$83+ Cheap flights from Portland, ME (PWM) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:35 pm -
Nonstop2h 43m
Fri 11/132:30 pm -
Nonstop2h 25m
Deal found 9/20![Breeze Airways logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 pm -
Nonstop2h 43m
Fri 11/62:30 pm -
Nonstop2h 25m
Deal found 9/20![Breeze Airways logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:35 pm -
Nonstop2h 43m
Fri 12/252:30 pm -
Nonstop2h 25m
Deal found 9/23![Breeze Airways logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:35 pm -
Nonstop2h 43m
Mon 12/142:30 pm -
Nonstop2h 25m
Deal found 9/23![Breeze Airways logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:35 pm -
Nonstop2h 43m
Fri 11/132:30 pm -
Nonstop2h 25m
Deal found 9/19![Breeze Airways logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:35 pm -
Nonstop2h 43m
Fri 12/252:30 pm -
Nonstop2h 25m
Deal found 9/23![Breeze Airways logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:35 pm -
Nonstop2h 43m
Mon 11/22:30 pm -
Nonstop2h 25m
Deal found 9/21![Breeze Airways logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:35 pm -
Nonstop2h 43m
Mon 12/212:30 pm -
Nonstop2h 25m
Deal found 9/23![Breeze Airways logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm -
Nonstop2h 43m
Wed 10/142:09 pm -
Nonstop2h 25m
Deal found 9/22![Breeze Airways logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:35 pm -
Nonstop2h 43m
Wed 11/117:00 am -
1 stop26h 21m
Deal found 9/20![Breeze Airways logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:35 pm -
Nonstop2h 43m
Mon 11/92:30 pm -
Nonstop2h 25m
Deal found 9/19![Breeze Airways logo]()
$217
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:50 am -
1 stop4h 31m
Tue 11/105:54 pm -
1 stop5h 27m
Deal found 9/23![United Airlines logo]()
$320
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop5h 52m
Sat 11/215:49 pm -
1 stop5h 42m
Deal found 9/21![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:35 am -
1 stop4h 46m
Tue 11/175:54 pm -
1 stop5h 27m
Deal found 9/19![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:00 am -
1 stop5h 02m
Sun 1/314:25 pm -
1 stop5h 11m
Deal found 9/19![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:35 am -
2 stops9h 15m
Mon 1/116:45 am -
2 stops14h 55m
Deal found 9/19![Southwest logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
2 stops31h 38m
Mon 10/262:30 pm -
Nonstop2h 25m
Deal found 9/19![Multiple Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:27 am -
1 stop7h 51m
Sat 11/148:00 am -
1 stop5h 08m
Deal found 9/20![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:50 am -
1 stop4h 31m
Tue 11/175:54 pm -
1 stop5h 27m
Deal found 9/19![United Airlines logo]()
$320
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:50 am -
2 stops12h 14m
Wed 11/187:04 pm -
1 stop4h 17m
Deal found 9/22![United Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:05 pm -
1 stop6h 55m
Mon 11/28:50 pm -
2 stops13h 00m
Deal found 9/23![Southwest logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/97:10 am -
1 stop7h 12m
Tue 3/236:22 pm -
1 stop4h 28m
Deal found 9/23![American Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:18 pm -
1 stop4h 25m
Wed 12/25:00 pm -
1 stop6h 20m
Deal found 9/22![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:20 am -
1 stop4h 25m
Sun 11/17:35 pm -
1 stop4h 15m
Deal found 9/22![Southwest logo]()
$371
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:55 pm -
1 stop5h 04m
Mon 10/197:53 pm -
1 stop4h 06m
Deal found 9/20![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 am -
1 stop5h 14m
Mon 10/264:10 pm -
1 stop6h 26m
Deal found 9/20![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
1 stop5h 50m
Sun 12/135:22 pm -
1 stop6h 59m
Deal found 9/23![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:50 am -
1 stop4h 31m
Mon 11/95:54 pm -
1 stop5h 27m
Deal found 9/21![United Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:40 pm -
2 stops10h 55m
Thu 11/125:30 am -
2 stops18h 25m
Deal found 9/20![Southwest logo]()
$392
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop6h 59m
Sun 12/134:18 pm -
1 stop7h 34m
Deal found 9/23![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:45 am -
1 stop4h 49m
Fri 11/65:54 pm -
1 stop4h 39m
Deal found 9/21![American Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop4h 45m
Tue 10/272:19 pm -
2 stops9h 02m
Deal found 9/22![United Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:35 am -
2 stops9h 15m
Mon 1/116:45 am -
2 stops14h 55m
Deal found 9/23![Southwest logo]()
$399
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:28 am -
1 stop5h 15m
Thu 11/54:13 pm -
1 stop7h 05m
Deal found 9/21![Delta logo]()
$371
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:50 am -
1 stop4h 31m
Thu 11/125:54 pm -
1 stop5h 27m
Deal found 9/20![United Airlines logo]()
$366
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:40 pm -
2 stops10h 55m
Fri 11/67:55 pm -
1 stop4h 00m
Deal found 9/21![Southwest logo]()
$406
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:01 am -
1 stop4h 59m
Sat 10/173:35 pm -
1 stop5h 26m
Deal found 9/21![Delta logo]()
$381
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:45 pm -
1 stop5h 40m
Mon 11/910:45 am -
2 stops13h 10m
Deal found 9/21![Southwest logo]()
$425
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:01 am -
1 stop4h 59m
Fri 10/165:59 pm -
1 stop5h 19m
Deal found 9/21![Delta logo]()
$406
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:21 pm -
1 stop6h 37m
Sat 1/26:01 am -
1 stop4h 39m
Deal found 9/20![American Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:15 am -
1 stop4h 29m
Wed 10/285:54 pm -
1 stop5h 27m
Deal found 9/23![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:10 pm -
1 stop4h 35m
Sun 11/158:50 pm -
2 stops13h 00m
Deal found 9/23![Southwest logo]()
$428
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated September 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm -
Nonstop2h 43m
Wed 10/142:09 pm -
Nonstop2h 25m
Deal found 9/22![Breeze Airways logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm -
Nonstop2h 43m
Tue 10/133:00 pm -
1 stop18h 08m
Deal found 9/22![Breeze Airways logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:19 pm -
Nonstop2h 43m
Sat 10/107:00 am -
1 stop26h 21m
Deal found 9/22![Breeze Airways logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:19 pm -
Nonstop2h 43m
Mon 10/192:30 pm -
Nonstop2h 25m
Deal found 9/20![Breeze Airways logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
1 stop16h 17m
Tue 10/203:18 pm -
1 stop17h 50m
Deal found 9/22![Breeze Airways logo]()
$292
