$360
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:40 am
PWM
- MYR
2 stops10h 45m
Southwest
Mon 8/316:15 pm
MYR
- PWM
1 stop4h 10m
Southwest
Deal found 6/19![Southwest logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Sun 8/239:07 pm
MYR
- PWM
2 stops20h 42m
Breeze Airways
Deal found 6/20![Breeze Airways logo]()
$313
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:03 am
PWM
- CHS
1 stop7h 55m
United Airlines
Tue 9/16:30 am
CHS
- PWM
1 stop8h 04m
United Airlines
Deal found 6/19![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:38 am
PWM
- CAE
2 stops8h 27m
American Airlines
Thu 7/96:01 am
CAE
- PWM
1 stop6h 34m
American Airlines
Deal found 6/20![American Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:12 pm
PWM
- MYR
2 stops10h 18m
Delta
Thu 8/132:18 pm
MYR
- PWM
2 stops10h 41m
Delta
Deal found 6/20![Delta logo]()
$378
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:10 am
PWM
- SAV
2 stops7h 40m
Southwest
Wed 11/48:00 am
SAV
- PWM
1 stop6h 50m
Southwest
Deal found 6/16![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:43 pm
PWM
- GSP
1 stop7h 54m
United Airlines
Wed 11/186:30 am
GSP
- PWM
1 stop7h 50m
United Airlines
Deal found 6/20![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:16 am
PWM
- HHH
1 stop5h 04m
American Airlines
Mon 8/34:55 pm
HHH
- PWM
1 stop5h 41m
American Airlines
Deal found 6/17![American Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:35 pm
PWM
- GSP
1 stop6h 39m
Delta
Sun 10/255:40 am
GSP
- PWM
1 stop6h 38m
Delta
Deal found 6/19![Delta logo]()
$381
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:40 am
PWM
- CLT
1 stop4h 20m
Southwest
Tue 10/611:45 am
CLT
- PWM
1 stop4h 20m
Southwest
Deal found 6/20![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:15 am
PWM
- CAE
1 stop4h 41m
United Airlines
Wed 7/87:45 pm
CAE
- PWM
1 stop4h 06m
United Airlines
Deal found 6/19![United Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:16 am
PWM
- AGS
1 stop5h 03m
American Airlines
Sun 7/126:00 am
AGS
- PWM
1 stop4h 05m
American Airlines
Deal found 6/16![American Airlines logo]()
$487
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:30 am
PWM
- CHS
2 stops9h 05m
Southwest
Tue 10/2010:50 am
CHS
- PWM
2 stops10h 40m
Southwest
Deal found 6/16![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
PWM
- CLT
1 stop4h 39m
Delta
Tue 7/710:01 am
CLT
- PWM
1 stop4h 18m
Delta
Deal found 6/17![Delta logo]()
$406
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:15 am
PWM
- CAE
1 stop4h 32m
United Airlines
Wed 9/21:48 pm
CAE
- PWM
2 stops10h 11m
United Airlines
Deal found 6/19![United Airlines logo]()
$416
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated June 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:58 pm
PWM
- CAE
1 stop6h 01m
American Airlines
Thu 7/96:01 am
CAE
- PWM
1 stop6h 34m
American Airlines
Deal found 6/17![American Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 7/76:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/18![Breeze Airways logo]()
$202
This Expedia deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:00 am
PWM
- SAV
1 stop4h 39m
Multiple Airlines
Fri 7/107:27 pm
SAV
- PWM
1 stop4h 49m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$200
This Breeze Airways deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Sat 7/114:33 pm
CHS
- PWM
1 stop6h 22m
Breeze Airways
Deal found 6/18![Breeze Airways logo]()
$236
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:59 pm
PWM
- MYR
1 stop4h 56m
Delta
Tue 7/214:16 pm
MYR
- PWM
1 stop6h 58m
Delta
Deal found 6/16![Delta logo]()
$317
This Priceline deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Thu 7/236:25 pm
MYR
- PWM
1 stop4h 14m
Breeze Airways
Deal found 6/18![Breeze Airways logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:11 pm
PWM
- CHS
1 stop4h 20m
Breeze Airways
Sat 7/184:33 pm
CHS
- PWM
1 stop6h 22m
Breeze Airways
Deal found 6/20![Breeze Airways logo]()
$331
This CheapOair deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:40 pm
PWM
- CHS
1 stop5h 12m
JetBlue
Fri 7/2410:58 am
CHS
- PWM
1 stop26h 47m
JetBlue
Deal found 6/19![JetBlue logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Fri 7/243:24 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 6/17![Breeze Airways logo]()
$323
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
PWM
- SAV
1 stop4h 54m
Delta
Tue 8/45:52 pm
SAV
- PWM
1 stop7h 07m
Delta
Deal found 6/19![Delta logo]()
$271
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:20 pm
PWM
- SAV
2 stops9h 32m
United Airlines
Tue 8/47:15 pm
SAV
- PWM
1 stop4h 36m
United Airlines
Deal found 6/19![United Airlines logo]()
$276
This CheapOair deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:40 pm
PWM
- CHS
1 stop4h 39m
JetBlue
Sun 8/28:14 pm
CHS
- PWM
1 stop16h 16m
JetBlue
Deal found 6/20![JetBlue logo]()
$329
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:19 pm
PWM
- CHS
Nonstop2h 43m
Breeze Airways
Deal found 6/19![Breeze Airways logo]()
$58
This Breeze Airways deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/19![Breeze Airways logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/16![Breeze Airways logo]()
