$62+ Cheap flights from Portland, ME (PWM) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Jun 9 — Jun 161
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to South Carolina
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/256:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$116
This Booking.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 9/18:00 am
CHS
- PWM
1 stop7h 59m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$144
This Breeze Airways deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:00 am
PWM
- SAV
1 stop4h 43m
Breeze Airways
Sat 10/34:55 pm
SAV
- PWM
1 stop4h 24m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$191
This Breeze Airways deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Wed 5/203:20 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$193
This Gotogate deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Mon 6/153:08 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$208
This Booking.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Wed 7/294:33 pm
CHS
- PWM
1 stop4h 18m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$214
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:51 pm
PWM
- CHS
1 stop6h 20m
American Airlines
Wed 7/296:41 am
CHS
- PWM
1 stop5h 54m
American Airlines
Deal found 5/7![American Airlines logo]()
$219
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:30 pm
PWM
- CHS
Nonstop2h 35m
Multiple Airlines
Fri 6/57:20 pm
CHS
- PWM
1 stop4h 38m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$229
This Booking.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Tue 8/116:54 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/10![Breeze Airways logo]()
$231
This Breeze Airways deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:00 am
PWM
- SAV
1 stop4h 39m
Breeze Airways
Sat 7/44:31 pm
SAV
- PWM
1 stop4h 20m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:00 am
PWM
- GSP
1 stop4h 31m
Breeze Airways
Fri 10/167:10 pm
GSP
- PWM
1 stop4h 14m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$253
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:22 am
PWM
- SAV
1 stop4h 44m
American Airlines
Tue 8/256:22 am
SAV
- PWM
1 stop6h 18m
American Airlines
Deal found 5/6![American Airlines logo]()
$287
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
This Breeze Airways deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:00 am
PWM
- SAV
1 stop4h 43m
Breeze Airways
Sat 10/34:55 pm
SAV
- PWM
1 stop4h 24m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$191
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:10 am
PWM
- CHS
1 stop4h 50m
Southwest
Fri 6/57:35 pm
CHS
- PWM
1 stop4h 30m
Southwest
Deal found 5/8![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:57 pm
PWM
- CAE
1 stop4h 49m
Delta
Tue 6/307:01 am
CAE
- PWM
1 stop5h 29m
Delta
Deal found 5/9![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:15 am
PWM
- SAV
2 stops9h 01m
United Airlines
Tue 6/307:15 pm
SAV
- PWM
1 stop4h 36m
United Airlines
Deal found 5/5![United Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
PWM
- CAE
2 stops6h 20m
American Airlines
Sat 5/305:00 am
CAE
- PWM
1 stop4h 51m
American Airlines
Deal found 5/6![American Airlines logo]()
$329
This JetBlue deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:17 pm
PWM
- SAV
1 stop5h 03m
JetBlue
Wed 9/27:23 pm
SAV
- PWM
1 stop4h 51m
JetBlue
Deal found 5/8![JetBlue logo]()
$335
This CheapOair deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:00 am
PWM
- CHS
1 stop26h 39m
Multiple Airlines
Fri 6/53:08 pm
CHS
- PWM
Nonstop2h 25m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$379
This Breeze Airways deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:00 am
PWM
- SAV
1 stop4h 39m
Breeze Airways
Sat 7/44:31 pm
SAV
- PWM
1 stop4h 20m
Breeze Airways
Deal found 5/6![Breeze Airways logo]()
$238
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:35 am
PWM
- CHS
2 stops11h 10m
Southwest
Fri 6/197:35 pm
CHS
- PWM
1 stop4h 30m
Southwest
Deal found 5/5![Southwest logo]()
$282
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:10 am
PWM
- SAV
1 stop4h 45m
Southwest
Sat 6/67:20 pm
SAV
- PWM
1 stop4h 20m
Southwest
Deal found 5/7![Southwest logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:15 am
PWM
- CHS
1 stop4h 47m
United Airlines
Mon 9/144:02 pm
CHS
- PWM
2 stops7h 57m
United Airlines
Deal found 5/5![United Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:05 am
PWM
- MYR
1 stop4h 42m
Delta
Sat 9/1211:00 am
MYR
- PWM
1 stop6h 00m
Delta
Deal found 5/9![Delta logo]()
$347
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:15 am
PWM
- CHS
1 stop4h 47m
United Airlines
Wed 9/27:00 am
CHS
- PWM
1 stop6h 54m
United Airlines
Deal found 5/5![United Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:04 am
PWM
- CHS
2 stops6h 26m
American Airlines
Mon 6/17:47 pm
CHS
- PWM
1 stop4h 12m
American Airlines
Deal found 5/9![American Airlines logo]()
$382
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:41 pm
PWM
- CAE
1 stop5h 33m
Delta
Wed 7/156:01 pm
CAE
- PWM
1 stop5h 13m
Delta
Deal found 5/5![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:30 am
PWM
