$496+ Cheap flights from Iowa to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FLO
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Florence
Cheapest
Best
Last-minute
Cheapest flights from Iowa to FlorenceExplore the most affordable flight options available from Iowa to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Iowa to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:33 pm -
2 stops9h 26m
Sat 11/215:09 am -
1 stop6h 39m
Deal found 9/8![American Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:53 pm -
1 stop6h 05m
Tue 10/63:19 pm -
1 stop4h 49m
Deal found 9/10![American Airlines logo]()
$598
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:07 am -
1 stop4h 11m
Sat 10/31:43 pm -
1 stop6h 35m
Deal found 9/10![American Airlines logo]()
$629
Best flights from Iowa to FlorenceDiscover carefully curated flight deals from Iowa to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Iowa to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:33 pm -
2 stops9h 26m
Sat 11/215:09 am -
1 stop6h 39m
Deal found 9/8![American Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
2 stops6h 18m
Tue 10/63:19 pm -
1 stop4h 49m
Deal found 9/10![American Airlines logo]()
$603
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:07 am -
1 stop4h 11m
Sat 10/31:43 pm -
1 stop6h 35m
Deal found 9/10![American Airlines logo]()
$629
Last-minute flights from Iowa to FlorenceDiscover last-minute flight deals from Iowa to Florence. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Florence. Data last updated September 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:53 pm -
1 stop6h 05m
Tue 10/63:19 pm -
1 stop4h 49m
Deal found 9/10![American Airlines logo]()
$598
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:07 am -
1 stop4h 11m
Sat 10/31:43 pm -
1 stop6h 35m
Deal found 9/10![American Airlines logo]()
$629
Find flight deals from Iowa to Florence
Keep the following information in mind while searching for Iowa to Florence flight deals. Data was last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $496 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Iowa to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaFlorence
OMA Omaha Eppley Airfield - FLO Florence
OMAFLO
Omaha Eppley Airfield
Sat 11/14
12:33 pm-10:59 pm
2 stops9h 26m
Florence
Sat 11/21
5:09 am-10:48 am
1 stop6h 39m
$496
MolineFlorence
MLI Moline Quad-City - FLO Florence
MLIFLO
Moline Quad-City
Thu 9/24
6:00 am-1:18 pm
2 stops6h 18m
Florence
Tue 10/6
3:19 pm-7:08 pm
1 stop4h 49m
$603
Quickest round-trip
Cedar RapidsFlorence
CID Cedar Rapids - FLO Florence
CIDFLO
Cedar Rapids
Thu 10/1
8:07 am-1:18 pm
1 stop4h 11m
Florence
Sat 10/3
1:43 pm-7:18 pm
1 stop6h 35m
$629
Sorted by cheapest first
Best time to book a flight from Iowa to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Iowa with our price prediction graph.
OMA-FLO
MLI-FLO
CID-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Florence
USIA-FLO
OMA-FLO
MLI-FLO
CID-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
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