$113
This Breeze Airways deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/20![Breeze Airways logo]()
$114
This Breeze Airways deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:30 pm
PWM
- CHS
Nonstop2h 43m
Breeze Airways
Deal found 6/19![Breeze Airways logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:00 am
PWM
- SAV
1 stop14h 31m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$135
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:50 am
PWM
- SAV
1 stop4h 20m
Southwest
Deal found 6/20![Southwest logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CLT
2 stops30h 20m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$138
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:40 pm
PWM
- CHS
1 stop4h 39m
JetBlue
Deal found 6/18![JetBlue logo]()
$138
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 am
PWM
- SAV
2 stops9h 01m
United Airlines
Deal found 6/20![United Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:00 am
PWM
- GSP
1 stop4h 26m
Breeze Airways
Deal found 6/20![Breeze Airways logo]()
$143
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:45 pm
PWM
- SAV
1 stop4h 50m
Southwest
Deal found 6/19![Southwest logo]()
$144
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated June 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $122 (Priceline) |
One-way from | $58 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $416 |
Good round-trip deal | $184 or less |
Good one-way deal | $112 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Tue 8/18
8:00 am-10:35 am
Nonstop2h 35m
Charleston
Tue 8/25
6:54 pm-9:19 pm
Nonstop2h 25m
$138
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Wed 10/7
5:19 pm-8:02 pm
Nonstop2h 43m
Charleston
Mon 10/12
2:25 pm-4:50 pm
Nonstop2h 25m
$223
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Tue 8/25
1:17 pm-6:20 pm
1 stop5h 03m
Savannah/Hilton Head
Sat 8/29
7:16 pm-12:14 am
1 stop4h 58m
$257
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Sat 10/3
7:00 am-11:43 am
1 stop4h 43m
Savannah/Hilton Head
Wed 10/14
4:55 pm-9:19 pm
1 stop4h 24m
$277
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Tue 8/25
5:45 am-5:40 pm
2 stops11h 55m
Savannah/Hilton Head
Sat 8/29
8:15 am-3:00 pm
1 stop6h 45m
$290
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Thu 10/22
10:30 am-6:45 pm
1 stop8h 15m
Savannah/Hilton Head
Tue 10/27
11:35 am-10:30 pm
2 stops10h 55m
$296
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Sun 9/27
3:05 pm-8:59 pm
1 stop5h 54m
Charleston
Wed 9/30
2:09 pm-4:34 pm
Nonstop2h 25m
$296
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Thu 12/10
10:00 am-4:55 pm
1 stop6h 55m
Savannah/Hilton Head
Mon 12/14
1:00 pm-7:29 pm
1 stop6h 29m
$299
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Thu 12/10
5:10 am-3:50 pm
2 stops10h 40m
Savannah/Hilton Head
Mon 12/14
8:00 am-2:50 pm
1 stop6h 50m
$304
PortlandMyrtle Beach
PWM - MYR
PWMMYR
Portland
Thu 8/20
7:00 am-11:21 am
1 stop4h 21m
Myrtle Beach Intl
Sun 8/23
9:07 pm-5:49 pm
2 stops20h 42m
$313
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PWM-CHS
PWM-SAV
PWM-CLT
PWM-GSP
PWM-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PWM-USSC
PWM-CHS
PWM-SAV
PWM-CLT
PWM-GSP
What is the cheapest month to book a flight from Portland, Maine to South Carolina?
Currently, June is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $73). Flying from Portland, Maine to South Carolina in April is currently the most expensive (average of $148). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PWM to SC?
Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 21, 2026.
One of the essential ways to save on airfare from Portland, Maine to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 46% on airfare.
How much does it cost to fly round-trip from Portland, Maine to South Carolina?
How far ahead should I book a flight from Portland, Maine to South Carolina?
The price you pay for your flight from Portland, Maine to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 30 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 21, 2026.
Read reviews from past customers who have flown Breeze Airways,Southwest, andDelta from Portland to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.4
Crew
8.8
Entertainment
6.7
Food
6.7
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Crew
8.8
Entertainment
6.7
Food
6.7
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Crew
8.8
Entertainment
6.7
Food
6.7
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Crew
8.8
Entertainment
6.7
Food
6.7
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Crew
8.8
Entertainment
6.7
Food
6.7
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Crew
8.8
Entertainment
6.7
Food
6.7
Comfort
8.2
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on June 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$103 | Average$253 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$118 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$439 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$277 | Average$409 | FlexibilityNo cancel fee | On-time69% |