- CHS
1 stop4h 40m
Southwest
Thu 6/117:35 pm
CHS
- PWM
1 stop4h 30m
Southwest
Deal found 5/5![Southwest logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:00 am
PWM
- GSP
1 stop4h 31m
Breeze Airways
Fri 10/168:32 pm
GSP
- PWM
2 stops19h 52m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$390
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
PWM
- GSP
2 stops8h 20m
United Airlines
Tue 6/237:40 pm
GSP
- PWM
1 stop4h 11m
United Airlines
Deal found 5/7![United Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:02 am
PWM
- MYR
2 stops10h 05m
Delta
Thu 5/2811:32 am
MYR
- PWM
1 stop4h 35m
Delta
Deal found 5/8![Delta logo]()
$362
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:18 pm
PWM
- AGS
1 stop6h 55m
American Airlines
Wed 7/297:30 am
AGS
- PWM
1 stop4h 41m
American Airlines
Deal found 5/6![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:57 pm
PWM
- MYR
1 stop5h 02m
Delta
Tue 6/2311:32 am
MYR
- PWM
1 stop4h 23m
Delta
Deal found 5/8![Delta logo]()
$362
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
PWM
- CAE
2 stops11h 05m
United Airlines
Wed 7/157:45 pm
CAE
- PWM
1 stop4h 06m
United Airlines
Deal found 5/5![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:50 pm
PWM
- MYR
1 stop4h 00m
Southwest
Fri 6/58:10 pm
MYR
- PWM
1 stop3h 55m
Southwest
Deal found 5/5![Southwest logo]()
$364
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:04 am
PWM
- GSP
2 stops6h 03m
American Airlines
Sun 5/316:32 pm
GSP
- PWM
1 stop5h 19m
American Airlines
Deal found 5/5![American Airlines logo]()
$422
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:45 am
PWM
- GSP
1 stop4h 30m
Southwest
Sat 9/268:40 am
GSP
- PWM
1 stop6h 20m
Southwest
Deal found 5/8![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
PWM
- SAV
2 stops9h 04m
United Airlines
Wed 9/26:45 am
SAV
- PWM
1 stop7h 10m
United Airlines
Deal found 5/9![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:50 pm
PWM
- GSP
1 stop5h 03m
Delta
Sat 5/305:05 pm
GSP
- PWM
1 stop6h 04m
Delta
Deal found 5/5![Delta logo]()
$375
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:30 am
PWM
- CHS
2 stops12h 00m
Southwest
Fri 6/51:30 pm
CHS
- PWM
2 stops10h 35m
Southwest
Deal found 5/5![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
PWM
- CHS
1 stop7h 58m
United Airlines
Wed 9/27:00 am
CHS
- PWM
2 stops7h 38m
United Airlines
Deal found 5/8![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:02 am
PWM
- CAE
2 stops11h 00m
Delta
Tue 6/95:35 am
CAE
- PWM
2 stops6h 57m
Delta
Deal found 5/9![Delta logo]()
$381
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated May 10, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated May 10, 2026 and is based on user searches.
This Breeze Airways deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Wed 5/203:20 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$193
This Booking.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Fri 5/223:08 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$248
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:57 pm
PWM
- CHS
1 stop6h 02m
American Airlines
Fri 5/296:42 pm
CHS
- PWM
1 stop5h 09m
American Airlines
Deal found 5/5![American Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:52 am
PWM
- CHS
1 stop22h 46m
Breeze Airways
Wed 6/33:20 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$255
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:04 am
PWM
- CHS
2 stops6h 37m
American Airlines
Wed 6/36:42 pm
CHS
- PWM
1 stop5h 09m
American Airlines
Deal found 5/8![American Airlines logo]()
$268
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:30 pm
PWM
- CHS
Nonstop2h 35m
Multiple Airlines
Fri 6/57:20 pm
CHS
- PWM
1 stop4h 38m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:30 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Fri 6/53:23 pm
CHS
- PWM
2 stops24h 53m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$282
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:10 am
PWM
- SAV
1 stop4h 45m
Southwest
Wed 6/106:30 pm
SAV
- PWM
1 stop4h 25m
Southwest
Deal found 5/6![Southwest logo]()
$287
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:10 am
PWM
- SAV
1 stop4h 45m
Southwest
Sat 6/67:20 pm
SAV
- PWM
1 stop4h 20m
Southwest
Deal found 5/7![Southwest logo]()
$289
This Gotogate deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Mon 6/153:08 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$208
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Fri 6/193:08 pm
CHS
- PWM
Nonstop2h 25m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$270
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:35 am
PWM
- CHS
2 stops11h 10m
Southwest
Fri 6/191:30 pm
CHS
- PWM
2 stops10h 35m
Southwest
Deal found 5/5![Southwest logo]()
$287
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
This Booking.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 5/6![Breeze Airways logo]()
$62
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:57 pm
PWM
- CHS
1 stop5h 51m
American Airlines
Deal found 5/5![American Airlines logo]()
$110
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$117