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop5h 25m
Tue 10/2711:55 am -
1 stop3h 48m
Deal found 9/20![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:41 pm -
1 stop7h 32m
Tue 10/276:20 am -
1 stop7h 56m
Deal found 9/21![United Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 am -
1 stop4h 31m
Tue 11/35:54 pm -
1 stop5h 27m
Deal found 9/22![United Airlines logo]()
$320
This Breeze Airways deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:10 pm -
1 stop5h 49m
Mon 11/22:30 pm -
Nonstop2h 25m
Deal found 9/23![Breeze Airways logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:35 pm -
Nonstop2h 43m
Mon 11/22:30 pm -
Nonstop2h 25m
Deal found 9/21![Breeze Airways logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:09 pm -
2 stops16h 29m
Fri 11/62:30 pm -
Nonstop2h 25m
Deal found 9/20![Breeze Airways logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:09 pm -
2 stops16h 29m
Mon 11/22:30 pm -
Nonstop2h 25m
Deal found 9/20![Breeze Airways logo]()
$263
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/195:00 pm -
Nonstop2h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Breeze Airways logo]()
$83
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:50 am -
1 stop4h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![United Airlines logo]()
$158
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:50 am -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![United Airlines logo]()
$158
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop5h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$163
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:53 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Delta logo]()
$163
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:26 pm -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$170
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:40 am -
2 stops13h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Southwest logo]()
$174
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:15 am -
2 stops8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:00 am -
1 stop4h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Breeze Airways logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:35 am -
1 stop4h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Breeze Airways logo]()
$183
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1911:25 am -
1 stop5h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Delta logo]()
$183
This Breeze Airways deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:48 am -
1 stop5h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Breeze Airways logo]()
$184
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $117 (Kiwi.com) |
One-way from | $83 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $402 |
Good round-trip deal | $168 or less |
Good one-way deal | $89 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Mon 11/2
5:35 am-10:21 am
1 stop4h 46m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$158
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Sat 10/24
6:00 am-10:33 am
1 stop4h 33m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Sat 10/31
7:20 am-12:10 pm
1 stop4h 50m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 12/8
4:53 pm-9:49 pm
1 stop4h 56m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Tue 10/20
6:00 am-11:38 am
1 stop5h 38m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
PortlandGreenville
PWM Portland - GSP Greenville
PWMGSP
Portland
Tue 12/8
7:10 am-11:19 am
1 stop4h 09m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
PortlandCharleston
PWM Portland - CHS Charleston
PWMCHS
Portland
Sat 10/24
5:15 am-2:04 pm
2 stops8h 49m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Thu 11/26
12:45 pm-9:43 pm
2 stops8h 58m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Sat 10/24
5:15 am-3:16 pm
2 stops10h 01m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
PortlandMyrtle Beach
PWM Portland - MYR Myrtle Beach Intl
PWMMYR
Portland
Sat 10/31
9:46 am-5:11 pm
2 stops7h 25m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PWM-CHS
PWM-MYR
PWM-HHH
PWM-GSP
PWM-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PWM-USSC
PWM-CHS
PWM-MYR
PWM-HHH
PWM-GSP
What is the cheapest month to book a flight from Portland, Maine to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $255). Flying from Portland, Maine to South Carolina in April is currently the most expensive (average of $497). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PWM to SC?
Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 24, 2026.
One of the essential ways to save on airfare from Portland, Maine to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 43% on airfare.
How much does it cost to fly round-trip from Portland, Maine to South Carolina?
Airfare is below average for this route at the moment.
Portland, Maine to South Carolina flights typically cost between $228 and $556 in January.The cheapest round-trip price found within the last 5 days was $117 on Breeze Airways (Jan 8-Jan 11).
How far ahead should I book a flight from Portland, Maine to South Carolina?
The price you pay for your flight from Portland, Maine to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 48 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 24, 2026.
Read reviews from past customers who have flown Breeze Airways,Southwest, andDelta from Portland to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.7
Crew
8.8
Boarding
8.4
Comfort
8.2
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Crew
8.8
Boarding
8.4
Comfort
8.2
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Crew
8.8
Boarding
8.4
Comfort
8.2
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Crew
8.8
Boarding
8.4
Comfort
8.2
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Crew
8.8
Boarding
8.4
Comfort
8.2
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Crew
8.8
Boarding
8.4
Comfort
8.2
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
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Complete your trip
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Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on September 24, 2026.
Popular flight searches
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Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$111 | Average$275 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$124 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$401 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$258 | Average$437 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$453 | FlexibilityNo cancel fee | On-time63% |