This Breeze Airways deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
PWM
- SAV
1 stop4h 39m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:00 am
PWM
- GSP
1 stop4h 31m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$131
This Breeze Airways deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$134
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:13 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 5/6![Breeze Airways logo]()
$137
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:57 pm
PWM
- CHS
1 stop5h 39m
Delta
Deal found 5/8![Delta logo]()
$139
This Super.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:29 pm
PWM
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$158
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:15 am
PWM
- MYR
1 stop4h 44m
United Airlines
Deal found 5/9![United Airlines logo]()
$159
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:36 pm
PWM
- CHS
2 stops8h 29m
American Airlines
Deal found 5/6![American Airlines logo]()
$159
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:00 am
PWM
- MYR
1 stop4h 21m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$160
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated May 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $116 (Mytrip) |
One-way from | $62 (Booking.com) |
Popular in | April |
Cheapest in | August |
Average price | $382 |
Good round-trip deal | $242 or less |
Good one-way deal | $108 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Sat 9/26
7:00 am-11:43 am
1 stop4h 43m
Savannah/Hilton Head
Sat 10/3
4:55 pm-9:19 pm
1 stop4h 24m
$191
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Wed 7/1
7:00 am-11:39 am
1 stop4h 39m
Savannah/Hilton Head
Sat 7/4
4:31 pm-8:51 pm
1 stop4h 20m
$238
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Wed 6/3
6:10 am-11:00 am
1 stop4h 50m
Charleston
Fri 6/5
7:35 pm-12:05 am
1 stop4h 30m
$248
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Fri 6/12
5:35 am-4:45 pm
2 stops11h 10m
Charleston
Fri 6/19
7:35 pm-12:05 am
1 stop4h 30m
$282
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Wed 6/3
6:10 am-10:55 am
1 stop4h 45m
Savannah/Hilton Head
Sat 6/6
7:20 pm-11:40 pm
1 stop4h 20m
$289
PortlandColumbia
PWM - CAE
PWMCAE
Portland
Thu 6/25
6:57 pm-11:46 pm
1 stop4h 49m
Columbia Metropolitan
Tue 6/30
7:01 am-12:30 pm
1 stop5h 29m
$315
PortlandSavannah
PWM - SAV
PWMSAV
Portland
Tue 6/23
5:15 am-2:16 pm
2 stops9h 01m
Savannah/Hilton Head
Tue 6/30
7:15 pm-11:51 pm
1 stop4h 36m
$315
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Tue 6/9
5:30 am-10:10 am
1 stop4h 40m
Charleston
Thu 6/11
7:35 pm-12:05 am
1 stop4h 30m
$323
PortlandCharleston
PWM - CHS
PWMCHS
Portland
Wed 9/9
5:15 am-10:02 am
1 stop4h 47m
Charleston
Mon 9/14
4:02 pm-11:59 pm
2 stops7h 57m
$328
PortlandColumbia
PWM - CAE
PWMCAE
Portland
Sat 5/23
6:00 am-12:20 pm
2 stops6h 20m
Columbia Metropolitan
Sat 5/30
5:00 am-9:51 am
1 stop4h 51m
$329
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PWM-CHS
PWM-SAV
PWM-GSP
PWM-CAE
PWM-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PWM-USSC
PWM-CHS
PWM-SAV
PWM-GSP
PWM-CAE
How far ahead should I book a flight from Portland, Maine to South Carolina?
The price you pay for your flight from Portland, Maine to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 74 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Portland, Maine to South Carolina?
Currently, April is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $54). Flying from Portland, Maine to South Carolina in June is currently the most expensive (average of $124). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PWM to SC?
Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 10, 2026.
One of the essential ways to save on airfare from Portland, Maine to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 57% on airfare.
How much does it cost to fly round-trip from Portland, Maine to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 10, 2026.
Read reviews from past customers who have flown Breeze Airways,Southwest, andDelta from Portland to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.2
Boarding
8.3
Overall
8.1
Crew
8.7
Entertainment
6.6
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Boarding
8.3
Overall
8.1
Crew
8.7
Entertainment
6.6
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Boarding
8.3
Overall
8.1
Crew
8.7
Entertainment
6.6
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Boarding
8.3
Overall
8.1
Crew
8.7
Entertainment
6.6
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Boarding
8.3
Overall
8.1
Crew
8.7
Entertainment
6.6
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Boarding
8.3
Overall
8.1
Crew
8.7
Entertainment
6.6
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on May 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$98 | Average$214 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$138 | Average$356 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$401 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$262 | Average$419 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$277 | Average$459 | FlexibilityNo cancel fee | On-time69% |